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37 results for “chytrid”
Data from: Unlocking the story in the swab: A new genotyping assay for the amphibian chytrid fungus Batrachochytrium dendrobatidis
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Data from: Effects of pesticide mixtures on host-pathogen dynamics of the amphibian chytrid fungus
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Data from: Spread of amphibian chytrid fungus across lowland populations of Túngara frogs in Panamá
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Data from: Ancestral chytrid pathogen remains hypervirulent following its long co-evolution with amphibian hosts
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Amphibian resistance to chytridiomycosis increases following low virulence chytrid fungal infection or drug-mediated clearance
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Data from: Opening the file drawer: Unexpected insights from a chytrid infection experiment
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Data from: Sustained immune activation is associated with susceptibility to the amphibian chytrid fungus
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Data from: Joint effects of habitat, zooplankton, host stage structure and diversity on amphibian chytrid
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Chytrid Fungi and Nitrile Gloves Research Data
<p>To prevent transmission of the pathogenic chytrid fungi Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal), hygiene protocols prescribe the single use of disposable gloves for handling amphibians. We discovered that rinse water from nitrile gloves instantly kills 99% of Bd and Bsal zoospores. Transmission experiments using midwife toads (Alytes obstetricans) and Bd, and Alpine newts (Ichthyosaura alpestris) and Bsal, show that the use of the same pair of gloves for 2 subsequent individuals does not result in significant transmission of any chytrid fungus. In contrast, handling infected amphibians bare-handed caused transmission of Bsal in 4 out of 10 replicates, but did not result in transmission of Bd. Based on the manufacturer's information, high resolution mass spectrometry (HRMS) and colorimetric tests, calcium lactate and calcium nitrate were identified as compounds with antifungal activity against both Bd and Bsal. These findings corroborate the importance of wearing gloves as an important sanitary measure in amphibian disease prevention. If the highly recommended single use of gloves is not possible, handling multiple post-metamorphic amphibians with the same pair of nitrile gloves should still be preferred above bare-handed manipulation.</p>
Data from: Skin sloughing rate increases with chytrid fungus infection load in a susceptible amphibian
1. Amphibian chytridiomycosis, caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd), is responsible for the greatest disease-driven loss of vertebrate biodiversity in recorded history. Understanding drivers of host susceptibility to this cutaneous disease is hindered by gaps in our knowledge of the host–pathogen relationship. One such overlooked aspect of susceptibility is variation in skin maintenance processes, particularly skin turnover via routine sloughing. It has been suggested that sloughing plays a role in immune defence, by removing skin-associated microbes. Thus, skin sloughing may play an important role in the pathogenesis of chytridiomycosis. 2. To determine the relationship between skin sloughing and disease progression, we exposed adult Australian green tree frogs (Litoria caerulea) to a local Bd strain and monitored sloughing rates and individual infection loads on a naturalistic cycling temperature regime (15–23 °C). 3. We determined sloughing rates in real-time by using an array of infrared video cameras to film frog behaviour and monitored infection load before and after sloughing by swabbing and analysis with quantitative PCR. 4. We found that sloughing rate increased with Bd infection load in infected frogs, but sloughing itself did not affect Bd load on the ventral skin surface. Furthermore, Bd infection did not affect the duration of characteristic sloughing behaviour, and sloughing retained rhythmicity even at high infection loads. 5. Although an increased sloughing rate might be considered advantageous for Bd-infected animals, it does not appear to curb the progression of disease and may actually contribute to the loss of physiological homoeostasis seen in terminally ill frogs by further inhibiting water and electrolyte transport across the skin. 6. By measuring sloughing rates directly for the first time, our results shed light on how Bd interacts with the physiological processes of the skin and indicate that variation in skin sloughing frequency may play a role in the observed inter- and intraspecific variation in susceptibility to disease.
Data from: Integral Projection Models for host-parasite systems with an application to amphibian chytrid fungus
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Data from: Skin sloughing rate increases with chytrid fungus infection load in a susceptible amphibian
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Chytrid Fungi and Nitrile Gloves Research Data
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Genome-Wide Transcriptional Response of Silurana (Xenopus) tropicalis to Infection with the Deadly Chytrid Fungus
GEO Series GSE16852. Xenopus tropicalis. 26 samples. Type: Expression profiling by array.
Climate as a gatekeeper: Unexpected absence of Batrachochytrium salamandrivorans in an Asian Chytrid hotspot suggests a narrow climatic niche for the pathogen
<p>we conducted an extensive survey for <em>Batrachochytrium salamandrivorans </em>across the Guangxi region of Southern China, now considered a <em>B. dendrobatidis</em> hotspot. We examined 1230 individuals from 38 amphibian species and 36 environmental water bodies sampled. However, PCR testing revealed absence of <em>B. salamandrivorans </em> in our samples. A subsequent niche modeling analysis for <em>B.salamandrivorans </em> suggested that the bioclimatic conditions of much of the region may not be conducive to <em>B. salamandrivorans </em>.</p>
Substrate-specific gene expression in the amphibian chytrid pathogen
GEO Series GSE37135. Batrachochytrium dendrobatidis; Batrachochytrium dendrobatidis JAM81. 12 samples. Type: Expression profiling by array.
Only skin deep: shared genetic response to the deadly chytrid fungus in susceptible frog species
GEO Series GSE34235. Rana muscosa; Rana sierrae. 60 samples. Type: Expression profiling by array.
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Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.