Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
555
datasets available to search
ShareScore release 0.9.0
Dataset results
555 results for “albumin”
A Safety, Efficacy and Pharmacokinetics Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Children With Hemophilia B
ClinicalTrials.gov study NCT01662531. IPD Sharing: Not stated. Countries: 10. Publications: 2.
S1505: Combination Chemotherapy or Gemcitabine Hydrochloride and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Before Surgery in Treating Patients With Pancreatic Cancer That Can Be Removed b
ClinicalTrials.gov study NCT02562716. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Albumin To Enhance Recovery After Acute Kidney Injury
ClinicalTrials.gov study NCT04705896. IPD Sharing: YES. Countries: 1. Publications: 1.
Vasoconstrictors as Alternatives to Albumin After Large-Volume Paracentesis (LVP) in Cirrhosis
ClinicalTrials.gov study NCT00108355. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital
ClinicalTrials.gov study NCT04540094. IPD Sharing: YES. Countries: 1. Publications: 1.
Study of Albumin-bound Paclitaxel (Abraxane) in Combination With Carboplatin and Herceptin in Patients With Advanced Breast Cancer
ClinicalTrials.gov study NCT00093145. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Albumin-Bound Paclitaxel and Gemcitabine in Patients With Untreated Stage IV or Recurrent Squamous Cell Lung Cancers
ClinicalTrials.gov study NCT02525653. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Study of Camrelizumab Combined With APatinib and Albumin Paclitacxel in Patients With Advanced Lung Adenocarcinoma
ClinicalTrials.gov study NCT04459078. IPD Sharing: YES. Countries: 1. Publications: 1.
Paclitaxel Albumin-Stabilized Nanoparticle Formulation and Carboplatin in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
ClinicalTrials.gov study NCT00729612. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Effect of Velphoro on Serum Phosphate and Albumin in Peritoneal Dialysis Patients
ClinicalTrials.gov study NCT04046263. IPD Sharing: YES. Countries: 1. Publications: 1.
Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Gemcitabine, and Bevacizumab in Treating Patients With Metastatic Breast Cancer
ClinicalTrials.gov study NCT00662129. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Lucica ® Glycated Albumin-L Clinical Program - Pivotal Study
ClinicalTrials.gov study NCT02489773. IPD Sharing: UNDECIDED. Countries: 1. Publications: 2.
Far-red pentamethine cyanine dyes as fluorescent probes for detection of serum albumins
<p><span>Benzothiazole based cyanine dyes with bridged groups in pentamethine chain were studied as potential far-red fluorescent probes for protein detection. Spectral-luminescent properties were characterized for unbound dyes and in the presence of serum albumins (bovine (BSA), human (HSA), equine (ESA)), and globular proteins (β-lactoglobulin, ovalbumin). We have observed that the addition of albumins leads to a significant increase in dyes fluorescence intensity. However, the fluorescent response of dyes in the presence of other globular proteins was noticeably lower. The value of fluorescence quantum yield for dye bearing sulfonate group complexed with HSA amounted to 42% compared with 0.2 % for the free dye. The detection limit of HSA by this dye was about > 0.003 mg/ml that indicates the high sensitivity of dye to low HSA concentrations. Modeling of structure of the dyes complexes with albumin molecules was performed by molecular docking. According to these data, dyes could bind to up to five sites on the HSA molecule; the most preferable are the hemin-binding site in subdomain IB and <span>the dye-binding site in the pocket between subdomains IA, IIA, and IIIA.</span> This work confirms that pentamethine cyanine dyes could be proposed as powerful far-red fluorescent probes applicable for highly sensitive detection of albumins.</span></p>
Data from: A cross-sectional study investigating the relationship between pit recovery time and serum albumin levels in bilateral lower extremity pitting oedema
<p><span><strong>Objectives</strong>:</span><span> In this study, we re-evaluated the relationship between pit recovery time (PRT) and serum albumin levels and elucidated the factors influencing PRT. </span></p> <p><span><strong>Design</strong>:</span><span> Cross-sectional study.</span></p> <p><span><strong>Setting</strong>:</span><span> Patients who visited the outpatient department or were admitted to a small urban hospital in Japan.</span></p> <p><span><strong>Participants</strong>:</span><span> 135 adult Japanese patients</span> <span>with bilateral lower extremity pitting oedema.</span></p> <p><span><strong>Interventions</strong>: </span></p> <p><strong><span>Primary and secondary outcome measures</span></strong><span>: This study assessed the correlation between PRT and serum albumin levels, calculated the predictive accuracy for identifying a group with low albumin levels when the PRT of the lower leg was < 40 s, and identified variables that influence PRT.</span></p> <p><span><strong>Results</strong>:</span><span> We found no significant correlation between lower leg PRT and serum albumin levels. Furthermore, a PRT of < 40 s was largely ineffective in predicting low albumin levels. Factors influencing PRT included the diagnosis of malnutrition oedema, examinations conducted during hospitalisation, diagnosis of cardiac oedema, use of diuretics, thickness of the lower limb soft tissue, serum creatinine level, estimated right ventricular systolic pressure (RVSP), age, serum albumin level, potassium level, and blood urea nitrogen to serum creatinine ratio. Notable correlations with PRT were observed in relation to lower limb soft tissue thickness, age, and estimated RVSP.</span></p> <p><span><strong>Conclusions</strong>:</span><span> Given that the PRT is influenced by multiple factors, its correlation with serum albumin levels is weak. Thus, predicting hypoalbuminaemia based solely on PRT is inaccurate.</span></p>
Neutrophil-mediated oxidative stress and albumin structural damage predict COVID-19-associated mortality
<p>This work reports that COVID-19-induced oxidative stress inflicts structural damages to human serum albumin (HSA) and is linked with mortality outcome in critically ill patients. Analyzing blood samples from patients and healthy individuals, the paper provides evidence that neutrophils are major sources of oxidative stress in blood and that hydrogen peroxide is highly accumulated in plasmas of non-survivors. The electron paramagnetic resonance spectra of spin-labeled fatty acids (SLFAs) bound with HSA in whole blood of control, survivor, and non-survivor subjects (n=10–11) were analyzed to probe structural damages to the protein. Non-survivors' HSA showed dramatically altered biophysical parameters that reflect remarkably fluid protein microenvironments. Following loading/unloading of 16-DSA, the results show that the transport function of HSA may be impaired in severe patients. Stratified at the means, Kaplan–Meier survival analysis indicated that lower values of S/W ratio and accumulated H<sub>2</sub>O<sub>2</sub> in plasma significantly predicted in-hospital mortality.</p>
Spectroscopy study of albumin interaction with negatively charged liposome membranes: Mutual structural effects of the protein and the bilayers
<p>Deconvolution of the signals of carbonyl groups in the ATR-FTIR spectra of lipids in the region 1700–1760 cm<sup>−1</sup> obtained during liposome incubation with albumin.</p>
Albumin and fibrinogen synthesis rates in advanced chronic liver disease
<p>Supplement data for the research work on "<strong>Albumin and fibrinogen synthesis rates in advanced chronic liver disease".</strong></p> <p>Table S1 and table S2.</p>
Camrelizumab Combined With Albumin-bound Paclitaxel and S-1 in the Treatment of Advanced Gastric Cancer
ClinicalTrials.gov study NCT04675866. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety and Efficacy of Albumin Interferon Administered Every 4 Weeks in Genotype 2/3 Hepatitis C Patients
ClinicalTrials.gov study NCT00759200. IPD Sharing: Not stated. Countries: 12. Publications: 1.
Human Albumin for the Treatment of Ascites in Patients With Hepatic Cirrhosis
ClinicalTrials.gov study NCT01288794. IPD Sharing: Not stated. Countries: 1. Publications: 6.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.