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1,544
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Dataset results
1,544 results for “microenvironment”
BRAF V600E in Pediatric Low-Grade Gliomas: Exploring the Tumor Microenvironment and Immune Cell Infiltration dynamics in vivo.
GEO Series GSE252367. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
An inflammatory state remodels the immune microenvironment and improves risk stratification in acute myeloid leukemia
GEO Series GSE216738. Homo sapiens. 506 samples. Type: Expression profiling by high throughput sequencing.
Tractable mouse TNBC models capture the heterogeneous tumor immune microenvironment and adaptation to PD-L1 blockade
GEO Series GSE292146. Mus musculus. 38 samples. Type: Expression profiling by high throughput sequencing.
Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment (5892)
GEO Series GSE220731. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
Potent anti-tumor immunity and reversal of CD8 T cell exhaustion by spatially and functionally targeting Treg cells in the tumor microenvironment
<p>1×10<sup>6</sup> of splenic GFP<sup>+</sup> Tregs were purified from WT (n=4) and KO mice (n=4) via FACS isolation. RNA was extracted using RNeasy Micro Kit (Qiagen) following its standard protocol and RNA degradation and contamination was monitored on 1% agarose gels. For RNA sequencing, libraries were prepared using NEBNext® Ultra TM RNA Library Prep Kit for Illumina® (NEB, USA) following manufacturer’s recommendations and index codes were added to attribute sequences to each sample. The clustering of the index-coded samples was performed on a cBot Cluster Generation System using PE Cluster Kit cBot-HS (Illumina) according to the manufacturer’s instructions. After cluster generation, the library preparations were sequenced on an Illumina platform and paired-end reads were generated. All samples were prepared at the same time and sequenced on the same lane. Original image data file from high-throughput sequencing platforms (like Illumina) is transformed to sequenced reads (called Raw Data or Raw Reads) by CASAVA base recognition (Base Calling). Raw data in FASTQ format were processed through fastp. In this step, clean data (clean reads) were obtained by removing reads containing adapter and poly-N sequences and reads with low quality from raw data. All the downstream analyses were based on the clean data with high quality. Reference mouse genome and gene model annotation files were downloaded from genome website browser (NCBI/UCSC/Ensembl). Paired-end clean reads were mapped against the reference genome using the Spliced Transcripts Alignment to a Reference (STAR) software. FeatureCounts was used to count the read numbers mapped of each gene. And then RPKM (Reads Per Kilobase of exon model per Million mapped reads) of each gene was calculated based on the length of the gene and reads count mapped to this gene. The FPKM gene expression matrix, R code, DEG list, and targeted gene list are uploaded in this project.</p>
Multiplex immunohistochemistry assay to evaluate the melanoma tumor microenvironment.
<p>Representative images of triple staining. HLA expressed on the surface of the tumor cells (red arrows), nuclear expression of <a href="https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/foxp3">FOXP3</a> on Treg cells (brown arrows) and cytoplasmic expression of GRZB on <a href="https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/t-cells">T cells</a> (green arrows)</p>
A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma
<p>This repository contains R Seurat objects associated with our study titled "<strong>A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma</strong>". </p> <p>This repository contains two Seurat objects stored in .rds files containing processed single-cell RNA sequencing data from the original ‘Discovery’ cohort of the MMRF Immune Atlas study, along with an additional ‘Discovery + Validation’ cohort, as described in the original publication. These .rds files contain Seurat v4 objects with basic cell type annotation and qc metadata. Specific file contents will be detailed below.</p> <div> <p>A copy of the ‘Cell Annotation Dictionary’ is also included, which contains additional details on the individual annotated clusters in the Immune Atlas dataset.</p> <p>Information on how to request additional metadata about these samples and accessing the original fastq files will be detailed at the end of this description</p> </div>
Dataset of spatial transcriptomics of lung adenocarcinoma for analyzing the tumor microenvironment using topological analysis
<p>The human lung adenocarcinoma dataset for 'STopover captures spatial colocalization and interaction in the tumor microenvironment using topological analysis in spatial transcriptomics data'. </p>
pyramids microenvironment
The pyramids are a miniature environment that was created using a 3D blender in a period of less than an hour. I have more options. If you like the model, you can support me with a like and a comment Source: Objaverse 1.0 / Sketchfab
A Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer
ClinicalTrials.gov study NCT02030860. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Investigation of Tumor Microenvironment After CRPC Along With Before and After Neoadjuvant Therapy for Prostate Cancer
ClinicalTrials.gov study NCT05522907. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Tumor Microenvironment Surveillance on Simultaneous Liver Metastases Extensive Stage Small Cell Lung Cancer
ClinicalTrials.gov study NCT05055999. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Exploring the Association of Imaging and Tumor Microenvironment in Urologic Cancer Using Radiogenomic Approach（Radiogenomics-Urinary）
ClinicalTrials.gov study NCT06537037. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Imaging of Tumour Microenvironment in Patients With Oropharyngeal Head and Neck Squamous Cell Carcinoma Using RGD PET/CT Imaging
ClinicalTrials.gov study NCT04222543. IPD Sharing: NO. Countries: 1. Publications: 0.
Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment
ClinicalTrials.gov study NCT05600933. IPD Sharing: YES. Countries: 1. Publications: 0.
The Gene Expression Studies of the Role of Tumor Microenvironments in Tumor Progression
ClinicalTrials.gov study NCT00638040. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Microenvironment of Adipose Tissue in Endocannabinoid System
ClinicalTrials.gov study NCT00978289. IPD Sharing: Not stated. Countries: 1. Publications: 0.
To Assess the Safety of Continuous IV Administration of Plerixafor and Assess Impact on the Immune Microenvironment in Patients With Pancreatic, Ovarian and Colorectal Adenocarcinomas
ClinicalTrials.gov study NCT03277209. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Renal Cell Carcinoma Microenvironment Discovery Project
ClinicalTrials.gov study NCT04005183. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Study of the Medullary Microenvironment in Acute Childhood Leukemia
ClinicalTrials.gov study NCT05792007. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.