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213
datasets available to search
ShareScore release 0.9.0
Dataset results
213 results for “proteasome”
Genetic alterations of SENP6 disrupt DNA repair and proteostasis conferring sensitivity to proteasome inhibition in multiple myeloma
GEO Series GSE303255. Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Protein homeostasis is maintained by proteasomes containing PSMB9 induced by EEF1A2 upon mitochondrial stress
GEO Series GSE196068. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer
GEO Series GSE66543. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
PTEN DEFICIENCY LEADS TO PROTEASOME ADDICTION, A NOVEL VULNERABILITY IN GLIOBLASTOMA
GEO Series GSE163906. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Effect of CRY2 stabilizer and proteasome inhibitor on MDA-MB-231 cells
GEO Series GSE266013. Homo sapiens. 40 samples. Type: Expression profiling by high throughput sequencing; Other.
Neuronal membrane proteasome-derived peptides modulate neuronal signaling
GEO Series GSE227371. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Loss of SELENOW aggravates muscle loss with regulation of protein synthesis and ubiquitin-proteasome system
GEO Series GSE232366. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Transcriptomic profiling of drug-naïve or proteasome inhibitor-resistant myeloma cell lines
GEO Series GSE144249. Mus musculus; Homo sapiens. 15 samples. Type: Expression profiling by high throughput sequencing.
Proteasome degradative activity regulates CD8+ T lymphocyte metabolism and fate specification
GEO Series GSE78750. Mus musculus. 6 samples. Type: Expression profiling by array.
The Proteasome Stress Regulon is Controlled by a Pair of NAC Transcription Factors in Arabidopsis
GEO Series GSE81668. Arabidopsis thaliana. 16 samples. Type: Expression profiling by high throughput sequencing.
Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance
GEO Series GSE190267. Schizosaccharomyces pombe. 30 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Methylome dynamic upon proteasome inhibition by the pseudomonas virulence factor Syringolin A
GEO Series GSE174350. Arabidopsis thaliana. 8 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Impact of proteasome inhibition on nascent transcription of APOBEC3 cytidine deaminases
GEO Series GSE248016. Homo sapiens. 10 samples. Type: Other.
Proteasome inhibition reprograms chromatin landscape in breast cancer
GEO Series GSE241601. Homo sapiens. 102 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Proteasome Stress in Skeletal Muscle Mounts a Long-Range Protective Response that Delays Retinal and Brain Aging [Drosophila]
GEO Series GSE149798. Drosophila melanogaster. 24 samples. Type: Expression profiling by high throughput sequencing.
Loss of the proteasome deubiquitinase USP14 induces growth defects and a senescence phenotype in colorectal cancer cells.
GEO Series GSE248258. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Proteasome inhibition blocks estrogen-dependent gene transcription by decreasing histone H2B monoubiquitination in human breast cancer cells
GEO Series GSE30931. Homo sapiens. 12 samples. Type: Expression profiling by array.
PSMG2-controlled proteasome-autophagy balance mediates the tolerance for MEK targeted therapy in TNBC
GEO Series GSE206748. Homo sapiens. 3 samples. Type: Other.
TRIM33 is an oncogenic transcriptional coactivator stabilizing AR from Skp2-mediated ubiquitin-proteasomal degradation in prostate cancer [ChIP-seq]
GEO Series GSE174109. Homo sapiens. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Exosomes mediate intercellular transfer of non-autonomous tolerance to proteasome inhibitors in mixed-lineage leukemia
<p><strong>Supplementary Materials</strong></p> <p>Figure S1. PI resistance is reversible in MLL cells.</p> <p>Figure S2. PI-treated cell-derived exosomes induce cell cycle arrest and PI resistance in SEM cells.</p> <p>Figure S3. Unsupervised hierarchical clustering heatmap of differentially expressed proteins in RS4;11-Nexo- or RS4;11-Rexo-treated RS4;11 cells.</p> <p>Figure S4. Integrated network nodes and edges related to “upstream” exosomal proteins.</p> <p>Figure S5. Integrated network nodes and edges related to “downstream” genes in the transcriptome profile of recipient cells.</p> <p>Figure S6. Potential therapeutic targets related to exosomal regulatory proteins.</p> <p>Figure S7. TieDIE integration network nodes and edges related to the cell cycle pathway.</p> <p>Figure S8. TieDIE integration network nodes and edges related to the stemness pathway.</p> <p>Figure S9. The original western blot images in this manuscript.</p> <p>Table S1. Differentially expressed proteins in exosomes.</p> <p>Table S2. Nodes of the TieDIE integrated network.</p> <p>Table S3. The exosomal regulatory proteins and the corresponding drugs or compounds.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.