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830 results for “tumor microenvironment”
Data from: Development of an adrenocortical cancer humanized mouse model to characterize anti-PD1 effects on tumor microenvironment
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Data from: Phosphorescence monitoring of hypoxic microenvironment in solid-tumors to evaluate chemotherapeutic effects using the hypoxia-sensitive iridium (III) coordination compound
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Raw and normalized count data for "Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling"
<p>SingleCellExperiment objects containing raw and normalized counts, as well as reduced dimension representations and cell type annotations for both the follicular lymphoma samples (sce_follicular_annotated_final.rds) and high grade serous ovarian cancer samples (sce_hgsc_annotated_final.rds) as detailed in the paper, as well as reactive lymph node data (sce_RLN_normalized.rds).</p>
Characterization of the tumor-immune microenvironment in hepatocellular carcinoma patients undergoing immune checkpoint inhibitor therapy by highly multiplexed imaging mass cytometry
<p>Imaging mass cytometry data of 42 HCC patients that received immune checkpoint inhibtor therapy after tumor biopsy or resection. </p> <ul> <li>ICI_img_normalized: Preprocessed and normalized multistack .tiff images. Each stack represents one channel. Channel annotations are stored in the ICICohort_panel.csv file.</li> <li>ICI_cellmasks: Masks identifying individual cells on the images.</li> <li>ICI_stromamasks: Masks identifying stromal and parenchymal regions on the image.</li> <li>ICICohort_panel.csv: table containing channel information (metal tag and marker).</li> </ul> <p>Patient etadata may be found in the supplementary table 3 of DOI <a href="https://doi.org/10.1136/gutjnl-2024-332837" target="_blank" rel="noopener noreferrer">10.1136/gutjnl-2024-332837</a>.</p>
Increased spatial coupling of integrin and collagen IV in the immunoresistant clear-cell renal-cell carcinoma tumor microenvironment - Validation mIF
<p>mIF object from <em>spatialTIME</em> R package, calculating univariate Ripley's K on multiplex immunofluorescence images stained with FOXP3, CD8, CD68, ITGAV, COL4, VIM, SMA, and PCK. Data was processed with InForm and HALO. </p> <p>Clear cell renal cell carcinoma and papillary renal cell carcinoma were profiled before and after exposure to immunotherapy, with and without sarcomatoid features in clear cell tumors. Each tumor had a field of view in the stromal compartment and field of view in the tumor compartment.</p> <p>For appropriate clinical information associated with this study, please contact Dr. Brandon Manley.</p>
Tumor microenvironment drawing
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Tumor microenvironment drawing
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Spatial profile of tumor microenvironment in PD-L1-negative and PD-L1-positive triple negative breast cancer
<p><strong>Supplementary Materials</strong></p>
Artificial Intelligence-based Tumor Microenvironment Analysis for Prognosis Prediction in Gallbladder Cancer
ClinicalTrials.gov study NCT07092397. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Tumor Microenvironment
ClinicalTrials.gov study NCT05982574. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Effect of Acetylcysteine With Topotecan Hydrochloride on the Tumor Microenvironment in Patients With Persistent or Recurrent High Grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer
ClinicalTrials.gov study NCT02569957. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Data from: Cell shape and the microenvironment regulate nuclear translocation of NF-kappaB in breast epithelial and tumor cells
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Tractable mouse TNBC models capture the heterogeneous tumor immune microenvironment and adaptation to PD-L1 blockade
GEO Series GSE290815. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Inhibition of the chemokine receptors CXCR1 and CXCR2 synergizes with docetaxel for effective tumor control and remodeling of the immune microenvironment of HPV-negative head and neck cancer models [m
GEO Series GSE280355. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.
Characterizing the Tumor Immune Microenvironment of Syngeneic Mouse Models of Ovarian Cancer to Predict Response to PD-L1 blockade
GEO Series GSE183368. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Multi-omic profiling unveils molecular landscapes and heterogeneous tumor microenvironment in sinonasal squamous cell carcinoma
GEO Series GSE278149. Homo sapiens. 40 samples. Type: Methylation profiling by genome tiling array; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling [VisiumHD]
GEO Series GSE280315. Homo sapiens. 5 samples. Type: Other.
A single cell atlas of the human liver tumor microenvironment
GEO Series GSE146409. Homo sapiens. 151 samples. Type: Expression profiling by high throughput sequencing.
Bexmarilimab activates human tumor-associated macrophages to support adaptive immune responses in interferon-poor immune microenvironments
GEO Series GSE222649. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis
GEO Series GSE243280. Homo sapiens. 7 samples. Type: Other; Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.