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70
datasets available to search
ShareScore release 0.9.0
Dataset results
70 results for “PARP1”
TSG101 Associates with PARP1 and is Essential for PARylation and DNA Damage-induced NF-κB Activation
<p>This dataset contains the raw luciferase assay data generated in the genome-wide siRNA screen.</p>
Expression and purification of PARP1 from Sf9 Insect cells 2019/02/04
<p><strong>Project: </strong>Investigating HTT parylation and PAR-binding in its putative role in DNA damage repair</p> <p><strong>Experiment: </strong>Expression and purification of PARP1 from Sf9 Insect cells</p> <p><strong>Date completed:­ </strong>2019/02/04</p> <p><strong>Rationale: </strong>HTT may be parylated or recognize PAR motifs on other proteins involved in DNA damage repair. To test this hypothesis, the full-length PARP1 cDNA was cloned in to pFBOH-SBP-TEV-LIC, overexpressed in insect cell Sf9 culture and purified. The purified PARP1 protein will be shared with Dr. Tamara Maiuri for her future experiments on the link between HTT protein and parylation. </p>
Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (human)
GEO Series GSE55484. Homo sapiens. 16 samples. Type: Expression profiling by array.
Role of PARP1 in cocaine-related memory retrieval
GEO Series GSE83718. Rattus norvegicus. 5 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity
GEO Series GSE160973. Homo sapiens. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination
GEO Series GSE181933. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors
GEO Series GSE115145. Homo sapiens. 651 samples. Type: Genome variation profiling by SNP array; SNP genotyping by SNP array.
The three-dimensional structure of Epstein-Barr virus genome varies by latency type and is regulated by PARP1 enzymatic activity [RNA-Seq]
GEO Series GSE159836. Homo sapiens. 8 samples. Type: Expression profiling by high throughput sequencing.
PARP1 expression drives the synergy between trabectedin and PARP1 inhibitors
GEO Series GSE77175. Homo sapiens. 8 samples. Type: Genome variation profiling by SNP array.
PARP1- and CTCF-mediated interactions between active and repressed chromatin at the lamina promote oscillating transcription
GEO Series GSE58534. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
PRMT6 and PARP1 sequencing in non-treated MDA-MB-231 cells
GEO Series GSE210947. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
RNA polymerase II and PARP1 shape enhancer-promoter contacts [Micro-C]
GEO Series GSE206131. Homo sapiens; Mus musculus. 51 samples. Type: Other.
Identification of PARP1-RNA binding in-vivo using PAR-CLiP Sequencing
GEO Series GSE95360. Homo sapiens. 1 samples. Type: Other.
Gene expression profilings for prostate cancer cells after inhibition of PARP1 or PARP2 using pharmaceutical or siRNA-based approaches
GEO Series GSE114273. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Global gene expression in response to X rays in mice deficient in Parp1
GEO Series GSE101402. Mus musculus. 24 samples. Type: Expression profiling by array.
PARP1 expression predicts and determines synergy between PARP1 inhibitors and trabectedin.
GEO Series GSE76981. Homo sapiens. 24 samples. Type: Expression profiling by array.
Effect of PARP1 inhibition on transcription high and low PARP activity cell lines
GEO Series GSE58844. Homo sapiens. 12 samples. Type: Expression profiling by array.
Genome-wide profiling of PARP1 reveals an interplay with gene regulatory regions and DNA methylation
GEO Series GSE61744. Homo sapiens. 2 samples. Type: Methylation profiling by array.
Temporal regulation of PARP1 acetylation in tumorigenesis
GEO Series GSE269944. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (mouse)
GEO Series GSE55485. Mus musculus. 12 samples. Type: Expression profiling by array.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.