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datasets available to search
ShareScore release 0.9.0
Dataset results
72 results for “toxicity assessment”
Geriatric Assessment in Predicting Chemotherapy Toxicity and Vulnerabilities in Older Patients With Cancer
ClinicalTrials.gov study NCT02517034. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Clinical Trial to Assess the Efficacy and Toxicity of Induction and Consolidation With CPX-351 for Patients Aged 60 to 75 Years With Secondary or High-risk Acute Myeloid Leukemia
ClinicalTrials.gov study NCT04230239. IPD Sharing: NO. Countries: 1. Publications: 14.
Assessment of Nerve Damage Biomarkers in Acute and Chronic Organophosphate Toxicity
ClinicalTrials.gov study NCT06021262. IPD Sharing: Not stated. Countries: 1. Publications: 9.
Advancing systemic toxicity risk assessment: Evaluation of a NAM-based toolbox approach
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Data from: Automated morphological feature assessment for zebrafish embryo developmental toxicity screens
Detection of developmental phenotypes in zebrafish embryos typically involves a visual assessment and scoring of morphological features by an individual researcher. Subjective scoring could impact results and be of particular concern when phenotypic effect patterns are also used as a diagnostic tool to classify compounds. Here we introduce a quantitative morphometric approach based on image analysis of zebrafish embryos. A software called FishInspector was developed to detect morphological features from images collected using an automated system to position zebrafish embryos. The analysis was verified and compared with visual assessments of three participating laboratories using three known developmental toxicants (methotrexate, dexamethasone and topiramate) and two negative compounds (loratadine and glibenclamide). The quantitative approach exhibited higher sensitivity and made it possible to compare patterns of effects with the potential to establish a grouping and classification of developmental toxicants. Our approach improves the robustness of phenotype scoring and reliability of assay performance and, hence, is anticipated to improve the predictivity of developmental toxicity screening using the zebrafish embryo.
Figure 2 in Bio-efficacy of iron and zinc fortified wheat flour along with bio-assessment of its hepatic and renal toxic potential
Figure 2. Microscopic morphology of representative kidney tissues under the effect of varied iron and zinc supplementation in fortified wheat flour (100X; magnification). (A) Normal, no tissue changes seen = 0, (B) peritubular congestion is seen=1.
Validation of the PROFFIT questionnaire to assess financial toxicity in Italian cancer patients. A cross-sectional study.
<p>Data for validation analysis of the PROFFIT instrument to measure financial toxicity of cancer</p>
Assessing the Potential for Reduced Toxicity Using Focal Brachytherapy in Early Stage, Low Volume Prostate Cancer
ClinicalTrials.gov study NCT01354951. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy
ClinicalTrials.gov study NCT01624220. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Wearable Technology and Machine Learning for Early Detection and Risk Assessment of Unacceptable Toxicities in a Paediatric Oncology Cohort
ClinicalTrials.gov study NCT07030998. IPD Sharing: YES. Countries: 1. Publications: 0.
A Clinical Trial to Assess the Effectiveness of NRF2 Activator (Oral Sodium-copper- Chlophyllin ) in Locally Advanced Cervical Cancer to Reduce Late Radiotherapy Toxicity.
ClinicalTrials.gov study NCT07164534. IPD Sharing: UNDECIDED. Countries: 0. Publications: 36.
Data from: Automated morphological feature assessment for zebrafish embryo developmental toxicity screens
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Assessment of wood smoke induced pulmonary toxicity using bronchial, chronic bronchitis-like, and alveolar lung mucosa models at air-liquid interface
GEO Series GSE236857. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing.
High-Throughput Transcriptomics Toxicity Assessment of Eleven Data-Poor Bisphenol A Alternatives
GEO Series GSE271332. Homo sapiens. 286 samples. Type: Expression profiling by high throughput sequencing.
A rapid assessment model for liver toxicity of macrolides and an integrative evaluation for azithromycin impurities
GEO Series GSE195903. Danio rerio. 9 samples. Type: Expression profiling by high throughput sequencing.
Assessment of unique behavioral, morphological, and molecular alterations in the comparative developmental toxicity profiles of PFHxA using the zebrafish model system
GEO Series GSE211171. Danio rerio. 16 samples. Type: Expression profiling by array.
Ecotoxicogenomic assessment of diclofenac toxicity in soil
GEO Series GSE59589. Folsomia candida. 8 samples. Type: Expression profiling by array.
Assessing the toxicity of 17α-ethinylestradiol in rainbow trout using a four-day transcriptomics benchmark dose (BMD) embryo assay
GEO Series GSE171788. Oncorhynchus mykiss. 18 samples. Type: Expression profiling by high throughput sequencing.
Assessment of unique behavioral, morphological, and molecular alterations in the comparative developmental toxicity profiles of PFOA using the zebrafish model system
GEO Series GSE211169. Danio rerio. 16 samples. Type: Expression profiling by array.
A preclinical platform for assessing anti-tumor effects and systemic toxicities of cancer drug targets
GEO Series GSE196783. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.