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10,244 results for “Vaccine”
Fig. 2. Post mortem examination. Post mortem examination for typical calves showing signs associated with Theileria infection. A in Exposure of vaccinated and naive cattle to natural challenge from buffalo-derived Theileria parva
Fig. 2. Post mortem examination. Post mortem examination for typical calves showing signs associated with Theileria infection. A: Copious frothy exudate from nasal cavities of BJ031 and BJ037. B: Pleural exudate in thoracic cavities of BJ033 and BJ041. C: Frothing in trachea of BJ026 and BJ033.
Fig. 1 in Exposure of vaccinated and naive cattle to natural challenge from buffalo-derived Theileria parva
Fig. 1. Kaplan–Meier survival analysis. Kaplan–Meier survival analysis of vaccinated (dashed line) and control (solid line) calves following field exposure. The black circle and red cross at day 30 represent the animals remaining alive at the end of the experiment (censored). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
Vaccination B cell dataset antibodies (DDW lab)
<p>The present vaccination dataset, obtained by the group of Deborah Dunn-Walters in 2012 ("vaccination") contains B cell repertoire data of six young (aged 19-45) and six elderly (aged 70-89) healthy volunteers. Three samples per donor have been taken: The first prior to vaccination (with Influvac and Pneumovax II) called "Day 0", the next seven days later ("Day 7") and the last one 28 days after vaccination ("Day 28"). This allows for a time-resolved monitoring of the immune response for the two different age groups. In total, the data set (as downloaded) contains 45784 observations.</p>
Supplementary data to: Detection of Neoantigen-specific T Cells Following a Personalized Vaccine in a Patient with Glioblastoma
<p>Supplemental Data for the patient described in the manuscript: "Detection of Neoantigen-specific T Cells Following a Personalized Vaccine in a Patient with Glioblastoma". Summary of somatic variant calls from DNA whole exome, gene FPKM from RNA sequencing, and neoantigen predictions for high-affinity (ic<sub>50</sub> <500 nM) candidates.</p>
Fig. 1 in Nasal vaccination of six squirrel monkeys (Saimiri sciureus): Improved immunization protocol against Toxoplasma gondii with a nanoparticle-born vaccine
Fig. 1. Schedule of the vaccinal protocol and of the immunological analysis performed on the 6 Saimiris.
Fig. 2. T in Nasal vaccination of six squirrel monkeys (Saimiri sciureus): Improved immunization protocol against Toxoplasma gondii with a nanoparticle-born vaccine
Fig. 2. T-cell immune response analyzed by IFN-γ ELISPOT on PBMC from 6 Saimiris. The results are presented as Spot Forming Units for 106 PBMC (left), before the immunization (T0), one month after the prime, 5 months after the 1st boost and 2 months after the 2nd boost. A representative picture of the ELISPOT plate after the 2nd boost is presented (right). Only 4 animals were analyzed by ELISPOT after the 2nd boost due to blood coagulation in the sampling tubes. Statistical analyses were made by KruskalWallis test, * p <0.05, ** p <0.01.
Fig. 3 in Nasal vaccination of six squirrel monkeys (Saimiri sciureus): Improved immunization protocol against Toxoplasma gondii with a nanoparticle-born vaccine
Fig. 3. Humoral immune response analyzed by ELISA on serum for each Saimiri. The results are presented as optical density (OD) before the immunization (T0), and 2 months after the 2nd boost. Serum from one seropositive and three seronegative humans were used as positive and negative controls, respectively. Cut-off was determined at each dilution, as the mean + 2.5xSD of the negative controls.
Interferon-induced activation of dendritic cells and monocytes by yellow fever vaccination correlates with early antibody responses
<p>Bulk RNA-seq analysis of sorted subpopulations isolated from PBMC of yellow fever vaccinees from before and 3, 7, 14 and 28 days after vaccination and single cell RNA-seq analysis of sorted DC and monocytes fractions isolated from PBMC of of yellow fever vaccinees from before and 3 and 7 days after vaccination.</p>
Competition between predicting mathematical models and laboratory results for covid 19 after vaccination in Iran
<p>All of us like to find a way to end Covid 19. Specially, economy confronts with many problems. In attached JPG, i bring two predictions for covid 19 pandemic in Iran. Mathematical model predicts that after a fall in figure we will have a peak. However, right now, most of people in Iran used of vaccines. In addition, government forced on all to get vaccine. Even, students with 12 to 18 years old get vaccine. It has been heard that soonly, kids with ages between 3-12 years old will receive vaccine. As a man or woman, all of us like that this program will response and vaccines work. However, predictions of math show reverse result. Although, maybe, we should enter the factor of vaccine in mathematical model. It is good opportunity for scientists to examine response of covid 19 to program of vaccine for all. Even if we have a peak, however its height be smaller, we can say that vaccines act. Hope for ending Covid 19 in all countries.</p>
Spatial analysis of Measles Vaccination Coverage in the State of São Paulo
<p>Dataset for the article Spatial Analysis of Measles Vaccination Coverage in the State of São Paulo. The aim of the present study was to evaluate first and second dose of measles vaccine coverage (VC) in the cities of São Paulo and its spatial dynamics between 2015 and 2020. Method: It is a mixed-type ecological study After calculating the VC, the following four categories were created: very low, low, adequate, and high, and the spatial autocorrelation of VC was analyzed using the Global and Local Moran’s statistics. The dataset is divided by year and by vaccine type. </p>
VIGET: A web portal for study of vaccine-induced host responses based on Reactome pathways and ImmPort data
<p>Host responses to vaccines are complex but important to investigate. To facilitate the study, we have developed a tool called Vaccine Induced Gene Expression Analysis Tool (VIGET), with the aim to provide an interactive online tool for users to efficiently and robustly analyze the host immune response gene expression data collected in the ImmPort database. VIGET allows users to select vaccines, choose ImmPort studies, set up analysis models by choosing confounding variables and two groups of samples having different vaccination times, and then perform differential expression analysis to select genes for pathway enrichment analysis and functional interaction network construction using the Reactome’s web services. VIGET provides features for users to compare results from two analyses, facilitating comparative response analysis across different demographic groups. VIGET uses the Vaccine Ontology (VO) to classify various types of vaccines such as live or inactivated flu vaccines, yellow fever vaccines, etc. Different variables are classified using our Vaccine Investigation Ontology (VIO). To showcase the utilities of VIGET, we conducted a longitudinal analysis of immune responses to yellow fever vaccines and found an intriguing complex activity response pattern of pathways in the immune system annotated in Reactome, demonstrating that VIGET is a valuable web portal that supports effective vaccine response studies using Reactome pathways and ImmPort data. The portal has been deployed at <a href="https://viget.violinet.org/">https://viget.violinet.org/</a>.</p>
Data and code for: Local infectious disease experience influences vaccine refusal rates: a natural experiment
<p>Vaccination has been critical to the decline in infectious disease prevalence in recent centuries. Nonetheless, vaccine refusal has increased in recent years, with complacency associated with reductions in disease prevalence highlighted as an important contributor. We exploit a natural experiment in Glasgow at the beginning of the 20th century to investigate whether prior local experience of an infectious disease matters for vaccination decisions. Our study is based on smallpox surveillance data and administrative records of parental refusal to vaccinate their infants. We analyse variation between administrative units of Glasgow in cases and deaths from smallpox during two epidemics over the period 1900–1904, and vaccine refusal following its legalisation in Scotland in 1907 after a long period of compulsory vaccination. We find that lower local disease incidence and mortality during the epidemics were associated with higher rates of subsequent vaccine refusal. This finding indicates that complacency influenced vaccination decisions in periods of higher infectious disease risk, responding to local prior experience of the relevant disease, and has not emerged solely in the context of the generally low levels of infectious disease risk of recent decades. These results suggest that vaccine delivery strategies may benefit from information on local variation in incidence.</p>
GIS Data for Optimising Vaccination Center Placement in Flanders and Brussels
<p>This dataset collection contains geospatial data that was used in a study on optimising vaccination center placement in Flanders and Brussels Capital Region (Belgium). The collection includes five raster datasets, a road network dataset in vector format, and datasets of potential vaccination facilities in vector format.</p> <p>The raster datasets provide information on population density, mean age, proximity to the nearest N-road, travel time to the nearest hospital, and node value of collective transport. These datasets cover the region of Flanders and the Brussels Capital Region, and have been normalised on a scale of 0 to 1. The population density data was sourced from Statbel [1], while the road network and the hospital locations were queried from OpenStreetMap [2]. The node value of collective transport dataset was obtained from a study by Verachtert et al. [3].</p> <p>The road network dataset is a multilinestring vector dataset that includes all of the roads in Belgium. This dataset can be used to analyse traffic flow and identify optimal locations for vaccine centers. The two point vector datasets contain the locations of potential vaccination facilities within the province of Antwerp, with one dataset including 14 facilities and the other including 7 facilities. These datasets can be used to evaluate the effectiveness of different vaccine center placement strategies.</p> <p>The geospatial data in this collection is stored in GeoJSON format for the road network and the potential vaccination facilities and GeoTIFF format for the raster datasets and can be accessed and analyzed using a variety of geospatial tools and software.</p>
Attitude and CTM predictions for From Tribal Polarization to Socio-Economic Disparities: Exploring the Landscape of Vaccine Hesitancy on Twitter paper
<p>The presented data pertains to predictions of Attitudes and CTM, generated through the application of Machine Learning models. These models have been extensively elucidated in the research paper titled "From Tribal Polarization to Socio-Economic Disparities: Exploring the Landscape of Vaccine Hesitancy on Twitter". The aforementioned data is available to the public.</p>
Open microdata registers from the Brazilian COVID-19 vaccination campaign
<p>This repository provides the Brazilian Ministry of Health’s (MoH) open microdata registers from the national COVID-19 vaccination campaign used in the paper <em>Age reporting for the oldest old in the Brazilian COVID-19 vaccination database: what can we learn from it?</em></p> <p>The dataset was downloaded on 14 March 2022 and was initially available at openDataSus <a href="https://opendatasus.saude.gov.br/dataset/covid-19-vacinacao">Campanha Nacional de Vacinação contra Covid-19</a> under a <a href="http://creativecommons.org/licenses/by/4.0/?ref=chooser-v1">CC BY 4.0</a> license.</p> <p>The reproducible <em><code>R</code></em> code and other datasets for the paper are available on GitHub at <a href="https://github.com/demographyandme/covid-19-datasus-vacina">Age reporting for the oldest old in the Brazilian COVID-19 vaccination database: what can we learn from it?</a> </p>
Memory or naive T cell origin of VZV gE-specific T cell clonotypes boosted by zoster vaccination.
<p>Subjects were vaccinated with either the live attenuated zoster vaccine (n=5) or recombinant zoster vaccine (n=10). Peripheral blood mononuclear cells were obtained before vaccination (baseline), at peak response approximately one month after vaccination, and after 5 years. The TRB sequences for VZV gE-specific T cell clonotypes were identified from CD4 T cells that proliferated in response to overlapping peptides spanning the VZV gE protein. To assess if the vaccines recruited responses from existing memory or from naive T cells, VZV gE-specific clonotypes were cross-matched to naive and memory CD4 T cell subsets isolated from baseline PBMC.</p> <p>This dataset contains the raw TRB sequences obtained using the Adaptive Biotechnologies Immunoseq platform for:</p> <p>1) peak gE clonotypes</p> <p>2) year 5 gE clonotypes</p> <p>3) baseline memory CD4 T cell subsets</p> <p>4) baseline naive CD4 T cell subsets.</p>
Data used in the study "mRNA vaccination boosts spike-specific T cell memory and promotes expansion of CD45RAint TEMRA-like CD8+ T cells in COVID-19 recovered individuals"
<p>Data associated with an original research study examining T cell responses to mRNA vaccination in COVID-19 recovered individuals. 10X Cell Ranger outputs, bulk TCR sequencing data, and T cell functional (ICS) data in this study have been deposited. Authors KMB and HR contributed equally to this effort. Address correspondence to EWN.</p>
DATASET Skin-Based Vaccination: A Systematic Mapping Review of the Types of Vaccines and Methods Used and Immunity and Protection Elicited in Pigs
<p>Dataset listing all publications used in systematic mapping review. This file contains the dataset, a dictionary and values worksheets for the following publication: </p> <p>Skin-Based Vaccination: A Systematic Mapping Review of the Types of Vaccines and Methods Used and Immunity and Protection Elicited in Pigs.</p> <p>Vaccines 2023</p> <p><a href="https://pubmed.ncbi.nlm.nih.gov/?sort=date&size=200&term=C%C3%B3-Rives+I&cauthor_id=36851328">Inés Có-Rives</a> <a href="https://pubmed.ncbi.nlm.nih.gov/36851328/#full-view-affiliation-1">1</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/?sort=date&size=200&term=Chen+AY&cauthor_id=36851328">Ann Ying-An Chen</a> <a href="https://pubmed.ncbi.nlm.nih.gov/36851328/#full-view-affiliation-1">1</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/?sort=date&size=200&term=Moore+AC&cauthor_id=36851328">Anne C Moore</a> <a href="https://pubmed.ncbi.nlm.nih.gov/36851328/#full-view-affiliation-1">1</a></p> <ul> <li>PMID: 36851328</li> <li>PMCID: <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/pmc9962282/">PMC9962282</a></li> <li>DOI: <a href="https://doi.org/10.3390/vaccines11020450">10.3390/vaccines11020450</a></li> </ul> <p>The advantages of skin-based vaccination include induction of strong immunity, dose-sparing, and ease of administration. Several technologies for skin-based immunisation in humans are being developed to maximise these key advantages. This route is more conventionally used in veterinary medicine. Skin-based vaccination of pigs is of high relevance due to their anatomical, physiological, and immunological similarities to humans, as well as being a source of zoonotic diseases and their livestock value. We conducted a systematic mapping review, focusing on vaccine-induced immunity and safety after the skin immunisation of pigs. Veterinary vaccines, specifically anti-viral vaccines, predominated in the literature. The safe and potent skin administration to pigs of adjuvanted vaccines, particularly emulsions, are frequently documented. Multiple methods of skin immunisation exist; however, there is a lack of consistent terminology and accurate descriptions of the route and device. Antibody responses, compared to other immune correlates, are most frequently reported. There is a lack of research on the underlying mechanisms of action and breadth of responses. Nevertheless, encouraging results, both in safety and immunogenicity, were observed after skin vaccination that were often comparable to or superior the intramuscular route. Further research in this area will underlie the development of enhanced skin vaccine strategies for pigs, other animals and humans.</p> <p><strong>Keywords: </strong>epicutaneous; epidermal; intradermal; needle-free; percutaneous; pig; skin; transcutaneous; transdermal; vaccine.</p>
Classifying COVID-19 vaccine narratives
<p>We release the augmented Twitter dataset of 355 vaccine-related narratives, created for the following paper. The tweets are labelled as one of four classes: <em>Conspiracy (Cons), Moral, Religious, and Ethical Concerns (MRE), Liberties and Freedom (LF), and Animal Vaccines (AnimalVac)</em>.</p> <pre>@article{li2022classifying, title={Classifying COVID-19 vaccine narratives}, author={Li, Yue and Scarton, Carolina and Song, Xingyi and Bontcheva, Kalina}, journal={arXiv preprint arXiv:2207.08522}, year={2022} }</pre> <p>The paper has been accepted by RANLP 2023.</p> <p> </p> <p> </p>
Factors Driving Vaccine Hesitancy rrelated to vaccination of children with Covid-19 vaccine among Albanian parents
<p>A validated questionnaire composed of 33 elements was used for the purpose of this study</p> <p>The subjects of this study were parents of children aged 0-18 years old .</p> <p>Inclusion criteria were:albanian parents who understood and spoke well albanian, parents of children aged 0-18 years old, parents aged 18 years old and over. Exclusion criteria were: parents aged less than 18 years old, albanian parents who didn’t understand well albanian language, parents of children aged more than 18 years old.</p>
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.