Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
185
datasets available to search
ShareScore release 0.9.0
Dataset results
185 results for “glutathione”
Glutathione and neodiosmin feedback sustain plant immunity
Open the record for dataset details and reuse information.
Dimethylsulfoniopropionate, superoxide dismutase and glutathione as stress response indicators in three corals under short-term hyposalinity stress
Corals are among the most active producers of dimethylsulfoniopropionate (DMSP), a key molecule in marine sulfur cycling, yet the specific physiological role of DMSP in corals remains elusive. Here, we examine the oxidative stress response of three coral species (Acropora millepora, Stylophora pistillata and Pocillopora damicornis) and explore the antioxidant role of DMSP and its breakdown products under short-term hyposalinity stress. Symbiont photosynthetic activity declined with hyposalinity exposure in all three reef-building corals. This corresponded with the upregulation of superoxide dismutase and glutathione in the animal host of all three species. For the symbiont component, there were differences in antioxidant regulation, demonstrating differential responses to oxidative stress between the Symbiodinium subclades. Of the three coral species investigated, only A. millepora provided any evidence of the role of DMSP in the oxidative stress response. Our study reveals variability in antioxidant regulation in corals and highlights the influence life-history traits, and the subcladal differences can have on coral physiology. Our data expand on the emerging understanding of the role of DMSP in coral stress regulation and emphasizes the importance of exploring both the host and symbiont responses for defining the threshold of the coral holobiont to hyposalinity stress.
Underlying data for Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients: an observational study
<p>Underlying data for Evaluation of the antioxidant and anti-inflammatory effect of sublingual glutathione on COPD patients: an observational study</p>
Fig. 4 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 4. The effect of ozone treatment on the antiradical activity (A) and H2O2 level (B) in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the t-Tukey test (p> 0.05). On the figure: ns - not significant.
Fig. 3 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 3. The effect of ozone treatment ATP level (A) and SDH activity in mitochondria (B) in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the t-Tukey test (p> 0.05). On the figure: ns - not significant.
Fig. 1 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 1. The effect of ozone treatment on the glutathione (GSH) level in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the t-Tukey test (p> 0.05). On the figure: ns - not significant.
Fig. 2 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 2. The effect of ozone treatment on the activity of glutathione synthetase (A), glutathione reductase (B) and glutathione peroxidase (C) in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the Tukey test (p> 0.05). On the figure: ns - not significant.
Efficacy and Safety Study of Inhaled Glutathione in Cystic Fibrosis Patients
ClinicalTrials.gov study NCT00506688. IPD Sharing: Not stated. Countries: 1. Publications: 1.
The Production of Reactive Oxygen Species in Response to Glutathione Supplementation and Acute Exercise
ClinicalTrials.gov study NCT02948673. IPD Sharing: NO. Countries: 1. Publications: 20.
Oral Glutathione Supplementation on the Levels of Blood Glutathione
ClinicalTrials.gov study NCT01044277. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Pharmacokinetics and Safety of a New Micellar Glutathione Formulation
ClinicalTrials.gov study NCT06345950. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Restoring Glutathione Synthesis With Tecfidera: An in Vivo H-MRS Single-Arm Study at 7T in Patients With RR MS
ClinicalTrials.gov study NCT02218879. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Glutathione Levels and Compulsivity
ClinicalTrials.gov study NCT02794389. IPD Sharing: UNDECIDED. Countries: 1. Publications: 8.
Oral Glutathione As A Skin Whitening Agent
ClinicalTrials.gov study NCT04105504. IPD Sharing: NO. Countries: 1. Publications: 1.
CNS Uptake of Intranasal Glutathione
ClinicalTrials.gov study NCT02324426. IPD Sharing: Not stated. Countries: 1. Publications: 20.
Glutathione (GSH) Synthesis in Healthy School-aged Children and Healthy Young and Old Adults
ClinicalTrials.gov study NCT02971046. IPD Sharing: NO. Countries: 1. Publications: 2.
Inhaled Glutathione (GSH) Versus Placebo in Cystic Fibrosis
ClinicalTrials.gov study NCT01450267. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Glutathione and Fuel Oxidation in Aging
ClinicalTrials.gov study NCT01870193. IPD Sharing: NO. Countries: 1. Publications: 1.
Investigating the Effect of Diroximel Fumarate on Glutathione in Schizophrenia
ClinicalTrials.gov study NCT06957808. IPD Sharing: NO. Countries: 1. Publications: 13.
Phase IIb Study of Intranasal Glutathione in Parkinson's Disease
ClinicalTrials.gov study NCT02424708. IPD Sharing: Not stated. Countries: 1. Publications: 16.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.