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12,455 results for “Promoters”
Raw data for article "Palladium-Catalyzed trans-Hydroalkoxylation: Counterintuitive Use of an Aryl Iodide Additive to Promote C-H Bond Formation"
<p>Raw NMR, IR and HPLC data for the article "Palladium-Catalyzed trans-Hydroalkoxylation: Counterintuitive Use of an Aryl Iodide Additive to Promote C-H Bond Formation" published in ACS Catalysis, DOI: </p> <p><a href="https://doi.org/10.1039/D2CC00167E">https://doi.org/10.1021/acscatal.2c01809</a> </p> <p>The main folders correspond to the different parts of the manuscript and the number of the subfolders correspond to compounds numbers in the article. All details concerning conditions and equipment for measurements can be found in the supporting information of the article.</p>
LPCAT1 promotes cSCC development via EGFR
<p>Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer. LPCAT1, a lysophosphatidylcholine acyltransferase, takes a center stage in membrane lipid remodeling. LPCAT1 is elevated in several cancers and contributes to cancer development. However, its role and molecular mechanisms in cSCC remain to be elucidated. In this study, we found that LPCAT1 was upregulated in cSCC tissues and in cell lines. In vitro, loss-of-function and gain-of-function experiments demonstrated that LPCAT1 facilitated cSCC cell proliferation, protected cells against apoptosis, accelerated epithelial‒mesenchymal transition, and enhanced cell metastasis. Mechanistically, LPCAT1 regulated EGFR signaling. The oncogenic effect of LPCAT1 was mediated by EGFR/protein kinase B and EGFR/p38MAPK pathways in cSCC. Using the xenograft mouse model, we consolidated the results mentioned earlier. In conclusion, LPCAT1 contributed to cSCC progression through EGFR-mediated protein kinase B and p38MAPK signaling pathways. LPCAT1 may serve as a target for therapeutic intervention in cSCC. And the datasets related to this study are available in this repository.</p>
Promoting extinction or minimizing growth? The impact of treatment on trait trajectories in evolving populations - Data
<p>This is the dataset used in the manuscript "Promoting extinction or minimizing growth? The impact of treatment on trait trajectories in evolving populations" by Raatz &Traulsen. The code used to generate the data can be found at https://doi.org/10.5281/zenodo.6656842.</p>
Data from: Forests as promoters of terrestrial life history strategies in East African amphibians
Many amphibian lineages show terrestrialization of their reproductive strategy and breeding is partially or completely independent of water. A number of causal factors have been proposed for the evolution of terrestrialized breeding. While predation has received repeated attention as a potential factor, the influence of others such as habitat has never been tested using appropriate data or methods. Using a dataset that comprises 180 amphibian species from various East African habitats, we tested whether species occurring in different habitats show different patterns of terrestrialization in their breeding strategy. We recovered a significant association between terrestrialized breeding strategies and forest habitats. In general, forest seems to act as a facilitator, providing a permissive environment for the evolution of terrestrialized breeding strategies. However, while terrestrial oviposition is strongly correlated with lowland and montane forest habitat, complete terrestrial development is significantly correlated with montane forest only, indicating different selective pressures acting at different steps towards complete terrestrial development.
Downregulation of ST6GAL1 promotes liver inflammation and predicts adverse prognosis in hepatocellular carcinoma
<p>Original file of <em>Downregulation of ST6GAL1 promotes liver inflammation and predicts adverse prognosis in hepatocellular carcinoma.</em></p>
Supplementary Information: CHAPTER 2 - Unveiling genomic features linked to traits of plant-growth-promoting bacterial communities from sugarcane
<p>Appendix A. Summary of counts of subreads and circular consensus sequencing (CCS) sequences obtained for PacBio sequencing of SMRT libraries. (EMS_1.xlsx)</p> <p>Appendix B. Taxonomy assignment of MAGs at the higher taxonomic rank obtained from GTDB-tk and Kraken tools. (EMS_2.xlsx)</p> <p>Appendix C. Report of the classification workflow using GTDB-tk. (EMS_3.xlsx)</p> <p>Appendix D. Matrix of the KEGG Orthology (KOs) frequencies annotated by the EnrichM tool. (EMS_4.xlsx)</p> <p>Appendix E. Reconstruction and completeness of KEGG modules annotated by EnrichM. The asterisks (*) in the header represent additional values obtained by the script ‘classKEGGModules.pl’ (https://github.com/dgpinheiro/bioinfoutilities) to estimate PGPTs in KEGG modules. (EMS_5.xlsx)</p> <p>Appendix F. The secondary metabolite biosynthesis gene clusters (BGCs) identified with AntiSMASH. (EMS_6.xlsx)</p> <p>Appendix G. The raw count of plant growth-promoting traits (PGPTs) annotations, according to KEGG Orthology (KO) predictions for MAGs. (EMS_7.xlsx)</p> <p>Appendix H. The raw count of plant growth-promoting traits (PGPTs) that comprises the 39 classes (level 5 hierarchy) identified as enriched according to the results of Pearson's Chi-square test (qvalue ≤ 0.1). (EMS_8.xlsx)</p>
Data for: Intersectin1 promotes clathrin-mediated endocytosis by organizing and stabilizing endocytic protein interaction networks
Open the record for dataset details and reuse information.
RNA-seq Data for Bacteroides fragilis Toxin Suppresses METTL3-Mediated m6A Modification in Macrophage to Promote Inflammatory Bowel Disease
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Promoting conservation agriculture through push-pull technology as an agroecological transition.
<p>Abstract <br>Low soil fertility, weeds, pests, and climatic change severely threaten crop productivity and agricultural <br>sustainability, especially in SSA. Despite decades of research finding adequate technical solutions for most <br>situations of food systems, the problem of low food productivity has persisted. In an effort to counter this, <br>intensive agricultural systems have been mooted including the high application of agrochemicals to control <br>weeds, and pests and increase production. However, these initiatives have not lasted beyond the project cycle <br>and they have instigated land degradation through unsustainable practices. As a solution, conservation <br>agricultural practices have been promoted among small-scale farmers. These practices focus on minimizing soil <br>disturbance, crop diversification, and cover cropping. Push-pull technology is an aspect of conservation <br>agriculture where intercropping a cereal crop with a repellent plant, such as desmodium and planting an <br>attractive trap plant, such as brachiaria or Napier grass as a border crop around this intercrop. This paper aimed <br>at reviewing existing literature to establish the linkage between conservation agriculture components, push-pull <br>technology, and a sustainable agroecological transition. A list of questions directed the discussion where push<br>pull technology has been proven to be an aspect that promotes conservation agriculture. It has been able to <br>increase crop yields, reduced tillage, established a cover crop on the farm, and further, PPT has a regenerative <br>aspect through the integration of livestock husbandry providing organic manure that and together with the <br>nitrogen fixation ability of the grass, improve soil fertility, conserved soil moisture, and reduce erosion. This <br>reduces the use of inorganic input, and machinery making farming economical for small-holder farmers. </p>
Innate immune responses against the mRNA component of mRNA vaccine promote cellular immunity through IFN-β at the injection site
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Plant growth-promoting rhizobacteria modulate induced corn defense against Spodoptera litura (Lepidoptera: Noctuidae)
<p>Common cutworm, <em>Spodoptera litura</em> is an important pest of corn causing significant crop yield loss. Synthetic insecticides have mostly been used to combat this pest, raising human and environmental health concerns. Plant-growth promoting rhizobacteria (PGPR) could compensate for or augment the harmful effects of agrochemicals. Herein, we aimed to assess whether PGPR-induced defenses in corn plants impact the host-plant selection behavior of <em>S. litura</em>. Headspace volatile organic compounds (VOCs) were analyzed using Gas chromatography-mass spectrometry (GC-MS). Larvae-fed inoculated corn exhibited lower weights and RGR than non-inoculated plants. Under choice experiments, PGPR-treated plants significantly reduced percentage leaf damage area and oviposition rate compared to untreated plants. VOC ratio emission varied significantly between control and PGPR treatments, which, in part, explains feeding and oviposition deterrence in PGPR-treated plants. The results demonstrate that PGPR inoculation can enhance corn resistance to <em>S. litura</em>, making it a promising candidate for crop protection strategies.</p>
Defective Zirconia Promotes Monometallic Iron Catalysts for Higher Alcohol Synthesis
<p>Datasets supporting the publication 'Defective Zirconia Promotes Monometallic Iron Catalysts for Higher Alcohol Synthesis'</p>
Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake
<p>Supporting molecular dynamics (MD) files for the manuscript with the same title. It includes three parts: MD initial files, trajectory files with the membrane and solvent water stripped, and an example binding free energy calculation setting file using Molecular Mechanics Poisson-Boltzmann Surface Area (MM-PBSA) method with an implicit membrane model.</p> <p>The MD initial files include MD parameters (folder 0_mdin) and specific topology (.parm7), initial structure (.rst7), and structural restraint files (.rest) in the corresponding folder for each simulation.</p> <p>The trajectory files include the topology files with membrane and solvent water stripped (.rst7) and 50-snapshot (4 ns interval) coordinate files (.nc) for each MD run.</p> <p>The MM-PBSA setting file (.in) is supposed to be used as the input of the MMPBSA.py utility of the AMBER simulation suite.</p>
Data from: Tree diversity across multiple scales and environmental heterogeneity promote ecosystem multifunctionality in a large temperate forest region
<p><strong>Aim</strong>: Biodiversity across different scales provides multidimensional insurance for ecosystem functioning. Although the effects of biodiversity on ecosystem multifunctionality are well recorded in local communities, they remain poorly understood across scales (from local to larger spatial scales). This study evaluates how multiple attributes of biodiversity maintain ecosystem multifunctionality from local to regional scales, across diverse environmental gradients.</p> <p><strong>Location</strong>: North-eastern China.</p> <p><strong>Time period</strong>: 2017.</p> <p><strong>Major taxa studied</strong>: Woody plants.</p> <p><strong>Methods</strong>: We define multifunctionality using both averaged and modified multiple threshold approaches. Multiple dimensions of biodiversity across varying spatial scales were measured within the framework of Hill‒Chao numbers. Using variance decomposition, linear mixed models, and structural equation modeling, we explored how multiple attributes of tree diversity at varying spatial scales affect multifunctionality, and how these relationships are modulated by environmental drivers.<br>Results: We found that both α- and β-diversity are critical for regional community multifunctionality, while the relationships between species, functional, and phylogenetic diversity and multifunctionality decoupled across spatial scales and thresholds of ecosystem functioning. Phylogenetic β-diversity and species α-diversity are respectively more important for promoting high and moderate threshold multifunctionality (e.g., EMFT90 and EMFT50) in regional communities. Environmental drivers typically have stronger effects than biodiversity on multifunctionality. Soil and climatic conditions had either direct effects on multifunctionality, or indirect ones mediated by species α-diversity. Environmental heterogeneity is important for high threshold multifunctionality, exerting directly and indirectly through phylogenetic β-diversity. Latitude not only directly influences multifunctionality but also modulates it through species α-diversity and phylogenetic β-diversity.</p> <p><strong>Main conclusions</strong>: This study underscores the positive effects of biodiversity on multifunctionality across multiple dimensions. Based on our findings, we conclude that any design of a forested landscape that is aimed at maximizing multifunctionality should consider maintaining high local diversity as well as forest community heterogeneity at varying scales.</p>
Processed data for the manuscript: Promoting Multi-Task Learning as a General Approach for Deep-Learning-based Hydrological Models
<div> <div>Below is a brief overview of the processed data in this repository:</div> <br> <div>- camels_streamflow: This directory contains streamflow data for CAMELS basins covering the period from January 1, 2015, to December 31, 2021. We have not included the original CAMELS dataset, which contains attributes, meteorological forcing, and streamflow data from January 1, 1980, to December 31, 2014, as it can be easily downloaded from the CAMELS website (https://gdex.ucar.edu/dataset/camels.html) and is too large for us to upload to Zenodo.</div> <div>- modiset4camels: This directory includes multiple versions of basin-mean Evapotranspiration (ET) data retrieved from the MOD16A2 data product. The dataset spans from January 1, 2001, to December 31, 2021, with an 8-day temporal resolution.</div> <div>- nldas4camels: This directory contains basin-mean daily meteorological forcing data from the NLDAS-2 dataset, obtained via Google Earth Engine (GEE). The dataset covers the period from January 1, 2001, to December 31, 2021.</div> <div>- smap4camels: This directory features basin-mean Soil Moisture (SSM) data from the NASA-USDA Enhanced SMAP Global Soil Moisture dataset, covering the period from April 2, 2015, to October 3, 2021. The dataset provides SSM measurements at a 5 cm depth. Additionally, we provide basin-mean daily SMAP L4 data spanning from April 1, 2015, to December 31, 2023.</div> </div>
The lateral habenula integrates age and experience to promote social transitions in developing rats
<p>This is the tabular source data associated with the manuscript "The lateral habenula integrates age and experience to promote social transitions in developing rats." Preprint DOI: https://doi.org/10.1101/2024.01.12.575446</p>
Computation noise promotes zero-shot adaptation to uncertainty during decision-making in artificial neural networks
<p>This dataset contains the behavioral choice data obtained from N = 230 participants that played a two-armed bandit task (139 females, age: 34 +/- 10 years) in partial and complete feedback conditions, as described in (Findling, Skvortsova et al., 2019, Nature Neuroscience, https://doi.org/10.1038/s41593-019-0518-9).</p> <div> <div> <div> <p>The experiment was performed on the Prolific platform (prolific.co) and the research was carried out following the principles and guidelines for experiments including human participants provided in the declaration of Helsinki and approved by the relevant authorities (Inserm Ethical Review Committee, IRB #00003888). All participants provided written informed consent prior to their inclusion.</p> </div> </div> </div>
Dataset - Membrane-localized magnetic hyperthermia promotes intracellular delivery of cell-impermeant probes
<p><span>Data regarding the MNP surface temperature estimation, magnetic measurements, and qPCR data for the HSP expression.</span></p> <p><span>The data set is related to the article "Membrane-localized magnetic hyperthermia promotes intracellular delivery of cell-impermeant probes", submitted to Nanoscale</span></p>
Health communication materials developed to promote NCD screening in Ethiopia
<p>These health communication materials are developed by the School of Public Health, Addis Ababa University to promote NCD screening in Ethopia. </p>
MADFORWATER: WP3: Adaptation of technologies for efficient water management and treated wastewater reuse in agriculture: Task3.1: Reduction of crop water requirement and tools for irrigation management with treated WW: Subtask 3.1.1: Plant Growth Promotion (PGP) bacteria to enhance crop resistance to water stress and salinity
<p>This dataset contains the data underlying the following publication: Hassen W, Neifar M, Cherif H, Najjari A, Chouchane H, Driouich RC, Salah A, Naili F, Mosbah A, Souissi Y, Raddadi N, Ouzari HI, Fava F and Cherif A (2018) Pseudomonas rhizophila S211, a New Plant Growth-Promoting Rhizobacterium with Potential in Pesticide-Bioremediation. Front. Microbiol. 9:34. doi: 10.3389/fmicb.2018.00034</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.