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3,050 results for “ablation”
Microscopy image sequences and annotated kymographs of laser ablation experiments in Drosophila embryos
<p><strong>Content</strong></p> <p>This dataset contains 15 2D time-lapse fluorescence microscopy image sequences recorded with confocal laser-scanning microscopy. Each movie shows an epithelial tissue laser nanoablation experiment conducted in a Drosophila embryo.</p> <p>For each sequence, the dataset contains kymographs (one-dimensional space-time plots) of a supracellular cable that is cut during the ablation, and manually created tracks of visible features, such as the resulting cut ends. These tracks allow to estimate, for instance, recoil velocities of the cut tissue and may be used to evaluate automated methods for estimating said velocities.</p> <p>This dataset is used in the manuscript to evaluate various variational approaches for joint motion estimation and source identification:</p> <p>L. F. Lang, N. Dutta, E. Scarpa, B. Sanson, C.-B. Schönlieb, and J. Étienne. Joint Motion Estimation and Source Identification using Convective Regularisation with an Application to the Analysis of Laser Nanoablations. 2019.</p> <p><strong>Description</strong></p> <p>The movies depict a square region of approximately <span class="math-tex">\(42.2 \times 42.2 \, \mathrm{\mu m}^{2}\)</span> at a spatial resolution of <span class="math-tex">\(250 \times 250\)</span> pixels. A typical sequence contains between 60 and 100 frames. They temporal interval between recorded frames was <span class="math-tex">\(727.67 \, \mathrm{ms}\)</span>.</p> <p>Each sequence features cell membranes labelled with E-cadherin:GFP and shows a single plasma-induced laser nanoablation. The destructed tissue region is roughly of <span class="math-tex">\(2 \, \mathrm{\mu m}\)</span> length. This ablation is expected to have a width of the order of the size of one pixel. During the ablation the acquisition is paused, resulting in a black image.</p> <p>For the used microscopy techniques and for the preparation of flies, as well as for the details of the laser ablation method, see the paper:</p> <p>E. Scarpa, C. Finet, G. B. Blanchard, and B. Sanson. Actomyosin-driven tension at compartmental boundaries orients cell division independently of cell geometry In Vivo. Dev. Cell, 47(6):727–740.e6, December 2018. URL: <a href="https://doi.org/10.1016/j.devcel.2018.10.029">https://doi.org/10.1016/j.devcel.2018.10.029</a></p> <p>The kymographs and the manually created annotations (tracks) of features were created using Fiji (<a href="https://fiji.sc/">https://fiji.sc/</a>).</p> <p><strong>Content</strong></p> <p>The dataset contains 15 sequences placed in the following folder structure:</p> <ul> <li>SqAX3_SqhGFP42_GAP43_TM6B <ul> <li>190216E4PSB1</li> <li>190216E5PSB1</li> <li>190216E5PSB2</li> <li>190216E6PSB1</li> <li>190216E8PSB1</li> <li>E2PSB1</li> <li>E5PSB2</li> <li>E8PSB1</li> <li>PSB1E1</li> <li>PSB4</li> </ul> </li> <li>SqhGFP40 <ul> <li>e1_PSB8</li> <li>e3_PSB9</li> <li>e3_PSB10</li> <li>e4_PSB11</li> <li>e4_PSB12</li> </ul> </li> </ul> <p>Each folder contains:</p> <ul> <li>The sequence itself in TIF format, e.g. "190216E4PSB1PMT - PMT [560-] _C1.ome.tif".</li> <li>A file "reslice.roi" that indicates the location/direction of the cut supracellular cable.</li> <li>3 different kymographs for each sequence obtained by taking avg/max/sum projections in Fiji orthogonal to the line specified in "reslice.roi", e.g. <ul> <li>"AVG_Reslice of 190216E4PSB1PMT.tif",</li> <li>"MAX_Reslice of 190216E4PSB1PMT.tif",</li> <li>"SUM_Reslice of 190216E4PSB1PMT.tif".</li> </ul> </li> <li>Text files that state the time/space coordinates of manually tracked features in the kymographs, e.g. <ul> <li>"cutend_L.txt" (coordinates of the left cut end after the ablation),</li> <li>"cutend_R.txt" (coordiantes of the right cut end),</li> <li>"feat_X.txt" (coordinates of additional features, where X is a number and L or R).</li> </ul> </li> <li>A ZIP file "manual_ROIs.zip" that contains all the coordinates of tracked features of the kymograph in ROI format (e.g. "cutend_L.roi").</li> </ul> <p><strong>Usage</strong></p> <p>The sequences, kymographs, and the tracks can be viewed using, for example, Fiji.</p> <p>For the automated analysis, see the Python code that accompanies the manuscript above. It is available at https://dx.doi.org/XXX</p> <p><strong>License information</strong></p> <p>This dataset is released under Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. See <a href="https://creativecommons.org/licenses/by-nc-sa/4.0/">CC BY-NA-SC 4.0</a>.</p> <p><strong>How to cite this dataset</strong></p> <p>If you use this dataset in an academic publication, please consider citing the paper:</p> <p>L. F. Lang, N. Dutta, E. Scarpa, B. Sanson, C.-B. Schönlieb, and J. Étienne. Joint Motion Estimation and Source Identification using Convective Regularisation with an Application to the Analysis of Laser Nanoablations. 2019.</p> <p>To cite solely the dataset, please use:</p> <p>L. F. Lang, N. Dutta, E. Scarpa, B. Sanson, C.-B. Schönlieb, and J. Étienne. (2019). Microscopy image sequences and annotated kymographs of laser ablation experiments in Drosophila embryos [Data set]. Zenodo. <a href="https://doi.org/10.5281/zenodo.3257654">http://doi.org/10.5281/zenodo.3257654</a></p>
Projected 21st-century mass change for Northern Hemisphere glaciers including frontal ablation
<p>Glacier mass change projections for Nothern Hemisphere glaciers including frontal ablation (2000 to 2100) used in the publication "Exploring the impact of a frontal ablation parameterization on projected 21st-century mass change for Northern Hemisphere glaciers" (doi: 10.1017/jog.2023.19).</p> <p>Generated using a modified version of the Open Global Glacier Model (OGGM, https://github.com/jmalles/oggm/tree/jog23)</p>
Prospective Elimination Of Distal Coronary Sinus-Left Atrial Connections for Atrial Fibrillation Ablation Trial
ClinicalTrials.gov study NCT03646643. IPD Sharing: YES. Countries: 1. Publications: 5.
Early Venous Reflux Ablation Ulcer Trial
ClinicalTrials.gov study NCT03286140. IPD Sharing: NO. Countries: 1. Publications: 2.
Edoxaban Treatment Versus Vitamin K Antagonist (VKA) in Patients With Atrial Fibrillation (AF) Undergoing Catheter Ablation
ClinicalTrials.gov study NCT02942576. IPD Sharing: YES. Countries: 11. Publications: 10.
Predicting arrhythmia recurrence post-ablation in atrial fibrillation using explainable machine learning: Code repository
Open the record for dataset details and reuse information.
Predicting arrhythmia recurrence post-ablation in atrial fibrillation using explainable machine learning: Atrial meshes
Open the record for dataset details and reuse information.
Chemical and sediment characteristics of ice cores collected from the ablation zones of Canada, Commonwealth, Howard, Hughes, and Seuss Glaciers in the McMurdo Dry Valleys, Antarctica from 2015 to 2019
This data package contains chemical and sediment characteristics of ice cores collected from the ablation zones of five glaciers in Taylor Valley, located in the McMurdo Dry Valleys region of Antarctica, during the 2015-16, 2016-17, 2017-18, and 2018-19 austral summers. Specifically, shallow ice cores were collected from the ablation zones of Hughes, Howard, Seuss, Commonwealth, and Canada Glaciers in order to characterize the spatial and temporal evolution of ice chemistry and sediment concentration across Taylor Valley. Cores were collected in triplicate from each sampling location and measured 79 mm in diameter and up to 1 m in depth. Cores were sectioned in 5 cm (0-25 cm depth) and 25 cm increments (25 cm to the maximum depth of the core) prior to analyzing chemical and sediment characteristics.
Chemical characteristics of snow in the ablation zone of Canada Glacier in the McMurdo Dry Valleys, Antarctica during the 2016-2017 austral summer
This data package contains chemical characteristics of snow in the ablation zone of Canada Glacier, located in Taylor Valley, McMurdo Dry Valleys, Antarctica during the 2016-17 austral summer. Specifically, snow samples were collected from the ablation zones of Canada and Commonwealth Glaciers to characterize the chemistry of recent snowfall in the ablation zones of these glaciers. Samples were collected in triplicate near mass balance stakes on the same date ice cores were collected as part of a larger study characterizing the spatial and temporal geochemical evolution of glacial meltwater. A subset of snow samples collected from Canada Glacier have been analyzed and are included here. This package may be amended in the future if analysis of the remaining samples from both Canada and Commonwealth Glaciers occurs.
Data from: Ablation of Hoxb3os in mouse polycystic kidney disease exacerbates cystogenesis
<p>Autosomal dominant polycystic kidney disease (ADPKD) is a monogenic disorder characterized by the formation of cysts in the kidney and is primarily caused by mutations in two genes, <em>PKD1</em> and <em>PKD2</em>. In this study, we investigated the role of the long noncoding RNA (lncRNA) <em>Hoxb3os</em> in ADPKD by ablating its expression in the mouse. <em>Hoxb3os</em>-null mice were viable and had grossly normal kidney morphology but displayed activation of mTOR/Akt signaling and subsequent increase in kidney cell proliferation. To determine the role of <em>Hoxb3os</em> in cystogenesis, we crossed the <em>Hoxb3os</em>-null mouse to two orthologous <em>Pkd1</em> mouse models: <em>Pkhd1/Cre</em>;<em>Pkd1<sup>F/F</sup></em> (rapid cyst progression) and <em>Pkd1<sup>RC/RC</sup></em> (slow cyst progression). Ablation of <em>Hoxb3os</em> exacerbated cyst growth in both models. To gain insight into the mechanism whereby <em>Hoxb3os</em> inhibition promotes cystogenesis, we performed proteomic analysis of mTOR/Akt pathway between <em>Pkd1</em> single-knockout (SKO) and <em>Pkd1-Hoxb3os</em> double-knockout (DKO) mice. Compared to SKO, DKO mice presented with enhanced levels of total and phosphorylated Rictor. This was accompanied by increased phosphorylation of Akt<sup>Ser473</sup>, a known mTORC2 effector site. Physiologically, kidneys from DKO mice displayed between 40-50% increase in cell proliferation. Results from this study indicated that ablation of <em>Hoxb3os</em> in mouse PKD exacerbated cystogenesis and dysregulated mTORC2.</p>
Differential Ablation of Organic Coatings from Micrometeoroids Simulated in the Laboratory
<p>The presented data are for an article entitled "Differential Ablation of Organic Coatings from Micrometeoroids Simulated in the Laboratory" that has been submitted for publication to <em>Journal of Geophysical Research - Planets</em>. </p> <p>The file ppy_ablation_data.csv contains the initial mass and initial velocity for each of the 22 PPy-coated olivine dust particle, <br> the gas target pressure, and the charges (in number of electrons) collected by the 16 charge collectors inside the gas target. <br> The value in column "Included" is set to "True" if the particle was among the 18 particles used to calculate charge yields and to fit the model in the article. File Impact_event.zip contains the final impact signals for each of the 22 particles. The impact signals are presented as voltage signals vs. time in CSV format. The units for all data are indicated in the column name. </p> <p> </p>
Investigating the Effects of Laser Wavelengths and Other Ablation Parameters on the Detection of Biogenic Elements and Contaminants in Hydroxyapatite - JAAS - Dataset
<p>The dataset provided contains measurements for an article in The Journal of Analytical Atomic Spectrometry (JAAS). Further details are available in the .txt file included in the folder.</p>
Macrophage Secreted TGF-β1 Contributes to Fibroblast Activation and Ureteral Stricture Following Ablation Injury
<p>Original dataset for figures.</p>
Laser Ablation Tomography of Woody Plants
<p>Movies generated by LATscan from stems of distinct woody vines (climbing plants). Movie 1 illustrates anastomoses and splitting between vascular cylinders in the compound stem of Paullinia pinnata (Sapindaceae), a woody vine normally growing in tropical forests. Movie 2 illustrates the wood and bark of the adult stem of four species of woody vines. The movie starts off showing the transverse view, then reorients to a tangential view. Species name (from left to right): Wisteria floribunda, Gnetum urens, Cocculus orbiculatus and Menispermum canadense. The videos are associated to the paper "Laser ablation tomography (LATscan) as a new tool for anatomical studies of woody plants". </p>
Raw Data for the article: Atrial fibrillation ablation improves late survival after concomitant cardiac surgery
<p><strong>Objective: </strong>Preoperative atrial fibrillation (AF) increases risk of stroke, heart failure, and all-cause mortality after cardiac surgery. Despite encouraging results and guideline recommendations, surgical ablation (SA) for AF concomitant with other heart surgery remains low. In the current study we aimed to address the long-term mortality after SA concomitant with cardiac surgery.</p> <p><strong>Methods: </strong>This report pertains to the HEart surgery In atrial fibrillation and Supraventricular Tachycardia (HEIST) registry. We identified 20,765 adult patients (62% male) with preoperative AF who underwent conventional sternotomy heart surgery between 2010 and 2021 in 8 tertiary centers in Poland, Netherlands, and Italy. We used Cox proportional hazards models for computations and propensity score matching to minimize differences in baseline characteristics.</p> <p><strong>Results: </strong>Of included patients, 2755 (13.4%) underwent SA for AF. The highest rates of SA were observed for mitral interventions (mitral valve repair or replacement and tricuspid intervention, 25.2%), lowest for isolated coronary artery bypass grafting (6.2%). Patients in the SA group were younger (mean age 64.5 ± 9.0 years vs 68.7 ± 16.0 years; P < .001) and lower risk (mean European System for Cardiac Operative Risk Evaluation [EuroSCORE] II, 4.1 vs 5.7; P < .001). During the 11-year study period, there was a mortality reduction associated with SA (hazard ratio, 0.57; 95% CI, 0.52-0.62; P < .001). After propensity matching, 2750 pairs with similar baseline characteristics were identified. SA was associated with 16% mortality decline (hazard ratio, 0.84; 95% CI, 0.75-0.94; P = .003).</p> <p><strong>Conclusions: </strong>In this multicenter, retrospective, propensity matched study, SA concomitant with other cardiac surgery was associated with improved long-term survival regardless of baseline surgical risk.</p>
Change in H2O levels of a milliQ ice sample as a result of laser ablation (100kHz, 50uJ)
<p>This data includes the measured change in water vapour level corresponding to three different laser ablation durations applied to milliQ ice sample. Pulse energy of the laser is 50 uJ and repetition rate is 100kHz. </p> <table> <tbody> <tr> <td>Datetime</td> <td>Laser Ablation Duration (s)</td> </tr> <tr> <td>2019-12-09 11:28</td> <td>20</td> </tr> <tr> <td>2019-12-09 11:33</td> <td>40</td> </tr> <tr> <td>2019-12-09 11:40</td> <td>60</td> </tr> </tbody> </table> <p> </p>
Change in H2O levels of a milliQ ice sample as a result of laser ablation (50kHz, up to 43uJ)
<p>The change in measured water vapour corresponding to 19 and 30 laser ablated craters in a milliQ ice sample. Relevant time period is 2021-05-13 from 16:07 to 16:52.<br> <br> File LA_data_2021-05-13 10.29.58.456138++0200.csv includes data of the laser used for ablation as well as position and speed data of the linear stage that holds the ice sample. <br> <br> File HIDS2159-20210513-150816Z-DataLog_User.dat includes H2O data.</p>
Lung Volume Reduction for Severe Emphysema by Stereotactic Ablative Radiation Therapy
ClinicalTrials.gov study NCT03673176. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Use of Dapagliflozin to Reduce Burden of Atrial Fibrillation in Patients Undergoing Catheter Ablation of Symptomatic Atrial Fibrillation
ClinicalTrials.gov study NCT04792190. IPD Sharing: NO. Countries: 1. Publications: 42.
Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial
ClinicalTrials.gov study NCT02848781. IPD Sharing: NO. Countries: 5. Publications: 2.
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International Brain Laboratory public data
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OpenNeuro
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