Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
6,383
datasets available to search
ShareScore release 0.9.0
Dataset results
6,383 results for “isolates”
The oceanographic isolation of the Ogasawara Islands and genetic divergence in a reef-building coral
<p><strong><span>Aim:</span></strong><span> Due to their spatial isolation, oceanic islands are natural systems to study evolutionary divergence. The Ogasawara Islands belong to the most isolated archipelagos on Earth and are well-known for their high terrestrial endemicity, however, less is known about the marine realm. Here, we analyze the degree of oceanographic isolation of the archipelago based on genetic data of a reef-building coral and a biophysical dispersal model.</span></p> <p><strong><span>Location: </span></strong><span>North-Western Pacific (Ogasawara, Ryukyu, Daito Islands, Guam)</span></p> <p><strong><span>Taxon: </span></strong><em><span>Galaxea fascicularis </span></em><span>L.</span></p> <p><strong><span>Method:</span></strong><span> Three to 15 specimens were sampled at several sites in Ogasawara and its closest potential migration sources in southern Japan and the Mariana Islands (Guam) and RAD-sequenced. 108 specimens from the common Pacific lineages 'L' (Ryukyu- and Daito Islands, Guam) and 'Ogasawara' (Ogasawara) were analyzed with population genetics and demographic modeling<em>.</em> Oceanographic dispersal was investigated by inverse particle tracking using a Lagrangian particle advection simulation based on ROMS and applying biological dispersal parameters of <em>G. fascicularis</em>.</span></p> <p><strong><span>Results:</span></strong><span> The <em>G. fascicularis </em>population in Ogasawara is genetically highly differentiated from the next closest reefs in the region and has diverged from the Ryukyu Islands under very little, asymmetric, eastward migration. Inverse particle tracking confirmed the oceanographic isolation of Ogasawara and showed that the islands are rarely but most likely reached by settlers from the Ryukyu Islands by long-distance-dispersal of exceptionally long-lived larvae (>44 days), with no dispersal <em>vice versa</em>. </span></p> <p><strong><span>Main conclusions: </span></strong><span>Ogasawara is a dispersal sink location and t</span><span>he high degree of genetic differentiation in <em>Galaxea </em>has resulted from strong oceanographic isolation.</span> <span>This research highlights how oceanographic features impact species-level genetic differentiation even in well-dispersed taxa such as broadcast-spawning corals, and they are likely even more pronounced in less vagile organisms<em>.</em> These findings suggest the Ogasawaran Archipelago should be considered an important priority for marine conservation, alongside its high importance for terrestrial conservation. </span></p>
Data for: Reproductive isolating mechanisms contributing to asymmetric hybridization in Killifishes (Fundulus spp.)
<p class="MsoNormal"><span>When species hybridize, one F1 hybrid cross type often predominates. Such asymmetry can arise from differences in a variety of reproductive barriers, but the relative roles and concordance of pre-mating, post-mating prezygotic barriers, and post-zygotic barriers in producing these biases in natural animal populations have not been widely investigated. Here, we study a population of predominantly F1 hybrids between two killifish species (<em>Fundulus heteroclitus</em> and <em>Fundulus diaphanus</em>) in which >95% of F1 hybrids have <em>F. diaphanus</em> mothers and <em>F. heteroclitus</em> fathers (D♀×H♂). To determine why <em>F. heteroclitus</em> x <em>F. diaphanus</em> F1 hybrids (H♀×D♂) are so rare, we tested for asymmetry in pre-mating reproductive barriers (female preference, male aggression) at a common salinity (10 ppt) and post-mating, pre-zygotic (fertilization success) and post-zygotic (embryonic development time and hatching success) reproductive barriers at a range of ecologically relevant salinities (0, 5, 10, and 15 ppt). We found that <em>F. heteroclitus </em>females preferred conspecific males, while <em>F. diaphanus </em>females did not, matching the observed cross bias in the wild. Naturally rare H♀×D♂<em> </em>crosses also had lower fertilization success than all other cross types, and a lower hatching success than the prevalent D♀×H♂ crosses at the salinity found in the hybrid zone centre (10 ppt). Furthermore, the naturally predominant D♀×H♂ crosses had a higher hatching success than <em>F. diaphanus</em> crosses at 10ppt, which may affect their relative abundance. The present study suggests that a combination of incomplete mating, post-mating pre-zygotic and post-zygotic reproductive isolating mechanisms act in concert to produce hybrid asymmetry in </span><span>this system.</span><span> </span></p>
Data for: Geographic isolation reduces genetic diversity of a wide-ranging terrestrial vertebrate, Canis lupus
<p>Genetic diversity is theorized to decrease in populations closer to a species' range edge, where habitat may be suboptimal. However, generalist species capable of long-range dispersal may maintain sufficient gene flow to counteract this, though the presence of significant barriers to dispersal (e.g., large water bodies, human-dominated landscapes) may still lead to, and exacerbate, the edge effect. We used microsatellite data for 2,426 gray wolves (<em>Canis</em> <em>lupus</em>) from 24 sub-populations (groups) to model how allelic richness and expected heterozygosity varied with two measures of range edge (mainland-island position, latitude, and distance from range center) across >7.3 million km<sup>2</sup> of northern North America. We found that allelic richness and expected heterozygosity of island groups was measurably less than that of mainland groups and that these differences increased with the island's distance to the species' range center in the study area. Our results demonstrate how multiple axes of geographic isolation (distance from range center and island habitation) can act synergistically to erode the genetic diversity of wide-ranging terrestrial vertebrate populations despite the counteracting influence of long-range dispersal ability. These findings emphasize how geographic isolation is a potential threat to the genetic diversity and viability of terrestrial vertebrate populations even among species capable of long-range dispersal. </p> <p>This dataset is comprised of four separate sub-datasets, sourced from Carmichael et al. (2007), Musiani et al. (2007), McNay (2006), and a manuscript in progress (referred to as "MacNulty" in the data files, to be first published in Frevol et al. 2023). The raw data are comprised of sample IDs, latitude and longitude points indicating where the sample was collected or recorded, and microsatellite genetic information. To aid in re-use, the raw genetic data has also been formatted and presented for use with common population genetics software (Genepop, MICROCHECKER, Genetix, FSTAT). The dataset also includes spatial data files of the sub-populations described in the study, allelic richness and expected heterozygosity data derived from the raw and spatial data, and the R script used to create the models. </p> <ul> <li>Carmichael LE, Krizan J, Nagy JA, et al (2007) Historical and ecological determinants of genetic structure in arctic canids. Molecular Ecology 16:3466–3483. https://doi.org/10.1111/j.1365-294X.2007.03381.x</li> <li>McNay ME (2006) Preliminary results of parentage analysis using microsatellite markers from an exploited wolf population in central Alaska. Alaska Department of Fish and Game, Division of Wildlife Conservation, Juneau, Alaska</li> <li>Musiani M, Leonard JA, Cluff HD, et al (2007) Differentiation of tundra/taiga and boreal coniferous forest wolves: genetics, coat colour and association with migratory caribou. Molecular Ecology 16:4149–4170. https://doi.org/10.1111/j.1365-294X.2007.03458.x</li> </ul>
Data from: Genetic architectures of postmating isolation and morphology of two highly diverged rockfishes (genus Sebastes)
<p>Postmating isolation is thought to be an important driver of the late stages of speciation. However, relatively little is empirically known about the process compared to other isolating mechanisms that drive the early stages of speciation, especially in non-model organisms. We characterized the genetic architecture of postmating isolation between two rockfishes, <em>Sebastes schlegelii</em> and <em>S. trivittatus</em>, whose reproductive isolation is complete. We examined transmission ratio distortion (TRD) patterns of genetic markers in two reciprocal backcross populations. Markers showing either of the two types of TRD was widespread across the genome, with some of the distorted markers forming extensive clusters around the recombination coldspots. These suggest that the postmating isolation effectively prevents gene flow across the genome and the recombination landscape contributes to the genetic architecture. Comparisons between two backcross families and two developmental stages showed little similarity in the distorted markers, suggesting asymmetry and stage-specificity of the isolation. This may be due to hybrid incompatibility involving maternal factors or extrinsic selection. The lack of sex-ratio distortion in the mapping families suggested that Haldane's rule in terms of hybrid inviability does not hold. Additionally, QTL mapping detected significant QTLs for sex and the morphological traits relevant to speciation and convergence of rockfishes, including body coloration. Genes in the melanocortin system, including <em>agouti-signaling protein 1</em> (<em>asip1</em>) and <em>melanocortin 1 receptor</em> (<em>mc1r</em>), might underlie the horizontal and vertical color patterns on the body, respectively. These findings constitute an essential step towards a comprehensive understanding of speciation and morphological diversification of rockfishes.</p>
Geographic isolation alone does not explain divergence of a group of orchid species across Brazil's campos rupestres sky-islands
<p class="MsoNormal">Mountains play a crucial role in the origin and maintenance of Neotropical biodiversity, but there are still unanswered questions about the diversification of the <em><span>campos rupestres</span></em> (CR), an herbaceous-shrubby sky-island vegetation in Eastern South America. For orchids distributed across this disjunct rock habitat, difficulties with distinguishing morphological taxa add an additional challenge to disentangling the history of divergence. Here, we combined the power of ddRAD genomic data with broad sampling of <em>Bulbophyllum</em> sect. <em>Didactyle</em> (Orchidaceae), across the CR and other Neotropical outcrops, to estimate evolutionary relationships and reconstruct the biogeography of the group's diversification. Although genetic lineages generally align with geographic disjunctions, we also observe distantly related lineages within some previously recognized species. For such taxa, their lack of monophyly and a shared regional divergence pattern suggests a complex history that may include unrecognized diversity. When viewed through the lens of morphological variability, our study raises intriguing questions about the persistence and permeability of species barriers among orchid populations. These results, in addition to the recency of the divergence history of <em>B.</em> sect. <em>Didactyle,</em> provide insights about hypothesized community level versus species-specific paths of diversification across the Neotropical sky-islands of the CR.</p>
Divergent selection on behavioural and chemical traits between reproductively isolated populations of Drosophila melanogaster
<p>Speciation is driven by traits that can act to prevent mating between nascent lineages, including male courtship and female preference for male traits. Mating barriers involving these traits evolve quickly because there is strong selection on males and females to maximize reproductive success, and the tight co-evolution of mating interactions can lead to rapid diversification of sexual behavior. Populations of <em>D. melanogaster</em> show strong asymmetrical reproductive isolation that is correlated with geographic origin. Using strains that capture natural variation in mating traits, we ask two key questions: which specific male traits are females selecting, and are these traits under divergent sexual selection? These questions have proven extremely challenging to answer, because even in closely related lineages males often differ in multiple traits related to mating behavior. We address these questions by estimating selection gradients for male courtship and cuticular hydrocarbons for two different female genotypes. We identify specific behaviors and particular cuticular hydrocarbons that are under divergent sexual selection and could potentially contribute to premating reproductive isolation. Additionally, we report that a subset of these traits are plastic; males adjust these traits based on the identity of the female genotype they interact with. These results suggest that even when male courtship is not fixed between lineages, ongoing selection can act on traits that are important for reproductive isolation.</p>
Annotated VCF of 192 Verticillium dahliae isolates
<p><span></span></p> <p><em>Verticillium dahliae</em> is an important soil-borne pathogen causing Verticillium wilt. It is also the primary causal agent of the Potato Early Dying, a disease complex involving the root-lesion nematode. Here, we report the whole-genome sequencing of 192 isolates of <em>V. dahliae</em> originating from the major potato production areas across Canada. Our results yielded a resource of <span> 277,010 genetic variations</span> that will be useful for genetic analyses and revealed the presence of two major lineages, both present in all provinces but exhibiting differences in regional prevalence.</p>
Efficient isolation of rare B cells using next-generation antigen barcoding
<p><strong>ABSTRACT:</strong> The ability to efficiently isolate antigen-specific B cells in high throughput will greatly accelerate the discovery of therapeutic monoclonal antibodies (<strong>mAbs</strong>) and catalyze rational vaccine development. Traditional mAb discovery is a costly and labor-intensive process, although recent advances in single-cell genomics using emulsion microfluidics allow simultaneous processing of thousands of individual cells. Here we present a streamlined method for isolation and analysis of large numbers of antigen-specific B cells, including next generation antigen barcoding and an integrated computational framework for B cell multi-omics. We demonstrate the power of this approach by recovering thousands of antigen-specific mAbs, including the efficient isolation of extremely rare precursors of VRC01-class and IOMA-class broadly neutralizing HIV mAbs.</p> <p> </p>
Fig. 3. Isolated type A coprolites viewed using transmitted-light microscopy. Scale bars 100 in The ecological role of immature phantom midges (Diptera: Chaoboridae) in the Eocene Lake Messel, Germany
Fig. 3. Isolated type A coprolites viewed using transmitted-light microscopy. Scale bars 100 µm.
Sequence diversity in MAX effectors and other genes in 120 isolates of the rice blast fungus Magnaporthe oryzae
<p>- list_of_accessions_and_assembly_statistics.xlsx: list of 120 isolate and genome assembly statistics</p> <p>- assemblies.zip: genome assemblies with repeats were not masked</p> <p>- orthogroups.txt: list of orthogroups in orthogroups.zip</p> <p>-orthogroups.zip: sequences of orthogroups, as identified using Orthofinder. Sequences were aligned using translatorX (https://doi.org/10.1093/nar/gkq291)</p> <p>- single_copy_orthologs.zip: folder which contains aligned sequences of single-copy orthologs (alignment with translatorX https://doi.org/10.1093/nar/gkq291); three types of genes were distinguished: MAX effectors, other secreted proteins, and other genes; note that to produce this dataset, the 11 orthogroups that included paralogous copies of MAX effectors were split into sets of orthologous sequences using genealogies inferred using RAXML v8, yielding a total of 94 single-copy MAX orthologs; for each split orthogroup, sets of orthologous sequences were assigned a number that was added to the orthogroup’s identifier as a suffix (for instance paralogous sequences of orthogroup OG0000244 were split into orthogroups OG0000244_1 and OG0000244_2)</p>
Drivers of strong isolation and small effective population size at a leading range edge of a widespread plant
<p>Climate change has influenced species distributions worldwide with upward elevational shifts observed in many systems. Leading range edge populations, like those at upper elevation limits, are crucial for climate change responses but can exhibit low genetic diversity due to founder effects, isolation, or limited outbreeding. These factors can hamper local adaptation at range limits. Using the widespread herb, <em>Argentina</em> <em>anserina</em>, we measured ecological attributes (population density on the landscape, area of population occupancy, and plant and flower density) spanning a 1000m elevation gradient, with high elevation populations at the range limit. We measured vegetative clonal potential in the greenhouse for populations spanning the gradient. We combined these data with a ddRAD-seq dataset to test the hypotheses that high-elevation populations would exhibit ecological and genomic signatures of leading range edge populations. We found that population density on the landscape declined towards the high elevation limit, as is expected towards range edges. However, plant density was elevated within edge populations. In the greenhouse, high-elevation plants exhibited stronger clonal potential than low-elevation plants, likely explaining increased plant density in the field. Phylogeographic analysis supported more recent colonization of high-elevation populations which were also more genetically isolated, had more extreme heterozygote excess, and had smaller effective population size than low. Results support that colonization of high elevations was likely accompanied by increased asexuality, contributing to a decline in effective population size. Despite high plant density in leading-edge populations, their small effective size, isolation, and clonality could constrain adaptive potential.</p>
Comparative analysis of two Candida parapsilosis isolates from the patient with a central venous catheter harbouring the Y132F and R398I mutations
<p>This work presents a comparative analysis of 2 clinical isolates of <em>C. parapsilosis</em>; isolated from haemoculture (HC) and central venous catheter (CVC). Both strains harboured Y132F and R398I mutations associated with resistance to fluconazole (FLC). Differences between HC and CVC isolates in terms of virulence, resistance to FLC and lipid distribution were addressed. Expression of the ERG6 and ERG9 genes, lipid analysis, fatty acid composition and lipase activity were assessed by qPCR, thin-layer chromatography/high performance liquid chromatography, gas chromatography and spectrophotometry, respectively. A regulation of the ERG6 and ERG9 genes did not prove any impact on FLC resistance. Analysis of lipid metabolism showed a higher accumulation of lanosterol in both isolates regardless of FLC presence. Additionally, a decreased level in triacylglycerols (TAG) with impact on the composition of total FA was observed for both isolates. Direct impact of the ERG11 mutations to lipid/FA analysis has not been confirmed. The higher lipase activity observed for <em>C. parapsilosis</em> HC isolate could be correlated with the significantly decreased level of TAG. The very close relatedness between both isolates suggests that one isolate was derived from another after the initial infection of the host.</p>
Data from: Replicate contact zones suggest a limited role of plumage in reproductive isolation among subspecies of the Variable Seedeater (Sporophila corvina)
<p>After establishing secondary contact, recently diverged populations may remain reproductively isolated or may hybridize to a varying extent depending on factors such as hybrid fitness and the strength of assortative mating. Here, we used genomic and phenotypic data from three independent contact zones between subspecies of the Variable Seedeater (<em>Sporophila corvina</em>) to examine how coloration and genetic divergence shape patterns of hybridization. We found that differences in plumage coloration are likely maintained by divergent selection across contact zones; however, the degree of plumage differentiation does not match overall patterns of hybridization. Across two parallel contact zones between populations with divergent phenotypes (entirely black vs. pied plumage), populations hybridized extensively across one contact zone but not the other, suggesting that plumage divergence is not sufficient to maintain reproductive isolation. Where subspecies hybridized, hybrid zones were wide and formed by later-generation hybrids, suggesting frequent reproduction and high survivorship for hybrid individuals. Moreover, contemporary gene flow has played an important role in shaping patterns of genetic structure between populations. Replicated contact zones between hybridizing taxa offer a unique opportunity to explore how different factors interact to shape patterns of hybridization. Overall, our results demonstrate that divergence in plumage coloration is important in reducing gene flow but insufficient in maintaining reproductive isolation in this clade, and that other factors such as divergence in song and time since secondary contact may also play an important role in driving patterns of reduced hybridization and gene flow.</p>
FIG. 1 in Morphological description and molecular phylogeny of two diatom clones from the genus Ulnaria (Kützing) Compère isolated from an ultraoligotrophic lake at the Pole of Cold in the Northern Hemisphere, Republic of Sakha (Yakutia), Russia
FIG. 1. — Study site (62°33'33"N; 143°36'27"E), Lake Labynkyr, Sakha Republic (Yakutia), Russia.
Draft Genome Sequences of Two Bacteriocin-Producing Enterococcus faecium Strains Isolated from Nonfermented Animal Foods in Spain
<p>Raw sequences of two bacteriocin-producing Enterococcus faecium.</p> <p> </p>
The role of sexual isolation during rapid ecological divergence: evidence for a new dimension of isolation in Rhagoletis pomonella
<p>The pace of divergence and likelihood of complete speciation may depend on how and when different types of reproductive barriers evolve. Questions remain about the evolution of reproductive barriers after initial divergence. We tested for the presence of sexual isolation (reduced mating between populations due to divergent mating preferences and traits) in <em>Rhagoletis</em> <em>pomonella</em> flies, a model system for incipient ecological speciation. We measured the strength of sexual isolation between two very recently diverged (~170 generations) sympatric populations, adapted to different host fruits (hawthorn and apple). We found that flies from both populations were more likely to mate within than between populations. Thus, sexual isolation may play an important role in reducing gene flow allowed by early-acting ecological barriers. We also tested how warmer temperatures predicted under climate change could alter sexual isolation and found that sexual isolation was markedly asymmetric under warmer temperatures – apple males and hawthorn females mated randomly while apple females and hawthorn males mated within population than between. Our findings provide a window into the early divergence process and the role of sexual isolation after initial ecological divergence, in addition to examining how environmental conditions could shape the likelihood of further divergence.</p>
Analisi isole di calore superficiale
<p>Presso l’Istituto per la Bioeconomia del CNR di Firenze è stato svolto un tirocinio per il Master in Sviluppo Sostenibile e Cambiamenti Climatici dell’Università di Pisa, che ha riguardato l’analisi delle isole di calore superficiale nei capoluoghi di regione italiani per il periodo estivo giugno – agosto, dal 2018 al 2022.</p> <p>Le mappe finali sono state realizzate utilizzando dati vettoriali e raster con sistema di riferimento EPSG:3035 - ETRS89-extended / LAEA Europe e una risoluzione spaziale di 10 m e 30 m liberamente accessibili e reperibili in rete sui siti dell’Agenzia delle Entrate e l’Osservatorio del Mercato Immobiliare (OMI), l’Istituto Superiore per la Protezione e la Ricerca Ambientale (ISPRA).</p> <p>I dati della temperatura superficiale estiva sono relativi alle immagini Landsat 8, analizzate tramite la piattaforma di Google Earth Engine.</p> <p>Le mappe del territorio comunale sono state realizzate con il software open source Qgis, seguendo le indicazioni dell’OMI. che suddivide l’area del comune in fasce (centrale, semicentrale, periferica, suburbana ed extraurbana), ossia in zone omogenee e contigue con una collocazione geografica precisa.</p> <p>Per ogni fascia e considerando solo le zone di pianura (quota < a 300 m) è stata calcolata la temperatura media superficiale del periodo sopracitato.</p> <p>Per concludere lo studio sono stati inseriti negli elaborati cartografici anche i dati relativi alla copertura e al consumo di suolo dell’ISPRA. Nello specifico sono stati valutati per ogni fascia del comune i dati relativi alla superficie impermeabile, alle superfici verdi (erbacee, arbustive ed arboree), ai corpi idrici principali e al suolo nudo.</p>
Temperate zone isolation by climate: an extension of Janzen's 1967 hypothesis
<p>One of the most stunning patterns of the distribution of life on Earth is the latitudinal biodiversity gradient. In an influential paper, Janzen (1967) predicted that tropical mountains are more effective migration barriers than temperate mountains of the same elevation because annual temperature variation in the tropics is lower. A great deal of research has demonstrated that the mechanism envisioned by Janzen operates at broad latitudinal scales. However, the extent that the mechanism mediates biodiversity generally, and at smaller scales, is far less understood. We investigated if climate overlap is associated with genetic similarity between populations within temperate regions using lizards in the Sierra Nevada mountain range, California, as a study system. By comparing genetic differentiation between high- and low-elevation populations, we found that in addition to the expected strong pattern of isolation by distance (IBD), climate overlap values were negatively associated with genetic differentiation, indicating that population pairs that inhabit climatically similar environments are less genetically differentiated. Moreover, while climate overlap between high- and low-elevation sites is predicted to increase from the equator to temperate regions, we find that in adjacent mountain ranges at the same latitude in temperate regions, climate overlap values can vary widely. This study suggests that in addition to the well-studied main effect of latitude on climate overlap and population differentiation, local climate factors within bioclimatic regions can also influence genetic differentiation between populations, and do so by the same general mechanism that operates at larger geographic scales.</p>
Isolation and Redox Reactivity of Cerium Complexes in Four Redox States
<p>This upload contains raw data (NMR, X-Ray, UV, EPR, electrochemistry and Elemental Analysis) files for the article</p>
Data from: Genomic data clarify Aquarana systematics and reveal isolation-by-distance dominates phylogeography of the wide-ranging frog Rana clamitans
<p>Wide-ranging species are often polytypic, span geographic dispersal barriers, and experience opportunities for divergence via genetic drift or natural selection. Such conditions can be favorable for speciation and wide-ranging taxa are frequently subdivided into multiple species by modern molecular studies. However, with wide-ranging species, it is important to explicitly test for isolation-by-distance (IBD) which can produce continuous genetic variation that may be misinterpreted as discrete population structure or even distinct species. Here we examine the Green Frog (<em>Rana clamitans</em>), a wide-ranging species of the Aquarana<em> </em>clade distributed across much of North America. Although <em>Rana clamitans</em> is phenotypically variable enough to previously merit description of two subspecies, patterns of genetic diversity remain unclear. Additionally, the broader phylogenetic context for <em>R. clamitans</em> is poorly understood, particularly its relationship with the closely related and IUCN Vulnerable Bog Frog (<em>Rana okaloosae</em>). Using genome-wide ddRAD markers, we largely resolve relationships within Aquarana<em> </em>and unambiguously identify <em>R. okaloosae </em>as the sister lineage to <em>R. clamitans</em>. Within <em>R. clamitans </em>we find two well-supported and geographically divided clades which are identified as distinct species by a widely used genetic species delimitation method, BPP. However, the two clades exhibit low genealogical divergence and population genetic analyses reveal that genetic variation within <em>R. clamitans</em> is best described by a pattern of IBD rather than independently evolving lineages. We conclude that <em>R. clamitans </em>is<em> </em>indeed a single species and the subspecies concept is of limited use. Our analysis emphasizes how existing approaches can erroneously split species characterized by continuous genetic variation and highlights the power of combining population genetic and phylogenetic perspectives to better understand diversity within wide-ranging taxa.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.