Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
219
datasets available to search
ShareScore release 0.9.0
Dataset results
219 results for “treatment selection”
Selectivity improvement of polysulfone-zeolite templated carbon membrane by annealing and coating treatment for CO2/CH4 and H2/CH4 separation
Open the record for dataset details and reuse information.
Performance of virtual screening against GPCR homology models: Impact of template selection and treatment of binding site plasticity
Open the record for dataset details and reuse information.
DATASET: Using a Bacterial Protein to Selectively Target Bacterial Biofilms: Treatment of S. epidermidis Biofilms with Targeted Photothermal Gold Nanoparticles
<p>Supporting data for the manuscript.</p>
Data from: Wound treatment and selective help in a termite-hunting ant.
Open wounds are a major health risk in animals, with species prone to injuries likely developing means to reduce these risks. We therefore analysed the behavioural response towards open wounds on the social and individual level in the termite group-hunting ant Megaponera analis. During termite raids some ants get injured by termite soldiers (biting off extremities), after the fight injured ants get carried back to the nest by nestmates. We observed treatment of the injury by nestmates inside the nest through intense allogrooming at the wound. Lack of treatment increased mortality from 10% to 80% within 24 hours, most likely due to infections. Wound clotting occurred extraordinarily fast in untreated injured individuals, within ten minutes. Furthermore, heavily injured ants (loss of five extremities) were not rescued or treated; this was regulated not by the helper but by the unresponsiveness of the injured ant. Interestingly, lightly injured ants behaved "more injured" near nestmates. We show organized social wound treatment in insects through a multifaceted help system focused on injured individuals. This was not only limited to selective rescuing of lightly injured individuals by carrying them back (thus reducing predation risk), but moreover included a differentiated treatment inside the nest.
Selective control of transposable element expression during T cell exhaustion and anti-PD1 treatment
<p>Supplementary data from (Bonté et al.) which contains Human and Mouse RNA-seq data including : </p> <ul> <li><strong>Raw counts and TPM/FPKM expression matrices of data analyzed </strong>(genes, individual TEs, TE subfamilies) <ul> <li>raw.counts / fpkm.count / tpm.counts rds files</li> </ul> </li> <li><strong>SQuiRE raw output files </strong> <ul> <li>SQuiRE.results rds files</li> </ul> </li> <li><strong>Seurat processed single cell object</strong> (with genes, TEs, Subfamilies) <ul> <li>SC.object rds files</li> </ul> </li> </ul> <p>In details, Mouse and Human data are labelled as follows :</p> <ul> <li><strong>Mouse.SC :</strong> <ul> <li><strong>Type of data</strong> : Single cell RNA-seq data of sorted CD8+ TILs (model B16 melanoma tumors )</li> <li><strong>Label of samples </strong>: Naïve like, Early activated, EffectorMemory, Tpex, Tex</li> <li><strong>Origin of the data</strong> : S. J. Carmona, I. Siddiqui, M. Bilous, W. Held, D. Gfeller, Deciphering the transcriptomic landscape of tumor-infiltrating CD8 lymphocytes in B16 melanoma tumors with single-cell RNA-Seq. Oncoimmunology 9, 1737369 (2020).</li> </ul> </li> <li><strong>Mouse.tumor.TILs :</strong> <ul> <li><strong>Type of data</strong> : bulk RNA-seq data of sorted CD8+ TILs (model B16 melanoma tumors)</li> <li><strong>Label of samples </strong>: Tumor Slamf6+ or Tumor Tim3+</li> <li><strong>Origin of the data</strong> : B. C. Miller<em> et al.</em>, Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. <em>Nature Immunology</em> <strong>20</strong>, 326-336 (2019).</li> </ul> </li> <li><strong>Mouse.LCMV.TILs :</strong> <ul> <li><strong>Type of data</strong> : bulk RNA-seq data of sorted CD8+ TILs (model LCMV clone 13)</li> <li><strong>Label of samples </strong>: LCMV Slamf6+ or LCMV Tim3+</li> <li><strong>Origin of the data</strong> : B. C. Miller<em> et al.</em>, Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade. <em>Nature Immunology</em> <strong>20</strong>, 326-336 (2019).</li> </ul> </li> <li><strong>Mouse.LCMV_Fli1.TILs :</strong> <ul> <li><strong>Type of data</strong> : bulk RNA-seq data of sorted CD8+ TILs (model LCMV clone 13)</li> <li><strong>Label of samples </strong>: WT or Fli1KO</li> <li><strong>Origin of the data</strong> : Z. Chen<em> et al.</em>, In vivo CD8(+) T cell CRISPR screening reveals control by Fli1 in infection and cancer. <em>Cell</em> <strong>184</strong>, 1262-1280 e1222 (2021).</li> </ul> </li> <li><strong>Human.TILs </strong>: <ul> <li><strong>Type of data</strong> : bulk RNA-seq data of sorted CD8+ TILs (NSCLC tumor tissue )</li> <li><strong>Label of samples </strong>: Tex or Tpex</li> <li><strong>Origin of the data</strong> : Bonté et al. (ongoing submission)</li> </ul> </li> </ul> <p> </p> <p>Type of features is labeled as follows:</p> <ul> <li><strong>Gene expression</strong> : genes</li> <li><strong>Individual TE expression</strong> : TEs</li> <li><strong>TE subfamiliy expression</strong> : SF</li> </ul> <p>Metadata corresponding to each expression matrix can be found <a href="https://github.com/pebonte/TE_TILs">here</a>.</p> <p> </p>
Fig. 4 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 4. The effect of ozone treatment on the antiradical activity (A) and H2O2 level (B) in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the t-Tukey test (p> 0.05). On the figure: ns - not significant.
Fig. 3 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 3. The effect of ozone treatment ATP level (A) and SDH activity in mitochondria (B) in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the t-Tukey test (p> 0.05). On the figure: ns - not significant.
Fig. 1 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 1. The effect of ozone treatment on the glutathione (GSH) level in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the t-Tukey test (p> 0.05). On the figure: ns - not significant.
Fig. 2 in Effect of ozone treatment on glutathione (GSH) status in selected berry fruit
Fig. 2. The effect of ozone treatment on the activity of glutathione synthetase (A), glutathione reductase (B) and glutathione peroxidase (C) in selected berries. Mean values (n = 18) with standard deviation (error bars) with *, **, *** are statistically different from the respective control at p <0.05, p <0.01, and p <0.001, respectively (one-way ANOVA, Tukey test). Mean values with the same lower (control fruit) or upper (ozonated fruit) case are not statistically significant according to the Tukey test (p> 0.05). On the figure: ns - not significant.
Safety Assessment of One-hour Infusions of SNS-032 for the Treatment of Select Advanced Solid Tumors
ClinicalTrials.gov study NCT00292864. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Study Evaluating the Treatment Selection and Outcome When Changing Antipsychotic Treatment in Schizophrenic Patients
ClinicalTrials.gov study NCT00999895. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of 3 Months of Selective Serotonin Reuptake Inhibitor (SSRI)-Treatment on Metabolism and Hypothalamic-pituitary-adrenal (HPA)-Axis in Young Men Born With Low Birth Weight
ClinicalTrials.gov study NCT00971815. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Selective Internal Radiotherapy (SIRT) Versus Transarterial Chemoembolisation (TACE) for the Treatment of Cholangiocellular Carcinoma (CCC).
ClinicalTrials.gov study NCT01798147. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Selective Axillary Lymph Node Dissection Vs Complete Axillary Dissection: A Randomised Clinical Trial to Assess the Prevention of Lymphedema in Breast Cancer Treatment
ClinicalTrials.gov study NCT03083314. IPD Sharing: NO. Countries: 1. Publications: 7.
The Usefulness of the New EHS/AHS Classification of Primary Umbilical Hernias in the Selection of Method of Their Treatment
ClinicalTrials.gov study NCT06530420. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Randomised Controlled Treatment Study of Selective Mutism
ClinicalTrials.gov study NCT01002196. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Treatment of Avatrombopag for Thrombocytopenia in Patients Undergoing Selective Resection of Hepatocellular Carcinoma
ClinicalTrials.gov study NCT05087459. IPD Sharing: NO. Countries: 1. Publications: 2.
Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial
ClinicalTrials.gov study NCT04300920. IPD Sharing: YES. Countries: 1. Publications: 1.
Optimizing Patient's Selection for Endovascular Treatment in Acute Ischemic Stroke
ClinicalTrials.gov study NCT02446587. IPD Sharing: Not stated. Countries: 1. Publications: 6.
CBT Versus Selective Serotonin Reuptake Inhibitor For Treatment Of Depression In Temporal Lobe Epilepsy Patients
ClinicalTrials.gov study NCT02262156. IPD Sharing: Not stated. Countries: 1. Publications: 1.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.