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152 results for “Quorum Sensing”
Data from: Quorum sensing and cheating in bacterial biofilms
The idea from human societies that self-interest can lead to a breakdown of cooperation at the group level is sometimes termed the public goods dilemma. We tested this idea in the opportunistic bacterial pathogen, Pseudomonas aeruginosa, by examining the influence of putative cheats that do not cooperate via cell-to-cell signalling (quorum-sensing, QS). We found that: (i) QS cheating occurs in biofilm populations owing to exploitation of QS-regulated public goods; (ii) the thickness and density of biofilms was reduced by the presence of non-cooperative cheats; (iii) population growth was reduced by the presence of cheats, and this reduction was greater in biofilms than in planktonic populations; (iv) the susceptibility of biofilms to antibiotics was increased by the presence of cheats; and (v) coercing cooperator cells to increase their level of cooperation decreases the extent to which the presence of cheats reduces population productivity. Our results provide clear support that conflict over public goods reduces population fitness in bacterial biofilms, and that this effect is greater than in planktonic populations. Finally, we discuss the clinical implications that arise from altering the susceptibility to antibiotics.
Data from: Bacterial quorum sensing and metabolic incentives to cooperate
The opportunistic pathogen Pseudomonas aeruginosa uses a cell-cell communication system termed "quorum sensing" to control production of public goods, extracellular products that can be used by any community member. Not all individuals respond to quorum-sensing signals and synthesize public goods. Such social cheaters enjoy the benefits of the products secreted by cooperators. There are some P. aeruginosa cellular enzymes controlled by quorum sensing, and we show that quorum sensing–controlled expression of such private goods can put a metabolic constraint on social cheating and prevent a tragedy of the commons. Metabolic constraint of social cheating provides an explanation for private-goods regulation by a cooperative system and has general implications for population biology, infection control, and stabilization of quorum-sensing circuits in synthetic biology.
Quorum sensing inhibitor against Pseudomonas aeruginosa biofilm
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Data from: Bacterial quorum sensing and metabolic incentives to cooperate
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Data from: Environmental modification via a quorum sensing molecule influences the social landscape of siderophore production
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Data from: Bacterial competition and quorum-sensing signalling shapes the eco-evolutionary outcomes of model in vitro phage therapy
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Data from: Quorum sensing and cheating in bacterial biofilms
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The AHL- and BDSF-dependent quorum sensing systems control specific and overlapping sets of genes in Burkholderia cenocepacia H111
GEO Series GSE41244. Burkholderia cenocepacia H111. 3 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of gene profile in KSHV+ PEL cells changed by bacterial quorum sensing molecules [BCP-1_OdDHL]
GEO Series GSE110173. Homo sapiens. 2 samples. Type: Expression profiling by array.
Genetic and transcriptomic characteristics of RhlR-dependent quorum sensing in cystic fibrosis isolates of Pseudomonas aeruginosa: isolate E113
GEO Series GSE198716. Pseudomonas aeruginosa. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptome analysis of Streptococcus mutans quorum sensing-mediated persisters reveals an enrichment in genes related to stress-defense mechanisms
GEO Series GSE244067. Streptococcus mutans UA159. 6 samples. Type: Expression profiling by high throughput sequencing.
The quorum-sensing agr system protects Staphylococcus aureus from oxidative stress (5 hour growth)
GEO Series GSE206889. Staphylococcus aureus. 6 samples. Type: Expression profiling by high throughput sequencing.
PqsE expands and differentially modulates the RhlR quorum sensing regulon in Pseudomonas aeruginosa
GEO Series GSE200835. Pseudomonas aeruginosa. 12 samples. Type: Expression profiling by high throughput sequencing.
A transcriptome study of DSF-mediated quorum sensing in Xanthomonas axonopodis pv. citri
GEO Series GSE29877. Xanthomonas citri; Xanthomonas citri pv. citri str. 306. 6 samples. Type: Expression profiling by array.
AI-2 quorum sensing in *Yersinia pestis*
GEO Series GSE30342. Yersinia pestis. 54 samples. Type: Expression profiling by array.
Controlling a Necessary Evil: Quorum Sensing Attenuates Virulence in Sodalis praecaptivus.
GEO Series GSE97720. Sodalis praecaptivus. 15 samples. Type: Expression profiling by high throughput sequencing.
Response of Lactobacillus plantarum WCSF1 to the Gram-negative pathogen-associated quorum sensing molecule N-3-oxododecanoyl homoserine lactone.
GEO Series GSE124050. Lactiplantibacillus plantarum. 36 samples. Type: Expression profiling by high throughput sequencing.
Lymph node medulla is a quorum sensing niche for developing dendritic cells [preDC]
GEO Series GSE204815. Mus musculus. 2 samples. Type: Other.
Cryptococcus neoformans sexual reproduction is controlled by a quorum sensing peptide
GEO Series GSE94091. Cryptococcus deneoformans. 64 samples. Type: Expression profiling by high throughput sequencing.
Bacterial nucleoside catabolism controls quorum sensing and commensal-to-pathogen transition in the Drosophila gut
GEO Series GSE140194. Pectobacterium carotovorum. 2 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.