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431
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ShareScore release 0.9.0
Dataset results
431 results for “kidney functions”
Exercise Training and Cognitive Function in Kidney Disease
ClinicalTrials.gov study NCT03197038. IPD Sharing: NO. Countries: 1. Publications: 1.
A Study to Evaluate Safety and Effects of Sotagliflozin 400 and 200 mg on Glucose Control in Participants With Type 2 Diabetes, Severe Impairment of Kidney Function and Inadequate Blood Sugar Control
ClinicalTrials.gov study NCT03242018. IPD Sharing: NO. Countries: 15. Publications: 2.
A Study to Test Whether Different Doses of BI 690517 Alone or in Combination With Empagliflozin Improve Kidney Function in People With Chronic Kidney Disease
ClinicalTrials.gov study NCT05182840. IPD Sharing: YES. Countries: 29. Publications: 2.
Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function
ClinicalTrials.gov study NCT03874117. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study to Test the Effect of Different Doses of Avenciguat (BI 685509) on Kidney Function in People With Chronic Kidney Disease
ClinicalTrials.gov study NCT04736628. IPD Sharing: YES. Countries: 18. Publications: 1.
Nebivolol Effect on Nitric Oxide Levels, Blood Pressure, and Renal Function in Kidney Transplant Patients
ClinicalTrials.gov study NCT01157234. IPD Sharing: Not stated. Countries: 1. Publications: 19.
Effect of Lifestyle Intervention in Patients With Chronic Kidney Disease on Fitness and Immune Function
ClinicalTrials.gov study NCT05649657. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Kidney function, kidney function decline, and the risk of dementia in older adults: a registry-based study
<p><span><b>Objective:</b> Community-based reports regarding the association between the estimated glomerular filtration rate (eGFR) and dementia risk show conflicting results. This study aims is to investigate the links between kidney function, kidney function decline and dementia incidence.</span></p> <p><span><b>Methods:</b> We analyzed the association of eGFR with the risk of dementia (defined as a new dementia diagnosis or initiation of dementia treatments) among 329,822 residents of Stockholm who accessed healthcare during 2006-2011, were ≥65 years, had no history of dementia or underwent kidney replacement therapy. We also estimated the rate of eGFR decline among 205,622 residents with repeated eGFR measurements during the first-year of observation and investigated its association with subsequent dementia risk. </span></p> <p><span><b>Results: </b>18,983 cases of dementia (5.8% of participants) were detected over a median follow-up of 5 years. Dementia incidence rates (IR) were progressively higher with lower eGFR: from 6.56/1000 person-years in persons with eGFR 90-104ml/min to 30.28/1000 person-years in those with eGFR<30ml/min. After multivariable adjustment, lower eGFR was associated with a higher dementia risk [hazard ratio(HR), 1.71; 95% confidence interval(CI), 1.54-1.91 in eGFR 30-59ml/min and HR 2.62, 1.91-3.58 in eGFR<30ml/min] compared with eGFR of 90-104ml/min. A steeper decline in eGFR (decline>2ml/min/1.73m<sup>2</sup>/year) within one year was associated with higher dementia risk. Risk magnitudes were stronger for vascular dementia than for Alzheimer. As many as 10% (95% CI 6-14%) of dementia cases could be attributed to eGFR<60ml/min/1.73m<sup>2</sup>, a proportion higher than that attributed to other dementia risk factors such as cardiovascular disease and diabetes. </span></p> <p><span><span><b>Conclusions:</b> Both lower kidney function and steeper kidney function decline are associated with the development of dementia. </span></span></p>
Furosemide Stress Test Predicting Early Graft Function in Kidney Transplantation
ClinicalTrials.gov study NCT03071536. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes
ClinicalTrials.gov study NCT05936151. IPD Sharing: YES. Countries: 5. Publications: 0.
Preventing Delayed Graft Function in Kidney Transplant Patients
ClinicalTrials.gov study NCT06724211. IPD Sharing: NO. Countries: 1. Publications: 2.
Effect of CPAP in the Worsening of Renal Function in Early Stages of Chronic Kidney Disease (CKD)
ClinicalTrials.gov study NCT03319888. IPD Sharing: NO. Countries: 1. Publications: 23.
A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney Function
ClinicalTrials.gov study NCT06559527. IPD Sharing: YES. Countries: 1. Publications: 0.
The Effect of Remote Postconditioning on Graft Function in Patients Undergoing Living-related Kidney Transplantation
ClinicalTrials.gov study NCT01363687. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study to Evaluate Safety and Tolerability of Iberdomide (CC-220) in Participants With Kidney Impairment Compared to Participants With Normal Kidney Function
ClinicalTrials.gov study NCT04933747. IPD Sharing: YES. Countries: 1. Publications: 0.
A Study of Factors That Affect Long-Term Kidney Transplant Function
ClinicalTrials.gov study NCT00270712. IPD Sharing: Not stated. Countries: 2. Publications: 6.
Deceased Organ Donor Interventions to Protect Kidney Graft Function
ClinicalTrials.gov study NCT02525510. IPD Sharing: NO. Countries: 1. Publications: 6.
Effect of Exercise on Endothelial Function and Vascular Compliance in Chronic Kidney Disease
ClinicalTrials.gov study NCT01068314. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Furosemide Stress Test as a Predictor of Tubular Function in Chronic Kidney Disease
ClinicalTrials.gov study NCT02417883. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Telmisartan Versus Enalapril in Heart Failure With Reduced Ejection Fraction Patients With Moderately Impaired Kidney Functions
ClinicalTrials.gov study NCT04736329. IPD Sharing: YES. Countries: 1. Publications: 1.
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