Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
45
datasets available to search
ShareScore release 0.9.0
Dataset results
45 results for “microbial infection”
Microbial infection instigates tau-related pathology in Alzheimer's disease via activating neuroimmune cGAS-STING pathway
GEO Series GSE229411. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
A case for routine microbial diagnostics: Results from antimicrobial susceptibility testing in post-traumatic wound infections at a Ugandan tertiary care hospital
<p><strong>ABSTRACT</strong></p> <p>The global spread of antimicrobial resistance (AMR) is an increasing challenge for clinicians in Uganda, where microbiological diagnostics are not routinely available. The aim of this study was to determine pathogen prevalence and antibiotic resistance patterns in patients with wound infections following trauma at a national referral hospital in Kampala, Uganda. In addition, the suitability of currently used empirical treatment options in this setting was evaluated.</p> <p>This prospective, observational study analysed antimicrobial prescriptions, culture results and antimicrobial sensitivity testing (AST) of wound swabs and blood samples from patients with clinical signs of wound infections on the trauma ward.</p> <p>A total of 124 patients (n=99, 79.8% male) with a median age of 30 years (IQR 23-39) were enrolled between October 2021 and January 2022. Wound infections were classified as nosocomial in 69% of the cases. Pathogens were isolated from 122 wound swabs, yielding 238 bacterial isolates. The most prevalent pathogens were gram-negative bacteria including <em>Escherichia coli </em>(n=48, 20.2%) and <em>Acinetobacter </em>spp. (n=43, 18.1%). Empiric treatment consisted of ceftriaxone and gentamicin which was administered to 67.2% (n=78) and 62.1% (n=72) of patients, respectively. High rates of antimicrobial resistance could be demonstrated across gram-negative and gram-positive species towards the most common empiric antibiotics. Following the AST results, over 95% (n=111) of patients required a change of treatment.</p> <p>Our findings demonstrate that current empiric treatment for wound infections is missing its target in hospitalized patients in Kampala. Increased diagnostic capacity and structured antimicrobial stewardship are necessary to tackle the growing problem of AMR in Uganda.</p>
Microbial Infection and AMR in Hospitalized Patients With Covid 19
ClinicalTrials.gov study NCT04479982. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
ClinicalTrials.gov study NCT01904188. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Effect of Probiotics on Microbial Translocation and Inflammation in HIV-infected Patients
ClinicalTrials.gov study NCT02764684. IPD Sharing: YES. Countries: 1. Publications: 0.
Electroceutical Dressing Technology (EDT) Against Wound Microbial Biofilm Infection
ClinicalTrials.gov study NCT04794621. IPD Sharing: NO. Countries: 1. Publications: 0.
E. Faecalis Prevalence in Primary and Secondary Endodontic Infections: a Pre-post Microbial Analysis Following Chemo-mechanical Preparation
ClinicalTrials.gov study NCT04637659. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Incidence and Microbial Profiles of Periprosthetic Joint Infection After Total Knee Arthroplasty in Obese vs Non-Obese Patients
ClinicalTrials.gov study NCT07398742. IPD Sharing: NO. Countries: 1. Publications: 0.
The Association Between Proinflammatory Cytokines, Microbial Infection and Clinical Manifestation in Sciatica Patients
ClinicalTrials.gov study NCT03432507. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Use of a Microbial Sealant to Reduce Surgical Site Infections.
ClinicalTrials.gov study NCT02241915. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Diagnosis and Bacterial Identification of Periprosthetic Joint Infection With Microbial-ID
ClinicalTrials.gov study NCT05320354. IPD Sharing: UNDECIDED. Countries: 6. Publications: 0.
Microbial Cell-free Metagenomic Sequencing for Suspected Infections in Adult Immunocompromised Outpatients
ClinicalTrials.gov study NCT07110636. IPD Sharing: NO. Countries: 1. Publications: 0.
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
ClinicalTrials.gov study NCT02271243. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Molecular Analysis of Microbial DNA in Infected Necrotizing Pancreatitis
ClinicalTrials.gov study NCT01815489. IPD Sharing: Not stated. Countries: 1. Publications: 0.
RNAseq Analysis of Microbial Gene Expression in Necrotizing Soft Tissue Infections
ClinicalTrials.gov study NCT02025816. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Correlation Between Microbial Infection and Lumbar Degenerative Disease Based on High-throughput Gene Sequencing
ClinicalTrials.gov study NCT06075979. IPD Sharing: NO. Countries: 1. Publications: 0.
Vitamin D promotes tissue repair and host defense responses against microbial infection in airway organoids
GEO Series GSE224094. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Characterization of the microbial community structure in Candidatus Liberibacter asiaticus-infected Citrus plants treated with antibiotics in the field
GEO Series GSE46727. Archaea; Citrus sinensis; Bacteria. 9 samples. Type: Other.
Frequent low-dose THC in adolescence disrupts microglia homeostasis and disables response to microbial infection
GEO Series GSE213734. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Microbial Etiology of Ventilator-associated Pneumonia in COVID-19 Infected Patients
ClinicalTrials.gov study NCT04344509. IPD Sharing: NO. Countries: 0. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.