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19,545 results for “chronic”
Genome-wide association summary statistics for sex- and age-specific analysis of chronic back pain
<p>The dataset comprises summary-level statistics for age- and sex-specific genome-wide association study of chronic back pain (cBP) in individuals of European descent from UK Biobank (<a href="https://www.ukbiobank.ac.uk/">https://www.ukbiobank.ac.uk/</a>). The study was carried out under UK Biobank approved project #18219. </p> <p><strong>The dataset accompanies the paper (please cite if using the dataset):</strong></p> <p><a href="https://pubmed.ncbi.nlm.nih.gov/33021770/">Freidin, Maxim B.; Tsepilov, Yakov A.; Stanaway, Ian B.; Meng, Weihua; Hayward, Caroline; Smith, Blair H.; Khoury, Samar; Parisien, Marc; Bortsov, Andrey; Diatchenko, Luda; Børte, Sigrid; Winsvold, Bendik S.; Brumpton, Ben M.; Zwart, John-Anker; HUNT All-In Pain; Aulchenko, Yurii S.; Suri, Pradeep; Williams, Frances M.K. Sex- and age-specific genetic analysis of chronic back pain. Pain. 2020. doi:10.1097/j.pain.0000000000002100.</a></p> <p>The phenotype of cBP was defined as back pain for 3+ months. Linear mixed-effects additive model was fitted adjusting for age, genotyping array type, and 10 genetic PCs provided by UK Biobank. The following filters were applied: minor allele frequency >0.001, genotyping and individual call rates >0.98%, imputation quality score (INFO) >0.7. GWAS were carried out in males and females separately in the whole sample (<strong>allages</strong>) as well as in groups of younger than 65 years (<strong>under65</strong>) and 65+ years old (<strong>65plus</strong>) as detailed in the paper. Accordingly, 6 files are deposited here, corresponding to each group. </p> <p><strong>Column headers:</strong></p> <p>SNP, SNP rsID </p> <p>CHR, chromosome</p> <p>BP, genomic position (GRCh37 build)</p> <p>EA, effect allele (coded as "1")</p> <p>OTHER, other allele (coded as "0")</p> <p>A1FREQ, frequency of effect allele</p> <p>INFO, imputation quality</p> <p>BETA, effect size (for effect allele)</p> <p>SE, standard error of effect size</p> <p>PVAL, p-value for association</p>
Annexes A and B to EFSA Scientific report "Chronic dietary exposure to inorganic arsenic"
<p><strong>Annex A-</strong> Contains the raw occurrence dataset on arsenic as extracted from the EFSA DWH on 30 April 2020 (no data cleaning applied), with the food samples presented in the scientific report as described in its section 2.1. Occurrence data. The data are provided in csv format. This dataset is compliant with EFSA SSD model and contains two additional columns documenting issues identified in the cleaning process (column: issue) and the action taken (column: action) to address the issue (e.g. deleted record or updated values in specific fields). The link to the catalogues of controlled terminologies can be found under "Related identifiers”. </p> <p><strong>Annex B-</strong> Contains summary statistics on occurrence data, consumption data, and dietary exposure assessment results.</p> <p>Table B1. Dietary surveys per country and age group available in the EFSA Comprehensive Database considered in the chronic dietary exposure assessment to inorganic arsenic.</p> <p>Table B2. Analytical data on iAs after data cleaning and analysis steps (13,608 analytical results).<br> Table B3. Occurrence values of inorganic arsenic in food (µg/kg) as used for the exposure assessment.<br> Table B4. Occurrence values of total arsenic in food (µg/kg).<br> Table B5. Summary of the chronic dietary exposure assessment to inorganic arsenic (µg/kg bw per day).<br> Table B6. Detailed chronic dietary exposure assessment to inorganic arsenic (µg/kg bw per day) by European dietary surveys and age classes.</p> <p>Table B7. Main contributing food groups (%) to the mean LB and UB chronic dietary exposure to inorganic arsenic across European dietary surveys and age classes.</p> <p>Table B8. Detailed mean contribution of food groups (%) to the mean LB and UB chronic dietary exposure to inorganic arsenic across European dietary surveys and age classes. </p>
Supplementary material: Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta-analysis
<p>Supplementary material for Cochrane review: Janjua S , Mathioudakis AG , Fortescue R , Walker RAE , Sharif S , Threapleton CJD , Dias S . Prophylactic antibiotics for adults with chronic obstructive pulmonary disease: a network meta-analysis. Cochrane Database of Systematic Reviews 2021, Issue 1. Art. No.: <a href="https://archie.cochrane.org/sections/documents/CD013198">CD013198</a>. DOI: <a href="https://archie.cochrane.org/sections/documents/10.1002/14651858.CD013198.pub2">10.1002/14651858.CD013198.pub2</a>.</p>
Experiment data in support of "Segmentation analysis and the recovery of queuing parameters via the Wasserstein distance: a study of administrative data for patients with chronic obstructive pulmonary disease"
<p>This archive contains a ZIP archive, `data.zip`, that itself contains the data used in the final sections of the paper. The remainder of the paper's supporting files are available at <a href="https://github.com/daffidwilde/copd-paper/">github.com/daffidwilde/copd-paper/</a></p> <p>The ZIP archive is structured as follows:</p> <ul> <li>There is a directory, `wasserstein`, for the parameter sweep described in the model construction section of the paper. Its contents are: (i) a file, `main.csv`, describing each parameter and their maximal Wasserstein distance to the observed data, and (ii) three directories, `best`, `median` and `worst`, each containing the simulated queuing results (in `main.csv`) from that sweep with the best, median and worst found parameter sets, respectively (in `params.txt`).</li> <li>The remaining three directories correspond to the experiments conducted in the final section of the paper. Each directory contains two files: (i) `system_times.csv` which holds trial parameters and system time records for every patient to pass through the model in that experiment, and (ii) `utilisations.csv` which holds trial parameters and utilisations for each server in the model for that experiment.</li> </ul>
Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain
<p>The dataset (CWP_GWAS_EU_ANCESTRY_UKB.txt) contains summary statistics for discovery GWAS of chronic widespread pain based on northern Europeans from UK Biobank comprising 6,914 cases of chronic widespread musculoskeletal pain and 242,929 controls. The sensitivity GWAS (CWP_sensitivity_GWAS_EU_ANCESTRY_UKB.txt) dataset contains summary statistics derived from 6,914 cases of chronic widespread musculoskeletal pain and 223,606 controls. Methodological details available here, https://doi.org/10.1101/2020.11.30.20241000 </p> <p> </p> <p> </p> <p> </p>
Mural cells sustain a homeostatic vascular macrophage niche limiting chronic inflammation
<p>If you use any of these data, please cite the corresponding publication:</p><p><a href="https://doi.org/10.1016/j.immuni.2023.08.002">Mural cell-derived chemokines provide a protective niche to safeguard vascular macrophages and limit chronic inflammation</a><br><a href="https://doi.org/10.1016/j.immuni.2023.08.002">Pekayvaz et al., Immunity, 2023</a> . ( <a href="https://doi.org/10.1016/j.immuni.2023.08.002">https://doi.org/10.1016/j.immuni.2023.08.002</a> )</p><p><strong>scRNA-seq data</strong></p><p><i>processed:</i></p><p>processed_kidney_seurat.Rds<br>processed_lung_seurat.Rds</p><p><i>count matrices:</i></p><p>sample_M1_raw_feature_bc_matrix.h5<br>sample_M2_raw_feature_bc_matrix.h5</p><p><i>script:</i></p><p>process_sctransform.R</p><p>functions.R with helper functions (mainly for plotting) used in the process-script.</p><p><strong>RNA-seq</strong></p><p><i>macrophages:</i></p><p>macs_control_vs_knockout.hisat2.DirectDESeq2.tsv|xlsx (count data and DESeq2 results)</p><p><i>aorta:</i></p><p>aorta_control_vs_knockout.hisat2.DirectDESeq2.tsv|xlsx (count data and DESeq2 results)</p><p><i>Dead vs. Living:</i></p><p>peri_Dead_vs_Living.exon_all.DirectDESeq2.tsv|xlsx (count data and DESeq2 results)</p><p> </p>
An exposome atlas of serum reveals risk of chronic diseases in Chinese population
<p>Although adverse environmental exposures are considered to be a major cause to chronic diseases, current studies have provided limited knowledge on real-world chemical exposures and related risks. Here, we collected serum samples from 5696 healthy people and patients, including 12 chronic diseases in China, and completed serum biomonitoring containing 267 chemicals using gas and liquid chromatography-tandem mass spectrometry. 74 high-frequently detected exposures were used for exposure characterization and risk analysis. Results showed that region was the most critical factor influencing human exposure levels, followed by age. Organochlorine pesticides and perfluoroalkyl substances were associated with multiple chronic diseases, and some of them exceeded safe ranges. Mixture effect models showed significant risk effects of exposure on hyperlipidemia, metabolic syndrome and hyperuricemia. Overall, this study provided a comprehensive human serum exposure atlas and its disease risk, which could guide subsequent more in-depth cause-and-effect studies between environmental exposures and human health. The R codes and related example data for statistical analysis and figure production have been deposited to the GitHub (https://github.com/youlei2023/ExposomeAtlas).</p>
Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids
<p><strong>Abstract: </strong>Disruptions in the tightly regulated process of human brain development have been linked to increased risk for brain and mental illnesses. While the genetic contribution to these diseases is well established, important environmental factors have been less studied at molecular and cellular levels. In this study, we used single-cell and cell-type-specific techniques to investigate the effect of glucocorticoid (GC) exposure, a mediator of antenatal environmental risk, on gene regulation and lineage specification in unguided human neural organoids. We characterized the transcriptional response to chronic GC exposure during neural differentiation and studied the underlying gene regulatory networks by integrating single-cell transcriptomics- with chromatin accessibility data. We found lasting cell type-specific changes that included autism risk genes and several transcription factors associated with neurodevelopment. Chronic GCs influenced lineage specification primarily by priming the inhibitory neuron lineage through key transcription factors like PBX3. We provide evidence for convergence of genetic and environmental risk factors through a common mechanism of altering lineage specification.</p>
Dataset in support of an AI-aided chronic mixture risk assessment along a small European river
<p>Here, we make available a dataset to perform an AI-aided multi-scenario chronic mixture risk assessment. In 2021, river-water samples were collected at six sampling sites along the Holtemme River in Central Germany using large-volume solid phase extraction. The extracts were analysed by target chemical analysis for contaminants of emerging concern. The dataset of the chemical analysis was already published and can be found at DOI: 10.5281/zenodo.10892038. Furthermore, a detailed description of the dataset can be found at DOI: 10.1016/j.dib.2024.110510.</p> <p> </p>
Multiple motor tasks while walking in patients with chronic bilateral and unilateral vestibulopathy
<p><em><span>This dataset contains whole body movements (i.e. 3D trajectories) and 3D kinematics from 30 subjects (10 with bilateral vestibulopathy, 10 with unilateral vestibulopathy, and 10 healthy subjects) during multiple motor tasks while walking: change of speed, double task, gait with eyes closed, gait with head horizontal turns, gait with head vertical turn, step over an obstacle, gait and U-turn. Participants were instrumented with 35 reflective placed on the whole body according to the Convention Gait Model 1.0. </span></em><em><span>A 12-camera motion capture system (Oqus 7+, Qualisys, Göteborg, Sweden), set at a 100 Hz sampling frequency, was used to track cutaneous reflective markers. The marker trajectories were labeled using Qualisys Tracking Manager software (QTM 2019.3, Qualisys, Göteborg, Sweden) and exported in the C3D file format. Joint kinematics were calculated from the raw data of the marker trajectories and stored in C3D files.</span></em></p>
Clinical phenotypes in acute and chronic infarction explained through human ventricular electromechanical modelling and simulations
<p>This dataset includes the meshes, model parameters, and Alya executable binary for simulating acute and chronic stage post-myocardial infarct using Alya, to replicate the results in the article <a href="https://doi.org/10.7554/eLife.93002.1">https://doi.org/10.7554/eLife.93002.1</a></p> <p>For each scenario simulated, a baseline simulation folder is provide with all the required meshes, fields, and model parameters necessary to run an Alya simulation. An additional series of models with variability in ionic conductances is also included for each scenario under the folder <scenario>_pom/, under which 20 simulations are included. For each simulation, only the file describing the ionic conductance scaling factors (ventricular_cell.txt) are included, all other files required to run each particular simulation can be found in the <scenario>_baseline/ version. </p> <p>The file structure is as follows:</p> <ul> <li>Alya executable binary</li> <li>control_baseline</li> <li>control_pom</li> <li>75%_transmural_scar <ul> <li>acute <ul> <li>bz1_baseline</li> <li>bz1_pom <ul> <li>pom_id_0</li> <li>...</li> <li>pom_id_19</li> </ul> </li> <li>bz2_baseline</li> <li>bz2_pom <ul> <li>pom_id_0</li> <li>...</li> <li>pom_id_19</li> </ul> </li> <li>bz3_baseline</li> <li>bz3_pom <ul> <li>pom_id_0</li> <li>...</li> <li>pom_id_19</li> </ul> </li> </ul> </li> <li>chronic <ul> <li>rz1_baseline</li> <li>rz1_pom <ul> <li>pom_id_0</li> <li>...</li> <li>pom_id_19</li> </ul> </li> <li>rz2_baseline</li> <li>rz2_pom <ul> <li>pom_id_0</li> <li>...</li> <li>pom_id_19</li> </ul> </li> </ul> </li> <li>fast_pacing <ul> <li>alternans1</li> <li>alternans4</li> </ul> </li> </ul> </li> </ul> <p>The simulation files in alternans4/ was use to generate results Figure 6 of the accompanying article, and alternans1/ was used to generate results Figure 7. </p> <p>The Alya executable binary has been built on ARCHER2 with the following loaded modules:</p> <p>1) craype-x86-rome <br>2) libfabric/1.12.1.2.2.0.0<br>3) craype-network-ofi <br>4) perftools-base/22.12.0 <br>5) xpmem/2.5.2-2.4_3.30__gd0f7936.shasta <br>6) bolt/0.8 <br>7) epcc-setup-env <br>8) load-epcc-module <br>9) gcc/11.2.0 <br>10) craype/2.7.19 <br>11) cray-dsmml/0.2.2 <br>12) cray-mpich/8.1.23 <br>13) cray-libsci/22.12.1.1 <br>14) PrgEnv-gnu/8.3.3 <br>15) tk/8.6.13 <br>16) tcl/8.6.13 <br>17) cray-python/3.9.13.1<br>18) matplotlib/3.7.2<br><br>To replicate the study, access to an installation of the code in the Nord supercomputer can be requested to <a title="mailto:mariano@elem.bio" href="mailto:mariano@elem.bio">mariano@elem.bio</a></p>
Outdoor air pollution impacts chronic obstructive pulmonary disease deaths in South Asia and China: a systematic review and meta-analysis
<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is among leading causes of death globally. Exposure to outdoor pollution is an important cause for increased mortality and morbidity. This study presents a systemic review regarding the impact of outdoor pollution on COPD mortality in South Asia and China.</p> <p><strong>Methods: </strong>A systematic search was conducted from 1990 to June 30<sup>th</sup> 2020 in English electronic databases: PubMed, Google Scholar and CDSR (Cochrane Database of Systematic Reviews) following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The following terms were used: Chronic Obstructive Pulmonary disease OR COPD OR Chronic Bronchitis OR Emphysema OR COPD Deaths OR Chronic Obstructive Lung Disease OR Airflow Obstruction OR Chronic Airflow Obstruction OR Airflow Obstruction, Chronic OR Bronchitis, Chronic AND Mortality OR Death OR Deceased AND Outdoor pollution, ambient pollution was conducted.</p> <p><strong>Results:</strong> Out of 1899 papers screened only 17 were found eligible to be included. Subjects with COPD exposed to higher levels of outdoor air pollution had a 49% higher risk of death as compared to COPD subjects exposed to lower levels of outdoor air pollution. When taking common air pollutants individually into consideration, PM10 had an odds ratio (OR) of 1.99 respectively at CI 95%, whereas SO2 had OR of 1.8 at 95% CI, and NO2 had an OR of 1.23 OR at 95% CI. These values suggest that there is an effect of outdoor pollution on COPD but not to a significant level.</p> <p><strong>Conclusion: </strong>Despite heterogeneity across selected studies, individuals exposed to outdoor pollutants were found to be at risk of COPD mortality. Though it appears to have risk, COPD mortality was not significantly associated with outdoor pollutants. Controlling air pollution can substantially decrease the risk of COPD in South Asia and China. Further researches including more prospective and longitudinal studies are urgently needed in COPD sub-groups.</p>
Data from: The impact of long-term azithromycin on antibiotic resistance in HIV-associated chronic lung disease
<p><b>Background</b>: Selection for resistance to azithromycin (AZM) and other antibiotics such as tetracyclines and lincosamides remains a concern with long-term AZM use for treatment of chronic lung diseases (CLD). We investigated the impact of 48 weeks of AZM on the carriage and antibiotic resistance of common respiratory bacteria among children with HIV-associated CLD.</p> <p><b>Methods</b>: Nasopharyngeal (NP) swabs and sputa were collected at baseline, 48 and 72 weeks from participants with HIV-associated CLD randomised to receive weekly AZM or placebo for 48 weeks and followed post-intervention until 72 weeks. The primary outcomes were prevalence and antibiotic resistance of <i>Streptococcus pneumoniae</i> (SP), <i>Staphylococcus aureus </i>(SA), <i>Haemophilus influenzae </i>(HI), and <i>Moraxella catarrhalis </i>(MC) at these timepoints. Mixed-effects logistic regression and Fisher's exact test were used to compare carriage and resistance respectively.</p> <p><b>Results</b>: Of 347 (174 AZM, 173 placebo) participants (median age 15 years [IQR =13–18], females 49%),NP carriage was significantly lower in the AZM (n=159) compared to placebo (n=153) arm for SP (18% vs 41%, <i>p</i><0.001)<i>, </i>HI (7% vs 16%, p=0.01)<i>, </i>and MC (4% vs 11%, <i>p</i>=0.02); SP resistance to AZM (62% [18/29] vs 13%[8/63], <i>p</i><0.0001) or tetracycline (60%[18/29] vs 21%[13/63], <i>p</i><0.0001) were higher in the AZM arm. Carriage of SA resistant to AZM (91% [31/34] vs 3% [1/31],<i> p</i><0.0001), tetracycline (35% [12/34] vs 13% [4/31],<i> p</i>= 0.05) and clindamycin (79% [27/34] vs 3% [1/31],<i> p</i><0.0001) was also significantly higher in the AZM arm and persisted at 72 weeks. Similar findings were observed for sputa.</p> <p><b>Conclusions</b>: The persistence of antibiotic resistance and its clinical relevance for future infectious episodes requiring treatment needs further investigation.</p>
Detection of early seeding of Richter transformation in chronic lymphocytic leukemia: scRNA-seq data
<p>Richter transformation (RT) is a paradigmatic evolution of chronic lymphocytic leukemia (CLL) into a very aggressive large B cell lymphoma conferring a dismal prognosis. The mechanisms driving RT remain largely unknown. We characterized the whole genome, epigenome and transcriptome, combined with single-cell DNA/RNA-sequencing analyses and functional experiments, of 19 cases of CLL developing RT. Studying 54 longitudinal samples covering up to 19 years of disease course, we uncovered minute subclones carrying genomic, immunogenetic and transcriptomic features of RT cells already at CLL diagnosis, which were dormant for up to 19 years before transformation. We also identified new driver alterations, discovered a new mutational signature (SBS-RT), recognized an oxidative phosphorylation (OXPHOS)high–B cell receptor (BCR)low-signaling transcriptional axis in RT and showed that OXPHOS inhibition reduces the proliferation of RT cells. These findings demonstrate the early seed- ing of subclones driving advanced stages of cancer evolution and uncover potential therapeutic targets for RT.</p> <p>This repository contains the processed scRNA-seq data (expression matrices, Seurat objects, metadata) related with this publication.</p>
The efficacy of wildlife fences for keeping reindeer outside a chronic wasting disease risk area
<p>Data to</p> <p>"The efficacy of wildlife fences for keeping reindeer outside a chronic wasting disease risk area"</p> <p>accepted in Ecological Solutions and Evidence</p>
Honeybee optomotor behaviour is impaired by chronic exposure to insecticides
<p>Honeybees use wide&[ndash]field visual motion information to calculate the distance they have flown from the hive, and this information is communicated to conspecifics during the waggle dance. Seed treatment insecticides, including neonicotinoids and novel insecticides like sulfoxaflor, display detrimental effects on wild and managed bees, even when present at sublethal quantities. These effects include deficits in flight navigation and homing ability, resulting in decreased survival of exposed worker bees. Neonicotinoid insecticides disrupt visual motion detection in the locust, resulting in impaired escape behaviours, but it had not previously been shown whether seed treatment insecticides disrupt wide&[ndash]field motion detection in the honeybee. Here, we show that sublethal exposure to two commonly used insecticides, imidacloprid (a neonicotinoid) and sulfoxaflor, results in impaired optomotor behaviour in the honeybee. This behavioural effect correlates with altered stress and detoxification gene expression in the brain. Exposure to sulfoxaflor led to sparse increases in neuronal apoptosis, localized primarily in the optic lobes, however there was no effect of imidacloprid. We propose that exposure to cholinergic insecticides disrupts the honeybee&[nprime]s ability to accurately encode wide&[ndash]field visual motion, resulting in impaired optomotor behaviours. These findings provide a novel explanation for previously described effects of neonicotinoid insecticides on navigation and link these effects to sulfoxaflor for which there is a gap in scientific knowledge. --</p>
A network-based approach for isolating the chronic inflammation gene signatures underlying complex diseases towards finding new treatment opportunities
<p>This file contains the data that was used in the paper titled "A network-based approach for isolating the chronic inflammation gene signatures underlying complex diseases towards finding new treatment opportunities" which will be published in Frontiers of Pharmacology.</p>
Dataset for "Quantification of Muscle Fiber Malformations Using Edge Detection to Investigate Chronic Wound Healing"
<p>Primary images, spreadsheets and files for "Quantification of Muscle Fiber Malformations Using Edge Detection to Investigate Chronic Wound Healing"</p>
Intra-host quasispecies reconstructions resemble inter-host variability in transmitted chronic Hepatitis B Virus strains (Dataset)
<p>Data used for publication "Intra-host quasispecies reconstructions resemble inter-host variability in transmitted chronic Hepatitis B Virus strains" submitted to the <em>Journal of Medical Virology</em>. Includes example code and selected sequence, tree, and data files.</p>
Chronic wasting disease alters the movement behavior and habitat use of mule deer during clinical stages of infection
<p>Integrating host movement and pathogen data is a central issue in wildlife disease ecology that will allow for a better understanding of disease transmission. We examined how adult female mule deer (<em>Odocoileus hemionus</em>) responded behaviorally to infection with chronic wasting disease (CWD). We compared movement and habitat use of CWD-infected deer (<em>n</em> = 18) to those that succumbed to starvation (and were CWD-negative by ELISA and IHC; <em>n</em> = 8) and others in which CWD was not detected (<em>n</em> = 111, including animals that survived the duration of the study) using GPS collar data from two distinct populations collared in central Wyoming, USA during 2018–2022. CWD and predation were the leading causes of mortality during our study (32 of 91 deaths attributed to CWD and 27 of 91 deaths attributed to predation). Deer infected with CWD moved slower and used lower elevation areas closer to rivers in the months preceding death compared with uninfected deer that did not succumb to starvation. Although CWD-infected deer and those that died of starvation moved at similar speeds during the final months of life, CWD-infected deer used areas closer to streams with less herbaceous biomass than deer that died of starvation. These behavioral differences may allow for the development of predictive models of disease status from movement data, which will be useful to supplement field and laboratory diagnostics or when mortalities cannot be quickly retrieved to assess cause-specific mortality. Furthermore, identifying individuals that are sick before predation events could help to assess the extent to which disease mortality is compensatory with predation. Finally, infected animals began to slow down around four months prior to death from CWD. Our approach for detecting the timing of infection-induced shifts in movement behavior may be useful in application to other disease systems to better understand the response of wildlife to infectious disease.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.