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Dataset results
178 results for “malaria vaccine”
Targeting Plasmodium falciparum chondroitin sulfate a ligand: A highly conserved malaria antigen with potential for pregnancy-associated malaria vaccine development
<p>The dataset represents the details of sera samples collected from participants recruited for a longitudinal study. The sera was used for ELISA <em>in vitro</em> assays. The immunoreactivity of PfCSA-L antigen was assessed with the utilization of the gravidity status of the study participants. The antigen is used by the <em>plasmodium falciparum</em> parasite to adhere to the placenta during pregnancy and causes challenges both to the mother and her fetus.</p> <h5>Variables</h5> <ul> <li> <p>Sample_ID - This is the coded details of the study participant.</p> </li> <li> <p>Mean*od <em>_1st_visit, Mean</em>od <em>_2nd_visit, and Mean</em>od *_3rd_visit - These represent the mean reactivity values for antibody (IgG) to PfCSA-L antigen for antenatal visits 1,2 and 3 respectively.</p> </li> <li> <p>Gravida - Refers to the total number of confirmed pregnancies a female has had, regardless of the outcome of the pregnancy.</p> </li> <li> <p>PCR_Results - these are molecular diagnostic results for <em>Plasmodium falciparum</em> to assess whether the study participants were positive or negative for this species. positive = 1 and negative = 0</p> </li> <li> <p>Gestation..weeks - Refers to how far along the pregnancy is, from the first day of the woman's last menstrual cycle to the delivery</p> </li> <li> <p>Newborn outcome - Describes the health status of the childlren when they were born</p> </li> <li> <p>Gravida_class - Describes the different classes of gravida, such that primigravida means single pregnancy, secundigravida-second pregnancy, and tertigravida-third pregnancy</p> </li> <li> <p>Age - Describes the age of the participants recruited for the study</p> </li> <li> <p>HB_level - Describes the amount of hemoglobin in whole blood expressed in grams per deciliter (g/dl) during<br>enrolment</p> </li> <li> <p>Type of delivery - A spontaneous vaginal delivery (SVD) describes when a pregnant female goes into labor without the use of drugs or techniques to induce labor, and delivers her baby in the normal manner, without forceps, vacuum extraction, or a cesarean section (cs)</p> </li> <li> <p>N/A - Missing values for different variables</p> </li> </ul>
Perennial malaria chemoprevention with and without malaria vaccination to reduce malaria burden in young children: a modeling analysis
<p>Simulation input and processed output files accompanying publication on "Perennial malaria chemoprevention with and without malaria vaccination to reduce malaria burden in young children: a modelling analysis"</p> <p>https://malariajournal.biomedcentral.com/articles/10.1186/s12936-023-04564-9 </p>
Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children.
ClinicalTrials.gov study NCT00380393. IPD Sharing: YES. Countries: 2. Publications: 7.
Safety and Immunogenicity of Plant-Derived Pfs25 VLP-FhCMB Malaria Transmission Blocking Vaccine in Healthy Adults
ClinicalTrials.gov study NCT02013687. IPD Sharing: UNDECIDED. Countries: 1. Publications: 1.
Safety, Immunogenicity and Efficacy of the Blood-stage Plasmodium Vivax Malaria Vaccine Candidate PvDBPII in Matrix M1
ClinicalTrials.gov study NCT04201431. IPD Sharing: NO. Countries: 1. Publications: 1.
Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian Children
ClinicalTrials.gov study NCT00360230. IPD Sharing: YES. Countries: 1. Publications: 2.
Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian Infants
ClinicalTrials.gov study NCT00289185. IPD Sharing: YES. Countries: 1. Publications: 2.
Safety, Immunogenicity, and Protective Efficacy of Radiation Attenuated Plasmodium Falciparum NF54 Sporozoites (PfSPZ Vaccine) During Malaria Transmission Season in Healthy African Adult Women of Chil
ClinicalTrials.gov study NCT03989102. IPD Sharing: NO. Countries: 1. Publications: 7.
Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in Africa
ClinicalTrials.gov study NCT00866619. IPD Sharing: YES. Countries: 7. Publications: 22.
A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, Administered With and Without Matrix-M1
ClinicalTrials.gov study NCT02572388. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI Regimen
ClinicalTrials.gov study NCT00436007. IPD Sharing: YES. Countries: 3. Publications: 4.
Study to Assess the Vaccine Efficacy Against Malaria Infection, in Children Immunized With the Primary and Yearly Booster of the RTS,S/AS01E Vaccine, as Part of Their Participation in the Malaria-094
ClinicalTrials.gov study NCT03281291. IPD Sharing: NO. Countries: 2. Publications: 1.
A Challenge Study to Assess the Safety, Immunogenicity and Efficacy of a Malaria Vaccine Candidate
ClinicalTrials.gov study NCT02927145. IPD Sharing: UNDECIDED. Countries: 1. Publications: 4.
Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults.
ClinicalTrials.gov study NCT00197054. IPD Sharing: YES. Countries: 1. Publications: 1.
Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial Therapy
ClinicalTrials.gov study NCT04661579. IPD Sharing: NO. Countries: 1. Publications: 17.
Study of the Transmission-Blocking Vaccine Pfs230D1-EPA/Matrix-M Against Malaria in Adults in Mali
ClinicalTrials.gov study NCT05135273. IPD Sharing: NO. Countries: 1. Publications: 4.
Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and Children
ClinicalTrials.gov study NCT01148459. IPD Sharing: YES. Countries: 1. Publications: 1.
Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine
ClinicalTrials.gov study NCT00223990. IPD Sharing: Not stated. Countries: 1. Publications: 3.
Safety Study of Candidate Malaria Vaccine FMP1/AS02A in Healthy Adults in Bandiagara, Mali
ClinicalTrials.gov study NCT00308061. IPD Sharing: NO. Countries: 1. Publications: 3.
A Study to Assess the Safety and Immunogenicity of the Malaria Vaccine, R21, With Matrix-M1 Adjuvant
ClinicalTrials.gov study NCT02925403. IPD Sharing: Not stated. Countries: 1. Publications: 38.
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OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.