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Dataset results
381 results for “lung carcinoma”
A Phase I/II Study of Paclitaxel, Carboplatin and YM155 (Survivin Suppressor) in Subjects With Solid Tumors (Phase I) and Advanced Non-Small Cell Lung Carcinoma (Phase II)
ClinicalTrials.gov study NCT01100931. IPD Sharing: Not stated. Countries: 1. Publications: 4.
APX005M With Nivolumab and Cabiralizumab in Advanced Melanoma, Non-small Cell Lung Cancer or Renal Cell Carcinoma
ClinicalTrials.gov study NCT03502330. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Tumor growth kinetics of subcutaneously implanted Lewis Lung carcinoma cells
<p><strong>Please cite</strong><br> Benzekry, S., Lamont, C., Beheshti, A., Tracz, A., Ebos, J. M. L., Hlatky, L., & Hahnfeldt, P. (2014). Classical mathematical models for description and prediction of experimental tumor growth. <em>PLoS Computational Biology</em>, <em>10</em>(8), e1003800. http://doi.org/10.1371/journal.pcbi.1003800</p> <p><strong>Cell culture</strong><br> Murine Lewis lung carcinoma (LLC) cells, originally derived from a spontaneous tumor in a C57BL/6 mouse [1], were obtained from American Type Culture Collection (Manassas, VA). </p> <p><strong>Tumor injections</strong><br> For the subcutaneous mouse syngeneic lung tumor model, C57BL/6 male mice with an average lifespan of 878 days were used [2]. At time of injection mice were 6 to 8 weeks old (Jackson Laboratory, Bar Harbor, Maine). Subcutaneous injections of 10<sup>6</sup> LLC cells in 0.2 ml phosphate-buffered saline (PBS) were performed on the caudal half of the back in anesthetized mice.</p> <p><strong>Tumor measurements</strong><br> Tumor size was measured regularly with calipers to a maximum of 1.5 cm<sup>3</sup> for the lung data set. Largest (L) and smallest (w) diameters were measured subcutaneously using calipers and the formula V = <span class="math-tex">\(\frac{\pi}{6}w^2 L\)</span> was then used to compute the volume (ellipsoid). Volumes ranged 14–1492 mm<sup>3</sup> over time spans from 4 to 22 days for the lung tumor model (two experiments of 10 animals each).</p> <p>[1] Bertram JS, Janik P (1980) Establishment of a cloned line of Lewis Lung Carcinoma cells adapted to cell culture. Cancer Lett 11: 63–73. Available: http://www.ncbi.nlm.nih.gov/pubmed/7226139. Accessed 9 July 2013.</p> <p>[2] Kunstyr I, Leuenberger HG (1975) Gerontological data of C57BL/6J mice. I. Sex differences in survival curves. J Gerontol 30: 157–162. Available: http:// www.ncbi.nlm.nih.gov/pubmed/1123533. Accessed 9 July 2013.</p>
A Riskscore Model for Predicting Survival, Tumor Microenvironment, Immunotherapy and drug sensitivity of Lung Squamous Cell Carcinoma Based on PI3K/AKT/MTOR Pathway-Related Genes
<p>Firstly, the data we provide is the raw data downloaded from the TCGA database. Secondly, we provide the following explanations for the raw data, taking Figure 1 as an example:</p> <p>First, we selected a LUSC dataset from the TCGA database that includes RNA-seq data (FPKM values) and clear clinical information, consisting of 51 normal samples and 501 LUSC samples. The raw data <span>can be found in</span> the "mRNA" document in the "Fig.1" file<span>, and t</span>he data includes TCGA <span>id</span> information.</p> <p>Next, the data was imported into "mRNA_edgeR" to analyze whether the RNA-seq data from these 552 samples meet the criteria of |logFC| > 0.585 and FDR < 0.05, <span>and the results are shown in</span> the "diffSig" table. Subsequently, the genes in the "diffSig" table were intersected with 105 PAGs, <span>and</span> 44 key PAGs <span>were identified, </span>as shown in Figure 1.</p> <p>The <span>other</span> figures can <span>also </span>be reproduced sequentially based on the methods described <span>above</span>.</p> <p>Furthermore, due to the limited number of LUSC patients, the clinical information in the database is relatively incomplete. Hence, the clinical information that we provide constitutes the entire content available in the database.</p>
Pharmacogenomic Study Realized on "Non-small Cell Lung Carcinoma"
ClinicalTrials.gov study NCT00222404. IPD Sharing: Not stated. Countries: 1. Publications: 8.
A Study of 5 Years of Adjuvant Osimertinib in Completely Resected Epidermal Growth Factor Receptor Mutation (EGFRm) Non-small Cell Lung Carcinoma (NSCLC)
ClinicalTrials.gov study NCT05526755. IPD Sharing: YES. Countries: 11. Publications: 1.
A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers
ClinicalTrials.gov study NCT00926640. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Serum Exosomal miRNA Predicting the Therapeutic Efficiency in Lung Squamous Carcinoma
ClinicalTrials.gov study NCT05854030. IPD Sharing: NO. Countries: 1. Publications: 11.
Radical Treatment of Synchronous Oligometastatic Non-Small Cell Lung Carcinoma
ClinicalTrials.gov study NCT02805530. IPD Sharing: NO. Countries: 1. Publications: 5.
Osimertinib Resistance in Patients With Non-small-cell Lung Carcinoma That Have Progressed.
ClinicalTrials.gov study NCT04737382. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
SC-002 in Small Cell Lung Cancer and Large Cell Neuroendocrine Carcinoma
ClinicalTrials.gov study NCT02500914. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Nedaplatin (Jiebaishu®) Combined With Docetaxel for Advanced Lung Squamous Cell Carcinoma
ClinicalTrials.gov study NCT02088515. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Mutations in the Epidermal Growth Factor Receptor(EGFR) Gene in Non-Small Cell Lung Carcinoma (NSCLC) and the Relation to Response of Treatment With Erlotinib
ClinicalTrials.gov study NCT00815971. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Tislelizumab Combined With Chemotherapy as Neoadjuvant Therapy for Stage IIIA-IIIB (N2) Lung Squamous Cell Carcinoma
ClinicalTrials.gov study NCT05024266. IPD Sharing: NO. Countries: 1. Publications: 1.
The Influence of Cancer Stem-cells on Risk of Relapse in Patients Harboring Adenocarcinoma and Squamous Cell Carcinoma of the Lung
ClinicalTrials.gov study NCT04634630. IPD Sharing: NO. Countries: 1. Publications: 2.
Metformin Plus TKI Use in Patients With Non-Small Cell Lung Carcinoma
ClinicalTrials.gov study NCT03071705. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
Nab-Paclitaxel Treatment in Advanced Squamous Cell Carcinoma of Lung
ClinicalTrials.gov study NCT01236716. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Nano Drug Interventional Therapy Using Digital Subtraction Angiography（DSA） for Lung Carcinoma
ClinicalTrials.gov study NCT02449122. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Prognostic Significance of the Lung Immune Prognostic Index (LIPI) in Postoperative Clear Cell Renal Cell Carcinoma: a Multicenter Retrospective Cohort Study
ClinicalTrials.gov study NCT06775574. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of Pembrolizumab (MK-3475) in Participants With Progressive Locally Advanced or Metastatic Carcinoma, Melanoma, or Non-small Cell Lung Carcinoma (P07990/MK-3475-001/KEYNOTE-001)
ClinicalTrials.gov study NCT01295827. IPD Sharing: YES. Countries: 0. Publications: 24.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.