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37 results for “sex steroids”
Clinical benefits of sex steroids given as a priming prior to GH provocative test or as a growth-promoting therapy in peripubertal growth delays: Results of a retrospective study among ENDO-ERN centres
<p>Objectives: Sex steroids, administered as a priming before GH stimulation tests<br> (GHST) to differentiate between growth hormone deficiency (GHD) and constitutional<br> delay of growth and puberty (CDGP) or as growth-promoting therapy using<br> low-dose sex steroids (LDSS) in CDGP, are much debated. We aimed to compare auxological<br> outcomes of CDGP or GHD children undergoing primed or unprimed GHST<br> and to evaluate LDSS treatment in CDGP.<br> Design: Retrospective study among three paediatric University Hospitals in Italy and<br> UK.<br> Methods: 184 children (72 females) aged 12.4 ± 2.08 years underwent primed (/P+)<br> or unprimed (/P−) GHST and were followed up until final height (FH). CDGP patients<br> were untreated (CDG P−) or received LDSS (CDGP+). The cohort included 34 CDG<br> P−/P+, 12 CDGP+/P+, 51 GHD/P+, 29 CDG P−/P−, 2 CDGP+/P− and 56 GHD/P−. FH<br> standard deviation score (SDS), Δ SDS FH-target height (TH) and degree of success<br> (−1 ≤ Δ SDS FH-SDS TH ≤ +1) were outcomes of interest.<br> Results: GHD/P+ had better FH-SDS (−0.87 vs −1.49; P = .023) and ΔSDS FH-TH<br> (−0.35 vs −0.77; P = .002) than CDGP−/P+. Overall, GHD/P+ showed the highest degree<br> of success (90%, P = .006). Regardless of priming, both rhGH and LDSS improved<br> degree of success compared to no treatment (89% and 86% vs 63%, P = .0009).<br> GHD/P+ showed a trend towards a higher proportion of permanent GHD compared<br> to GHD/P- (30.43% vs 15.09%; P = .067).<br> Conclusion: In peripubertal children, priming before GHST improves diagnostic accuracy<br> of GHST for idiopathic GHD. LDSS treatment improves auxological outcomes<br> in CDGP</p>
Figure 3 in Differential gene expression pattern and plasma sex steroids during testicular development in Genyatremus luteus (Perciforme: Haemulidae) (Bloch, 1790)
Figure 3. Gene expression of er (A) andlhr (B) in the male gonad of Genyatremus luteus individuals at different maturation stages. Columns represent arithmetic mean and standard error of the mean. abc Different letters indicate statistically significant difference (p<0.05).
Data from: Regional difference in sex steroid action on formation of morphological sex differences in the anteroventral periventricular nucleus and principal nucleus of the bed nucleus of the stria terminalis
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Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice
GEO Series GSE238244. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic analysis of the early effects of sex steroid ablation on BM LT-HSCs 2 days post surgery.
GEO Series GSE64841. Mus musculus. 6 samples. Type: Expression profiling by array.
The Effect of Sex Steroid Replacement Therapy in the Hypogonadism and Transgender Active-Duty Population
ClinicalTrials.gov study NCT06247267. IPD Sharing: NO. Countries: 1. Publications: 0.
The Effects of Systemic Isotretinoin Treatment on Adrenal Steroid and Sex Hormones Level in Severe Acne Vulgaris
ClinicalTrials.gov study NCT05903716. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study on Mechanisms of Changes in Liver Disease and Sex Steroid Metabolism During Weight Loss
ClinicalTrials.gov study NCT02964780. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluating Serum Sex Steroid Hormones
ClinicalTrials.gov study NCT00340756. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effects of Sex Steroid Hormones on Human Brain Function, Structure and Connectivity
ClinicalTrials.gov study NCT01292785. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Sex Steroids, Obesity and Lipids in Adolescent Females
ClinicalTrials.gov study NCT00005210. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Post Operative Continuous Active Combination Sex Steroids for the Prevention of Recurrent Endometrioma Formation
ClinicalTrials.gov study NCT00999479. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of 4-Hydroxytamoxifen Gel on Breast Density, Salivary Sex Steroids, and Quality of Life in Premenopausal Women
ClinicalTrials.gov study NCT00084344. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Sex Steroids Balance for Metabolic and Reproductive Health in Klinefelter Syndrome
ClinicalTrials.gov study NCT05586802. IPD Sharing: YES. Countries: 1. Publications: 0.
Sex Differences in Response to Plasmodium chabaudi Infection: Involvement of Gonadal Steroids
GEO Series GSE4324. Mus musculus. 48 samples. Type: Expression profiling by array.
Reciprocal Influence of Sex Steroid Environment and Adipocyte Function in Men
ClinicalTrials.gov study NCT00740194. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Sex Steroid Hormones and Risk of CHD in Women
ClinicalTrials.gov study NCT00006407. IPD Sharing: Not stated. Countries: 0. Publications: 0.
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Allen Brain Atlas
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Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
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