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173
datasets available to search
ShareScore release 0.9.0
Dataset results
173 results for “cancer cachexia”
Impaired cAMP/CREB1 signaling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia.
GEO Series GSE271831. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing.
Pancreatic cancer-induced cachexia syndrome
GEO Series GSE51931. Mus musculus. 18 samples. Type: Expression profiling by array.
Molecular Subtypes of Human Skeletal Muscle in Cancer Cachexia
GEO Series GSE292053. Homo sapiens; Rattus norvegicus. 185 samples. Type: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing.
Cancer-induced FOXP1 disrupts and reprograms skeletal muscle circadian transcription in cachexia [skeletal muscle overexpression of FoxP1 RNA-seq]
GEO Series GSE273879. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.
Targeting of HIF2-driven cachexia in kidney cancer
GEO Series GSE289579. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Cachexia-induced reprogramming of visceral organ metabolism by human pancreatic cancer xenografts
<p>We have uploaded the raw MRS data used in this study. The data were obtained through dual-phase extraction from the heart, lungs, kidneys, pancreas, liver, and spleen samples. Each sample was reconstituted in 650 μL of phosphate-buffered D₂O (90:10 D₂O:H₂O, pH 7.4) with trimethylsilylpropanoic acid (TSP), and analyzed by ¹H MRS.All spectra were acquired using a Bruker 750 MHz NMR spectrometer using single pulse sequence under consistent experimental conditions: a spectral width of 15,495.86 Hz, 64K data points, a 90° flip angle, a relaxation delay of 10 seconds, an acquisition time of 2.11 seconds, and 64 scans with 8 dummy scans. The MRS data were analyzed and quantified using TOPSPIN 4.0.6 software. Spectral processing included zero-filling to 64K and applying an exponential line broadening of 0.3 Hz before Fourier transformation. Peak integration was performed using AMIX software, and the area under each peak was used for quantitative analysis after normalization to the internal standard, TSP (trimethylsilylpropanoic acid). <strong> </strong>We identified, for the first time, the profound effects of pancreatic cancer induced cachexia on visceral organ weight and metabolism that can lead to severe consequences in organ function ranging from affecting pathways involved in tissue regeneration and resolving inflammation, to altering IL-4 production in cachectic mice. These results highlight the damaging systemic changes in visceral organ metabolism that occur with cancer induced cachexia that may lead to metabolic interventions to reduce morbidity and mortality. </p> <p> </p> <p> </p>
Study of Branched-chain Amino Acids in Cancer Cachexia
ClinicalTrials.gov study NCT03253029. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Clinical Study on the Treatment of Anorexia and Cachexia in Advanced Gastric and Esophageal Cancer With Nanosized Megestrol Acetate Combined With Immunochemotherapy
ClinicalTrials.gov study NCT06963593. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Nanocrystalline Megestrol Acetate for the Treatment of Anorexia-Cachexia Syndrome in Extensive-Stage Small Cell Lung Cancer: A Prospective, Open-Label, Single-Arm Phase II Clinical Study
ClinicalTrials.gov study NCT06909383. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Development of a Predictive Model for Gastric Cancer Peritoneal Metastasis and Cachexia Using BUB1 and Radiopathomics Data With Deep Learning
ClinicalTrials.gov study NCT06858644. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Nano-crystalline Megestrol Acetate for Anorexia-Cachexia Syndrome in Advanced Lung Cancer
ClinicalTrials.gov study NCT07092137. IPD Sharing: YES. Countries: 0. Publications: 0.
Nutrition Education and Quality of Life in Cancer Cachexia
ClinicalTrials.gov study NCT05262192. IPD Sharing: NO. Countries: 0. Publications: 0.
Retrospective Review of Cachexia in Lung and Gastrointestinal Cancer Patients
ClinicalTrials.gov study NCT03606317. IPD Sharing: UNDECIDED. Countries: 0. Publications: 0.
Is Clarithromycin a Potential Treatment for Cachexia in People With Lung Cancer?
ClinicalTrials.gov study NCT02416570. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Identification of FoxO target genes during C-26 cancer cachexia
GEO Series GSE56555. Mus musculus. 16 samples. Type: Expression profiling by array.
Skeletal Muscle Methylome-Transcriptome Disruptions During the Onset and Progression of Colorectal Cancer-Induced Cachexia
GEO Series GSE314368. Mus musculus. 88 samples. Type: Methylation profiling by high throughput sequencing.
Cancer-induced FOXP1 disrupts and reprograms skeletal muscle circadian transcription in cachexia [circadian RNA-seq]
GEO Series GSE273878. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.
The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from Males
GEO Series GSE222317. Mus musculus. 40 samples. Type: Expression profiling by high throughput sequencing.
FGF21 deficiency aggravates adipose tissue loss in thermoneutrality-associated cancer cachexia
GEO Series GSE291252. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
YAP disrupts bile acid homeostasis to drive cancer-associated cachexia [Crispant_RNAseq]
GEO Series GSE317420. Danio rerio. 27 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.