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Dataset results
418 results for “Dimerization”
Bicelle size and lipid/surfactant ratio screening - Gwalp tail anchor dimer simulation - 70 Lipids - q0.38 - PBS neutralized - CHARMM36m - 310K - OPC water model
<p>Bicelle size and lipid to surfactant ratio screening to investigate the influence on spin relaxation data with monomers of a given peptide.</p>
Micelle size screening - eElaB tail anchor dimer simulation - 50 SDS - Na neutralized - CHARMM36m - 310K - OPC water model
<p>Micelle size screening by varying the amount of SDS to investigate the influence on spin relaxation data with dimers of a given peptide.</p>
Micelle size screening - Gwalp tail anchor dimer simulation - 40 SDS - Na neutralized - CHARMM36m - 310K - OPC water model
<p>Micelle size screening by varying the amount of SDS to investigate the influence on spin relaxation data with dimers of a given peptide.</p>
Micelle size screening - Gwalp tail anchor dimer simulation - 70 SDS - Na neutralized - CHARMM36m - 310K - OPC water model
<p>Micelle size screening by varying the amount of SDS to investigate the influence on spin relaxation data with dimers of a given peptide.</p>
Micelle size screening - Gwalp tail anchor dimer simulation - 50 SDS - Na neutralized - CHARMM36m - 310K - OPC water model
<p>Micelle size screening by varying the amount of SDS to investigate the influence on spin relaxation data with dimers of a given peptide.</p>
Micelle size screening - eElaB tail anchor dimer simulation - 40 SDS - Na neutralized - CHARMM36m - 310K - OPC water model
<p>Micelle size screening by varying the amount of SDS to investigate the influence on spin relaxation data with dimers of a given peptide.</p>
Archive of biochemical data sets contained in: Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies
<p>This archive contains all the biochemical data for the study "Guanine-containing ssDNA and RNA induce dimeric and tetrameric SAMHD1 in cryo-EM and binding studies". Further data supporting the structural data in this study is found in pdb and EMD accession numbers PDB ID 8TDV and EMD-41174 (RNA complex SAMHD1-T*<sub>cl</sub>) and PDB ID 8TDW and EMD-41175 (RNA complex SAMHD1-T*<sub>op</sub>). Further proteomics data is found in the Protein Exchange Database (PXD043587). </p>
Dataset for study of inhibition or activation of yeast and human IRE1 dimers, by Quercetin and Quercitrine.
<p>Docked structures, MD trajectories, BPMD simulation files and video of RNase motion cycles in apo scIre1p dimer. </p>
Fig. 10. Compound 4 induced HepG2 cells apoptosis. HepG2 in Artemidubolides A T, cytotoxic unreported guaiane-type sesquiterpenoid dimers against three hepatoma cell lines from Artemisia dubia
Fig. 10. Compound 4 induced HepG2 cells apoptosis. HepG2 cells were treated with different concentrations (0.0, 3.5, 7.0, and 10.5 μM) of 4 for 48 h. (A) and (B) Flow cytometric analysis and cell apoptosis quantification of HepG2 cells. (C) and (D) The apoptosis-related protein levels in hepatoma cells treated with compound 4 for 48 h. Western blot and statistical results of Bax, BCL-2, PARP-1, and cleaved-PARP-1. The results were normalized to the β-actin loading control. *P <0.05, **P <0.01, and ***P <0.001, n = 3.
Fig. 5 in Artemidubolides A T, cytotoxic unreported guaiane-type sesquiterpenoid dimers against three hepatoma cell lines from Artemisia dubia
Fig. 5. The Experimental and calculated ECD spectra of compounds 3, 5, 7, 8, 10, 12, 13, 14, 16, 17, and 19.
Fig. 8. Compound 4 in Artemidubolides A T, cytotoxic unreported guaiane-type sesquiterpenoid dimers against three hepatoma cell lines from Artemisia dubia
Fig. 8. Compound 4 inhibited migration and invasion of HepG2 cells. HepG2 cells were treated with different concentrations (0.0, 3.5, 7.0 and 10.5 μM) of 4 for 48 h. (A) Representative photographs of the Transwell assay showed migrated and invaded cells after incubation. (B) Histogram of migrated and invaded cells after incubation. *P <0.05, **P <0.01, and ***P <0.001, n = 3.
Fig. 7 in Artemidubolides A T, cytotoxic unreported guaiane-type sesquiterpenoid dimers against three hepatoma cell lines from Artemisia dubia
Fig. 7. Cytotoxic activity of different fractions of A.dubia against HepG2 (100.0 μg/mL). Data were expressed as means ± SD (n = 3). Sorafenib with an IC50 value of 14.6 ± 0.4 μM was used as the positive control.
Fig. 5 in Dimeric Erythrina alkaloids as well as their key units from Erythrina variegata
Fig. 5. The dose-dependent response of erythrivarine T in HEI–OC–1 cells treated with neomycin (20 mM). Cell survival (mean ± SD, n = 3) after treatment with various concentrations of compounds and/or neomycin (Neo). The significance was determined by Student's t-test (*p <0.05, **p <0.01, ***p <0.001 vs. neomycin-only group).
Fig. 5 in Isoquinoline alkaloid dimers with dopamine D1 receptor activities from Menispermum dauricum DC
Fig. 5. Dose-dependent curve of compound 1 inhibiting the RFU signals of dopamine on HEK293-D1 cells.
Fig. 4 in Isolation and structural elucidation of bioactive obovatol dimeric neolignans from the bark of Magnolia officinalis var. biloba
Fig. 4. Neuroprotective effects of racemate 1, (+)-1, ()-1, and 5 on glutamic acid-induced injury of SK-N-SH cells (10 μM, means ± SEM, n = 3). ***p <0.001, *p <0.05, **p <0.01. Positive controls: n-butylphthalide (NBP).
Fig. 4 in Linderanoids A-O, dimeric sesquiterpenoids from the roots of Lindera aggregata (Sims) Kosterm
Fig. 4. Inhibition of TGF-β-induced smad-2 phosphorylation by compound 5 in a dose-dependent manner.
Zr–O Ab Initio Training Data Created by Molecular Dynamics, Contour Exploration, and Dimer Searches
<p> These density functional theory calculations span a diverse set of structures in the Zr–O system which was used as machine-learned interatomic potential (MLIP) training data. This data set was used to benchmark different structural evolution methods (molecular dynamics, contour exploration, and dimer searches) for the quality and accuracy of MLIPs trained on them. The data is provided in the .traj format from ASE. Along with data set used in our publication, we provide a large set of extra unused data and a small Python script example for parsing the data set. The set contains 120,068 structures which contain a total of 3,154,158 atoms.</p> <p>For more details, please see our paper:<br> Michael J Waters and James M Rondinelli, <em>J. Phys.: Condens. Matter</em> <strong>34</strong> 385901(2022) (<a href="https://dx.doi.org/10.1088/1361-648X/ac7f73">https://dx.doi.org/10.1088/1361-648X/ac7f73</a>)</p>
Fig. 5. Key 1H-1H in Dimeric and esterified sesquiterpenes from the liverwort Chiastocaulon caledonicum
Fig. 5. Key 1H-1H COSY (bold bonds) and HMBC (blue arrows) correlations for 6 and 7. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Fig. 4. Key 1H-1H in Dimeric and esterified sesquiterpenes from the liverwort Chiastocaulon caledonicum
Fig. 4. Key 1H-1H COSY (bold bonds), HMBC (blue arrows), and NOE correlations (red arrows) for compound 5. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2. Key 1H-1H in Dimeric and esterified sesquiterpenes from the liverwort Chiastocaulon caledonicum
Fig. 2. Key 1H-1H COSY (bold bonds) and HMBC (blue arrows) correlations of 1–4. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.