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78 results for “syphilis”
Graphs of data for elderly individuals (aged 60 to 120 years) with syphilis in Brazil
<p>A set of data graphs containing informations on elderly people with syphilis in Brazil, aged between 60-120 years with syphilis in Brazil, aged between 60-120 years and contains spreadsheet results of trend analysis of acquired syphilis, by regions of Brazil, in the period 2010-2020, referring to the article entitled "<strong>ACQUIRED SYPHILIS IN OLDER PEOPLE IN BRAZIL FROM 2010-2020".<br><br><br></strong>The dataset used to plot the graphs can be found at: <a href="https://doi.org/10.5281/zenodo.10086131">https://doi.org/10.5281/zenodo.10086131</a></p>
Massive Health Education through Technological Mediation: analyzes and impacts on the syphilis epidemic in Brazil
<p><strong>Repository </strong></p> <p><strong>Dataset name: </strong>avasus_syphilis_trail_dataset.csv </p> <p><strong>Version:</strong> 1.0 </p> <p><strong>Dataset period: </strong>05/12/2016 - 01/14/2022 </p> <p><strong>Dataset Characteristics: </strong>Multivalued </p> <p><strong>Number of Instances: </strong>177732<strong> </strong></p> <p><strong>Number of Attributes: </strong>16 </p> <p><strong>Missing Values: </strong>Yes </p> <p><strong>Area(s): </strong>Health and education </p> <p><strong>Sources: </strong></p> <ul> <li> <p>Virtual Learning Environment of the Brazilian Health System (AVASUS) (Brasil, 2022a); </p> </li> <li> <p>Brazilian Occupational Classification (CBO) (Brasil, 2022b);</p> </li> <li> <p>National Registry of Health Establishments (CNES) (Brasil, 2022c).</p> </li> </ul> <p><strong>Description:</strong> The data contained in the avasus_syphilis_trail_dataset.csv dataset (see Table 1) originate from AVASUS users who have taken a course on the “Syphilis and other STI” learning path. This dataset provides elemental data to analyze the impact and reach of the trails and the profile of their participants.</p> <p><strong>Table 1: </strong>Description of Dataset Features. </p> <table> <tbody> <tr> <td> <p><strong>Attributes </strong></p> </td> <td> <p><strong>Description </strong></p> </td> <td> <p><strong>datatype </strong></p> </td> <td> <p><strong>Value</strong></p> </td> <td> <p><strong>Source</strong></p> </td> </tr> <tr> <td> <p><strong>user_id</strong></p> </td> <td> <p>Unique identifier of the user (anonymously).</p> </td> <td> <p>Numerical. </p> </td> <td> <p>Randomly generated integer.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>user_gender</strong></p> </td> <td> <p>Gender of the user. </p> </td> <td> <p>Categorical. </p> </td> <td> <p>Feminino / Masculino / Não Informado. (In English: Female, Male or Uninformed)</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>user_occupation</strong></p> </td> <td> <p>User occupation</p> </td> <td> <p>Categorical. </p> </td> <td> <p>Text coded according to the Brazilian Classification of Occupations or “Indivíduo sem afiliação formal.” (In English “Individual without formal affiliation.”)</p> </td> <td> <p>CNES.</p> </td> </tr> <tr> <td> <p><strong>user_cnes</strong></p> </td> <td> <p>The CNES code refers to the health establishment where the user works.</p> </td> <td> <p>Numerical.</p> </td> <td> <p>CNES Code or NaN.</p> </td> <td> <p>CNES.</p> </td> </tr> <tr> <td> <p><strong>user_level_attention</strong></p> </td> <td> <p>Identification of the health care network level for which the user works.</p> </td> <td> <p>Categorical.</p> </td> <td> <p>“ATENCAO PRIMARIA”,</p> <p>“MEDIA COMPLEXIDADE”, </p> <p>“ALTA COMPLEXIDADE”, </p> <p>and their possible combinations.</p> <p>(In English "PRIMARY HEALTH CARE", "SECONDARY HEALTH CARE" AND "TERTIARY HEALTH CARE")</p> <p>Or NaN.</p> </td> <td> <p>CNES.</p> </td> </tr> <tr> <td> <p><strong>user_region</strong></p> </td> <td> <p>Brazilian region in which the user resides.</p> </td> <td> <p>Categorical. </p> </td> <td> <p>Brazilian region according to IBGE: Norte, Nordeste, Centro-Oeste, Sudeste or Sul (In English North, Northeast, Midwest, Southeast or South). Other options: “Exterior” or “Não Informado” (In English: Outside or Not informed).</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>course_id</strong></p> </td> <td> <p>Unique identifier of the course performed by the avasus user.</p> </td> <td> <p>Numerical. </p> </td> <td> <p>Code list according to AVASUS.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>course_name</strong></p> </td> <td> <p>Name of the course taken by the avasus user.</p> </td> <td> <p>Categorical.</p> </td> <td> <p>Course name according to AVASUS.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>course_workload</strong></p> </td> <td> <p>Course timetable.</p> </td> <td> <p>Numerical.</p> </td> <td> <p>Range from 0 to 120.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>course_creation_date</strong></p> </td> <td> <p>Course creation date.</p> </td> <td> <p>Date.</p> </td> <td> <p>“YYYY-MM-DD” or NaN.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>enrollment_id</strong></p> </td> <td> <p>Unique identification of the enrollment carried out by the student in some course of the trail.</p> </td> <td> <p>Numerical. </p> </td> <td> <p>Randomly generated single integer.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>enrollment_creation</strong></p> </td> <td> <p>Date the student registered.</p> </td> <td> <p>Date.</p> </td> <td> <p>“YYYY-MM-DD” or NaN.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>enrollment_completion_date</strong></p> </td> <td> <p>Date the student completed the course.</p> </td> <td> <p>Date.</p> </td> <td> <p>“YYYY-MM-DD” or NaN.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>enrollment_current_progress</strong></p> </td> <td> <p>Student progress regarding course completion.</p> </td> <td> <p>Numerical.</p> </td> <td> <p>Range from 0 to 100.</p> <br> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>enrollment_text_evaluation</strong></p> </td> <td> <p>Comment made by the student about the course.</p> </td> <td> <p>Categorial. </p> </td> <td> <p>Free text or NaN.</p> </td> <td> <p>AVASUS.</p> </td> </tr> <tr> <td> <p><strong>enrollment_course_evaluation</strong></p> </td> <td> <p>A score given to the course by the participant.</p> </td> <td> <p>Numerical.</p> </td> <td> <p>0, 1, 2, 3, 4, 5 or NaN.</p> </td> <td> <p>AVASUS.</p> </td> </tr> </tbody> </table> <p><br> <br> <br> </p> <p><strong>References </strong></p> <p>[1] Brasil (2022a). Ambiente virtual de aprendizagem do sus - avasus. atenção à saúde da pessoa privada de liberdade Available from: https://avasus.ufrn.br/local/avasplugin/cursos/curso.php?id=114 . </p> <p>[2] Brasil (2022b). Classificação brasileira de ocupações - CBO. Available from: http://www.mtecbo.gov.br/cbosite/pages/home.jsf . </p> <p>[3] Brasil (2022c). Cadastro nacional de estabelecimentos de saúde - CNES. Available from: http://cnes.datasus.gov.br/ .</p> <p><strong>Article: </strong>Massive Health Education with Technological Mediation: analyzes and impacts on the syphilis epidemic in Brazil</p>
Doubts about the diagnosis and treatment of syphilis in pregnancy among primary care professionals in a telehealth service
<div> <div> <div> <div>This cross-sectional study aims to describe doubts regarding the diagnosis and treatment of syphilis in pregnancy among primary care professionals in a telehealth service. All teleconsultations (TCs) offered through TelessaúdeRS-UFRGS to primary health care (PHC) services in a state in southern Brazil involving syphilis in pregnancy were included. A total of 356 (TCs) were analyzed.</div> <div> </div> </div> </div> </div> <div> <div> <div> <div>The main doubts about syphilis during pregnancy raised by primary care professionals were related to the need for retreatment (35%), diagnostic definition (23%), and initial treatment (16%). In addition, 95% of TCs were suitable for diagnosing and treating syphilis based on the Brazilian Ministry of Health guidelines. This study suggests that TCs can identify failures in the diagnosis and treatment of public health problems and support decision-making in PHC involving syphilis in pregnancy.</div> </div> </div> </div>
Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection
ClinicalTrials.gov study NCT03637660. IPD Sharing: Not stated. Countries: 1. Publications: 4.
Cefixime for Alternative Syphilis Treatment
ClinicalTrials.gov study NCT03660488. IPD Sharing: NO. Countries: 1. Publications: 1.
Doubts about the diagnosis and treatment of syphilis in pregnancy among primary care professionals in a telehealth service
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Data from: Sensitivity and specificity of point-of-care rapid combination syphilis-HIV-HCV tests
Background: New rapid point-of-care (POC) tests are being developed that would offer the opportunity to increase screening and treatment of several infections, including syphilis. This study evaluated three of these new rapid POC tests at a site in Southern California. Methods: Participants were recruited from a testing center in Long Beach, California. A whole blood specimen was used to evaluate the performance of the Dual Path Platform (DPP) Syphilis Screen & Confirm, DPP HIV-Syphilis, and DPP HIV-HCV-Syphilis rapid tests. The gold-standard comparisons were Treponema pallidum passive particle agglutination (TPPA), rapid plasma reagin (RPR), HCV enzyme immunoassay (EIA), and HIV-1/2 EIA. Results: A total of 948 whole blood specimens were analyzed in this study. The sensitivity of the HIV tests ranged from 95.7–100% and the specificity was 99.7–100%. The sensitivity and specificity of the HCV test were 91.8% and 99.3%, respectively. The treponemal-test sensitivity when compared to TPPA ranged from 44.0–52.7% and specificity was 98.7–99.6%. The non-treponemal test sensitivity and specificity when compared to RPR was 47.8% and 98.9%, respectively. The sensitivity of the Screen & Confirm test improved to 90.0% when cases who were both treponemal and nontreponemal positive were compared to TPPA+/RPR ≥1:8. Conclusions: The HIV and HCV on the multi-infection tests showed good performance, but the treponemal and nontreponemal tests had low sensitivity. These results could be due to a low prevalence of active syphilis in the sample population because the sensitivity improved when the gold standard was limited to those more likely to be active cases. Further evaluation of the new syphilis POC tests is required before implementation into testing programs.
Information of indentified metabolites in metabolomic analysis and summary of the major mass-spectrometry-based studies performed on the syphilis patients or neurosyphilis patients to date
<p>Supplementary Table S1. Information of indentified metabolites in metabolomic analysis. <br> Supplementary Table S2. Summary of the major mass-spectrometry-based studies performed on the syphilis patients or neurosyphilis patients to date. Table includes details about the numbers of sample, the analysis method, and the type of mass spectrometer used and biomarkers identified in previous study.eng</p>
Trial Evaluating the Clinical Efficacy of Cefixime for Treatment of Early Syphilis in Non-pregnant Women
ClinicalTrials.gov study NCT03752112. IPD Sharing: YES. Countries: 1. Publications: 13.
Syphilis Treatment of Partners Trial
ClinicalTrials.gov study NCT02262390. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Dual Rapid HIV & Syphilis Tests in Zambia
ClinicalTrials.gov study NCT02445846. IPD Sharing: Not stated. Countries: 1. Publications: 10.
Tenofovir/Emtricitabine With Doxycycline for Combination HIV and Syphilis Pre-exposure Prophylaxis in HIV-negative MSM
ClinicalTrials.gov study NCT02844634. IPD Sharing: NO. Countries: 1. Publications: 2.
A Cross-sectional Investigational Study to Evaluate the Sensitivity, Specificity, and Utility of the MedMira Inc. Multiplo® Complete Syphilis (TP/nTP) Antibody Test (POCT) to Diagnose Infectious Syphi
ClinicalTrials.gov study NCT06586905. IPD Sharing: NO. Countries: 1. Publications: 1.
Feasibility and Acceptability of Point of Care Rapid Syphilis Testing Among Patients Seeking Family Planning Services in Hawai'i
ClinicalTrials.gov study NCT07358949. IPD Sharing: NO. Countries: 1. Publications: 13.
Alternative Antibiotics for Syphilis
ClinicalTrials.gov study NCT05069974. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Azithromycin/Bicillin Syphilis
ClinicalTrials.gov study NCT00031499. IPD Sharing: Not stated. Countries: 2. Publications: 2.
Oral Doxycycline for the Prevention of Syphilis in Men Who Have Sex with Men (DaDHS)
ClinicalTrials.gov study NCT02864550. IPD Sharing: NO. Countries: 1. Publications: 24.
Congenital Syphilis in Switzerland
ClinicalTrials.gov study NCT05975502. IPD Sharing: NO. Countries: 1. Publications: 4.
Preventing Congenital Syphilis
ClinicalTrials.gov study NCT02353117. IPD Sharing: NO. Countries: 4. Publications: 1.
Syphilis Response to Higher Penicillin Dosage: The 2.4 Versus 7.2 Study
ClinicalTrials.gov study NCT02611765. IPD Sharing: Not stated. Countries: 0. Publications: 1.
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