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162
datasets available to search
ShareScore release 0.9.0
Dataset results
162 results for “urea”
Chronic Liver Disease in Urea Cycle Disorders
ClinicalTrials.gov study NCT03721367. IPD Sharing: NO. Countries: 1. Publications: 2.
Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders (UCDs)
ClinicalTrials.gov study NCT01347073. IPD Sharing: YES. Countries: 1. Publications: 2.
Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder
ClinicalTrials.gov study NCT00345605. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Urea for Chronic Hyponatremia
ClinicalTrials.gov study NCT04588207. IPD Sharing: YES. Countries: 1. Publications: 41.
Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders
ClinicalTrials.gov study NCT00992459. IPD Sharing: YES. Countries: 2. Publications: 2.
Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders
ClinicalTrials.gov study NCT00551200. IPD Sharing: YES. Countries: 1. Publications: 4.
Neurologic Injuries in Adults With Urea Cycle Disorders
ClinicalTrials.gov study NCT00472732. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Data from: Towards sustainable urea electrooxidation: A thermodynamic and green chemistry evaluation of alternative pathways
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Early onset of urea synthesis and ammonia detoxification pathways in three terrestrially developing frogs
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Ammonia oxidation and urea oxidation in Chesapeake Bay and in the global ocean
<p>Two datasets are included in this submission. One dataset contains newly meausured ammonia oxidation, urea oxidation, nitrous oxide production from ammonium and urea in Chesapeake Bay, one of the largest estuaries in the world. The other dataset contains compiled observations of ammonia oxidation, urea oxidation, qPCR analysis of amoA and ureC gene abundance in the global ocean from previous studies. </p> <p><span>Tang, W.</span>, <span>C. Hexter</span>, <span>R. Dai</span>, et al. <span>2025</span>. “ <span>Substrate Effect on the Contribution of Ammonium and Urea to Marine Nitrification and Nitrous Oxide Production</span>.” <em>Environmental Microbiology</em> <span>27</span>, no. <span>10</span>: e70187. <a href="https://doi.org/10.1111/1462-2920.70187">https://doi.org/10.1111/1462-2920.70187</a>.</p>
Ammonia emissions from urea fertilization – multi-annual micrometeorological measurements across Germany [Dataset]
<p>To evaluate the accuracy of the current emission factor (EF) for conventional urea in Germany, ammonia (NH₃) emissions were measured using the integrated horizontal flux (IHF) method with ALPHA passive samplers following urea applications in 2021–2023. Measurements were conducted across six agroecological regions under winter wheat cropping, with nitrogen application rates of 145–230 kg N ha⁻¹, resulting in 51 campaigns.</p> <p>Emission rates (NH₃Ninput) ranged from 1.1% to 20.7% (median 4.8%, mean 8.5%), significantly lower than the 2019 IPCC (14.2%) and 2023 EMEP (16.1% for pH < 7) estimates. NH₃Ninput was influenced by soil texture and rainfall but not nitrogen application rates, with higher emissions observed on sandy soils.</p> <p>These findings suggest current EFs overestimate NH₃ emissions from urea applied to winter wheat in Germany. While emissions may vary due to inter-annual and environmental factors, a national EF for Germany could improve NH₃ emission estimates and the evaluation of mitigation strategies.</p>
Preparation of the synthesis of 1,3 bis(p-Hydroxyphenyl) urea
<p>Preparation of the synthesis of 1,3 bis(p-Hydroxyphenyl) urea</p>
Data for: Reproductive colonization of land by frogs: Embryos and larvae excrete urea to avoid ammonia toxicity
<p>Vertebrate colonization of land occurred multiple times, including over 50 origins of terrestrial eggs in frogs. Some environmental factors and phenotypic responses that facilitated these transitions are known, but responses to water constraints and risk of ammonia toxicity during early development are poorly understood. We tested if ammonia accumulation and dehydration risk induce a shift from ammonia to urea excretion during in early stages of four anurans, from three origins of terrestrial development. We quantified ammonia and urea concentrations during early development on land, under well-hydrated and dry conditions. Where we found urea excretion, we tested for a plastic increase under dry conditions and with ammonia accumulation in developmental environments. We assessed the potential adaptive role of urea excretion by comparing ammonia tolerance measured in 96h-LC<sub>50</sub> tests with ammonia levels in developmental environments. Ammonia accumulated in foam nests and perivitelline fluid, increasing over development and reaching higher concentrations under dry conditions. All four species showed high ammonia tolerance, compared to fishes and aquatic-breeding frogs. Both nest-dwelling larvae of <em>Leptodactylus fragilis</em> and late embryos of <em>Hyalinobatrachium fleischmanni</em> excreted urea, showing a plastic increase under dry conditions. These two species can develop the longest on land and urea excretion appears adaptive, preventing their exposure to potentially lethal levels of ammonia. Neither late embryos of <em>Agalychnis callidryas</em> nor nest-dwelling larvae of <em>Engystomops pustulosus</em> experienced toxic ammonia levels under dry conditions, and neither excreted urea. Our results suggests that an early onset of urea excretion, its increase under dry conditions, and elevated ammonia tolerance, can all help prevent ammonia toxicity during terrestrial development. High ammonia represents a general risk for development which may be exacerbated as climate change increases dehydration risk for terrestrial-breeding frogs. It may also be a cue that elicits adaptive physiological responses during early development.</p>
Wan et al._N2O production during urea oxidation by AOM
<p>Dataset for the manuscript '<strong>Large N<sub>2</sub>O source due to preferential use of urea by ammonia oxidizing bacteria</strong>'</p>
Dataset_urea oxidaiton in the oligotrophic ocean
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Increasing the sensitivity of hyperpolarized [15N2]urea detection by serial transfer of polarization to spin-coupled protons
<p>This upload contains the raw data, MATLAB scripts and Mathematica notebooks used for the publication.</p> <p>Figure 2, 3, 7 and 8 where generated with the Mathematica notebooks in the folder Mathematica_Notebooks.</p> <p>Figure 4 was generated with the raw data in NOE_data/20190821 and processed with the script NOE_data/20190821/H1to15NNOEin15N2urea.m</p> <p>Figure 5a is based on data in Polarization_Transfer_Data/spectral/timecourse/_fk_BHINDER_flipback_15Nto1H_hyp_20180609_01.fid processed with Polarization_Transfer_Data/spectral/timecourse/_fk_BHINDER_flipback_15Nto1H_hyp_20180609_01.fid/timecourse.m</p> <p>Figure 5b is based on Polarization_Transfer_Data/imaging/_fk_BHINDER_flipback_EPIP_hyp_10perc_20180531_01.img . From this raw data image2 - image60 are acquired after polarisation transfer. Image1 is a direct acquisition of the water resonance .</p> <p>The brightness and contrast of the images was adjusted and a montage of images 2 to 9 was created with (Fiji <a href="https://imagej.net/software/fiji/">https://imagej.net/software/fiji/</a>) .</p> <p>Figure 6 is based on data in Polarization_Transfer_Data/spectral/interleaved processed with Polarization_Transfer_Data/spectral/interleaved/comparision.m</p> <p>The script Pulse_Generation/createIRRUPT.m was used to generate the adiabatic pulses.</p>
Indirect Calorimetry Versus Urea-creatinine Ratio to Evaluate Catabolism in Critically Ill Patients
ClinicalTrials.gov study NCT06244381. IPD Sharing: NO. Countries: 1. Publications: 6.
A Study Of BRL49653C For The Treatment Of Type 2 Diabetes (Combination Therapy With Sulfonyl Urea) -With Placebo Study
ClinicalTrials.gov study NCT00432679. IPD Sharing: NO. Countries: 1. Publications: 0.
Continuous Veno-venous Hemodialysis and Continuous Veno-venous Hemodiafiltration on Urea Reduction Rate in Intensive Care Patient
ClinicalTrials.gov study NCT06369064. IPD Sharing: Not stated. Countries: 1. Publications: 5.
Urea Cream Prevention for Capecitabine Associated Hand Foot Syndrome
ClinicalTrials.gov study NCT05348278. IPD Sharing: NO. Countries: 1. Publications: 1.
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Allen Brain Atlas
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