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548 results for “Leukemia stem cells”
Single-cell proteo-transcriptomic profiling reveals altered characteristics of stem and progenitor cells in patients receiving cytoreductive hydroxyurea in early-phase chronic myeloid leukemia
<p>This repository contains CITE-seq data generated from CML stem and progenitor cells before and after hydroxyurea treatment using the BD Rhapsody Single-Cell Analysis System. </p> <p><strong><br>File descriptions:</strong></p> <p>1. RSEC-adjusted UMI count files generated using the BD Rhapsody Targeted Analysis Pipeline (v. 1.10.1):</p> <ul> <li>CartridgeS1_RSEC_MolsPerCell.csv</li> </ul> <p>2. RSEC-adjusted UMI counts for cells remaining after cell quality filtering using SeqGeq software (genes expressed vs library size):</p> <ul> <li>CartridgeS1_RSEC_MolsPerCell_postQC.csv</li> </ul> <p>3. Sample tag (sample of origin) calls for each putative cell, outputted by the BD Rhapsody Targeted Analysis Pipeline (v. 1.10.1). </p> <ul> <li>CartridgeS1_Sample_Tag_Calls.csv</li> </ul> <p> </p>
Supplementary Data for "Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance"
<p><strong>We performed functional genomic profiling of diverse leukemias using label tracing techniques. We identified AML stem cell quiescence is defined by distinct promoter-centered chromatin and gene expression dynamics, and controlled by a novel transcription factor network, which is associated with disease persistence and chemotherapy resistance in multiple patients. </strong></p>
Tacrolimus and Methotrexate With or Without Sirolimus in Preventing Graft-Versus-Host Disease in Young Patients Undergoing Donor Stem Cell Transplant for Acute Lymphoblastic Leukemia in Complete Remis
ClinicalTrials.gov study NCT00382109. IPD Sharing: Not stated. Countries: 3. Publications: 2.
Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia
ClinicalTrials.gov study NCT01904136. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Donor Peripheral Stem Cell Transplant in Treating Patients With Relapsed Acute Myeloid Leukemia
ClinicalTrials.gov study NCT00274846. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Selective T-Cell Depletion to Reduce GVHD (Patients) Receiving Stem Cell Tx to Treat Leukemia, Lymphoma or MDS
ClinicalTrials.gov study NCT00025662. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Safety Study of Oral Azacitidine (CC-486) as Maintenance Therapy After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Sy
ClinicalTrials.gov study NCT01835587. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia
ClinicalTrials.gov study NCT00792948. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Stem Cell Transplantation With NiCord® (Omidubicel) vs Standard UCB in Patients With Leukemia, Lymphoma, and MDS
ClinicalTrials.gov study NCT02730299. IPD Sharing: NO. Countries: 10. Publications: 4.
Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia
ClinicalTrials.gov study NCT00060424. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Fludarabine Phosphate and Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia or Chronic Myelogenous Leukemia That Has
ClinicalTrials.gov study NCT00036738. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Chemotherapy With or Without Imatinib and/or Peripheral Stem Cell Transplant in Acute Lymphoblastic Leukemia
ClinicalTrials.gov study NCT00458848. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Chemotherapy, Imatinib Mesylate, and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
ClinicalTrials.gov study NCT00039377. IPD Sharing: Not stated. Countries: 1. Publications: 2.
A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation From Related or Matched Unrelated Donors in Pediatric Patients With Solid Tumors and Leukemias
ClinicalTrials.gov study NCT01287104. IPD Sharing: NO. Countries: 1. Publications: 1.
Clofarabine and Low-Dose Total-Body Irradiation in Treating Patients With Acute Myeloid Leukemia Undergoing Donor Peripheral Blood Stem Cell Transplant
ClinicalTrials.gov study NCT01252667. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia
ClinicalTrials.gov study NCT00469014. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation
ClinicalTrials.gov study NCT03856216. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transp
ClinicalTrials.gov study NCT01640301. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Chemotherapy, Total-Body Irradiation, Rituximab, and Donor Stem Cell Transplant in Treating Patients With B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
ClinicalTrials.gov study NCT00425802. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lym
ClinicalTrials.gov study NCT00104858. IPD Sharing: Not stated. Countries: 3. Publications: 1.
ScienceDex guides
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International Brain Laboratory public data
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.