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48 results for “life course”
HIV Acquisition and Life Course of Born-abroad Men Who Have Sex With Men Living in Ile-de-France: the GANYMEDE Study
ClinicalTrials.gov study NCT04684758. IPD Sharing: NO. Countries: 1. Publications: 0.
Socio-demographic Characteristics of Basic Life Support Course Participants
ClinicalTrials.gov study NCT04251325. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Quality of Life and the Influence of Stress on the Postoperative Course of Patients After Device Implantation
ClinicalTrials.gov study NCT07343466. IPD Sharing: NO. Countries: 1. Publications: 10.
Data from: Inclusive fitness and differential productivity across the life course determine intergenerational transfers in a small-scale human society
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Data from: Cognition at age 70: life course predictors and associations with brain pathologies
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Offspring sex-ratios are stable across the life-course in Drosophila simulans
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Data from: Perinatal lead (Pb) exposure results in sex-specific effects on food intake, fat, weight, and insulin response across the murine life-course
Developmental lead (Pb) exposure has been associated with lower body weight in human infants and late onset obesity in mice. We determined the association of perinatal Pb exposure in mice with changes in obesity-related phenotypes into adulthood. Mice underwent exposure via maternal drinking water supplemented with 0 (control), 2.1 (low), 16 (medium), or 32 (high) ppm Pb-acetate two weeks prior to mating through lactation. Offspring were phenotyped at ages 3, 6, and 9 months for energy expenditure, spontaneous activity, food intake, body weight, body composition, and at age 10 months for glucose tolerance. Data analyses were stratified by sex and adjusted for litter effects. Exposed females and males exhibited increased energy expenditure as compared to controls (p<0.0001 for both). In females, horizontal activity differed significantly from controls (p = 0.02) over the life-course. Overall, food intake increased in exposed females and males (p<0.0008 and p<0.0001, respectively) with significant linear trends at 9 months in females (p = 0.01) and 6 months in males (p<0.01). Body weight was significantly increased in males at the medium and high exposures (p = 0.001 and p = 0.006). Total body fat differed among exposed females and males (p<0.0001 and p<0.0001, respectively). Insulin response was significantly increased in medium exposure males (p<0.05). Perinatal Pb exposure at blood lead levels between 4.1 µg/dL and 32 µg/dL is associated with increased food intake, body weight, total body fat, energy expenditure, activity, and insulin response in mice. Physiological effects of developmental Pb exposure persist and vary according to sex and age.
Data from: Life course analysis of birdsong reveals maturation and senescence of repeatable characteristics
Signalers may benefit in some contexts from advertising their ages, for example in courting potential mates. Receivers in turn may benefit from assessing a signaler's age, even in cases where their doing so is against the signaler's interests. Cues to age contained in signals thus may have important fitness consequences. In birds, males of many species have been shown to display delayed maturation of their songs, resulting in older males singing songs that are higher in quality in one or more characteristics. Conversely, it seems possible that songs might eventually deteriorate with age as an aspect behavioral senescence. Studies of birdsong long enough to test both possibilities are quite uncommon, with nearly all studies of age-dependent changes in birdsong spanning 3 or fewer years of males' lives. Here we present the longest longitudinal analysis of male birdsong to date, in which we analyze songs recorded over up to 11 years of the lives of captive male swamp sparrows. We find that males displayed delayed maturation of three song characteristics: song rate, song length, and consistency between songs. Delayed maturation was followed by behavioral senescence of three characteristics: song rate, stereotypy within songs, and consistency between songs. These results suggest swamp sparrows should be able to use song to distinguish intermediate-aged males from one-year-old and very old males.
Kinetic Tremor in Parkinsons Disease: Its Course Under Pramipexole (Mirapexin®) Treatment and Impact on Quality of Life
ClinicalTrials.gov study NCT01100073. IPD Sharing: Not stated. Countries: 8. Publications: 0.
Life Course, HIV and Hepatitis B Among African Migrants Living in Ile-de-France
ClinicalTrials.gov study NCT02566148. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Life Course Socioeconomic Status, Social Context and Cardiovascular Disease
ClinicalTrials.gov study NCT00014833. IPD Sharing: YES. Countries: 0. Publications: 1.
Data from: Life course analysis of birdsong reveals maturation and senescence of repeatable characteristics
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Data from: Perinatal lead (Pb) exposure results in sex-specific effects on food intake, fat, weight, and insulin response across the murine life-course
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Data from: Drivers of diversification in individual life courses
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Liver sexual dimorphism in key signaling pathways across the rat life course
GEO Series GSE160153. Rattus norvegicus. 24 samples. Type: Expression profiling by high throughput sequencing.
Epigenome-wide DNA Methylation Profiling in the Investigation of Treatment and Life-Course Exposures and Adverse Health Outcomes in Survivors of Childhood Cancer from the St. Jude Lifetime Cohort
GEO Series GSE314261. Homo sapiens. 5013 samples. Type: Methylation profiling by genome tiling array.
Comparison of Two Summative Assessment Methods in Advanced Life Support Courses
ClinicalTrials.gov study NCT03412032. IPD Sharing: NO. Countries: 1. Publications: 0.
Online Interactive Courses on Loneliness and Quality of Life of Older Adults
ClinicalTrials.gov study NCT05007600. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Time Course Effects of Functional Resistance Training on Fitness and Quality of Life Chronic Low Back Pain Patients
ClinicalTrials.gov study NCT05449262. IPD Sharing: NO. Countries: 1. Publications: 0.
Standard Two-Day Advanced Life Support (ALS) Versus One Day Recertification Course
ClinicalTrials.gov study NCT07358741. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.