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105 results for “biopsy sampling”
Skin-blubber biopsy samples and associated demographic data collected from cetaceans encountered along the Western Antarctic Peninsula (WAP), 2010 – 2024
Baleen whale populations in the Southern Ocean are recovering after intense commercial whaling in the 20th century. Along the Western Antarctic Peninsula (WAP), this recovery is occurring in one of the planet's most rapidly changing marine ecosystems. Understanding how climate-driven changes influence the population dynamics of whales in this region is critical for understanding what conservation and management actions must be prioritized to maintain the structure and function of this marine ecosystem. To begin understanding the dynamics of whale recovery under continued environmental change, we need to study these whales' demography and population dynamics. As part of our annual sampling surveys for cetaceans along the WAP through the PAL LTER program, we actively collect remote non-lethal skin-blubber biopsy samples and have developed one of the most extensive tissue archives in the Southern Ocean. With these samples, we conduct a series of demographic and physiological measurements. Using the skin portion of the biopsy sample, we isolate nuclear and mitochondrial DNA (mtDNA) to develop a DNA profile for each sample, including genetic sex, a microsatellite genotype, and a mtDNA haplotype. These profiles are used to compare sex ratios of the population, determine individual recaptures through genotype analysis, and better understand population mixing. Using the blubber portion of the biopsy sample, we isolate endocrine markers (e.g., progesterone and cortisol) to monitor population pregnancy rates and stress levels. This data represents some of the first non-lethal quantitative observations of the demography and population dynamics of recovering whale populations in the Antarctic and provides a critical reference point for future work as the Antarctic climate continues to change and populations continue to recover from whaling.
DEcancer: Proteomics Datasets of Liquid Biopsy Samples
<p>Two datasets used to build the DEcancer pipelines from open access data. The tables in the cancerseek folder are uploaded for convenience and can also be found from the supplementary data of <a href="https://doi.org/10.1016/j.isci.2019.04.035">Early Cancer Detection from Multianalyte Blood Test Results</a> paper. The nanoparticles dataset is processed with the Perseus software on the <a href="http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD017052">original data</a> from Blume <em>et al's</em> Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona. These are distinct datasets in that the nanoparticles is a cohort of patients from a high dimensional, low sample size proteomics dataset.</p>
Data from: A comparison of non-destructive visceral swab and tissue biopsy sampling methods for genotyping-by-sequencing in the freshwater mussel Fusconaia askewi
<p>Limiting harm to organisms via genetic sampling is an important consideration for rare species. Nondestructive sampling techniques have been developed to address this issue in freshwater mussels. Two methods, visceral swabbing and tissue biopsies, have proven to be effective for DNA sampling, though it is unclear as to which method is preferable for genotyping-by-sequencing (GBS). Tissue biopsies may cause undue stress and damage to organisms, while visceral swabbing potentially reduces the chance of such harm. Our study compared the efficacy of these two DNA sampling methods for generating GBS data for the Unionid freshwater mussel, Texas Pigtoe (<em>Fusconaia askewi</em>). Our results find both methods generate quality sequence data, though some considerations are in order. Tissue biopsies produced significantly higher DNA concentrations and larger numbers of reads when compared to swabs, though there was no significant association between starting DNA concentration and number of reads generated. Swabbing produced greater sequence depth (more reads per sequence) while tissue biopsies revealed greater coverage across the genome (at lower sequence depth). Patterns of genomic variation as characterized in principal component analyses were similar regardless of the sampling method, suggesting that the less invasive swabbing is a viable option for producing quality GBS data in these organisms.</p>
Data from: A comparison of non-destructive visceral swab and tissue biopsy sampling methods for genotyping-by-sequencing in the freshwater mussel Fusconaia askewi
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Sample Collection Study in Patients With Suspected Melanoma Utilizing DermTech's Non-invasive Adhesive Patch Biopsy Kits
ClinicalTrials.gov study NCT04550000. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Evaluation of Patients With Esophageal and Foregut Disorders With WATS (Wide Area Transepithelial Sample With 3-Dimensional Computer-Assisted Analysis) vs. 4-Quadrant Forceps Biopsy
ClinicalTrials.gov study NCT03859557. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease
ClinicalTrials.gov study NCT00026884. IPD Sharing: YES. Countries: 1. Publications: 1.
PSA Levels and Biopsy Samples After Implant Radiation and Hormone Therapy in Patients With Stage I or Stage II Prostate Cancer
ClinicalTrials.gov study NCT00898326. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Skin Immunity Sample Collection Involving Blisters and Biopsies
ClinicalTrials.gov study NCT03921515. IPD Sharing: Not stated. Countries: 1. Publications: 3.
A Sample Collection Study Utilizing DermTech's Non-invasive Adhesive Patch Biopsy Kits
ClinicalTrials.gov study NCT04668846. IPD Sharing: NO. Countries: 1. Publications: 1.
Sentinel Node Biopsy and Axillary Sampling in Operable Breast Cancer
ClinicalTrials.gov study NCT00128362. IPD Sharing: Not stated. Countries: 1. Publications: 2.
Evaluation of See.d as an Automated Blood Sample Preparator for Multiple Liquid Biopsy Applications
ClinicalTrials.gov study NCT06097156. IPD Sharing: NO. Countries: 1. Publications: 6.
Endoscopic Ultrasound-guided Fine-needle Biopsy for Tissue Sampling of Biliary Strictures: a Multicenter Prospective Study
ClinicalTrials.gov study NCT06614452. IPD Sharing: UNDECIDED. Countries: 1. Publications: 10.
Assessing the Histological Quality of Biopsy Samples Obtained With Multibite Forceps
ClinicalTrials.gov study NCT05227079. IPD Sharing: NO. Countries: 1. Publications: 5.
Comparison of Sample Biopsy Using Scalpel or Er:YAG Laser
ClinicalTrials.gov study NCT03638973. IPD Sharing: NO. Countries: 1. Publications: 1.
Collection of Blood, Bone Marrow, Leukapheresis, and Tissue Biopsy Samples From Patients and Their Family Members for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases Laboratory Re
ClinicalTrials.gov study NCT01200823. IPD Sharing: Not stated. Countries: 1. Publications: 4.
22G-Adapt Needle Biopsy Versus Fine-needle Aspiration in Endoscopic Ultrasound-guided Sampling of Solid Lesions
ClinicalTrials.gov study NCT06563232. IPD Sharing: Not stated. Countries: 1. Publications: 7.
Comparison of Endobronchial Ultrasound-Guided Biopsy Using Fine Needle Aspiration Versus Fine Needle Capillary Sampling
ClinicalTrials.gov study NCT00886847. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Concordance of Molecular Classification Based on Fine Needle Biopsy (FNB) and Surgical Samples
ClinicalTrials.gov study NCT06133374. IPD Sharing: NO. Countries: 1. Publications: 24.
Comparing Biopsy Needles for Endoscopic Ultrasound Guided Samples for Pancreatic Masses
ClinicalTrials.gov study NCT02911974. IPD Sharing: NO. Countries: 1. Publications: 5.
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.