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7 results for “Zanthoxylum nitidum”
Fig. 4 in Undescribed isoquinolines from Zanthoxylum nitidum and their antiproliferative effects against human cancer cell lines
Fig. 4. Chiral HPLC-UV and chiral HPLC-CD profiles of 1–4, experimental ECD spectra and the calculated ECD spectra (1–4), respectively.
Fig. 5 in Undescribed isoquinolines from Zanthoxylum nitidum and their antiproliferative effects against human cancer cell lines
Fig. 5. Effects of compound 2b on the cell viability, colony formation and cell cycle distribution in the A549 cells. (A) Cells were treated with compound 2b (0.05, 0.1, or 0.2 μM) for 48 h, and then morphological changes were detected by phase-contrast microscopy (200 × magnification). (B) Cells were treated with 2b (0.05, 0.1, or 0.2 μM) for 14 days. Colony formation was subsequently observed under light microscopy (40 × magnification). (C) Cells were treated with 2b for 24 h, and then the cell cycle distribution was analyzed by flow cytometry. (D) Cells were treated with compound 2b for 24 h, and then the protein expressions of Cyclin A, Cyclin B1, Cdc25C and p21 were detected by western blot analysis. Relative intensity of indicated proteins was quantified using NIH ImageJ software (bottom panel).
Fig. 7 in Undescribed isoquinolines from Zanthoxylum nitidum and their antiproliferative effects against human cancer cell lines
Fig. 7. Effects of compound 2b on the Wnt/β-catenin signaling pathways in the A549 cells. Cells were treated with compound 2b for 24 h, and then the indicated protein expressions were detected using western blot analysis. Relative intensity of indicated proteins was quantified using NIH ImageJ software (bar graph).
Fig. 6 in Undescribed isoquinolines from Zanthoxylum nitidum and their antiproliferative effects against human cancer cell lines
Fig. 6. Effects of 2b on the induction of apoptosis, cell migration, and expressions of EMT biomarker proteins in the A549 cells. (A) Cells were seeded, treated with 2b for 48 h, collected, and stained with annexin V-FITC/PI to detect the apoptotic cell population using flow cytometry. The percentages of each cell population (live cell, early apoptosis, late apoptosis, and necrosis) were quantified and presented as a bar graph. (B) Cells were treated with compound 2b for 48 h, the expressions of caspases and Bcl-2 were analyzed by western blotting. Relative intensity of indicated proteins was quantified using NIH ImageJ software (bar graph, bottom panel). (C) Cells were treated with 2b for 24 h or 48 h, and then the cell migration was detected by wound healing assay and photographed under microscope (40 × magnification). (D) Cells were treated with 2b for 24 h, and then the expressions of EMT biomarkers were analyzed by western blotting. Relative intensity of indicated proteins was quantified using NIH ImageJ software (bar graph, bottom panel).
Fig. 3. X in Undescribed isoquinolines from Zanthoxylum nitidum and their antiproliferative effects against human cancer cell lines
Fig. 3. X-ray ORTEP drawing of 1 and 23.
A high-quality chromosome-level genome assembly of the traditional Chinese medicinal herb Zanthoxylum nitidum
GEO Series GSE281536. Zanthoxylum nitidum. 21 samples. Type: Expression profiling by high throughput sequencing.
Effect of Zanthoxylum Nitidum Tincture for Paronychia Caused by Afatinib
ClinicalTrials.gov study NCT03908892. IPD Sharing: NO. Countries: 1. Publications: 0.
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