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26 results for “Steroidal Glycosides”
Data from: "Steroidal glycoside profile differences among primary roots system and adventitious roots in Solanum dulcamara"
<p>The zip-file contains all chromatograms reported in vendor (.D) and open-source (.mzxml) formats.</p>
Raw data and metadata associated with the manuscript: "Organ and ontogeny-specific steroidal glycoside diversity is associated with differential expression of steroidal glycoside pathway genes in two Solanum dulcamara leaf chemotypes"
<p>Raw LC-MS and RT-qPCR data and metadata associated with the manuscript: "Ontogeny and organ-specific steroidal glycoside diversity is associated with differential expression of steroidal glycoside pathway genes in two <em>Solanum dulcamara</em> leaf chemotypes", accepted at Plant Biology.</p>
Fig. 4. Compounds 1, 21 in Six C21 steroidal glycosides from Cynanchum wallichii Wight roots and their multidrug resistance reversal activities
Fig. 4. Compounds 1, 21, and 25 can reverse drug resistance by decreasing P-gp, NF-κB, and c-jun gene and protein expression. (A–C) MDR1, NFκB, and JUN gene expression in MCF-ADR and HepG2-ADM cells following co-treatment with 1, 21, and 25 and Doxorubicin. (D–E) MDR1, NFκB, and Jun protein expression in MCFADR and HepG2-ADM cells treated with 1, 21, and 25 in combination with DOX.
Fig. 3. The C21 in Six C21 steroidal glycosides from Cynanchum wallichii Wight roots and their multidrug resistance reversal activities
Fig. 3. The C21 steroid compounds (1–28) exhibited DOX resistance reversing activity (A) Cell viability following treatment with compounds 1–28. (B) CI value for DOX and the isolated compounds in HepG2/ ADM and MCF7/ADR cells. (C) Intersection diagram for DOX and 50% of the steroid compounds with the highest IC50 values at the same concentration. (D) Molecular docking model findings for the computer simulation of the multidrug resistance-associated protein (P-gp) and the steroid compounds.
Fig. 2 in Six C21 steroidal glycosides from Cynanchum wallichii Wight roots and their multidrug resistance reversal activities
Fig. 2. NF-κB expression in breast cancer and hepatocellular carcinoma Adriamycin-resistant cell lines with increased P-gp expression and significant drug resistance (A) Cell viability in DOX-treated MCF-7 and HepG2 cells and drug-resistant MCF-7/ADR and HepG2/ADM cells. (B–D) Background expression of proteins (P-gp) and genes (MDR1, NFκB, JUN) in DOX-treated MCF-7 and HepG2 cells and in drug-resistant MCF-7/ADR and HepG2/ADM cells.
Fig. 3. Selected 2D in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 3. Selected 2D NMR correlations of compound 6.
Fig. 2. Key HMBC and 1H–1H in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 2. Key HMBC and 1H–1H COSY correlations of compounds 1–5 and 7.
Fig. 1 in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 1. Structures of compounds 1–7 identified from S. delicatula.
Fig. 4 in Seladelicatulasine A-G, C steroidal glycosides with cholinesterase inhibitory activities from Selaginella delicatula
Fig. 4. Lineweavere-Burk plot for the inhibitin of AChE by compound 5.
Fig. 2. Key 2D NMR correlations for 1 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 2. Key 2D NMR correlations for 1 and the ester fragments.
Fig. 1 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 1. Chemical structures of 1–21 from M. tenacissima.
Fig. 5 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 5. ECD and UV spectra of 4.
Fig. 3 in Steroid glycosides from the roots of Marsdenia tenacissima
Fig. 3. Plausible mechanism of the intramolecular transacetylation of 10/11 and 12/13.
Fig. 1 in Six C21 steroidal glycosides from Cynanchum wallichii Wight roots and their multidrug resistance reversal activities
Fig. 1. Structures of compounds Isolated from Cynanchum wallichii wight roots.
Fig. 2 in Cytotoxic steroidal glycosides from Polygonatum odoratum (Mill.) Druce
Fig. 2. Key HMBC (
Fig. 3 in Cytotoxic steroidal glycosides from Polygonatum odoratum (Mill.) Druce
Fig. 3. Key NOESY () correlations of aglycone moiety of compounds 1, 2, 4.
Fig. 2 in Steroidal glycosides from the Vietnamese cultivar Cordyline fruticosa "Fairchild red"
Fig. 2. Structures of the known compounds 13 and 14.
Fig. 1 in Steroidal glycosides from the Vietnamese cultivar Cordyline fruticosa "Fairchild red"
Fig. 1. Structures of the previously undescribed compounds 1–12.
Fig. 11. PSVII induces BxPC-3 in Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis
Fig. 11. PSVII induces BxPC-3 cells pyroptosis by activating caspase-1.
Fig. 2. Key 1H–1H in Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis
Fig. 2. Key 1H–1H COSY, HMBC, and NOESY correlations of compound 1.
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