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59 results for “Cerebral autoregulation”
Relationship between the autonomic nervous system and cerebral autoregulation during controlled breathing
<h2>Version 3 of the database</h2> <p>The updated version of the database includes autonomic nervous system data (HRV metrics) estimated using the ECG signal.</p> <p>The previous versions of the database included data estimated from non-invasive, photoplethysmography-based ABP signals.</p> <h1>Funding</h1> <p>SONATA 18 UMO-2022/47/D/ST7/00229 National Science Centre, Poland (database 2)</p> <p>SONATA-BIS UMO-2013/10/E/ST7/00117 National Science Centre, Poland (database1)</p> <h1>General information</h1> <p>Two datasets were used in this study.</p> <p>The dataset 1 includes <strong>49 healthy volunteer</strong>s (28 females, 21 males, median age: 23 years, range: 18-31 years) who were measured at the Neuroengineering Laboratory at Wroclaw University of Science and Technology (WUST) between October 2014 and June 2015 (Biomedical Committee Agreement number: KB-170/2014).</p> <p>The dataset 2 includes <strong>12 healthy volunteers</strong> (8 females, 4 males, median age: 25 years, range: 20-26 years) who were prospectively measured at WUST between October 2023 and January 2024 (Biomedical Committee Agreement number: KB-179/2023/N).</p> <h1>Signal recordings description</h1> <ul> <li>ABP was measured non-invasively by a servo-controlled plethysmograph (Finometer MIDI, FMS Medical Systems, Amsterdam, The Netherlands in dataset 1 and Finapres Nova, FMS Medical Systems in dataset 2). The cuff was placed on the middle finger of the left hand and held at the level of the heart.</li> <li>A three-lead surface electrocardiogram (ECG) was used to record the heart's electrical activity</li> <li>CBv was measured in the MCA using transcranial Doppler ultrasonography (Doppler BoxX, DWL, Compumedics Germany GmbH, Singen, Germany in database 1; EMS-9PB, Delica, Shenzhen, China in database 2).</li> <li>Expired end-tidal CO2 (EtCO2), carbon dioxide (CO2) concentration and respiratory rate (RR) were measured via a nasal cannula using a portable capnography monitor (RespSense™, NONIN, Plymouth, USA)</li> <li><strong>Protocol:</strong> After a resting epoch lasting at least 5 minutes (baseline, referred to in the aliases as "B"), a controlled breathing session was initiated. Five-minute recordings were collected at each of the following respiratory rates: 6, 10, or 15 breaths per minute (corresponding to 0.1 Hz, 0.17 Hz, and 0.25 Hz, respectively), guided by a digital metronome (referred to in aliases as "6", "10", "15")</li> </ul> <h1>Data description</h1> <ul> <li>ID</li> <li>Type of database (database 1/database 2)</li> <li>Type of device used for ABP measurement (ECG was measured in the same way in both databases, using a built-in module, attached to photoplethysmography)</li> <li>Metadata including: sex (male M, female F), and age</li> <li>Physiological parameters measured during controlled breathing, including:</li> <ul> <li>end-tidal carbon dioxide: ETCO2</li> <li>Respiratory rate: RR</li> <li>Carbon dioxide concentration: CO2</li> <li>Heart rate: HR</li> <li>Arterial blood pressure: ABP</li> <li>Cerebral blood flow velocity: CBv</li> </ul> <li>Autonomic Nervous System metrics, including:</li> <ul> <li>joint symbolic dynamics, estimated as the relative frequency of baroreflex-like word types (JSD<sub>sym</sub>) and the relative frequency of patterns that are opposed to baroreflex behaviour (JSD<sub>diam</sub>) (Baumert et al., 2015)</li> <li>entropy metrics: MSEn, multiscale entropy; ApEn, approximate entropy; SampEn, sample entropy, FuzzyEn, fuzzy entropy</li> <li>frequency-domain metrics: LFn, HFn, normalized power spectral density of the R-R interval time series in the low-frequency range (LF, 0.04–0.15 Hz) and the high-frequency range (HF, 0.15–0.40 Hz), obtained by dividing the respective power spectra by a total power (TP, 0.04–0.40 Hz); LF/HF; low-to-high frequency ratio; </li> <li>Baroreflex sensitivity estimated using cross-correlation method (xBRS) </li> <li>time-domain metrics: SDNN, standard deviation of the R-R intervals; RMSSD, square root of the mean of the squared successive differences between adjacent R-R intervals; meanNN, mean intervals between normal R-peaks, pNN20 and pNN50, proportion of R-R intervals greater than 20 ms or 50 ms, respectively;</li> </ul> <li>Cerebral autoregulation metrics, including TFA metrics were provided for two frequency ranges: VLF, very low frequency (0.02–0.07 Hz), BF, breathing frequency (determined for each of the participants for spontaneous breathing and 0.10; 0.17; 0.25 Hz±0.02 Hz for controlled breathing); </li> <ul> <li>coherence,</li> <li>phase shift (PS)</li> <li>gain</li> </ul> </ul> <p> </p> <p> </p> <p> </p>
Cerebral Oxygenation and Autoregulation in Preterm Infants
ClinicalTrials.gov study NCT02147769. IPD Sharing: Not stated. Countries: 1. Publications: 6.
Cerebral Autoregulation Monitoring During Cardiac Surgery
ClinicalTrials.gov study NCT00981474. IPD Sharing: NO. Countries: 1. Publications: 32.
Hemodynamic Effects on Cerebral Autoregulation in Acute Stroke
ClinicalTrials.gov study NCT02056821. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of Cardiopulmonary Bypass Flow on Cerebral Autoregulation
ClinicalTrials.gov study NCT05681741. IPD Sharing: NO. Countries: 1. Publications: 0.
Cerebral Autoregulation and COVID-19
ClinicalTrials.gov study NCT04930874. IPD Sharing: NO. Countries: 1. Publications: 17.
Bedside Monitoring to Identify Impaired Cerebral Autoregulation in Women with Postpartum Hypertension
ClinicalTrials.gov study NCT05155852. IPD Sharing: NO. Countries: 1. Publications: 1.
Cerebral Autoregulation in Patients With Epilepsy
ClinicalTrials.gov study NCT02775682. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Monitoring of Cerebral Autoregulation in Pediatric ECMO (ECMOX 1)
ClinicalTrials.gov study NCT04282525. IPD Sharing: NO. Countries: 1. Publications: 2.
Individual Blood Pressure Optimization Based on Cerebral Autoregulation After Implantation of Continuous-flow LVAD
ClinicalTrials.gov study NCT03093012. IPD Sharing: YES. Countries: 1. Publications: 7.
Impact of Personalised Cardiac Anaesthesia and Cerebral Autoregulation on Neurological Outcomes in Patients Undergoing Cardiac Surgery
ClinicalTrials.gov study NCT05595954. IPD Sharing: Not stated. Countries: 2. Publications: 0.
Remote Ischaemic Conditioning in the Older Person and Effects on Dynamic Cerebral Autoregulation
ClinicalTrials.gov study NCT07179887. IPD Sharing: NO. Countries: 1. Publications: 8.
Quantification of Dynamic and Static Cerebral Autoregulation (CA) Under Anaesthesia
ClinicalTrials.gov study NCT03816072. IPD Sharing: NO. Countries: 1. Publications: 1.
The Prediction of Hemorrhage Transformation by Cerebral Autoregulation in AIS Patient After Endovascular Thrombectomy
ClinicalTrials.gov study NCT06361017. IPD Sharing: NO. Countries: 1. Publications: 3.
Noninvasive Monitoring of Cerebral Blood Flow Autoregulation in Patients With Traumatic Brain Injury (TBI)
ClinicalTrials.gov study NCT01605838. IPD Sharing: Not stated. Countries: 1. Publications: 11.
Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury
ClinicalTrials.gov study NCT06480838. IPD Sharing: YES. Countries: 1. Publications: 24.
Cerebral Autoregulation in Patients With Aneurysmal SubArachnoid Haemorrhage
ClinicalTrials.gov study NCT03987139. IPD Sharing: YES. Countries: 1. Publications: 22.
Multimodal Monitoring of Cerebral Autoregulation After Pediatric Brain Injury
ClinicalTrials.gov study NCT04242602. IPD Sharing: NO. Countries: 1. Publications: 22.
Brainstem Grey Matter and Cerebral Autoregulation in Migraine With Aura.
ClinicalTrials.gov study NCT02708797. IPD Sharing: NO. Countries: 1. Publications: 2.
CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State
ClinicalTrials.gov study NCT06133842. IPD Sharing: NO. Countries: 1. Publications: 21.
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