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datasets available to search
ShareScore release 0.9.0
Dataset results
66 results for “subthalamic nucleus”
Combined Subthalamic and Nucleus Basalis Meynert Deep Brain Stimulation for Parkinson's Disease With Dementia
ClinicalTrials.gov study NCT02589925. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Subthalamic Nucleus Deep Brain Stimulation in Speech Study
ClinicalTrials.gov study NCT05493670. IPD Sharing: NO. Countries: 1. Publications: 11.
New Approaches in MRI at 3T Dedicated to Targeting Subthalamic Nucleus on Parkinsonian Patients
ClinicalTrials.gov study NCT02800460. IPD Sharing: NO. Countries: 1. Publications: 14.
Data from: Mapping movement, mood, motivation, and mentation in the subthalamic nucleus
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Therapeutic Deep Brain Stimulation Disrupts Subthalamic Nucleus Activity Dynamics in Parkinsonian Mice
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Data from: Local fields in human subthalamic nucleus track the lead-up to impulsive choices
The ability to adaptively minimize not only motor but cognitive symptoms of neurological diseases, such as Parkinson's Disease (PD) and obsessive-compulsive disorder (OCD), is a primary goal of next-generation deep brain stimulation (DBS) devices. On the basis of studies demonstrating a link between beta-band synchronization and severity of motor symptoms in PD, the minimization of beta band activity has been proposed as a potential training target for closed-loop DBS. At present, no comparable signal is known for the impulsive side effects of PD, though multiple studies have implicated theta band activity within the subthalamic nucleus (STN), the site of DBS treatment, in processes of conflict monitoring and countermanding. Here, we address this challenge by recording from multiple independent channels within the STN in a self-paced decision task to test whether these signals carry information sufficient to predict stopping behavior on a trial-by-trial basis. As in previous studies, we found that local field potentials (LFPs) exhibited modulations preceding self-initiated movements, with power ramping across multiple frequencies during the deliberation period. In addition, signals showed phasic changes in power around the time of decision. However, a prospective model that attempted to use these signals to predict decision times showed effects of risk level did not improve with the addition of LFPs as regressors. These findings suggest information tracking the lead-up to impulsive choices is distributed across multiple frequency scales in STN, though current techniques may not possess sufficient signal-to-noise ratios to predict—and thus curb—impulsive behavior on a moment-to-moment basis.
Subthalamic Nucleus (STN) Targeted Transcranial Temporal Interference Stimulation (TIS) Treats Parkinson's Disease
ClinicalTrials.gov study NCT07361250. IPD Sharing: NO. Countries: 0. Publications: 3.
Low Frequency Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease
ClinicalTrials.gov study NCT03204526. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Burst-Type Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease
ClinicalTrials.gov study NCT05753449. IPD Sharing: NO. Countries: 1. Publications: 0.
Deep Brain Stimulation of the Subthalamic Nucleus (STN) and Cognitive Control
ClinicalTrials.gov study NCT00917722. IPD Sharing: NO. Countries: 1. Publications: 0.
Computational Modeling of 60 Hz Subthalamic Nucleus Deep Brain Stimulation for Gait Disorder in Parkinson's Disease
ClinicalTrials.gov study NCT04184791. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Local fields in human subthalamic nucleus track the lead-up to impulsive choices
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L-dopa Versus Dopamine Agonists After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease
ClinicalTrials.gov study NCT02347059. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Subthalamic Nucleus, Akinesia and Parkinson's Disease
ClinicalTrials.gov study NCT01682668. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Constant Current Versus Constant Voltage Subthalamic Nucleus Deep Brain Stimulation in Patients with Parkinson's Disease
ClinicalTrials.gov study NCT06742450. IPD Sharing: YES. Countries: 1. Publications: 0.
Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Disease
ClinicalTrials.gov study NCT07022522. IPD Sharing: NO. Countries: 1. Publications: 0.
Local Fields Potentientals of the Subthalamic Nucleus in Patients With Parkinson's Disease
ClinicalTrials.gov study NCT05820425. IPD Sharing: NO. Countries: 1. Publications: 0.
Mapping Mood in the Subthalamic Nucleus in Parkinson's Disease (PD)
ClinicalTrials.gov study NCT00847431. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Evaluation of the Safety and Efficacy of Bilateral Subthalamic Nucleus (SNT) Radiosurgery in Idiopathic Severe Parkinson's Disease Fulfilling Inclusion Criteria for STN Deep Brain Stimulation and Pres
ClinicalTrials.gov study NCT01284699. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease
ClinicalTrials.gov study NCT06909045. IPD Sharing: YES. Countries: 2. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.