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NIH funding notice PA-12-284

Exploratory/Developmental Bioengineering Research Grants (EBRG) [R21]

Closed on November 20, 2015.

Posted
September 11, 2012
Close date
November 20, 2015
Activity codes
R21
Institutes taking part
NIBIB, NCI, NHLBI, NIAAA, NIAMS, NICHD, NIDCR, NIDA, NIEHS, NINDS, ORWH

Read the notice on Grants.gov ยท NIH Guide page

The notices it replaced

  1. Reissues: PA-10-010 Exploratory/Developmental Bioengineering Research Grants (EBRG) [R21]
  2. 2 steps back: PA-06-418 Exploratory/Developmental Bioengineering Research Grants(EBRG) [R21]
  3. 3 steps back: PA-03-058

Replaced by PA-16-040.

Who won it before

189 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $40,746,160 in first-year total cost, median $216,465.

Most frequent study sections

  1. Bioengineering, Technology and Surgical Sciences Study Section[BTSS]22
  2. Biomedical Imaging Technology A Study Section[BMIT-A]13
  3. Nanotechnology Study Section[NANO]12
  4. Medical Imaging Study Section[MEDI]10
  5. Bioengineering of Neuroscience, Vision and Low Vision Technologies Study Section[BNVT]8

Most frequent institutions

  1. UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN8
  2. CASE WESTERN RESERVE UNIVERSITY7
  3. UNIVERSITY OF PITTSBURGH AT PITTSBURGH7
  4. STANFORD UNIVERSITY5
  5. UNIVERSITY OF WISCONSIN-MADISON5
Competing awards under PA-12-284 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2016Advanced Ventricular Assist Device with Pulse Augmentation and Automatic Regurgitant Flow Shutoff1R21HL133871-01FUKAMACHI, KIYOTAKACLEVELAND CLINIC LERNER COM-CWRU, OH$315,578BTSS
2016Microdroplet Transporter Protein Assays1R21EB022206-01FARIS, GREGORY WSRI INTERNATIONAL, CA$306,112ZRG1
2016Determining the Biomechanical and Biological Response of Stretched Skin1R21EB021590-01A1GOSAIN, ARUN KLURIE CHILDREN'S HOSPITAL OF CHICAGO, IL$289,809ZRG1
2016Development of Small Molecule Inhibitors of IL-18 to Prevent Intimal Hyperplasia1R21HL133821-01PRADHAN-NABZDYK, LEENASUN, LIJUNBETH ISRAEL DEACONESS MEDICAL CENTER, MA$259,500BTSS
2016Computerized Visualization and Prediction of Coronary Artery Ischemia1R21HL132277-01KUCEYESKI, AMY FRANCESMIN, JAMES KWEILL MEDICAL COLL OF CORNELL UNIV, NY$254,250BMIT
2016MIF20-loaded nanoparticles for TBI treatment1R21NS095147-01DE LANEROLLE, NIHAL CZHOU, JIANGBINGYALE UNIVERSITY, CT$250,750BNVT
2016Advanced Image-Based Approach to Assess How Fibrillar Collagen Modulates Airway Reactivity1R21HL129468-01A1PARAMESWARAN, HARIKRISHNANBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$246,450LCMI
2016Dissecting the origins of fetal hemoglobin modulation of sickle cell vaso-occlusion1R21HL130818-01WOOD, DAVID KEVINUNIVERSITY OF MINNESOTA, MN$242,670ISD
2016Development of a novel cell-based immune therapy using Nanoparticles and natural IgM-producing phagocytic B cells1R21CA205415-01ZHONG, XUEMEIBOSTON MEDICAL CENTER, MA$241,061CII
2016Rapid micro-patterned stretching platform to study cell behaviors during atherosclerosis1R21EB022748-01HAYWARD, RYAN CHRISTOPHERPEYTON, SHELLY R.UNIVERSITY OF MASSACHUSETTS AMHERST, MA$239,250BMBI
2016Abeta-Targeted Fluorinated Liposomes for 19F MRI Detection of Abeta Pathologies in APP/PSEN1 Mice1R21EB020153-01A1TANIFUM, ERICBAYLOR COLLEGE OF MEDICINE, TX$237,750CMIP
2016Validating engineered hiPSC-derived cardiomyocytes as model cells1R21HL130993-01PRUITT, BETH LSTANFORD UNIVERSITY, CA$236,819BMBI
2016Synthetic substrates for the expansion and differentiation of hPSC-derived NPCs1R21EB020767-01A1BRAFMAN, DAVID AARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$235,952BTSS
2016Simultaneous imaging of myocardial blood flow and glucose metabolism using dynamic 18F-FDG PET1R21HL131385-01WANG, GUOBAOUNIVERSITY OF CALIFORNIA AT DAVIS, CA$234,875BMIT
2016Imaging nanophysical properties of actively transporting bronchial mucus1R21HL130901-01A1OLDENBURG, AMY LUNIV OF NORTH CAROLINA CHAPEL HILL, NC$234,634BMIT
2016Producing Nitric Oxide by Pulsed Electrical Discharge in Air for Inhalation Therapy1R21HL130956-01A1YU, BINGLANMASSACHUSETTS GENERAL HOSPITAL, MA$234,514BTSS
2016Computational design of Cas9-based molecular imaging reagents1R21EB021453-01A1HUANG, BOKORTEMME, TANJAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$231,996ZRG1
2016High Resolution and Functional MRI Assessment of Intracranial Atherosclerotic Plaque1R21HL130969-01ANSARI, SAMEER ANORTHWESTERN UNIVERSITY AT CHICAGO, IL$231,750ZRG1
2016An inducible protein knockout strategy based on an orthogonal, ligand-activated E3 ubiquitin ligase1R21EB020898-01A1XU, WENQINGUNIVERSITY OF WASHINGTON, WA$231,500MSFA
2016Engineered CARs Targeting FVIII-specific T and B Cells1R21HL127495-01A1SCOTT, DAVID WILLIAMHENRY M. JACKSON FDN FOR THE ADV MIL/MED, MD$231,385HT
2016Lymphatic contribution to progressive peripheral vascular disease and ulceration1R21HL132598-01RASMUSSEN, JOHN CHARLESSEVICK, EVA M.UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$231,000ZRG1
20164D MR Imaging of Flow and Hemodynamics in Aortic Stenosis1R21HL132263-01A1AMINI, AMIR AUNIVERSITY OF LOUISVILLE, KY$231,000MEDI
2016Vascularized cell-based device for restoring physiological homeostasis1R21EB022185-01BOYD, NOLAN LEEUNIVERSITY OF LOUISVILLE, KY$228,593BTSS
2016Central Nervous System Tissue Organogenesis via Precise Growth Factor Tethering1R21NS096571-01LEIPZIG, NIC DUNIVERSITY OF AKRON, OH$228,000BTSS
2016Multimodal (PET/MR/NIR) imaging supported drug delivery in inflammatory diseases1R21EB023104-01ANDERSON, CAROLYN J.JANJIC, JELENA MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$228,000ZRG1
2016Altered Neutrophil Function in Ventricular Assist Devices1R21HL132286-01SCHMIDTKE, DAVID WUNIVERSITY OF TEXAS DALLAS, TX$223,395BTSS
2016A Computational Model-Enhanced Approach for Tumor Localization During Lumpectomy1R21EB022380-01MESZOELY, INGRID MMIGA, MICHAEL IANVANDERBILT UNIVERSITY, TN$221,820ZRG1
2016A Novel Optogenetic Tool for Precise Mitochondrial Control1R21HL127599-01A1ZHOU, LUFANGUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$221,350MIM
2016Endotypes of thrombocytopenia in the critically ill1R21HL133891-01CLERMONT, GILLESPARKER, ROBERT S.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$217,444ZRG1
2016Bioprinted Vascularized Tissue Constructs1R21AR070408-01BUTCHER, JONATHAN TALBOTCORNELL UNIVERSITY, NY$216,728MTE
2016An objective noninvasive single-cell method to identify HSC differentiation stage1R21HL132642-01A1KRAFT, MARY LUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$216,465EBIT
2016Quantitative Cardiac MRI for Detection of Subclinical Cardiotoxicity in Breast Cancer1R21HL129224-01A1NEZAFAT, REZABETH ISRAEL DEACONESS MEDICAL CENTER, MA$216,250MEDI
2016Monitoring contractile forces during airway constriction1R21HL123522-01A1KRISHNAN, RAMASWAMYBETH ISRAEL DEACONESS MEDICAL CENTER, MA$216,250RIBT
2016Oxygen-rich perfusate that is compatible with optical assessments of myocardial physiology1R21HL132618-01A1KAY, MATTHEW W.GEORGE WASHINGTON UNIVERSITY, DC$215,343ZRG1
2016Protoacoustics - Clinical based range verification for Cancer Treatment1R21CA205063-01A1AVERY, STEPHENUNIVERSITY OF PENNSYLVANIA, PA$214,807BMIT
2016Disambiguating coma etiologies by assessing the lability of EEG dynamics1R21NS096590-01A1CHING, SHINUNGKUMMER, TERRANCE TWASHINGTON UNIVERSITY, MO$213,000NOIT
2016Quantitative imaging biomarkers of radiation-induced bone loss in radiotherapy patients1R21CA208821-01MORRIS, CAROLZBIJEWSKI, WOJCIECH BARTOSZJOHNS HOPKINS UNIVERSITY, MD$211,410ZRG1
2016Biomechanical study on aortic-mitral coupling in transcatheter aortic valve replacement1R21HL127570-01A1SUN, WEIGEORGIA INSTITUTE OF TECHNOLOGY, GA$210,763BTSS
2016Integrated drug-in-cell therapy of in-stent restenosis1R21HL131016-01A1CHORNY, MICHAELCHILDREN'S HOSP OF PHILADELPHIA, PA$210,000NANO
2016Nanoscale Encapsulation for Fragment Based Drug Discovery1R21CA206958-01WAND, A. JOSHUAUNIVERSITY OF PENNSYLVANIA, PA$209,670BBM
2016Matrix remodeling in microfluidic co-culture1R21HL132256-01TSCHUMPERLIN, DANIEL J.MAYO CLINIC ROCHESTER, MN$209,160RIBT
2016Multifunctional Nanoparticles Containing sRAGE Potentiated Bioactive Peptides for Wound Healing1R21EB021570-01A1BERTHIAUME, FRANCOISYARMUSH, MARTIN LRUTGERS, THE STATE UNIV OF N.J., NJ$208,351MTE
2016Noninvasive real-time intracardiac pressure measurements using subharmonic ultrasound1R21HL130899-01DAVE, JAYDEVTHOMAS JEFFERSON UNIVERSITY, PA$205,790MEDI
2016Exosome analysis of drug-resistant cancer cells' response to nanoparticle therapy1R21CA190024-01A1LIU, XUEWUMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$205,559NANO
2016Pulmonary Hypertension Associated with Sickle Cell Disease1R21HL129047-01A1CHESLER, NAOMI CUNIVERSITY OF WISCONSIN-MADISON, WI$203,000BTSS
2016Effects of fluid shear stress on circulating tumor cells1R21CA196202-01A1HENRY, MICHAEL DUNIVERSITY OF IOWA, IA$198,360TPM
2016Novel Ultrashort Echo Time Sequences for Brain MRI1R21NS089004-01A1LARSON, PEDER ERIC ZUFALLUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$198,125NOIT
2016Magnetic Resonance Fingerprinting Assessments of Lung Disease1R21HL130839-01A1DARRAH, REBECCA JFLASK, CHRISTOPHER ACASE WESTERN RESERVE UNIVERSITY, OH$198,125BMIT
2016Single-Cell Stethoscopes for Functional Cardiac Cell Assessment and Sorting1R21HL127655-01A1MELOSH, NICHOLAS ASTANFORD UNIVERSITY, CA$197,500ISD
2016Intervertebral Disc Mechanics Measured by dualMRI In Vivo1R21AR066665-01A1NEU, COREY PUNIVERSITY OF COLORADO, CO$195,659MTE
2016Development of a Liposomal Nanostimulator to Improve Stem Cell-Based Revascularization Therapies1R21HL131469-01A1KONG, HYUNJOONUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$194,473NANO
2016Ultrasound stimulation of the baroreflex1R21HL132257-01YEN, JESSE T-PUNIVERSITY OF SOUTHERN CALIFORNIA, CA$193,900BTSS
2016RFID based Wireless System for Self-powered Implantable Pediatric Cardiac Sensors1R21HL127657-01A1WEN, XUEJUNVIRGINIA COMMONWEALTH UNIVERSITY, VA$193,843BTSS
2016PGD: A shape memory degradable polymer for transcatheter atrial septal defect closure1R21HL126004-01A1BOCKS, MARTINHOLLISTER, SCOTT JUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$193,750BTSS
2016Aortic Plaques and Stroke: Cardiovascular Therapy of Retrograde Embolization Risk1R21HL132357-01MARKL, MICHAELNORTHWESTERN UNIVERSITY AT CHICAGO, IL$193,125HM
2016An Autologous, Culture-Free, Adipose Cell-Based Tissue Engineered Vascular Graft1R21HL130784-01VORP, DAVID ALANUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$191,792BMBI
2016Oral Gene Delivery to Improve Iron Overload Disorders1R21EB023025-01AMIJI, MANSOOR M.KIM, JONGHANNORTHEASTERN UNIVERSITY, MA$190,400GDD
2016Targeting Triple Negative Breast Cancer Using Nanoparticles Loaded with the Anti-Cancer Drug Aminoflavone1R21CA196653-01A1GONG, SHAOQIN -XU, WEIUNIVERSITY OF WISCONSIN-MADISON, WI$182,144ZRG1
2016Developing a strategy to identify & validate pharmacodynamic kinase inhibitor biomarkers1R21CA199042-01A1BIEBERICH, CHARLES J.UNIVERSITY OF MARYLAND BALTIMORE COUNTY, MD$178,103CBSS
2016Nanoparticle Remodeling of Pulmonary Junctions1R21HL129115-01A1MURPHY, CATHERINE J.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$177,941LIRR
2016Imaging Tumor Associated Macrophages in Bone Sarcomas1R21CA190196-01A1DALDRUP-LINK, HEIKE ELIZABETHSTANFORD UNIVERSITY, CA$171,839ZRG1
2016Macro-vasculature surrounding pulmonary nodules as a sign of malignancy1R21CA197493-01A1PU, JIANTAOUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$167,475ZRG1
2016Exploiting Altered Porphyrin Synthesis for Metabolic Imaging of Glioblastoma1R21CA202694-01A1KAO, JOSEPH PAO YUNGMAYER, DIRKUNIVERSITY OF MARYLAND BALTIMORE, MD$167,475CMIP
2016Impact of soluble and physical stimuli on tumor angiogenesis and drug sensitivity1R21CA202040-01KREEGER, PAMELA KMASTERS, KRISTYN SUNIVERSITY OF WISCONSIN-MADISON, WI$166,388TME
2016Bioorthogonal labeling of extracellular matrix assembly1R21AR069248-01A1CALVE, SARAHPURDUE UNIVERSITY, IN$160,387MTE
2015Portable Low Field Magnetic Resonance Device for Acute Lung Injury1R21HL124440-01A1PATZ, SAMUELBRIGHAM AND WOMEN'S HOSPITAL, MA$274,394MEDI
2015Regional Measurement of Alveolar Partial Pressure of Oxygen with HPXe MRI.1R21HL125999-01A1MURADYAN, IGABRIGHAM AND WOMEN'S HOSPITAL, MA$266,063ZRG1
2015High-Speed fMRI of Resting State Connectivity1R21EB018494-01A1POSSE, STEFANUNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM$263,786BMIT
2015MRI Characterization of Arrhythmogenic Scar in Ventricular Tachycardia1R21HL127650-01ANTER, ELADNEZAFAT, REZABETH ISRAEL DEACONESS MEDICAL CENTER, MA$261,000ESTA
2015Engineered Tissue for Biomechanical Phenotyping of Cardiomyopathy Patients1R21HL126025-01CAMPBELL, STUART GYALE UNIVERSITY, CT$249,750CCHF
2015Pulmonary arterial endothelial stiffness and shear-stress induced signaling1R21HL126040-01A1SUKI, BELABOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$245,550RIBT
2015Computational Classification of Human Stem Cell-Derived Cardiomyocytes1R21HL122881-01A1TUNG, LESLIEVIDAL, RENEJOHNS HOPKINS UNIVERSITY, MD$243,000BDMA
2015Lipid Nanoparticles for Targeted Delivery of Enhanced Costimulation Blockade1R21HL127355-01RAIMONDI, GIORGIOJOHNS HOPKINS UNIVERSITY, MD$243,000NANO
2015MMP-targeted viral gene delivery vectors for treatment of infarcted heart1R21HL126053-01A1SUH, JUNGHAERICE UNIVERSITY, TX$240,150GDD
2015NOVEL SYNTHETIC SDG TO TREAT TRAUMA-INDUCED INFLAMMATION1R21AT008291-01A1CHRISTOFIDOU-SOLOMIDOU, MELPOWINKELSTEIN, BETH AUNIVERSITY OF PENNSYLVANIA, PA$240,000NOMD
2015An evaluation of a novel technology to assess neonatal jaundice1R21HD080768-01A1TAYLOR, JAMES AUNIVERSITY OF WASHINGTON, WA$238,630PN
2015Fully optical high throughput screening platform for drug induced arrhythmias1R21HL123012-01A1LAURITA, KENNETHCASE WESTERN RESERVE UNIVERSITY, OH$237,750BMIT
2015Xe129 MRI of the Lung: A New Technology to Assess Treatment for COPD1R21HL129112-01QING, KUNUNIVERSITY OF VIRGINIA, VA$237,000ZRG1
2015Self-replicating RNA-nanoplexes for programming monocytes to regenerate the heart1R21HL126082-01A1NGUYEN, JULIANESTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$236,008GDD
2015Optimizing Nanopore Protein Interactions1R21EB019232-01A1ERVIN, ERICELECTRONIC BIOSCIENCES, INC., CA$234,992NANO
2015Machine learning with generative mixture models for fetal monitoring1R21HD080025-01A1DJURIC, PETAR MQUIRK, J GERALDSTATE UNIVERSITY NEW YORK STONY BROOK, NY$234,571ZRG1
2015Cardiomyocyte-derived Venous Assist Device: Aiding peripheral blood flow1R21HL122882-01A1SARVAZYAN, NARINEGEORGE WASHINGTON UNIVERSITY, DC$233,838BMBI
2015Nanoparticle Transport as a function of Physiologic and Hyperthermic Conditions in a 3D Vascularized Microfluidic Tumor Platform1R21EB019646-01RYLANDER, MARISSA NICHOLEVLACHOS, PAVLOS PUNIVERSITY OF TEXAS AT AUSTIN, TX$233,531BMBI
2015Imaging regional transit time and pulmonary vascular resistance in the human lung1R21HL122753-01A1HOPKINS, SUSAN RUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$232,500ZRG1
2015Photostable Multiplexing NanoAssays for Real-Time Study of Embryonic Stem Cells1R21HL127580-01XU, X. NANCYOLD DOMINION UNIVERSITY, VA$232,500NANO
2015Systemic Inflammatory Response: The Effects of blood-air Interface after Cardiopulmonary Bypass1R21HL125961-01A1HAFT, JONATHANUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$232,500BTSS
2015Are 3T MRI Exams Safe For Patients with Pacemakers and ICDs?1R21HL127433-01ENNIS, DANIEL BUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$231,000MEDI
2015Detection and Grading of Fatty and Fibrotic Liver Using Quantitative Ultrasound1R21EB020766-01OELZE, MICHAEL L.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$229,061MEDI
2015Oxygen Microbubble Peritoneal Ventilation Treatment for Acute Respiratory Distress Syndrome1R21HL129144-01TERRY, BENJAMINUNIVERSITY OF NEBRASKA LINCOLN, NE$228,258SAT
2015Stimulated emission reduced fluorescence (SERF) for breaking and extending the fundamental imaging-depth of two photon microscopy1R21EB020073-01MIN, WEICOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$228,000BMIT
2015Ultra-high Resolution 3D MR Spectroscopic Imaging1R21EB021013-01LIANG, ZHI-PEIUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$227,872BMIT
2015Turn the heat on: High resolution fluorescence imaging via temperature modulation1R21CA191389-01A1GULSEN, GULTEKINUNIVERSITY OF CALIFORNIA-IRVINE, CA$227,276BMIT
2015Dynamic force control of cardiac ablation catheters1R21HL126081-01PARK, YONG-LAECARNEGIE-MELLON UNIVERSITY, PA$226,813BTSS
2015Development of large diameter biodegradable stents for congenital heart disease1R21HL129095-01NUGENT, ALAN WILLIAMUT SOUTHWESTERN MEDICAL CENTER, TX$226,147BTSS
2015Identification of AF Ablation Targets via a Steerable Actuated Catheter1R21EB019161-01A1DESAI, JAYDEV P.UNIV OF MARYLAND, COLLEGE PARK, MD$222,800BMIT
2015Second Harmonic Generation analysis of the ECM in idiopathic pulmonary fibrosis1R21HL126190-01A1CAMPAGNOLA, PAUL JSANDBO, NATHAN KSINGH, VIKASUNIVERSITY OF WISCONSIN-MADISON, WI$218,370EBIT
2015Dynamic MRI Image Analysis for Studying Thoracic Insufficiency Syndrome1R21HL124462-01A1CAMPBELL, ROBERT MURRAYUDUPA, JAYARAM KUNIVERSITY OF PENNSYLVANIA, PA$217,708ZRG1
2015SPARSITY-DRIVEN IDEAL OBSERVERS FOR GUIDING IMAGING HARDWARE OPTIMIZATION1R21EB020168-01A1ANASTASIO, MARK AWASHINGTON UNIVERSITY, MO$213,000BMIT
2015Biomolecule-Directed Assembly for Enhancing Near IR Energy Transfer Processes in Theranostics1R21EB020911-01CHA, JENNIFER NGOODWIN, ANDREW PPARK, WOUNJHANGUNIVERSITY OF COLORADO, CO$211,076NANO
2015Projection Imaging of Peripheral Vascular Calcifications1R21HL126015-01A1EDELMAN, ROBERT R.ENDEAVOR HEALTH CLINICAL OPERATIONS, IL$208,745ZRG1
2015Outside-In Regenerative Therapy for Abdominal Aortic Aneurysm1R21HL129066-01CURCI, JOHN AVORP, DAVID ALANUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$206,747BTSS
2015Free-standing nanowire transistor bio-probes for intracellular and implanted recording1R21EB020822-01QING, QUANARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$204,127BNVT
2015Personalized RAD52-dependent synthetic lethality to eliminate T-ALL1R21CA189378-01A1SKORSKI, TOMASZTEMPLE UNIV OF THE COMMONWEALTH, PA$203,580DT
2015Detection of lethal prostate cancer with macromolecule-based, EGFL-7 targeted MR imaging approach1R21EB020946-01STEINMETZ, NICOLE FRANZISKACASE WESTERN RESERVE UNIVERSITY, OH$202,880EBIT
2015Nanoparticles based on histone deacetylase inhibitors for combination treatments1R21EB019175-01A1OUPICKY, DAVIDUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$202,504NANO
2015Genome-wide Analysis of Heparan Sulfate using CRISPR/Cas91R21CA199292-01ESKO, JEFFREY DUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$202,275ICI
2015Bioengineering a Living Tissue Conductor1R21HL126193-01A1BURSAC, NENADDUKE UNIVERSITY, NC$198,750ESTA
2015Cardiac radiofrequency ablation catheter with integrated OCT imaging1R21HL129147-01ROLLINS, ANDREW MARTINCASE WESTERN RESERVE UNIVERSITY, OH$198,125BMIT
2015Assessing Mitochondrial Metabolism by Magnetization Transfer MR Fingerprinting1R21HL126215-01A1YU, XINCASE WESTERN RESERVE UNIVERSITY, OH$198,125BMIT
2015Transmural Electrophysiological Imaging to Guide Catheter Ablation of Arrhythmias1R21HL125998-01WANG, LINWEIROCHESTER INSTITUTE OF TECHNOLOGY, NY$196,508BMIT
2015Maximizing small RNA delivery with signaling pepitdes1R21EB021454-01NGUYEN, JULIANESTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$196,112NANO
2015Ultrasound Elasticity imaging for gauging severity of posterior tibial tendon disorder1R21AR065732-01A1WITTE, RUSSELL SUNIVERSITY OF ARIZONA, AZ$195,119ZRG1
2015Label-free interrogation of heterogeneities in HSC fate decision signatures1R21EB018481-01A1HARLEY, BRENDAN A.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$193,022ZRG1
2015A Frequency-multiplexed flow cytometer for high throughput screening and drug discovery1R21EB019645-01A1DI CARLO, DINOJALALI, BAHRAMUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$192,500ISD
2015Modeling of Intervertebral Disc Degeneration1R21AR066240-01A1GU, WEIYONGUNIVERSITY OF MIAMI CORAL GABLES, FL$191,394SBSR
2015Going Local: Probing Real-Time Chemical Exchange Between Biofilm and Dental Composites1R21DE025370-01KOLEY, DIPANKAROREGON STATE UNIVERSITY, OR$190,970ODCS
2015Drug Delivery to Thrombotic Cardiovascular Disease1R21HL121130-01A1STEINMETZ, NICOLE FRANZISKACASE WESTERN RESERVE UNIVERSITY, OH$188,180GDD
2015Direct activation of hematopoietic transcription factors1R21HL129063-01POON, GREGORY MAN KAIGEORGIA STATE UNIVERSITY, GA$188,125MSFB
2015Stretchable electronic-bladder interface for neuroprosthetic control1R21EB020811-01BRUNS, TIMOTHY M.UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$183,974ZRG1
2015Magnetically Templated Regeneration Scaffolds for Nerve Injury Repair1R21NS093239-01RINALDI-RAMOS, CARLOS MSCHMIDT, CHRISTINE EUNIVERSITY OF FLORIDA, FL$181,880BTSS
2015Kernel-based Nonlinear Learning for Fast Magnetic Resonance Imaging with Sub-Nyquist Sampling1R21EB020861-01YING, LESLIE LEISTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$180,330BMIT
2015Real-time monitoring of blood viscoelasticity index during cardiopulmonary bypass1R21HL124486-01A1DECAMPLI, WILLIAM MICHAELDOGARIU, ARISTIDE CUNIVERSITY OF CENTRAL FLORIDA, FL$180,297BTSS
2015Gold nanoparticles as vascular disruptig agents in radiation therapy of NSCLC1R21CA188833-01A1BERBECO, ROSS I.DANA-FARBER CANCER INST, MA$180,171RTB
2015In Vivo Monitoring of Strain and Oxygen in TE Constructs Using MEMS-Based Sensors1R21AR066322-01A1GULDBERG, ROBERT EGEORGIA INSTITUTE OF TECHNOLOGY, GA$179,544MTE
2015A Flexible Epidermal Multimodal Health Monitor1R21EB019698-01MERCIER, PATRICK PUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$175,811ZRG1
2015New classes of optical switch chelate to study the role of Ca2+-oscillations in cell signaling1R21CA199512-01MARRIOTT, GERARDUNIVERSITY OF CALIFORNIA BERKELEY, CA$170,693ZRG1
2015Selective tumor inhibition by tumor-homing angiogenesis-suppressing nanofibers1R21CA200504-01MAO, CHUANBINUNIVERSITY OF OKLAHOMA, OK$164,432NANO
2014Therapy for leptomeningeal medulloblastoma by a novel implantable pump1R21NS088965-01ERDREICH-EPSTEIN, ANATCHILDREN'S HOSPITAL OF LOS ANGELES, CA$269,689GDD
20143D Subharmonic Pressure Maps of Vulnerable Plaques1R21HL119951-01A1FORSBERG, FLEMMINGTHOMAS JEFFERSON UNIVERSITY, PA$259,244MEDI
2014Bioinformatic analysis of molecular networks in peripheral artery disease1R21HL122721-01POPEL, ALEKSANDER S.JOHNS HOPKINS UNIVERSITY, MD$256,700ZRG1
2014Rational Design of Brighter, Monomeric Far-Red Fluorescent Proteins1R21EB018579-01MAYO, STEPHEN L.CALIFORNIA INSTITUTE OF TECHNOLOGY, CA$249,750ZRG1
2014Tunneling microfiber electrode arrays for stable neural recording1R21NS087531-01GARDNER, TIMOTHY JAMESBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$245,550BNVT
2014Investigating Abeta and alpha-synuclein toxicity by analyzing single-cell dynamic1R21NS087557-01LINDQUIST, SUSAN L.WHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$243,750CMND
2014MRI Assessment of Glucose Metabolism in Brain Tumor Using GlucoCEST1R21EB018934-01A1CHAN, WAI YANHUGO W. MOSER RES INST KENNEDY KRIEGER, MD$242,400BMIT
2014Exogenous Fluid Forces and Branching of the Mammalian Lung1R21HL118532-01A1NELSON, CELESTE MPRINCETON UNIVERSITY, NJ$242,375DEV1
2014Methamphetamine-induced alterations in brain tissue oxygenation1R21DA036721-01LIU, KE JIANUNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM$241,189NOIT
2014Ultra-deep tissue imaging by super-nonlinear fluorescence microscopy1R21EB019053-01MIN, WEICOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$240,000MEDI
2014Multiplexed chemical sensing on ultra-narrow electrophysiological neural probes1R21NS087453-01ROUKES, MICHAEL LCALIFORNIA INSTITUTE OF TECHNOLOGY, CA$239,511NANO
2014Probes for optogenetic interrogation and precise localization of neural circuits1R21NS084301-01A1WOLFE, JOHN CHARLESUNIVERSITY OF HOUSTON, TX$239,325BNVT
2014Low-Energy Shockwave Treatment Distal To Peripheral Vascular Disease1R21HL121561-01LERMAN, LILACH OMAYO CLINIC ROCHESTER, MN$238,500CICS
2014Targeted intraspinal stimulation for restoration of limb movement following spina1R21NS087320-01LUJAN, LUISMAYO CLINIC ROCHESTER, MN$238,500BNVT
2014MRI Contrast Agents for In vivo Monitoring of Stem Cell Differentiation1R21EB017881-01A1SHAPIRO, ERIKMICHIGAN STATE UNIVERSITY, MI$237,022CMIP
2014Safety Assessment of Pluripotent Stem Cell Therapy Using Nanotechnology1R21HL123928-01XU, CHUNHUIEMORY UNIVERSITY, GA$234,000BTSS
2014Engineered Intestinal Microenvironments as Preclinical Drug Screening Platforms1R21EB018407-01HEILSHORN, SARAH CSTANFORD UNIVERSITY, CA$233,599BMBI
2014KS-Detect: A sample-in, answer-out solution to the Diagnosis of Kaposi's Sarcoma1R21EB016803-01A1ERICKSON, DAVID CARLCORNELL UNIVERSITY, NY$232,817ISD
2014SNr DBS for the treatment of gait and postural disturbances in Parkinsons disease1R21NS085539-01A1MCCONNELL, GEORGE CDUKE UNIVERSITY, NC$232,650BNVT
2014MR Imaging of Upper Airway Dynamics in Obstructive Sleep Apnea1R21HL121794-01A1DARQUENNE, CHANTALUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$232,500RIBT
2014Integrated wide-field imaging and confocal microscopy with agile 3D beam scanning1R21EB018507-01DICKENSHEETS, DAVID LEERAJADHYAKSHA, MILINDMONTANA STATE UNIVERSITY - BOZEMAN, MT$231,770BMIT
2014Structural Biology of Tissue Factor-Induced Coagulation: Therapeutic Implications1R21HL122878-01BAJAJ, S PAULUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$231,000HT
2014Bioengineering Tracheas Through Targeting Activated CD471R21EB017184-01A1BADYLAK, STEPHEN F.ISENBERG, JEFFREY SUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$230,438BTSS
2014High-throughput sequencing of the T cell receptor in colorectal tumor infilt1R21CA173570-01A1ROBINS, HARLAN S.FRED HUTCHINSON CANCER RESEARCH CENTER, WA$229,680CONC
2014Developing Contrast-Enhanced Ultrasound of Thrombosis via SPIO-RL Platelets1R21HL119928-01A1OLDENBURG, AMY LUNIV OF NORTH CAROLINA CHAPEL HILL, NC$225,831BMIT
2014Impact of the micromechanical environment on inflammation in AAA progression1R21HL121493-01A1CHESLER, NAOMI CLIU, BOUNIVERSITY OF WISCONSIN-MADISON, WI$225,750ZRG1
2014Identifying high risk mammographic features in women with benign breast dise1R21CA186734-01VACHON, CELINE MMAYO CLINIC ROCHESTER, MN$225,661EPIC
2014Prediction of Motor Outcome after Acute Stroke using Diffusional Kurtosis Imaging1R21NS085475-01A1ADKINS, DEANNA LJENSEN, JENS HMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$224,250MEDI
2014In Host Remodeling of Grafts to Functional Arteries-Translation to Mature Animals1R21HL124479-01ROBERTSON, ANNE MARIEWANG, YADONGUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$223,440AICS
2014Cardio-Pulmonary Stethoscope: A novel radio frequency sensor for non-invasive mea1R21HL124457-01ISKANDER, MAGDYSETO, TODD BUNIVERSITY OF HAWAII AT MANOA, HI$221,976ZRG1
2014Protein interaction study In-vitro and in live cells with optofluidic lasers1R21EB016783-01A1FAN, XUDONGUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$221,333ISD
2014Deconstructing the cues in the mesenchymal stem cell microenvironment that promot1R21HL121757-01KILIAN, KRISTOPHER ALANUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$220,241VCMB
2014Matrilysin-Sensing Gene Delivery Vectors for Colorectal Cancer Therapy1R21CA187316-01SUH, JUNGHAERICE UNIVERSITY, TX$214,335GDD
2014Small Quantum Dots for Super-Resolution of Neuronal Sub-Synaptic Structures1R21NS087413-01SELVIN, PAUL RUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$213,303EBIT
2014Picosecond pulse technology for non-invasive electrostimulation1R21EB016912-01A1PAKHOMOV, ANDREI GXIAO, SHUOLD DOMINION UNIVERSITY, VA$210,805BNVT
2014Massively parallel interferometric confocal microscopy using degenerate lasers1R21HL125125-01A1CAO, HUICHOMA, MICHAEL ANDREWYALE UNIVERSITY, CT$209,850EBIT
2014Bacteriophytochrome-based optogenetic tools for mammalian gene regulation1R21EB018539-01GOMELSKY, MARKUNIVERSITY OF WYOMING, WY$209,760MIST
2014Engineering of multi-functional nucleolin-targeted nucleic acid delivery system.1R21EB017980-01ZHANG, SURONGUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$208,333CMIP
2014Engineering a multispecific receptor antagonist to inhibit cancer metastasis1R21CA187222-01COCHRAN, JENNIFER RSTANFORD UNIVERSITY, CA$208,258DMP
2014Molecular Imaging of FXIII in a Mouse model Coronary Microvascular Disease1R21HL119975-01A1ZHUANG, ZHENWUYALE UNIVERSITY, CT$208,125MEDI
2014Mechano-targeting of nanoparticles to atherogenic endothelium1R21HL122902-01BUTLER, PETER JPENNSYLVANIA STATE UNIVERSITY, THE, PA$204,569NANO
2014Improving Mobility for Bilateral Amputees with Coordinated Robotic Prostheses1R21HD076124-01A1GOLDFARB, MICHAELVANDERBILT UNIVERSITY, TN$204,159MRS
2014Improving f(c)MRI Accuracy by Accounting for the Implications of Data Processing1R21NS087450-01A1ROWE, DANIEL BMARQUETTE UNIVERSITY, WI$203,856BMRD
2014Extracellular Proteolysis as a Molecular Stratification Tool for Cancer1R21CA186077-01CRAIK, CHARLES SCOTTUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$201,953MSFD
20144D cone beam CT reconstruction for radiotherapy via motion vector optimization1R21EB017978-01A1JIA, XUNUT SOUTHWESTERN MEDICAL CENTER, TX$201,875RTB
2014Mechanism and Control of the "Predatory," Levy Walks of Metastatic Cancer Cells1R21CA173232-01A1GRZYBOWSKI, BARTOSZ ANDRZEJNORTHWESTERN UNIVERSITY, IL$198,592TPM
2014Fluorescence lifetime technique for detection of radiation necrosis vs gliom1R21CA178578-01A1MARCU, LAURAUNIVERSITY OF CALIFORNIA AT DAVIS, CA$196,906ZRG1
2014High-resolution in vivo and non-invasive imaging of myocardial fibers1R21HL122759-01LIU, CHUNLEIDUKE UNIVERSITY, NC$196,250BMIT
2014Biomechanics of Human Articular Cartilage Measured In Vivo1R21AR066230-01NEU, COREY PPURDUE UNIVERSITY, IN$195,331SBSR
2014Synthetic hemostats for trauma treatment1R21EB018637-01A1PUN, SUZIE H.WHITE, NATHAN JUNIVERSITY OF WASHINGTON, WA$193,125BMBI
2014Computational and In Vivo Analysis of Applied Apical Torsion for Cardiac Support1R21EB017807-01A1TRUMBLE, DENNIS ROBERTCARNEGIE-MELLON UNIVERSITY, PA$189,483BTSS
2014Analysis of the cellular secretome by targeted subcellular proteomics1R21CA188945-01MUDDIMAN, DAVID C.RAO, BALAJI MNORTH CAROLINA STATE UNIVERSITY RALEIGH, NC$186,981EBIT
2014Biodegradable Polymerized Simvastatin1R21EB017902-01PULEO, DAVID A.UNIVERSITY OF KENTUCKY, KY$186,334BMBI
2014Quantitative Motility Phenotyping of Basal Breast Cancer in a 3D Microenvironment1R21CA179204-01A1OLDENBURG, AMY LUNIV OF NORTH CAROLINA CHAPEL HILL, NC$185,155EBIT
2014Targeted Microbubbles for Noninvasive Measurement of Tumor VEGF Levels1R21EB018034-01A1BORDEN, MARK ANDREWGOODWIN, ANDREW PUNIVERSITY OF COLORADO, CO$184,130ZRG1
2014Novel Cell Delivery Method for Brain Tumor Therapy1R21CA189223-01A1BADIE, BEHNAMBECKMAN RESEARCH INSTITUTE/CITY OF HOPE, CA$183,969BTSS
2014Molecular Imaging to Identify Tumor Margins1R21CA183160-01BASILION, JAMES PETERCASE WESTERN RESERVE UNIVERSITY, OH$172,369CMIP
2014Neurosurgical Intracerebral Hemorrhage Evacuation (NICHE) Robot1R21EB018581-01DESAI, JAYDEV P.UNIV OF MARYLAND, COLLEGE PARK, MD$171,930BNVT
2014Non-collagenous proteins vs. bone fragility1R21AR066925-01WANG, XIAODUUNIVERSITY OF TEXAS SAN ANTONIO, TX$166,191SBSR
2014Targeting TF/CD44v6 for In Vivo Nano-generated alpha-therapy of Ovarian Cancer1R21CA182748-01A1DEUTSCHER, SUSAN LUNIVERSITY OF MISSOURI-COLUMBIA, MO$166,031CMIP
2014Imaging IDH1 Mutations in Glioma and Other Malignancies1R21CA182025-01CHITNENI, SATISH K.DUKE UNIVERSITY, NC$136,590CMIP
2014Utility of Effusion Cytology and Image Analysis in the Diagnosis of Mesothelioma1R21CA188938-01ROHDE, GUSTAVO KUNDECARNEGIE-MELLON UNIVERSITY, PA$93,800BDMA

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