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4,563 results for “Correlation”
Candidate genes correlated with progression to androgen-resistant stage in the LuCaP 23.1 xenograft model.
GEO Series GSE6284. Mus musculus; Homo sapiens. 3 samples. Type: Expression profiling by array.
Correlating citric acid formation and manganese limitation in Aspergillus niger using transcriptome and proteome analysis
GEO Series GSE61985. Aspergillus oryzae; Aspergillus niger; Aspergillus nidulans. 9 samples. Type: Expression profiling by array.
Gene expression of lipid metabolism-related genes correlated with milk fatty acids in dairy cows
GEO Series GSE20908. Bos taurus. 56 samples. Type: Expression profiling by array.
Data set from the article Vianello E, Marrocco-Trischitta Massimiliano M, Dozio E, Bandera F, Tacchini L, Canciani E, Dellavia C, Schmitz G, Lorenzo M, Corsi Romanelli Massimiliano M. Correlational study on altered epicardial adipose tissue as a stratification risk factor for valve disease progression through IL-13 signaling. J Mol Cell Cardiol. 2019 Jul;132:210-218. doi: 10.1016/j.yjmcc.2019.05.012. Epub 2019 May 15. Erratum in: J Mol Cell Cardiol. 2019 Aug;133:112. PMID: 31102584.
<p>Data set from the article Vianello E, Marrocco-Trischitta Massimiliano M, Dozio E, Bandera F, Tacchini L, Canciani E, Dellavia C, Schmitz G, Lorenzo M, Corsi Romanelli Massimiliano M. Correlational study on altered epicardial adipose tissue as a stratification risk factor for valve disease progression through IL-13 signaling. J Mol Cell Cardiol. 2019 Jul;132:210-218. doi: 10.1016/j.yjmcc.2019.05.012. Epub 2019 May 15. Erratum in: J Mol Cell Cardiol. 2019 Aug;133:112. PMID: 31102584.</p> <p>This is the abstract:</p> <p><strong>Aims: </strong>Genetic and environmental factors all interact in the risk of progression of valvular dysfunctions. Previous studies reported a relation between valve diseases and epicardial adipose tissue (EAT) thickness. The aim of this study was to verify the possible relationship between the molecular pattern of EAT related to IL-13 fibrogenic cytokine expression and valve dysfunction.</p> <p><strong>Methods and results: </strong>A valvular heart disease (VHD) population was stratified according to their median EAT thickness (7 mm). The molecular expression of IL-13 in EAT is directly related to the molecular expression of genes associated with extracellular matrix (ECM) turnover, macrophage infiltration and promotion of the formation of ectopic calcific nodules involved in aorta coarctation and calcification.</p> <p><strong>Conclusion: </strong>IL-13 gene expression in altered EAT is directly related to the expression of genes involved in ECM turnover and the formation of ectopic calcific nodules, suggesting measurements of EAT as a stratification risk factor for valve instability in the VHD patients.</p> <p> </p>
Mortality in an Italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementation, and limitations of the diagnostic tests
<p><strong>Introduction: </strong> The COVID-19 pandemic caused an increased mortality in nursing homes due to its quick spread and the age-related high lethality.</p> <p><strong>Results: </strong> We observed a two-month mortality of 40%, compared to 6.4% in the previous year. This increase was seen in both COVID-19 positive (43%) and negative (24%) residents, but 8 patients among those testing negative on the swab, tested positive on serological tests. Increased mortality was associated with male gender, older age, no previous vitamin D supplementation and worse "activities of daily living (ADL)" scores, such as Barthel index, Tinetti scale and S.OS.I.A.</p> <p><strong>Conclusion: </strong> Our data confirms a higher geriatric mortality due to COVID-19. Negative residents also had higher mortality, which we suspect is secondary to preanalytical error and a low sensitivity of the swab test in poorly compliant subjects. Male gender, older age and low scores on ADL scales (probably due to immobility) are risk factors for COVID-19 related mortality. Finally, mortality was inversely associated with vitamin D supplementation.</p> <p><strong>Design: </strong> In this observational study, we described the two-month mortality among the 157 residents (age 60-100) of a nursing home after Sars-CoV-2 spreading, reporting the factors associated with the outcome. We also compared the diagnostic tests for Sars-CoV-2.</p> <p> </p><p>https://pubmed.ncbi.nlm.nih.gov/33353888/</p> <p></p>
Dataset related to article "Imaging Correlates between Headache and Breast Cancer: An [18F]FDG PET Study"
<p>This record contains raw data related to article "Imaging Correlates between Headache and Breast Cancer: An [18F]FDG PET Study"</p><p><strong>Abstract</strong></p><p>This study aimed to examine brain metabolic patterns on [18F]Fluorodeoxyglucose ([18F]FDG) positron emission tomography (PET) in breast cancer (BC), comparing patients with tension-type headache (TTH), migraine (MiG), and those without headache. Further association with BC response to neoadjuvant chemotherapy (NAC) was explored. In this prospective study, BC patients eligible for NAC performed total-body [18F]FDG PET/CT with a dedicated brain scan. A voxel-wise analysis (two-sample <i>t</i>-test) and a multiple regression model were used to compare brain metabolic patterns among TTH, MiG, and no-headache patients and to correlate them with clinical covariates. A single-subject analysis compared each patient's brain uptake before and after NAC with a healthy control group. Primary headache was diagnosed in 39/46 of BC patients (39% TTH and 46% MiG). TTH patients exhibited hypometabolism in specific brain regions before NAC. TTH patients with a pathological complete response (pCR) to NAC showed hypermetabolic brain regions in the anterior medial frontal cortex. The correlation between tumor uptake and brain metabolism varied before and after NAC, suggesting an inverse relationship. Additionally, the single-subject analysis revealed that hypometabolic brain regions were not present after NAC. Primary headache, especially MiG, was associated with a better response to NAC. These findings suggest complex interactions between BC, headache, and hormonal status, warranting further investigation in larger prospective cohorts.</p>
Dataset to submitted manuscript "Exploring Nanofibrous Networks with X-ray Photon Correlation Spectroscopy"
<p><strong>This zip-archive contains all raw data and processing scripts used to produce the results presented in the manuscript</strong><strong> entitled:</strong></p> <p><strong><em>"Exploring Nanofibrous Networks with X-ray Photon Correlation Spectroscopy"</em></strong></p>
Cardiac tumors: imaging findings, clinical correlations and surgical treatment in a 15 years single-center experience
<p>This record contains raw data related to the article “Cardiac tumors: imaging findings, clinical correlations and surgical treatment in a 15 years single-center experience”<br> </p> <p>Abstract</p> <p><strong>Background: </strong>We aimed to: present the clinical and pathological characteristics of cardiac tumors in a single-center series of patients, describe the association of imaging characteristics, clinical presentation and surgical treatment, analyze if second level imaging tests, computed tomography (CT) and cardiac magnentic resonance (CMR), improve the diagnostic accuracy when compared to first-line imaging technique (transthoracic echocardiography,TTE).</p> <p><strong>Methods: </strong>We reviewed the medical and surgical records, TTE, CT and CMR examinations of 86 patients with an histological diagnosis of cardiac tumors between 2004 and 2019.</p> <p><strong>Results: </strong>The majority were benign tumors (81%) with myxoma accounting for 66% of cases. Among malignancies, metastasis (8%) and primary tumors (10%) were equally recognized. Symptoms at presentation (45% of patients) were associated to larger diameters at TTE. Malignancies were larger (mean diameter 37±14 mm vs 27±13 mm, p<0.01), more frequently exhibited irregular shape (67% vs 17%, p<0.01), frayed or polylobulated surface (73% vs 38%, p=0.035), heterogeneous aspect (67% vs 32%, p=0.012). A maximum diameter >28mm and a minimum diameter >19.5mm emerged as possible cut-off values for the differentiation of benign and malignant tumors. The ability of TTE, CT and CMR features in identifying malingnancies was moderate (diagnostic accuracy of 84%, 81%, 76% respectively). The mean survival time after surgery was 1.6±1.4 years in malignancies and 6.8±4.7 years in benign tumors.</p> <p><strong>Conclusions: </strong>Cardiac tumors are rare and mostly benign; their nature and clinics related to TTE appearance. CT and CMR may be used sinergically with TTE. Surgery is curative in benign tumors, survival remains scarce in malignancies.</p>
Subcutaneous, Paracardiac, and Epicardial Fat CT Density Before/After Contrast Injection: Any Correlation with CAD?
<p>Dataset from Monti CB, Capra D, Malavazos A, Florini G, Parietti C, Schiaffino S, Sardanelli F, Secchi F. Subcutaneous, Paracardiac, and Epicardial Fat CT Density Before/After Contrast Injection: Any Correlation with CAD? J Clin Med. 2021 Feb 12;10(4):735. doi: 10.3390/jcm10040735. PMID: 33673256; PMCID: PMC7918165.</p> <p>Abstract</p> <p>Adipose tissue, in particular epicardial adipose tissue, has been identified as a potential biomarker of cardiovascular pathologies such as coronary artery disease (CAD) in the light of its metabolic activity and close anatomic and pathophysiologic relationship to the heart. Our purpose was to evaluate epicardial adipose tissue density at both unenhanced and contrast-enhanced computed tomography (CT), along with CT densities of paracardiac and subcutaneous adipose tissue, as well as the relations of such densities with CAD. We retrospectively reviewed patients who underwent cardiac CT at our institution for CAD assessment. We segmented regions of interest on epicardial, paracardiac, and subcutaneous adipose tissue on unenhanced and contrast-enhanced scans. A total of 480 patients were included, 164 of them presenting with CAD. Median epicardial adipose tissue density measured on contrast-enhanced scans (-81.5 HU; interquartile range -84.9 to -78.0) was higher than that measured on unenhanced scans (-73.4 HU; -76.9 to -69.4) (<em>p</em> < 0.001), whereas paracardiac and subcutaneous adipose tissue densities were not (<em>p</em> ≥ 0.055). Patients with or without CAD, did not show significant differences in density of epicardial, paracardiac, and subcutaneous adipose tissue either on unenhanced or contrast-enhanced scans (<em>p</em> ≥ 0.092). CAD patients may experience different phenomena (inflammation, fibrosis, increase in adipose depots) leading to rises or drops in epicardial adipose tissue density, resulting in variations that are difficult to detect.</p>
dataset related to article "Italian cohort of Lafora disease: Clinical features, disease evolution, and genotype-phenotype correlations"
<p>dataset relateto to article at title</p>
Correlation between the Covalency and the Thermometric Properties of Yb3+/Er3+ Codoped Nanocrystalline Orthophosphates
<p>Lanthanide-doped NaYF4 nanoparticles are most frequently studied host materials for numerous biomedical applications. Although efficient upconversion can be obtained in fluoride nanomaterials and good homogeneity of size and morphology is achieved, they are not very predestined for extensive material optimization toward enhanced features and functions. Here, we study the impact of rare-earth metals RE = Y, Lu, La, and Gd ions within Yb3+/Er3+ codoped nanocrystalline REPO4 orthophosphates. The enhanced luminescent thermometry features were found to be in relation to the covalency of RE3+− O2− bonds being modulated by these optically inactive rare-earth ion substitutes. Up to 30% relative sensitivity enhancement was found (from ca. 3.0 to ca. 3.8%/K at −150 °C) by purposefully increasing the covalence of the RE3+−O2− bond. These studies form the basis for intentional optimization thermal couple-based luminescent thermometers such as Yb3+- Er3+ upconverting ratiometric thermometer.</p>
Incubation temperature affects the expression of young precocial birds' fear-related behaviours and neuroendocrine correlates
<p>Raw datasets used for the article (under review): </p> <p><strong>Incubation temperature affects the expression of young precocial birds’ fear-related behaviours and neuroendocrine correlates </strong></p> <p> </p> <p>Aline Bertin<sup>1</sup>, Ludovic Calandreau<sup>1</sup>, Maryse Meurisse<sup>1</sup>, Marion Georgelin<sup>1</sup>, Rupert Palme<sup>2</sup>, Sophie Lumineau<sup>3</sup>, Cécilia Houdelier<sup>3</sup>, Anne-Sophie Darmaillacq<sup>3</sup>, Ludovic Dickel<sup>3</sup>, Violaine Colson<sup>4</sup>, Fabien Cornilleau<sup>1</sup>, Christophe Rat<sup>5</sup>, Joel Delaveau<sup>5</sup>, Cécile Arnould<sup>1</sup></p> <p> </p> <p><sup>1</sup> PRC, CNRS, IFCE, INRA, Université de Tours, 37380, Nouzilly, France ; <sup>2 </sup>Unit of Physiology, Pathophysiology, and Experimental Endocrinology, Department of Biomedical Sciences, University of Veterinary Medicine, 1210 Vienna, Austria; <sup>3 </sup>UMR CNRS 6552, Ethos, Université de Rennes1, 35042, Rennes, France; <sup>4 </sup>INRA, UR1037 Fish Physiology and Genomics, F-35000 Rennes, France ; <sup>5</sup> UE1295 Pôle d’Expérimentation Avicole de Tours, F-37380 Nouzilly, France</p> <p> </p> <p><em>Correspondence and requests for materials should be addressed to A.B. (e-mail:</em> aline.bertin@inra.fr)</p> <p> </p>
Fine-scale tree spatial patterns are shaped by dispersal limitation which correlates to functional traits in a natural temperate forest - Raw SPPA data
<p>Raw data allowing the reproduction of the spatial point pattern analysis detailed in Beyns, R. et al. (2021) Fine-scale tree spatial patterns are shaped by dispersal limitation which correlates to functional traits in a natural temperate forest. <em>Journal of Vegetation Science</em>.</p>
Lung Ultrasound in Patients With SARS-COV-2 Pneumonia Correlations With Chest Computed Tomography, Respiratory Impairment, and Inflammatory Cascade
<p>Objectives—Lung ultrasound (LUS) might be comparable to chest computed tomography (CT) in detecting parenchymal and pleural pathology, and in monitoring interstitial lung disease. We aimed to describe LUS characteristics of patients during the hospitalization for COVID-19 pneumonia, and to compare the extent of lung involvement at LUS and chest-CT with inflammatory response and the severity of respiration impairment.<br> Methods—During a 2-week period, we performed LUS and chest CT in hospitalized patients affected by COVID-19 pneumonia. Dosages of high sensitivity C-reactive protein (HS-CRP), D-dimer, and interleukin-6 (IL-6) were also obtained. The index of lung function (P/F ratio) was calculated from the blood gas test. LUS and CT scoring were assessed using previously validated scores. <br> Results—Twenty-six consecutive patients (3 women) underwent LUS 34 - 14 days from the early symptoms. Among them, 21 underwent CT on the same day of LUS. A fair association was found between LUS and CT scores (R = 0.45, P = .049), which became stronger if the B-lines score on LUS was not considered (R = 0.57, P = .024). LUS B-lines score correlated with IL-6 levels (R = 0.75, P = 0.011), and the number of involved lung segments detected by LUS correlated with the P/F ratio (R = 0.60, P = .019) but not with HS-CRP and D-Dimer levels. No correlations were found between CT scores and inflammations markers or P/F.<br> Conclusion—In patients with COVID-19 pneumonia, LUS was correlated with both the extent of the inflammatory response and the P/F ratio. </p>
Unconventional spin transport in strongly correlated kagome systems
<p>This dataset contains the code and the data used for the corresponding publication.</p>
Differentially expressed genes in HBV related hepatic disease patients and the correlation with prognosis
GEO Series GSE267808. Homo sapiens. 20 samples. Type: Expression profiling by high throughput sequencing.
Differential gene expression is not correlated to age-related vascular pathology in aorta and mesenteric artery of Brown Norway and Fischer344xBrown Norway rats
GEO Series GSE55612. Rattus norvegicus. 71 samples. Type: Expression profiling by array.
Stress granule-mediated sequestration of EGR1 mRNAs correlates with lomustine-induced cell death prevention
GEO Series GSE269691. Homo sapiens. 24 samples. Type: Expression profiling by array.
DE 1 Plasma Wave Instrument (PWI) Low Frequency Correlator Electric and Magnetic Field Spectral Density
Two Dynamics Explorer (DE) spacecraft were launched August 3, 1981, and placed into coplanar polar orbits with DE-1 in a highly elliptical orbit and DE-2 in a lower more circular orbit. The primary objective of the DE program was to investigate magnetosphere-ionosphere-atmosphere coupling processes. The DE mission provided a wealth of new information on a wide variety of magnetospheric plasma wave phenomena including auroral kilometric radiation, auroral hiss, Z mode radiation, narrow-band electromagnetic emissions associated with equatorial upper hybrid waves, whistler mode emissions, wave-particle interactions stimulated by ground VLF transmitters, equatorial ion cyclotron emissions, ion Bernstein mode emissions, and electric field turbulence along the auroral field lines. These files contain calibrated, full resolution, data from the DE-1 Plasma Wave Instrument (PWI). This instrument was designed and built by the plasma wave group at The University of Iowa, Department of Physics and Astronomy, in collaboration with investigators at Stanford University's STAR Laboratory. It measured plasma wave phenomena and quasi-static electric fields using paired combinations of five PWI sensors: a 200m tip-to-tip long wire electric antenna deployed in the spacecraft spin plane, a 9m tip-to-tip tubular electric antenna deployed along the spacecraft spin axis, a short 0.6m electric antenna, mounted on the boom and oriented parallel to the long wire antenna, a magnetic loop antenna mounted on the boom and oriented to measure the component of the magnetic field parallel to the long wire antenna, and a magnetic search coil antenna, also mounted on a boom and oriented to measure the magnetic field parallel to the spacecraft spin axis. The PWI main electronics unit consisted of a Step Frequency Correlator (SFC), a Low Frequency Correlator (LFC), a Wideband Analog Receiver (WBR) and a Linear Wave Receiver (LWR). Only the LFC data are included in these files. The SFC data were provided in a companion fileset. A dataset containing available high rate WBR LWR data may be provided in future archive products. The LFC consisted of two receivers (LFR-A and LFR-B) with 8 analog channels each. The analog channels were centered at 1.78, 3.12, 5.62, 10.0, 17.8, 31.2, 56.2 and 100 Hz. Each channel's band-edge was at +/-15% of the center value. Each LFR in the LFC could be connected to either the Ex, Es, Ez, or H antenna during an 8 second major frame. In addition, the Low Frequency Correlator provided in-phase and quadrature-phase correlations of signals from any selected antenna pair. Phase data are not provided in this file set.
DE 1 Plasma Wave Instrument (PWI) Step Frequency Correlator Electric and Magnetic Field Spectral Density
Two Dynamics Explorer (DE) spacecraft were launched August 3, 1981, and placed into coplanar polar orbits with DE-1 in a highly elliptical orbit and DE-2 in a lower more circular orbit. The primary objective of the DE program was to investigate magnetosphere-ionosphere-atmosphere coupling processes. The DE mission provided a wealth of new information on a wide variety of magnetospheric plasma wave phenomena including auroral kilometric radiation, auroral hiss, Z mode radiation, narrow-band electromagnetic emissions associated with equatorial upper hybrid waves, whistler mode emissions, wave-particle interactions stimulated by ground VLF transmitters, equatorial ion cyclotron emissions, ion Bernstein mode emissions, and electric field turbulence along the auroral field lines. These files contain calibrated, full resolution, data from the DE-1 Plasma Wave Instrument (PWI). This instrument was designed and built by the plasma wave group at The University of Iowa, Department of Physics and Astronomy, in collaboration with investigators at Stanford University's STAR Laboratory. It measured plasma wave phenomena and quasi-static electric fields using paired combinations of five PWI sensors: a 200m tip-to-tip long wire electric antenna deployed in the spacecraft spin plane, a 9m tip-to-tip tubular electric antenna deployed along the spacecraft spin axis, a short 0.6m electric antenna, mounted on the boom and oriented parallel to the long wire antenna, a magnetic loop antenna mounted on the boom and oriented to measure the component of the magnetic field parallel to the long wire antenna, and a magnetic search coil antenna, also mounted on a boom and oriented to measure the magnetic field parallel to the spacecraft spin axis. The PWI main electronics unit consisted of a Step Frequency Correlator (SFC), a Low Frequency Correlator (LFC), a Wideband Analog Receiver (WBR) and a Linear Wave Receiver (LWR). Only the SFC data are included in these files. The LFC data were provided in a companion fileset. A dataset containing available high rate WBR LWR data may be provided in the future. The SFC consisted of two Step Frequency Receivers (SFR-A and SFR-B) which provided amplitude measurements of the electric and magnetic fields from 100 Hz to 400 kHz and in-phase and quadrature-phase correlations of signals from any selected antenna pair. Phase data are not provided in these datasets.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.