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1,923 results for “compounds”
Optical and NMR spectra along with atomic coordinates of the title compounds for: Deciphering the Enigma of Unusual Fluorescence in Weakly Coupled Bis-nitro-pyrrolo[3,2-b]pyrroles
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Score compounds using 275 frequent hitter rules published in the Lilly-Medchem-Rules
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Peptidomimetics-based identification of FDA approved compounds inhibiting IRE1 activity: Simulation Data
<p>Protocols and data sets for docking and MD simulations of Methotrexate, Cefoperazone, Folinic acd and Folic acid interaction with IRE1. All docking data based on Glide (Schrödinger), and all MD simulations are based on the Gromacs software. 2D interaction maps from the initial docking of the four molecules to the four Lysine sites, and from snapshots every 100 ns of the 500 ns MD simulations of the molecules interacting with Lys599 (kinase site) and Lys907 (RNase site). 2D interaction maps produced using Schrödinger. </p>
Figure 2 from: Kyslychenko OA, Protska VV, Zhuravel IO (2019) HPLC determination of phenolic compounds content in Parmelia sulcata and Parmelia vagans thalli. Pharmacia 66(4): 161-164. https://doi.org/10.3897/pharmacia.66.e35194
Figure 2 The HPLC chromatograms of Parmelia vagans thalli under the conditions of positive (A) and negative (B) ionization.
Figure 1 from: Kyslychenko OA, Protska VV, Zhuravel IO (2019) HPLC determination of phenolic compounds content in Parmelia sulcata and Parmelia vagans thalli. Pharmacia 66(4): 161-164. https://doi.org/10.3897/pharmacia.66.e35194
Figure 1 The HPLC chromatograms of Parmelia sulcata thalli under the conditions of positive (A) and negative (B) ionization.
Interfacial photochemistry of biogenic surfactants: a major source of abiotic volatile organic compounds?
<p> </p> <p>Electronic supplementary Information to the Faraday Discussions article:</p> <p>Interfacial photochemistry of biogenic surfactants: a major source of abiotic volatile organic compounds?</p> <p>https://doi.org/10.1039/C7FD00022G</p>
Fig. 1 in Anesthesia of tambaqui Colossoma macropomum (Characiformes: Serrasalmidae) with the essential oils of Aniba rosaeodora and Aniba parviflora and their major compound, linalool
Fig. 1. Relationships of concentration x anesthesia induction or recovery time in tambaqui, Colossoma macropomum, exposed to the essential oils. a. Aniba rosaeodora (EOAR); deep sedation: y=24.8+(8300/x), r2=0.705, deep anesthesia: y=-102.3+(36527/x), r2=0.913. Light sedation and recovery: no significant relationship. b. Aniba parviflora (EOAP); light sedation: y=2.08+(6563/x), r2=0.832, deep sedation: y=13.2+(10098/x), r2=0.703, deep anesthesia: y=-79.8+(41067/x), r2=0.906. Recovery: no significant relationship. y = time to reach stage or recovery (s) and x = concentration (µL L-1).
Evaluating the inhibition of ALK2 phosphorylation of SMAD1/5 by M4K lead compounds in DIPG patient-derived cells (SU-DIPG-IV, HSJD-DIPG-007, HSJD-DIPG-018 and SU-DIPG-XXI)
<p>The binding potency of M4K compounds to ALK2 has been assayed in biochemical assay and cellular assays in HEK293 or C2C12 myoblast cell lines. However, the potency of ALK2 inhibition by M4K compounds has not determined directly in DIPG patient-derived cell lines. While no major deviation from existing assay data is expected, direct experimental evidence is essential.</p> <p>DIPG cells will be trypsinized and resuspended in TSM-base medium without any growth factor for one-hour starvation. Subsequently, equal volume of TSM-base with 2X Activin A (200ng/mL) and M4K compounds or DMSO vehicle control will be added. After one-hour treatment, the cells will be pelleted and lysed in buffer with protease and phosphatase inhibitors for Western Blot analysis.</p> <p>For other related studies, please refer to my opennotebook blog.</p> <p><a href="https://openlabnotebooks.org/evaluating-the-inhibition-of-alk2-phosphorylation-of-smad1-5-by-m4k-lead-compounds-in-dipg-patient-derived-cells-su-dipg-iv-hsjd-dipg-007-hsjd-dipg-018-and-su-dipg-xxi/">https://openlabnotebooks.org/evaluating-the-inhibition-of-alk2-phosphorylation-of-smad1-5-by-m4k-lead-compounds-in-dipg-patient-derived-cells-su-dipg-iv-hsjd-dipg-007-hsjd-dipg-018-and-su-dipg-xxi/</a></p>
Journal articles containing the compound term marketer behavior/behaviour
<p>This file contains a list of all journal articles found at September 2019 that contain the compound term 'marketer behavior' or 'marketer behaviour'.</p>
Turbulence Structure and Momentum Exchange in Compound Channel Flows with Shore Ice covered on the Floodplains
<p>This data deposit contains all the datasets needed to draw 9 Figures (4, 8-10, 12-16) in the paper "Turbulence Structure and Momentum Exchange in Compound Channel Flows with Shore Ice covered on the Floodplains", which is now under consideration for potential publication in Water Resources Research. </p>
Figure 1 in Bornean caterpillar (Lepidoptera) constructs cocoon from Vatica rassak (Dipterocarpaceae) resin containing multiple deterrent compounds
Figure 1. Stages in cocoon construction showing (A) larva reaching out to detach new pieces of resin from dried sheets on the tree trunk; (B) building pieces of resin into one of the two walls; (C) pulling together the two walls using threads of silk; and (D) the completed cocoon.
Figure 2 from: Shui Y-M, Guo S-W, Chen L, Chen W-H (2020) Two new species of Paraboea (Gesneriaceae) in Caryota obtusa forests in Southwest China, with compound and simple dichasia, respectively. In: Shui Y-M, Chen W-H, Ren M-X, Wen F, Hong X, Qiu Z-J, Wei Y-G, Kang M (Eds) Taxonomy of Gesneriaceae in China and Vietnam. PhytoKeys 157: 207-216. https://doi.org/10.3897/phytokeys.157.32534
Figure 2 Paraboea myriantha Y.M. Shui & W.H. Chen, sp. nov. (A, C–G, J) and its similar species P. glutinosa (B, H, I) A, B habitat C abaxial surface of leaf D flower bud E lateral view of flower F bird view of flower G, H front view of flower I lateral view of flower J flower and fruits (A and C photographed by Gui-Liang Zhang and all the others by Yu-Min Shui).
Figure 1 from: Shui Y-M, Guo S-W, Chen L, Chen W-H (2020) Two new species of Paraboea (Gesneriaceae) in Caryota obtusa forests in Southwest China, with compound and simple dichasia, respectively. In: Shui Y-M, Chen W-H, Ren M-X, Wen F, Hong X, Qiu Z-J, Wei Y-G, Kang M (Eds) Taxonomy of Gesneriaceae in China and Vietnam. PhytoKeys 157: 207-216. https://doi.org/10.3897/phytokeys.157.32534
Figure 1 The geographical distribution of Paraboea brevipedunculata W.H. Chen & Y.M. Shui, sp. nov. (square) and P. myriantha Y.M. Shui & W.H. Chen, sp. nov. (star).
Figure 3 from: Shui Y-M, Guo S-W, Chen L, Chen W-H (2020) Two new species of Paraboea (Gesneriaceae) in Caryota obtusa forests in Southwest China, with compound and simple dichasia, respectively. In: Shui Y-M, Chen W-H, Ren M-X, Wen F, Hong X, Qiu Z-J, Wei Y-G, Kang M (Eds) Taxonomy of Gesneriaceae in China and Vietnam. PhytoKeys 157: 207-216. https://doi.org/10.3897/phytokeys.157.32534
Figure 3 Paraboea brevipedunculata W.H. Chen & Y.M. Shui, sp. nov. A habit B adaxial surface of leaf C abaxial side of leaf D adaxial surface of leaf, showing indumentum E, F abaxial surface of leaves, showing indumenti G dichasia H front view of flower I vertical view of flower, showing bracteoles (br) and calyx lobe (ca) J opened corolla, showing staminodes (sta) and pistil K pistil with calyx lobes (All photographed by Yu-Min Shui).
Short-term exposure to the simple polyphenolic compound gallic acid induces neuronal hyperactivity in zebrafish larvae
<p>Zebrafish locomotor test</p> <p>Larval locomotion in zebrafish was investigated at 72 hpf using the automated analyzer DanioVision<sup>TM</sup> Observation Chamber (Noldus Information Technology). Larvae were individually exposed to 50 µg/ml GA dissolved in E3 medium. The activity was measured at three time points: 30, 60, and 180 min. The activity measured in treated and control larvae included: 1) total distance covered by each larva (total distance, in mm), 2) total time larvae spent moving (movement, in seconds), 3) mean velocity of each larva across movement measures (velocity, in mm/sec), 4) total number of rotations completed by each larva during the experiment (one rotation was counted every time larvae turned more than 180° left or right with respect to its own body axis, counted as the frequency of left and right rotations).</p> <p> </p> <p>Cadmium treatment of zebrafish larvae</p> <p>Two batches of wild-type larvae were exposed for 3 h (from 69 to 72 hpf) to 50 and 100 µM CdCl<sub>2</sub>·H<sub>2</sub>O in an E3 medium, respectively. Half of the 50 µM and half of the 100 µM treated larvae underwent the exposition to 50 µg/ml GA. The four obtained subgroups were: <em>i.</em> Cd 50 µM only treated larva; <em>ii.</em> <em>Cd 100</em> µM only treated; <em>iii</em>. Cd 50 µM exposed to GA larvae; and <em>iv</em>. 100 µM exposed to GA larvae. All the groups underwent the behavioral observations reported above. As control groups were used: one group (Control E3) consisting of larvae in E3 medium only, and a second control with larvae exposed to 50 µg/ml GA for 30 minutes only. Larval locomotion was evaluated in a 96-well plate using the automated analyzer DanioVision<sup>TM</sup> Observation Chamber (Noldus Information Technology). Each experiment was performed in triplicate.</p> <p> </p> <p>Neurotransmitter analyses</p> <p>Neur_data report the final concentration expressed as ng of neurotransmitter per larva.</p>
Figure 5 from: Okechukwu P, Sharma M, Tan WH, Chan HK, Chirara K, Gaurav A, Al-Nema M (2020) In-vitro antidiabetic activity and in-silico studies of the binding energies of palmatine and the standard compounds with the three receptors of alpha amylase, alpha glucosidase, and DPP-IV enzyme. Pharmacia 67(4): 363-371. https://doi.org/10.3897/pharmacia.67.e58392
Figure 5 Docking interaction and binding mode of palmatine and alpha-amylase enzyme. The π-π staked interactions are presented in magenta dotted lines.
Figure 8 from: Okechukwu P, Sharma M, Tan WH, Chan HK, Chirara K, Gaurav A, Al-Nema M (2020) In-vitro antidiabetic activity and in-silico studies of the binding energies of palmatine and the standard compounds with the three receptors of alpha amylase, alpha glucosidase, and DPP-IV enzyme. Pharmacia 67(4): 363-371. https://doi.org/10.3897/pharmacia.67.e58392
Figure 8 Docking interaction and binding mode of sitagliptin and DPP-IV enzyme. The hydrogen bonds are presented in green dotted lines, the π-π staked interactions are presented in magenta dotted lines and the π-alkyl interactions are presented in pink dotted lines.
Figure 4 from: Okechukwu P, Sharma M, Tan WH, Chan HK, Chirara K, Gaurav A, Al-Nema M (2020) In-vitro antidiabetic activity and in-silico studies of the binding energies of palmatine and the standard compounds with the three receptors of alpha amylase, alpha glucosidase, and DPP-IV enzyme. Pharmacia 67(4): 363-371. https://doi.org/10.3897/pharmacia.67.e58392
Figure 4 Docking interaction and binding mode of acarbose and alpha-amylase enzyme. The hydrogen bonds are presented in green dotted lines.
Figure 7 from: Okechukwu P, Sharma M, Tan WH, Chan HK, Chirara K, Gaurav A, Al-Nema M (2020) In-vitro antidiabetic activity and in-silico studies of the binding energies of palmatine and the standard compounds with the three receptors of alpha amylase, alpha glucosidase, and DPP-IV enzyme. Pharmacia 67(4): 363-371. https://doi.org/10.3897/pharmacia.67.e58392
Figure 7 Docking interaction and binding mode of palmatine and alpha-glucosidase enzyme. The hydrogen bonds are presented in green dotted lines and the π-alkyl interactions are presented in pink dotted lines.
Figure 2 from: Okechukwu P, Sharma M, Tan WH, Chan HK, Chirara K, Gaurav A, Al-Nema M (2020) In-vitro antidiabetic activity and in-silico studies of the binding energies of palmatine and the standard compounds with the three receptors of alpha amylase, alpha glucosidase, and DPP-IV enzyme. Pharmacia 67(4): 363-371. https://doi.org/10.3897/pharmacia.67.e58392
Figure 2 Alpha-glucosidase enzyme inhibting activity ((IC50(µM) of palmatine, glimepiride, metformin and standard drug(acarbose). The result are shown as Mean ± standard deviation in triplicates (n = 3). The data were statistically analyzed by One-way ANOVA followed by Dunnet's post hoc test. Graph showed that acarbose(a) vs. glimepiride = p < 0.0001 = d; acarbose vs. metformin = p < 0.0001 = d; acarbose vs. palmatine = p < 0.0001 = d. Glimepiride vs. metformin = No significant = d, glimepiride vs. palmatine = No significant = d and metformin vs. palmatine = No significant = d.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.