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2,368 results for “arthroplasty”
Reverse Total Shoulder Arthroplasty Alters Humerothoracic, Scapulothoracic, and Glenohumeral Motion During Weighted Scaption
<p>This dataset contains scapula and humerus kinematics from 10 healthy subjects, and 10 subjects post-operative to reverse total shoulder arthroplasty, performing scapular plane abduction (scaption) with and without a 2.2 kg (5 lb) handheld weight. The humerus and scapula were imaged at 100 Hz using a biplane fluoroscopy system. 3D models of the humerus and scapula were constructed from each subject’s CT scan. Model-based markerless tracking ascertained the 3D position and orientation of each bone model by semi-automatically aligning digitally reconstructed radiographs against each frame of the biplane fluoroscopy recordings. The kinematics of the bones are presented relative to each subject's torso. These data are available for download to aid researchers and clinicians in characterizing non-pathologic and reverse total shoulder arthroplasty motion during scapular plane abduction with and without a 5 lb handheld weight.</p>
Dataset of The Relationship Between Postoperative Opioid Analgesia and Sleep Apnea Severity in Patients Undergoing Hip Arthroplasty: A Randomized, Controlled, Triple-Blinded Trial
<p>This the dataset related to the article entitled "he Relationship Between Postoperative Opioid Analgesia and Sleep Apnea Severity in Patients Undergoing Hip Arthroplasty: A Randomized, Controlled, Triple-Blinded Trial".</p> <p>Purpose: Residual postoperative pain after hip arthroplasty is usually treated with oral opioids. While classic opioids are associated with respiratory depression and worsening of sleep apnea, tramadol has been reported to preserve respiratory function. However, this has not been investigated in a prospective trial using respiratory polygraphy. This randomized controlled triple-blinded trial tested the hypothesis that postoperative treatment with oral opioids such as oxycodone would increase sleep apnea severity, measured with a respiratory polygraphy, compared with oral tramadol.<br> Patients and Methods: Sixty patients undergoing hip arthroplasty under spinal anesthesia with 15 mg isobaric bupivacaine 0.5% were randomized to receive postoperative pain treatment with either oral oxycodone (controlled-release 10 mg every 12 hours and immediate-release 5 mg every 4 hours as needed) or oral tramadol (controlled-release 100 mg every 8 hours and immediate-release 50 mg every 4 hours as needed). Respiratory polygraphy was performed on the first postoperative night. The primary outcome was the apnea-hypopnea index in the supine position. Secondary outcomes included the oxygen desaturation index, postoperative pain scores and intravenous morphine consumption.<br> Results: Mean supine apnea-hypopnea index on postoperative night 1 was 11.3 events.h−1 (95% confidence interval, 4.8–17.7) in the oxycodone group and 10.7 (4.6–16.8) events.h−1 in the tramadol group (p=0.89). There were no significant differences between the oxycodone and tramadol groups with respect to any secondary sleep-related or pain-related outcomes.<br> Conclusion: Oral oxycodone did not increase sleep apnea severity measured using respiratory polygraphy compared with oral tramadol on the first postoperative night after hip arthroplasty.</p>
Early Virtual-Reality-Based Home Rehabilitation after Total Hip Arthroplasty: A Randomized Controlled Trial
<p>The benefits of early virtual-reality-based home rehabilitation following total hip arthroplasty (THA) have not yet been assessed. The aim of this randomized controlled study was to compare the efficacy of early rehabilitation via the Virtual Reality Rehabilitation System (VRRS) versus traditional rehabilitation in improving functional outcomes after THA. Subjects were randomized either to an experimental (VRRS; n = 21) or a control group (control; n = 22). All participants were invited to perform a daily home exercise program for rehabilitation after THA with different administration methods—namely, an illustrated booklet for the control group and a tablet with wearable sensors for the VRRS group. The primary outcome was the hip disability (HOOS JR). Secondary outcomes were the level of independence and the degree of global perceived effect of the rehabilitation program (GPE). Outcomes were measured before surgery (T0) and at the 4th (T1), 7th (T2), and 15th (T3) day after surgery. Mixed-model ANOVA showed no significant group effect but a significant effect of time for all variables (<em>p </em>< 0.001); no differences were observed in HOOS JR between VRRS and the control at T0, T1, T2, or T3. Further, no differences in the level of independence were found between VRRS and the control, whereas the GPE was higher at T3 in VRSS compared to the control (4.76 ± 0.43 vs. 3.96 ± 0.65; <em>p </em>< 0.001). Virtual-reality-based home rehabilitation resulted in similar improvements in functional outcomes with a better GPE compared to the traditional rehabilitation program following THA. The application of new technologies could offer novel possibilities for service delivery in rehabilitation.</p>
Data/Code: Objective monitoring of functional recovery after total knee and hip arthroplasty using sensor-derived gait measures
<p>Abstract</p> <p>Background: Inertial sensors hold the promise to objectively measure functional recovery after total knee (TKA) and hip arthroplasty (THA), but their value in addition to patient-reported outcome measures (PROMs) has yet to be demonstrated. This study investigated recovery of gait after TKA and THA using inertial sensors, and compared results to recovery of self-reported scores of pain and function.</p> <p>Methods: PROMs and gait parameters were assessed before and at two and fifteen months after TKA (n=24) and THA (n=24). Gait parameters were compared with healthy individuals (n=27) of similar age. Gait data were collected using inertial sensors on the feet, lower back, and trunk. Participants walked for two minutes back and forth over a 6m walkway with 180° turns. PROMs were obtained using the Knee Injury and Osteoarthritis Outcome Scores and Hip Disability and Osteoarthritis Outcome Score.</p> <p>Results: Gait parameters recovered to the level of healthy controls after both TKA and THA. Early improvements were found in gait-related trunk kinematics, while spatiotemporal gait parameters mainly improved between two and fifteen months after TKA and THA. Compared to the large and early improvements found in of PROMs, these gait parameters showed a different trajectory, with a marked discordance between the outcome of both methods at two months post-operatively.</p> <p>Conclusion: Sensor-derived gait parameters were responsive to TKA and THA, showing different recovery trajectories for spatiotemporal gait parameters and gait-related trunk kinematics. Fifteen months after TKA and THA, there were no remaining gait differences with respect to healthy controls. Given the discordance in recovery trajectories between gait parameters and PROMs, sensor-derived gait parameters seem to carry relevant information for evaluation of physical function that is not captured by self-reported scores.</p>
Dronabinol in Total Knee Arthroplasty (TKA)
ClinicalTrials.gov study NCT04734080. IPD Sharing: YES. Countries: 1. Publications: 0.
A Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty
ClinicalTrials.gov study NCT01181167. IPD Sharing: YES. Countries: 1. Publications: 1.
A Phase 2b Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Hip Arthroplasty
ClinicalTrials.gov study NCT01203098. IPD Sharing: YES. Countries: 2. Publications: 1.
A Phase 3 Study of DU-176b, Prevention of Venous Thromboembolism in Patients After Total Knee Arthroplasty
ClinicalTrials.gov study NCT01181102. IPD Sharing: YES. Countries: 2. Publications: 3.
On the Consequences of Intraoperative Release vs Over-tensioning of the Posterior Cruciate Ligament in Total Knee Arthroplasty
<p>This dataset contains data derived from musculoskeletal modeling to investigate the effects of posterior cruciate ligament (PCL) tensioning in total knee arthroplasty (TKA). The findings indicate minimal differences in knee kinematics and kinetics for PCL releases of up to 10%, regardless of implant conformity. However, over-tensioning the PCL significantly increases joint overload, potentially compromising implant longevity. These results suggest that, in cases where precise intraoperative PCL tensioning cannot be reliably achieved, a slightly looser PCL may be preferable to mitigate complications associated with excessive tension.</p> <p>The structure of the data is detailed in the accompanying <code>Data Description.txt</code> file, which is provided alongside the dataset (<code>JRSI_Data.mat</code>).</p>
Distal Femoral Landmarks from Skeletons with Total Knee Arthroplasty
<p>This dataset contains raw 3D landmark coordinates for the articular surface of the distal femur. The sample consists of 43 modern adult human skeletons from the University of Tennessee Donated Skeletal Collection. 12 of the skeletons received unilateral total knee arthroplasty (TKA) during life due to osteoarthritis; landmarks for these individuals were taken on the non-replaced (healthy) antimere. The remaining 31 individuals serve as controls, having received no knee replacement during life and showing no signs of joint degenerative disease. </p>
How do patients sleep after orthopedic surgery? Changes in objective sleep parameters and pain in hospitalized patients undergoing hip and knee arthroplasty
<p><strong>Aim.</strong> Sleep impairment after hip and knee arthroplasty is multifactorial and still poorly understood and post-operative pain is a potential cause of sleep deprivation or disturbances. The aim of this study was to assess actigraphy-based sleep characteristics and pain scores in patients undergoing knee or hip joint replacement and hospitalized for ten days after surgery. <strong>Methods.</strong> In this observational cohort study, n=20 subjects (11 males and 9 females; age: 64.0±10.39 years old) completed a daily sleep diary and wore the Actiwatch 2 actigraph (Philips Respironics, Portland, OR) to record sleep parameters for 11 consecutive days, starting the day before surgery and ending the 10<sup>th</sup> day after surgery. Subjective scores of pain, by a visual analog scale (VAS), were constantly monitored for the entire experimental protocol. The following evaluation time-points have been considered for the analysis: pre-surgery (PRE), the first (POST1), the fourth (POST4) and the tenth day (POST10) after surgery. A repeated-measures one-way analysis of variance followed by the Tukey-Kramer post hoc tests, or the equivalent nonparametric Friedman test followed by the Dunn’s multiple comparisons, was applied to test differences in sleep and pain among time-points. Test for correlation between mean VAS score and the sleep parameters at each post-operative time point were performed using Pearson’s method. <strong>Results.</strong> Sleep quantity and timing parameters did not differ from PRE to POST10, during the hospitalization. On the contrary, Sleep Efficiency (p=0.006; η<sup>2</sup><sub>p</sub>=0.45, large), Sleep Latency (p=0.039; η<sup>2</sup><sub>p</sub>=0.37, large), Wake After Sleep Onset (p=0.042; η<sup>2</sup><sub>p</sub>=0.34, large), Immobility Time (p=0.005; η<sup>2</sup><sub>p</sub>=0.47, large) and Fragmentation Index (p=0.016; η<sup>2</sup><sub>p</sub>=0.36, large) displayed significant differences. In detail, Sleep Efficiency and Immobility Time significantly decreased at POST1 compared to PRE by 10.8% (p=0.003; ES: 0.9, moderate) and 9.4% (p=0.005; ES: 0.86, moderate) respectively. Overall, all sleep quality parameters showed a trend of constant improvement from POST1 to POST10. VAS scores were higher in the 1<sup>st</sup> day post-surgery (4.58 ± 2.46; p=0.0011 and ES: 1.40, large) compared to POST10 (1.68 ± 1.58) and in POST4 (3.85 ± 2.31) compared to POST10 (-2.18; p=0.0087 and ES: 1.09, moderate). During time, mean VAS showed significant negative correlations with mean Sleep Efficiency (r = -0.71; p=0.021) and mean Immobility Time (r = - 0.83; p=0.003) and a significant positive correlation with Fragmentation Index (r = 0.70; p=0.023), highlighting that high scores of pain were associated with lower overall sleep quality. <strong>Conclusion.</strong> Sleep quantity and timing parameters were stable during the entire hospitalization whereas sleep quality parameters significantly worsened the 1<sup>st</sup> night after surgery compared to the pre-surgery night and, overall, these parameters showed a trend of constant improvement until discharge. Pain scores were at the highest level the 1<sup>st</sup> day after surgery and at the lowest level before discharge with a negative correlation between pain and sleep quality parameters during time. The present study confirms the important impact of surgery on sleep parameters, especially on the first few post-operative days.</p>
Prospective Low Dose CT for Total Shoulder Arthroplasty/Reverse Shoulder Arthroplasty
ClinicalTrials.gov study NCT05350319. IPD Sharing: NO. Countries: 1. Publications: 6.
Meloxicam for Pain Management After Total Joint Arthroplasty (TJA)
ClinicalTrials.gov study NCT05291598. IPD Sharing: NO. Countries: 1. Publications: 1.
Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)
ClinicalTrials.gov study NCT01780389. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Opioid-Free Shoulder Arthroplasty
ClinicalTrials.gov study NCT03540030. IPD Sharing: NO. Countries: 1. Publications: 27.
Melatonin Use After Primary Total Joint Arthroplasty
ClinicalTrials.gov study NCT04795336. IPD Sharing: YES. Countries: 1. Publications: 0.
Knee Arthroplasty Pain Coping Skills Training (KASTPain): A Randomized Trial
ClinicalTrials.gov study NCT01620983. IPD Sharing: YES. Countries: 1. Publications: 7.
Use of Real Time Instrumentation (RTI) in Total Shoulder Arthroplasty
ClinicalTrials.gov study NCT01905241. IPD Sharing: NO. Countries: 1. Publications: 1.
Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
ClinicalTrials.gov study NCT07350252. IPD Sharing: NO. Countries: 1. Publications: 10.
HAKA: Routine Follow-Up at 1 Year After Hip- or Knee Arthroplasty: Wasting Resources or Appropriate Healthcare?
ClinicalTrials.gov study NCT06971757. IPD Sharing: YES. Countries: 1. Publications: 0.
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.