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ShareScore release 0.9.0
Dataset results
161 results for “aneuploidy”
Feasibility Study of a New Screening Program for Major Aneuploidies (T21, T18, T13) in the Emilia-Romagna Region (SAPERER)
ClinicalTrials.gov study NCT04437992. IPD Sharing: NO. Countries: 1. Publications: 0.
MatErnal BLood IS Source to Accurately Diagnose Fetal Aneuploidy
ClinicalTrials.gov study NCT01122524. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Data from: Aneuploidy causes non-genetic individuality
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Data from: Reproductive isolation in a nascent species pair is associated with aneuploidy in hybrid offspring
Speciation may occur when the genomes of two populations accumulate genetic incompatibilities and/or chromosomal rearrangements that prevent inter-breeding in nature. Chromosome stability is critical for survival and faithful transmission of the genome, and hybridization can compromise this. However, the role of chromosomal stability on hybrid incompatibilities has rarely been tested in recently diverged populations. Here, we test for chromosomal instability in hybrids between nascent species, the 'dwarf' and 'normal' lake whitefish (Coregonus clupeaformis). We examined chromosomes in pure embryos, and healthy and malformed backcross embryos. While pure individuals displayed chromosome numbers corresponding to the expected diploid number (2n = 80), healthy backcrosses showed evidence of mitotic instability through an increased variance of chromosome numbers within an individual. In malformed backcrosses, extensive aneuploidy corresponding to multiples of the haploid number (1n = 40, 2n = 80, 3n = 120) was found, suggesting meiotic breakdown in their F1 parent. However, no detectable chromosome rearrangements between parental forms were identified. Genomic instability through aneuploidy thus appears to contribute to reproductive isolation between dwarf and normal lake whitefish, despite their very recent divergence (approx. 15–20 000 generations). Our data suggest that genetic incompatibilities may accumulate early during speciation and limit hybridization between nascent species.
Embryos With Preimplantation Genetic Testing for Aneuploidies (PGT-A) Inconclusive Result: Clinical Implications
ClinicalTrials.gov study NCT04734769. IPD Sharing: NO. Countries: 0. Publications: 2.
Non-invasive Preimplantation Genetic Testing for Aneuploidies Using Cell-free DNA in Spent Culture Media
ClinicalTrials.gov study NCT04711239. IPD Sharing: UNDECIDED. Countries: 0. Publications: 10.
Data from: Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast
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Data from: Reproductive isolation in a nascent species pair is associated with aneuploidy in hybrid offspring
Open the record for dataset details and reuse information.
Genome-wide gene expression analysis of Y-chromosome aneuploidy strains of Drosophila melanogaster
GEO Series GSE93699. Drosophila melanogaster. 30 samples. Type: Expression profiling by high throughput sequencing.
KaryoCreate: a CRISPR-based technology to study chromosome-specific aneuploidy by targeting human centromeres
GEO Series GSE217325. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide small RNAs expression analysis of Y-chromosome aneuploidy strains of Drosophila melanogaster
GEO Series GSE93700. Drosophila melanogaster. 12 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Distinct Adaptive Mechanisms Drive Recovery from Aneuploidy Caused by Loss of the Ulp2 SUMO Protease [WGS]
GEO Series GSE121899. Saccharomyces cerevisiae. 3 samples. Type: Other.
Aneuploidy, oncogene amplification, and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells
GEO Series GSE45129. Mus musculus. 95 samples. Type: Expression profiling by array; Genome variation profiling by array.
Aneuploidy as a mechanism for stress-induced liver adaptation
GEO Series GSE38963. Mus musculus. 8 samples. Type: Genome variation profiling by genome tiling array.
Experimental evolution identifies adaptive aneuploidy as a mechanism of fluconazole resistance in Candida auris
GEO Series GSE136768. Candidozyma auris. 6 samples. Type: Expression profiling by high throughput sequencing.
Increased levels of aneuploidy and deregulation of ploidy controlling genes are associated with maintained cultures of hMSC
GEO Series GSE39250. Homo sapiens. 8 samples. Type: Expression profiling by array.
Recurrent inactivation of STAG2 in bladder cancer is not associated with aneuploidy [GPL6983]
GEO Series GSE51640. Homo sapiens. 45 samples. Type: SNP genotyping by SNP array; Genome variation profiling by SNP array.
Acute deletion of TET enzymes results in aneuploidy in mouse embryonic stem cells through decreased expression of Khdc3 (Whole Genome Sequencing [Low Coverage])
GEO Series GSE214402. Mus musculus. 11 samples. Type: Other.
The Genetic Basis of Aneuploidy Tolerance in Wild Yeast
GEO Series GSE132425. Saccharomyces cerevisiae. 52 samples. Type: Expression profiling by high throughput sequencing.
Maternal ELL3 loss-of-function leads to oocyte aneuploidy and early miscarriage
GEO Series GSE268181. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.