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18,621 results for “development;”

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zenodo36/100

Supplementary Material for the Paper "Design Recommendations for Self-Monitoring in the Workplace: Studies in Software Development"

<p>Contains the supplementary material for the paper "Design Recommendations for Self-Monitoring in the Workplace: Studies in Software Development" submitted to CSCW'18. All contents are explained in the file README.txt.</p> <p>Abstract:<br> One way to improve the productivity of knowledge workers is to increase their self-awareness about productivity at work through self-monitoring. Yet, little is known about expectations of, the experience with and the impact of self-monitoring in the workplace. To address this gap, we studied software developers, as one community of knowledge workers. We used an iterative, feedback-driven development approach (N=20) and a survey (N=413) to infer design elements for workplace self-monitoring, which we then implemented as a technology probe called WorkAnalytics. We field-tested these design elements during a three-week study with software development professionals (N=43). Based on the results of the field study, we present design recommendations for self-monitoring in the workplace, such as using experience sampling to increase the awareness about work and to create richer insights, the need for a large variety of different metrics to retrospect about work, and that actionable insights, enriched with benchmarking data from co-workers, are likely needed to foster productive behavior change at work.</p>

opencc-by-4.0Jul 2017View details →
zenodo36/100

Beta-Lactamase X-ray diffraction data recorded at Diamond Light Source I04 as part of commissioning & development

<p>X-ray diffraction data from crystals of beta-lactamase recorded during commissioning. The data were recorded in two omega scans of 3600 images @ 0.1 degrees / frame with different kappa and phi settings on a mini kappa device, with a Dectris PILATUS2 6M detector, at a wavelength of 1.239850A (10keV) for remote-SAD on the native Zn site.</p> <p> </p> <p>Data uploaded for education and tutorial purposes as a good quality example set using multi-axis geometry. </p> <p> </p> <p>For convenience the data are compressed with gzip and combined into one tar file for each sweep.</p>

opencc-by-4.0Aug 2017View details →
zenodo36/100

Disrupted development of sensory systems and the cerebellum in a zebrafish ebf3a mutant

<p>Behavior and imaging data for the ebf3a mutant zebrafish line. Also, Supplementary Data S1, which contains additional RNA-seq analyses and code.</p>

opencc-by-4.0Sep 2024View details →
zenodo36/100

Perturbed Synthetic SWOT Datasets for Testing and Development of a Kalman Filter Approach to Estimate Daily Discharge

<p><strong>1.&nbsp;&nbsp;&nbsp;&nbsp; Introduction</strong></p> <p>Datasets are used to evaluate the performance of a Kalman filter approach to estimate daily discharge. This is a perturbed version of synthetic SWOT datasets consisting of 15 river sections, which are commonly agreed datasets for evaluating the performance of SWOT discharge algorithms (Frasson et al., 2020, 2021). The benchmarking manuscript entitled &ldquo;A Kalman Filter Approach for Estimating Daily Discharge Using Space-based Discharge Estimates&rdquo; is currently under review at Water Resources Research. Once the manuscript is accepted, its DOI will be included here.</p> <p>&nbsp;</p> <p><strong>2.&nbsp; </strong><strong>File description</strong></p> <p>The datasets are generally divided into two categories: river information (River_Info) and time series data (Timeseries_Data). River information provides fundamental and general river characteristics, whereas time series data offers daily reach-averaged data for each reach. In time series data, the data mainly contains three components: true data, perturbed measurements, and true and perturbed flow law parameters (A0, an, and b). For each reach, there are 10000 realizations of perturbed measurements per time step and there are 100 realizations of time-invariant perturbed flow law parameters through a Monte Carlo simulation (Frasson et al., 2023). Moreover, to support our proposed Kalman filter approach to estimate daily discharge, the datasets provide the median of the perturbed discharge, river width, water surface slope, and change in the cross-sectional area, as well as the uncertainty of the perturbed discharge and change in the cross-sectional area based on the interquartile range (Fox, 2015).</p> <p>To support reproducibility and facilitate example usage, we now include a MATLAB code package (<code>KalmanFilter_Code.zip</code>) that demonstrates how to run the Kalman filter approach using the Missouri Downstream case as an example.&nbsp;</p> <p>Datasets are contained in a .mat file per river. The detailed groups and variables are in the following:</p> <p><strong>River_Info</strong></p> <p>Name: River name, data type: char</p> <p>QWBM: Mean annual discharge from the water balance model WBMsed (Cohen et al., 2014)</p> <p>rch_bnd:&nbsp; &nbsp;Reach boundaries measured in meters from the upstream end of the model</p> <p>gdrch: Good reaches in the study. They were used to exclude small reaches defined around low-head dams and other obstacles where Manning&rsquo;s equation should not be applied.</p> <p><strong>Timeseries_Data</strong></p> <p>t: Time measured in days since the first day or &ldquo;0-January-0000&rdquo; for cases when specific dates were available. Dimension: 1, time step.</p> <p>A: Reach-averaged cross-sectional area of flow in m<sup>2</sup>. Dimension: Reach, time step.</p> <p>Q_true: True reach-averaged discharge (m<sup>3</sup>/s). Dimension: Reach, time step.</p> <p>Q_ptb: Perturbed discharge (m<sup>3</sup>/s), including 10000 realizations for each measurement.&nbsp;Dimension: Good reach, time step, 10000.</p> <p>med_Q_ptb: Median perturbed discharge (m<sup>3</sup>/s) across the 10000 realizations. Dimension: Good reach, time step.</p> <p>sigma_Q_ptb: Uncertainty of the perturbed discharge (m<sup>3</sup>/s), calculated based on the interquartile range. Dimension: Good reach, time step.</p> <p>W_true: True reach-averaged river width (m). Dimension: Reach, time step.</p> <p>W_ptb: Perturbed river width (m), including 10000 realizations for each measurement. Dimension: Good reach, time step, 10000.</p> <p>med_W_ptb: Median perturbed river width (m) across the 10000 realizations. Dimension: Good reach, time step.</p> <p>H_true: True reach-averaged water surface elevation (m). Dimension: Reach, time step.</p> <p>H_ptb: Perturbed water surface elevation (m), including 10000 realizations for each measurement. Dimension: Good reach, time step, 10000.</p> <p>S_true: True reach-averaged water surface slope (m/m). Dimension: Reach, time step.</p> <p>S_ptb: Perturbed water surface slope (m/m), including 10000 realizations for each measurement. Dimension: Good reach, time step, 10000.</p> <p>med_S_ptb: Median perturbed water surface slope (m/m) across the 10000 realizations. Dimension: Good reach, time step.</p> <p>dA_true: True reach-averaged change in the cross-sectional area&nbsp;(m<sup>2</sup>). Dimension: Good reach, time step.</p> <p>dA_ptb: Perturbed change in the cross-sectional area (m<sup>2</sup>), including 10000 realizations for each measurement. Dimension: Good reach, time step, 10000.</p> <p>med_dA_ptb: Median perturbed change in the cross-sectional area (m<sup>2</sup>) across the 10000 realizations. Dimension: Good reach, time step.</p> <p>sigma_dA_ptb: Uncertainty of the perturbed change in the cross-sectional area (m<sup>2</sup>), calculated based on the interquartile range. Dimension: Good reach, time step.</p> <p>A0_true: True baseline cross-sectional area&nbsp;(m<sup>2</sup>). Dimension: Good reach, 1.</p> <p>A0: Perturbed baseline cross-sectional area (m<sup>2</sup>), including 100 realizations for each parameter. Dimension: Good reach, 100.</p> <p>na_true: True friction coefficient. Dimension: Good reach, 1.</p> <p>na: Perturbed friction coefficient, including 100 realizations for each parameter. Dimension: Good reach, 100.</p> <p>b_true: True exponent coefficient. Dimension: Good reach, 1.</p> <p>b: Perturbed exponent coefficient, including 100 realizations for each parameter. Dimension: Good reach, 100.</p>

opencc-by-4.0Aug 2024View details →
zenodo36/100

Data, software, and Figures used in a manuscript submitted to Geoscientific Model Development

<p>Data, software, and Figures used in 'A General Comprehensive Evaluation Method for Cross-Scale Precipitation Forecast' submitted to Geoscientific Model Development.</p>

opencc-by-4.0Oct 2023View details →
zenodo36/100

Multivocal Literature Review Protocol - Investigating the Barriers that Women face in Software Development Teams focusing on the context of Proprietary Software Ecosystems

Open the record for dataset details and reuse information.

opencc-by-4.0Oct 2023View details →
zenodo36/100

BBN designed to develop future land-use scenarios for the Sierra Nevada under different environmental and management conditions

<p>Land-use change (deforestation for crops and pastures, reforestation, firewood removal, etc.) constitutes one of the primary drivers of global change, since human activity is to a greater or lesser degree altering the vegetation cover of the planet. The combined effects of climate change and shifts in land use determine the distribution and structure of the vegetation of the Sierra Nevada, and the associated ecosystem services. The surface cover of tree formations in Sierra Nevada has expanded from 15% to 51.23% over the last 60 years. Similarly, a densification of the scattered tree cover and the natural forests and a decline in the surface area occupied by cultivated fields (from 17.8% to 4.72%) has occurred in the last six decades (Zamora, et al, 2016). Therefore, it is important to ascertain future land use change and its effects on the vegetation cover.&nbsp;</p><p>The main purpose of this model is to facilitate the land-use management of Protected Areas (PAs) based on ecosystem services (ES). A BBN is being designed to develop future land-use scenarios for the Sierra Nevada under different environmental and management conditions. Afterwards, we will implement these scenarios in other ES assessment models. The analysis of ES trade-offs in several scenarios will help managers to predict the state of ES and their relations in the future.</p>

opencc-by-4.0Oct 2023View details →
dryad36/100

Of Mojave milkweed and mirrors: The population genomic structure of a species impacted by solar energy development

<p>A rapid renewable energy transition has facilitated the development of large, ground‐mounted solar energy facilities worldwide. Deserts, and other sensitive aridland ecosystems, are the second most common land‐cover type for solar energy development globally. Thus, it is necessary to understand existing diversity within environmentally sensitive desert plant populations to understand spatiotemporal effects of solar energy siting and design. Overall, few population genomic studies of desert plants exist, and much of their biology is unknown. To help fill this knowledge gap, we sampled Mojave milkweed (<em>Asclepias</em> <em>nyctaginifolia</em>) in and around the Ivanpah Solar Electric Generating Station (ISEGS) in the Mojave Desert of California to understand the species' population structure, standing genetic variation, and how that intersects with solar development. We performed Restriction‐site Associated Sequencing (RADseq) and discovered 9942 single nucleotide polymorphisms (SNPs). Using these data, we found clear population structure over small spatial scales, suggesting each site sampled comprised a genetically distinct population of Mojave milkweed. While mowing, in lieu of blading, the vegetation across the solar energy facility's footprint prevented the immediate loss of the ISEGS Mojave milkweed population, we show that the effects of land‐cover change, especially those impacting desert washes, may impact long‐term genetic diversity and persistence. Potential implications of this include a risk of overall loss of genetic diversity, or even hastened extirpation. These findings highlight the need to consider the genetic diversity of impacted species when predicting the impact and necessary conservation measures of large‐scale land‐cover changes on species with small population sizes.</p>

opencc-zeroOct 2023View details →
dryad36/100

Data from: Hair and plasma cortisol throughout the first three years of development in infant rhesus macaques, Macaca mulatta

<p>Cortisol expression has been demonstrated to have variation across development in rhesus macaques (Macaca mulatta). There exists contradictory evidence for the nature of this change, and age at which it occurs, across biological sample types. Consequently, we lack a cohesive understanding for cortisol concentrations across the development of a major human health translational model. We examined hair cortisol concentrations over the first three years of life for 49 mother-reared infant macaques from mixed-sex outdoor units at the California National Primate Research Center. For 48 of these subjects at infancy, one year, and two years, we obtained plasma cortisol samples for: response to a stressor, adjustment to prolonged stress, and response to dexamethasone injection. Hair cortisol concentrations decreased dramatically between three and ten months, followed by relative stability up to the final sampling event at around 34 months of age. Plasma cortisol showed within-year consistency, and consistency between infancy and year one. We document variability in the infant plasma cortisol samples, especially in percent change between samples one and two. Our plasma cortisol results indicate that infants possess the physiological capacity to effectively inhibit the release of cortisol when stimulated, as effectively as later responses in juveniles. Age-related changes in hair cortisol parallel findings indicating a large decline in the weeks following postparturation.</p>

opencc-zeroNov 2023View details →
zenodo36/100

Data regarding "Development and evaluation of RADA-PDGF2 self-assembling peptide hydrogel for enhanced skin wound healing"

<p>Raw data for data published in Development and evaluation of RADA-PDGF2 self-assembling peptide hydrogel for enhanced skin wound healing, Front. Pharmacol. Sec. Experimental Pharmacology and Drug Discovery Volume 14 - 2023 | <a href="https://doi.org/10.3389/fphar.2023.1293647">doi: 10.3389/fphar.2023.1293647</a></p>

opencc-by-4.0Nov 2023View details →
zenodo36/100

Data for the publication "Developing a climatological simplification of aerosols to enter the cloud microphysics of a global climate model" - part 2

<p>The data is split into two datasets, for each to be smaller than 50 GB.</p>

opencc-by-4.0Nov 2023View details →
zenodo36/100

Timely Dictionary Development: In-person and Virtual Rapid Word Collection for Endangered Indigenous Languages

<p>Timely Dictionary Development: In-person and virtual Rapid Word Collection for endangered Indigenous Languages</p> <p>Dorothea Hoffmann, Wilhelm Meya, Abbie Hantgan-Sonko &amp; Elliot Thornton</p> <p>Presented 5 October 2022 at the Berlin-Brandenburg Academy of Sciences and Humanities Where Do We Need to Go From Here? Language Documentation and Archiving in the International Decade of Indigenous Languages</p>

opencc-by-4.0Oct 2022View details →
dryad36/100

Wind energy development can lead to guild-specific habitat loss in boreal forest bats

<p>Forest management rarely considers protecting bats in Fennoscandian regions although all species rely on forest habitat at some point in their annual cycle. This issue is especially evident as wind parks have increasingly been developed inside Fennoscandian forests, against the advice of international bat conservation guidelines. In this study, we aimed to describe and explain bat community dynamics at a Norwegian wind park located in a boreal forest, especially to understand potential avoidance or attraction effects. The bat community was sampled acoustically and described using foraging guilds (short, medium, and long-range echolocators; SRE, MRE, LRE) as well as behavior (commuting, feeding and social calls). Sampling was undertaken at two locations per turbine: (i) the turbine pad and (ii) a paired natural habitat at ground level, as well as from a meteorological tower. We used a recently developed method for camera trapping nocturnal flying insects synchronously with bat acoustic activity. Our results reveal trends in feeding and general bat activity across foraging guilds in relation to insect availability, habitat type, wind, temperature, and seasonality. We show how seasonal patterns in behavior across guilds were affected by habitat type, temperature, and wind. We found that SRE commuting and especially feeding activity was highest in natural habitats, whereas LRE overall activity at habitats more season dependent. We found that nocturnal insect availability was positively correlated with total bat feeding activity throughout the night. Our results provide evidence for both direct and indirect risks to bat communities by wind parks: SRE bat habitat is lost to wind energy infrastructure and LRE bat may have an increased risk of fatality. Our findings provide important insights on seasonal and spatial variability in bat activity, which can inform standardizing monitoring of bats acoustically in boreal forests, at wind parks, and in combination with non-invasive insect monitoring.</p>

opencc-zeroNov 2023View details →
zenodo36/100

Replication Package: Vulnerably (Mis)Configured? Exploring 10 Years of Developers' Q&As on Stack Overflow

<p><strong>Welcome to the public repository for the additional content of the paper "Vulnerably (Mis)Configured? Exploring 10 Years of Developers' Q&amp;As on Stack Overflow", accepted at the International Working Conference on Variability Modelling of Software-Intensive Systems (VAMOS) 2024.</strong></p><p>This repository provides additional information to the conducted exploratory study on configuration-related vulnerabilities, including the following files:</p><ul><li>README.txt</li><li>LICENSE.txt</li><li>DATASET_CONFIG_VULN_SO.csv: sheet containing data of 651 StackOverflow posts, including additional classifications based on manual analyses and automatic topic modeling</li></ul><p><strong>Instructions for using the dataset</strong></p><ol><li>Download and open the dataset (platform-independent CSV file).</li><li>The dataset includes 16 columns (A – P):<br>- Columns A – J: Original data fetched from the BigQuery Stack Overflow dataset (<i>Question_ID, Year_Asked, Question_Title, Question_Body, Question_Tags, View_Count, Question_Rating, Favorite_Count, Status, Answer_Count</i>)<br>- Columns K – N: Manually extracted data from the Stack Overflow posts (<i>System, Configuration Context, Security Context, Topic</i>)<br>- Column O: Data based on the automated topic modeling (<i>Configuration Topic</i>)<br>- Column P: Additional data extracted from the Stack Overflow posts without further classifications (<i>Additional Comments</i>)</li></ol><p><strong>Requirements</strong></p><ul><li>No requirements</li></ul><p><strong>Further information</strong></p><ol><li>The dataset is based on a search string (SQL query; August 1, 2023) applied on the Google BigQuery Stack Overflow dataset:<i>&nbsp;</i><br><i>("secur*") AND ("vulnerabilit*" OR "weakness*" OR "breach*" OR "exposure*" OR "CVE*" OR "CWE*") AND ("config*")</i></li><li>Originally, the dataset included 1,235 post which were limited by the first and second authors to 651 posts (34 deleted posts, 550 posts out of scope) using the following selection criteria:&nbsp;<br>- The post has been created in the last decade (2013-2022).<br>- The post is still available on the Stack Overflow website.<br>- The post is directly connected to a vulnerability-related issue in the context of configuring.</li><li>Topic modeling algorithm used: Latent Dirichlet Allocation (LDA)<br>- Settings: 200 iterations (coherence value = 0.6 for k = 7 to 11), α = k, β = 0.01</li></ol>

opencc-by-4.0Nov 2023View details →
dryad36/100

Data from: Larval diet and temperature alter mosquito immunity and development: using body size and developmental traits to track carry-over effects on longevity

<p><span><strong>Background</strong>:</span><span> Estimating arbovirus transmission potential requires a mechanistic understanding of how environmental factors influence the expression of adult mosquito traits. While preimaginal exposure to environmental factors can have profound effects on adult traits, tracking and predicting these effects remains challenging. </span></p> <p><span><strong>Methods</strong>:</span><span> Using <em>Aedes albopictus</em> and a structural equation modelling approach, we explored how larval nutrition and temperature jointly affect development rate and success, body size, and whether these metrics capture carry-over effects on adult longevity. Additionally, we investigated how larval diet and temperature affect the baseline expression of ten immune genes. </span></p> <p><span><strong>Results</strong>:</span><span> We found that larval development </span><span>success</span><span> was primarily determined by diet, while temperature and diet both affected development rate, pupal wet weight, and wing length. Effects of diet on both morphometric measures and their relationships to adult longevity were asymmetrical, with wing length having a positive association and pupal weight a negative association. Larval diet indirectly affected adult longevity, and the time to pupation was negatively correlated with longevity. </span><span>The</span><span> expression of </span><span>eight </span><span>immune genes from Toll, </span><span>JAK-STAT, and Imd pathways </span><span>was enhanced in mosquitoes with higher nutrition. </span></p> <p><span><strong>Conclusions</strong>:</span><span> Our results highlight deficiencies from using a single body size measure to capture carry-over effects on adult traits. Further studies of larval development rate under varying environmental conditions and its potential for tracking carry-over effects on vectorial capacity are warranted. </span></p>

opencc-zeroNov 2023View details →
zenodo36/100

A Framework to Promote Diversity & Inclusion in Workforce Development in the Southeast States

<p>The lack of workforce diversity has made it challenging for transportation agencies to &nbsp;</p><p>incorporate resiliency into their long-term plans effectively. This project developed a &nbsp;</p><p>framework for creating an inclusive and functional workforce environment for transportation &nbsp;</p><p>agencies in the southeast region. The project identifies existing gaps, predicts future needs, and &nbsp;</p><p>captures the role transportation agencies, research centers, Departments of Transportations &nbsp;</p><p>(DOTs), and professional organizations can play to recruit, train, and maintain a diverse and &nbsp;</p><p>inclusive workforce. This research will ultimately contribute to creating a resilient &nbsp;</p><p>transportation workforce structure in the southeast region. The goal of this project is to present &nbsp;</p><p>an Equity, Diversity, and Inclusion (EDI) -focused framework for promoting diversity and &nbsp;</p><p>inclusion within the workforce.&nbsp;</p>

opencc-by-4.0Dec 2023View details →
zenodo36/100

Software Development Waste amidst COVID-19 Pandemic: An Industry Study

<p>The dataset is to support the publication "Software Development Waste amidst COVID-19 Pandemic: An Industry Study" in ISEC 2024.&nbsp;</p>

opencc-by-4.0Dec 2023View details →
zenodo36/100

Infographics of six key aspects in the development of citizen science projects

<p>These six infographics describe six key aspects in the development of citizen science projects. The six key ideas are: co-creation, communities, tools and methods, data, ethics and inclusion, and action. Each infographics condensates several ideas and messages in three &nbsp;columns: why is the aspect is important, how can this aspect be further develop and finally a set of practical recommendations.</p> <p>The digital material is also available at the Universitat de Barcelona <a href="https://web.ub.edu/en/web/ciencia-ciutadana/">website</a> on citizen science. The material is being used in certified training activities on citizen science and developed by the <a href="http://www.ub.edu/opensystems/">OpenSystems</a> research group. The first use of this material is being done during a certified training program offered by IDP-ICE UB: Training in citizen science: Introduction and deepening in the development of participatory research projects with social commitment. It had a 10 h duration and it was oriented to a wide audience that mostly include universities staff, civil society organisations representatives, university students, and public administration staff.</p> <p>Infographics created under the CSNOW project with the Citizen Science Work Group of the IDP-ICE UB, coordinated by Josep Perell&oacute; with the support of N&uacute;ria Coll-Bonfill. Translations from Catalan to English have been possible with the support of the TORCH EU project. Design: <a href="https://minimalheroes.tv">Minimal Heroes</a>.</p>

opencc-by-4.0Nov 2023View details →
zenodo36/100

URB937 prevents the development of mechanical allodynia in rats with trigeminal neuralgia

<p>This dataset comprises the findings obtained in the study aimed at investigating the effects of URB937, a peripherally restricted fatty acid amide hydrolase inhibitor, in preventing and abolishing the trigeminal mechanical allodynia developed by rats subjected to chronic constriction injury of the infraorbital nerve (IoN-CCI).</p> <p>&nbsp;</p> <p>In vivo assessments performed in male Sprague-Dawley rats within the preventive and abrogative paradigm:</p> <p>- IoN-CCI model: following anaesthesia, the rat&rsquo;s head was fixed in a stereotaxic frame and a mid-line scalp incision was made, exposing the skull and nasal bone. The edge of the orbit was dissected free, and the orbital contents were deflected with a cotton-tipped wooden rod to give access to the left IoN, which was loosely ligated with two chromic catgut ligatures (5-0) (2 mm apart). The scalp incision was closed us-ing silk sutures (5-0). In sham operated rats, the IoN was exposed using the same procedure, but the nerve was not ligated.</p> <p>- Prevention of mechanical allodynia: IoN-CCI animals were treated with URB937 (1mg/kg, i.p.) or vehicle (10% polyethylene glycol 200, 10% Tween 80 and saline) from day +1 after surgery and then every other day until day +25. The animals were tested with mechanical stimulation test (MST) the day before surgery (for baseline measurement) and on days +5, +12, +18 and +26 after surgery. Sham animals were treated with vehicle and subjected to the same procedure.</p> <p>- Abrogation of mechanical allodynia: IoN-CCI animals were subjected to chronic treatment with URB937 (1mg/kg, i.p.) or vehicle (10% polyethylene glycol 200, 10% Tween 80 and saline) after the complete development of allodynia. The animals underwent the MST the day before surgery (for baseline measurement) and on days +5, +12, +18 and +25 after surgery. On day +25, after MST, rats were treated with URB937 or vehicle and then daily until day +29 (5 total injections). On day +29, animals underwent MST 1 hour after URB937 or vehicle treatment. Sham animals were treated with vehicle and subjected to the same procedure.</p> <p>- Mechanical stimulation test (MST): a graded series of five Von Frey hairs (0.015 g, 0.127 g, 0.217 g, 0.745 g, and 2.150 g) were applied within the IoN territory, near the center of the vibrissal pad. Von Frey hairs were applied in an ascending order of intensity either ipsi- or contralaterally. For each rat, and at every designated time, a mean score for the five von Frey filaments was determined. The final MST responses of each rat are expressed as percentages to their baseline values.</p> <p>Ex vivo assessments performed on samples collected at the end of the last MST:</p> <p>- Gene expression analysis: mRNA expression levels of calcitonin gene-related peptide (CGRP), tumor necrosis factor alpha (TNF-alpha), interleukin (IL)-1beta and IL-10 in the medulla, cervical spinal cord and trigeminal ganglion ipsilateral to IoN-CCI. mRNA levels were measured by rt-PCR. All samples were assayed in triplicate and gene expression levels were calculated according to the &Delta;&Delta;Ct method and expressed as relative quantification.</p> <p>&nbsp;</p> <p>RESULTS:</p> <p>URB937 significantly prevented the development of mechanical allodynia and the IoN-CCI-induced changes in mRNA expression levels of CGRP and cytokines in the evaluated areas. Similarly, treatment with URB937 after allodynia development significantly counteracted the IoN-CCI-induced changes in CGRP and cytokines gene expression; this was not associated with a significant abrogation of the mechanical allodynia.</p>

opencc-by-4.0Jul 2023View details →
dryad36/100

Supporting data for: Development of alternate climate divisions for Colorado based on gridded data

<p>The official climate divisions for the contiguous United States are used for a wide range of purposes, including ongoing climate monitoring, and through NOAA's long-standing nClimDiv dataset. In Colorado, the climate divisions are based around the basins of the large rivers that flow out of the state. However, considering the complex topography and climate of the state, these divisions do not always represent key climate variations and changes. This study builds upon an approach first developed by Wolter and Allured to establish alternate climate divisions that more closely reflect observed climate variability across Colorado. Hierarchical cluster analysis is applied to gridded temperature and precipitation data (NOAA's nClimGrid) from 1950–2021 to identify areas with similar climate variability, then manual inspection is used to establish 11 divisions. These resulting divisions are being used in an updated state-level climate change assessment. The method is flexible and uses open-source tools that could be extended to other regions or datasets.</p>

opencc-zeroDec 2023View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record

ScienceDex for faculty

Your academic CV and NIH biosketch

Make your CV in your school's format and your NIH biosketch from it, then download both as Word files.