Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
243
datasets available to search
ShareScore release 0.9.0
Dataset results
243 results for “mitochondrial dysfunction”
Mechanism of Mitochondrial Dysfunction in Spinal and Bulbar Muscular Atrophy
GEO Series GSE140018. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Extensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells
GEO Series GSE63580. Homo sapiens. 246 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Mitochondrial dysfunction charachterizes the multigenerational effects of maternal obesity on MASLD
GEO Series GSE291363. Mus musculus. 18 samples. Type: Expression profiling by high throughput sequencing.
Colon macrophage transcriptomes reveals the impact of mitochondrial dysfunction in ulcerative colitis
GEO Series GSE135033. Mus musculus. 17 samples. Type: Expression profiling by high throughput sequencing.
APOL1 renal-risk variants induce mitochondrial dysfunction (Illumina)
GEO Series GSE85918. Homo sapiens. 24 samples. Type: Expression profiling by array.
Docosahexaenoic acid protects against palmitate-induced mitochondrial dysfunction in diabetic cardiomyopathy
<p>The effects of docosahexaenoic acid (DHA) on fatty acid-induced cardiomyopathy were evaluated in palmitic acid (PA)-induced cytotoxicity in rat primary cardiomyoblasts in vitro; DHA reduced the occurrence of cardiomyopathy and improved cardiac responses to PA; DHA reduced mitochondrial oxidative stress and ameliorated PA-induced lipid toxicity.</p>
Cytochrome P450 induction reverses mitochondrial dysfunction in a parkinsonian model of neurodegeneration
<p><strong>Supplementary material 1. </strong>Mitochondrial fusion dynamics in SH-SY5Y cells. PA-GFP is gradually spread in mitochondria over the 45 minutes of assay. The intensity of fluorescence in the photo-activated area consistently decreases until 15-20% at minute 45. Ds-Red was used as a mitochondrial marker and calibrator. Data represent the normalized pixel intensity (%) ± SEM of at least 3 independent experiments.</p>
dateset relate to article (submitted) Evaluation of mitochondrial dysfunction and idebenone responsiveness in fibroblasts from Leber's Hereditary Optic Neuropathy (LHON) subjects.
<p>raw data related to the article at title</p>
Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction
ClinicalTrials.gov study NCT03960073. IPD Sharing: NO. Countries: 1. Publications: 0.
Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study
ClinicalTrials.gov study NCT04288635. IPD Sharing: NO. Countries: 1. Publications: 0.
Mitochondrial Dysfunction Contributes to Sepsis Induced Cardiac Dysfunction
ClinicalTrials.gov study NCT05148117. IPD Sharing: NO. Countries: 1. Publications: 0.
PGC-1 & MUSCLE MITOCHONDRIAL DYSFUNCTION IN DIABETES: AIMS 1-4
ClinicalTrials.gov study NCT03323788. IPD Sharing: NO. Countries: 1. Publications: 0.
Phenotyping Mitochondrial and Immune Dysfunction in POTS With Targeted Clinical Intervention.
ClinicalTrials.gov study NCT05409651. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular "Powerhouse") Dysfunction
ClinicalTrials.gov study NCT03421899. IPD Sharing: NO. Countries: 1. Publications: 0.
Mitochondrial Dysfunction in Phelan-McDermid Syndrome
ClinicalTrials.gov study NCT02000167. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
ClinicalTrials.gov study NCT06167135. IPD Sharing: NO. Countries: 1. Publications: 0.
PGC-1 & Muscle Mitochondrial Dysfunction in Diabetes
ClinicalTrials.gov study NCT02282423. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Assessing the Role of Mitochondrial Dysfunction in Primary Progressive Multiple Sclerosis
ClinicalTrials.gov study NCT06025903. IPD Sharing: NO. Countries: 1. Publications: 0.
Intensive Exercise to Improve Mitochondrial Dysfunction in Pediatric Obesity
ClinicalTrials.gov study NCT00962806. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Mitochondrial Dysfunction and Insulin Resistance in Skeletal Muscle
ClinicalTrials.gov study NCT04558190. IPD Sharing: NO. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.