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NIH funding notice PA-16-040

Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21)

Closed on June 28, 2018.

Posted
November 20, 2015
Close date
June 28, 2018
Activity codes
R21
Institutes taking part
NCI, NICHD, NIDA, NINDS, NIAMS

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-12-284 Exploratory/Developmental Bioengineering Research Grants (EBRG) [R21]
  2. 2 steps back: PA-10-010 Exploratory/Developmental Bioengineering Research Grants (EBRG) [R21]
  3. 3 steps back: PA-06-418 Exploratory/Developmental Bioengineering Research Grants(EBRG) [R21]
  4. 4 steps back: PA-03-058

Replaced by PA-18-286.

Who won it before

278 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $59,055,122 in first-year total cost, median $210,865.

Most frequent study sections

  1. Bioengineering, Technology and Surgical Sciences Study Section[BTSS]25
  2. Biomedical Imaging Technology A Study Section[BMIT-A]24
  3. Nanotechnology Study Section[NANO]16
  4. Biomedical Imaging Technology B Study Section[BMIT-B]15
  5. Biomaterials and Biointerfaces Study Section[BMBI]14

Most frequent institutions

  1. UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN14
  2. STANFORD UNIVERSITY8
  3. UNIVERSITY OF PITTSBURGH AT PITTSBURGH8
  4. CASE WESTERN RESERVE UNIVERSITY7
  5. UNIVERSITY OF WISCONSIN-MADISON7
Competing awards under PA-16-040 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
20193D Imaging of Tumor Mechanobiology Using Nanobomb Optical Coherence Elastography1R21CA231561-01A1SOKOLOV, KONSTANTIN VUNIVERSITY OF TX MD ANDERSON CAN CTR, TX$184,005NANO
2018Bioengineering of vein grafts to resist intimal hyperplasia1R21EB024308-01A1FERRAN, CHRISTIANEBETH ISRAEL DEACONESS MEDICAL CENTER, MA$262,500BTSS
2018High-performance Positron Emission Tomography for brain imaging1R21EB023391-01A1SABET, HAMIDMASSACHUSETTS GENERAL HOSPITAL, MA$252,750BMIT
2018Immune-Cancer Cell Interactions in a 3D Bioprinted Tumor Microenvironment1R21CA224422-01A1UNUTMAZ, DERYAJACKSON LABORATORY, ME$243,860BMBI
2018Physeal cartilage tissue engineering using mesenchymal stem cells directed towards chondrogenesis1R21HD092109-01A1BRYANT, STEPHANIE JPAYNE, KARIN AUNIVERSITY OF COLORADO DENVER, CO$238,144SBSR
2018Measuring CSF shunt flow with MRI using flow enhancement of signal intensity (Shunt-FENSI)1R21HD095314-01SUTTON, BRADLEY PUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$237,463MEDI
2018Physical detection of HLA-C binding peptides to identify and predict immunogenic personal neoepitopes for improving cancer vaccines1R21CA216772-01A1KESKIN, DERIN BDANA-FARBER CANCER INST, MA$232,224CII
20183D Bioprinting for Esophageal Reconstruction1R21EB022830-01A1PANOSKALTSIS-MORTARI, ANGELAUNIVERSITY OF MINNESOTA, MN$230,250BTSS
2018Intraoperative Measurement of Ligament Tension to Guide Knee Arthroplasty1R21EB024957-01A1THELEN, DARRYL GUNIVERSITY OF WISCONSIN-MADISON, WI$223,140BTSS
2018Reducing recall rates of screening mammography with deep convolutional neural network1R21CA225175-01A1KIM, SUNGHEON GENEMOY, LINDANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$218,865BMIT
2018Blocking ligand-dependent BMP signaling as an anti-melanoma strategy1R21CA228120-01CEOL, CRAIG JOSEPHUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$218,588CII
2018Rapid High-Resolution 1H-MRSI for Metabolic Imaging of the Brain1R21EB023413-01A1LIANG, ZHI-PEIUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$217,844BMIT
20183D biomimetic image-based stromal models of pancreatic cancer for drug screening1R21CA224280-01A1CAMPAGNOLA, PAUL JSKALA, MELISSA CAROLINEUNIVERSITY OF WISCONSIN-MADISON, WI$213,829CMT
2018Extracellular matrix regulation of lung adenocarcinoma signaling and drug responsiveness1R21CA216066-01A1UNDERHILL, GREGORY HUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$211,797TME
2018Elucidating skeletal stem cell function using engineered 3D multicellular structures1R21AR072778-01HSIAO, EDWARD CUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$210,925SBSR
2018Taste Receptor Family 2 Member 9 as a novel target for imaging Cancer Associated Fibroblasts in pancreatic cancer1R21CA231196-01KELLY, KIMBERLY A.UNIVERSITY OF VIRGINIA, VA$210,703CMIP
2018High Sensitivity Detection of Mutant cf-ctDNA with DNA-Guided Argonaut Enzymes1R21CA227056-01BAU, HAIM HUNIVERSITY OF PENNSYLVANIA, PA$210,105GCAT
2018Immunoswitch: A novel nanoparticle-based approach to immunotherapy1R21EB023411-01A1SCHNECK, JONATHAN PJOHNS HOPKINS UNIVERSITY, MD$204,688TTT
2018Targeting tissue factor as a novel oncotarget for immunotherapy of triple negative breast cancer1R21CA216697-01A1HU, ZHIWEIOHIO STATE UNIVERSITY, OH$203,580CII
2018Ultrasound elestography for non-invasive assessment of tendon healing1R21AR073961-01LOISELLE, ALAYNARICHARDS, MICHAEL SCOTTUNIVERSITY OF ROCHESTER, NY$203,280SBSR
2018Development of intensity modulated radiation therapy for small animal research1R21CA228160-01SHENG, KEUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$202,819RTB
2018RADIOMICS-BASED PROGNOSTIC MODEL OF CERVICAL CANCER HABITATS1R21CA223799-01GRIGSBY, PERRY WAYNELI, HUAWASHINGTON UNIVERSITY, MO$202,601RTB
2018Microfluidic Photoreactor for Treatment of Hyperbilirubinemia1R21HD096301-01BAIO, JOE EHIGGINS, ADAM ZSCHILKE, KATE FOREGON STATE UNIVERSITY, OR$201,837ISD
2018Antibody-Molecular Container Conjugates for Targeted Delivery1R21CA226830-01BRIKEN, VOLKERISAACS, LYLE DUNIV OF MARYLAND, COLLEGE PARK, MD$198,276SBCA
2018Nanotechnology for Non-perturbative, Longitudinal Sampling from hiPSC Cardiomyocytes1R21EB025332-01MELOSH, NICHOLAS ASTANFORD UNIVERSITY, CA$196,250ISD
20183D Printing of Anatomically Realistic Phantoms for Optimization of Imaging Algorithms1R21EB025549-01A1LO, JOSEPH YWILEY, BENJAMIN J.DUKE UNIVERSITY, NC$189,424BMIT
2018Self-administration of Near-Infrared Fluorescent Molecular Imaging Probes for Non-Invasive Early Detection and Treatment Monitoring of Rheumatoid Arthritis1R21AR072314-01A1THURBER, GREGUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$187,785ACTS
2018Amniotic Membrane Derived Matrix for Large Bone Defect Repair1R21DE026582-01A1HARLEY, BRENDAN A.WHEELER, MATTHEW BUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$187,318ODCS
2018Interrogating tension-adhesion coupling via high-speed deformation-relaxation1R21CA220202-01A1LIN, HAORUTGERS, THE STATE UNIV OF N.J., NJ$184,659MABS
2018Mutagenesis and migration in glioblastoma cells1R21CA220111-01A1AHN, EUN HYUNUNIVERSITY OF WASHINGTON, WA$179,240RTB
2018Highly Accelerated Chemical Exchange Saturation Transfer MRI Using Compressed Sensing1R21CA227783-01A1HEO, HYE YOUNGJOHNS HOPKINS UNIVERSITY, MD$178,056BMIT
2018Enabling NIR-PIT therapy to treat deep-tissue cancer1R21CA223969-01A1SADDOW, STEPHEN EDWARDUNIVERSITY OF SOUTH FLORIDA, FL$177,876MEDI
2018Microfluidic Engineering of Artificial-Antigen Presenting Cells for the Biomanufacturing of Tumor-Specific T-Cells1R21EB026900-01LEE, ABRAHAM PUNIVERSITY OF CALIFORNIA-IRVINE, CA$176,380ZRG1
2018In situ Investigation of dynamic protein-protein interactions in live cells via Magnetic Co-concentration (MCoC)1R21CA224364-01JUN, YOUNG-WOOKUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$173,728ISD
2018Targeting the CAR Membrane Microenvironment to Enhance the Sensitivity of Receptor Triggering1R21CA226962-01VEATCH, SARAH LUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$169,378BBM
2018Synthetic nucleocapsids: a new peptide library platform1R21CA232430-01KING, NEILPUN, SUZIE H.UNIVERSITY OF WASHINGTON, WA$169,106NANO
2018Single cell functional dissection of tumor microenviornment-driven drug resistance1R21CA220082-01A1WOOD, KRIS C.DUKE UNIVERSITY, NC$164,963BMCT
2018A Synthetic Bone Marrow to Understand Breast Cancer Dormancy1R21CA223783-01A1PEYTON, SHELLY R.UNIVERSITY OF MASSACHUSETTS AMHERST, MA$161,059ICI
2017Characterization of Thyroid Nodules by Quantitative Ultrasound1R21CA212744-01LEE, STEPHANIE L.BOSTON MEDICAL CENTER, MA$274,504BMIT
2017Syndecan-1 in Mechanosensing of Engineered Microenvironments1R21EB023551-01A1BAKER, AARON BLAIRUNIVERSITY OF TEXAS AT AUSTIN, TX$251,650BMBI
2017Development of Hybrid Tracheas for Long-Segment Tracheal Reconstruction1R21EB025378-01LIN, CHIA-YING JAMESUNIVERSITY OF CINCINNATI, OH$244,703BMBI
2017A Low-Cost Tethered Capsule Endoscope for Esophageal Cancer Screening1R21EB023431-01RICHARDS-KORTUM, REBECCA R.RICE UNIVERSITY, TX$243,585BMIT
2017High-Frequency Resting State Connectivity fMRI1R21EB022803-01A1POSSE, STEFANUNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM$241,331ZRG1
2017Morphogenetic Self-Assembly of Human Heart Organoids1R21EB023573-01A1COSTA, KEVIN DSACHS, DAVIDICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$240,350BMBI
2017Fast Methods for Mapping Focused Ultrasound Pressure Fields1R21EB024199-01A1GRISSOM, WILLIAM AVANDERBILT UNIVERSITY, TN$235,694BMIT
2017Glycocalyx Mimetic Polysaccharides as Therapeutics for Atherosclerosis1R21EB024147-01A1BAKER, AARON BLAIRUNIVERSITY OF TEXAS AT AUSTIN, TX$234,750AICS
2017A High Throughput, Human, In Vitro Model of Neuronal Stretch Injury1R21NS098129-01A1FINAN, JOHN DENDEAVOR HEALTH CLINICAL OPERATIONS, IL$234,000ZRG1
2017Plasma clearance of water soluble and albumin bound toxins using graphene oxide nanoengineered laminates1R21EB023527-01A1GABORSKI, THOMAS RMOGHADDAM, SAEEDUNIVERSITY OF FLORIDA, FL$232,294NANO
2017Radiolabeled FASN Inhibitors for PET Imaging1R21CA213157-01BABICH, JOHN WWEILL MEDICAL COLL OF CORNELL UNIV, NY$229,013CMIP
2017Establishing Mechanisms of Human Proximal Tubule Regeneration in an Engineered Organ on Chip Platform1R21EB025534-01MCCAIN, MEGAN LAURAMCMAHON, ANDREW P.UNIVERSITY OF SOUTHERN CALIFORNIA, CA$228,380PBKD
2017Imaging the efficacy of TRAIL-enhanced cancer immunotherapy1R21CA213139-01A1ADUSUMILLI, PRASAD S.PONOMAREV, VLADIMIRSLOAN-KETTERING INST CAN RESEARCH, NY$225,504MEDI
2017Robotic platform for high-density in vivo intracellular recording from mammalian circuits1R21NS103098-01HARNETT, MARK THOMASKODANDARAMAIAH, SUHASA BUNIVERSITY OF MINNESOTA, MN$223,890BNVT
2017High speed ultrasonic communications for implanted medical devices1R21EB025327-01OELZE, MICHAEL L.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$220,858BMIT
2017Novel Reconstruction Paradigm for Multiphasic CT Imaging of Kidney Cancer1R21CA211035-01A1NOO, FREDERICXU, JINGYANUNIVERSITY OF UTAH, UT$215,483BMIT
2017Multifunctional fibers for high-throughput microfluidics1R21EB022729-01A1FINK, YOELVOLDMAN, JOELMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$206,954ISD
2017Dissecting protein activities by reversible photo-inactivation1R21CA224194-01WITTMANN, TORSTENUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$206,843ZRG1
2017A new class of CSF-1R radioligands for monitoring glioblastoma progression and therapy1R21CA205564-01A1CHIN, FREDERICK TSTANFORD UNIVERSITY, CA$205,187CMIP
2017Epigenetic modulation of SEC24D and circulating miR-605 in renal cell carcinoma1R21CA213977-01A1PILI, ROBERTOINDIANA UNIVERSITY INDIANAPOLIS, IN$203,580CONC
2017Detecting Mammographically-Occult Cancer in Women with Dense Breasts1R21CA216495-01NISHIKAWA, ROBERT MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$202,275BMIT
2017Mechano-Sensing CAR-T Cells for Solid Tumor Metastases1R21CA219225-01ZHAO, WEIANUNIVERSITY OF CALIFORNIA-IRVINE, CA$201,585BMBI
2017Using Second Harmonic Generation to Predict Metastatic Outcome in Colon Adenocarcinoma1R21CA208921-01A1BROWN, EDWARD BERNARDUNIVERSITY OF ROCHESTER, NY$200,807BMIT
2017Endothelial DNA Methylation, Arteriogenic Capacity, and Shear Stress "Set-Point."1R21EB024323-01A1PRICE, RICHARD J.UNIVERSITY OF VIRGINIA, VA$200,313VCMB
2017In Vivo Arthrokinematics of Total Ankle Replacement and Ankle Arthrodesis1R21AR069773-01A1ANDERSON, ANDREW EDWARDUNIVERSITY OF UTAH, UT$199,815MRS
2017Noninvasive Pressure Estimation in Breast Cancer using Ultrasound1R21CA212851-01HOYT, KENNETHUNIVERSITY OF TEXAS DALLAS, TX$199,665BMIT
2017Noninvasive Detection of Prostate Cancer with a Label-Free Imaging System1R21CA198389-01A1YE, JING YONGUNIVERSITY OF TEXAS SAN ANTONIO, TX$198,406ZRG1
2017Cancer Targeting through Drug Conjugates1R21CA198684-01A1CHENG, JIANJUNUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$197,838ZRG1
2017Evaluation of machine learning to mobilize detection and therapy of developmental delay in children1R21HD091500-01WALL, DENNIS PAULSTANFORD UNIVERSITY, CA$196,250CPDD
2017Application of Single Cell Technologies to Resolve SI-NET Cell of Origin and Cytome Signature1R21CA215900-01MAGNESS, SCOTT TUNIV OF NORTH CAROLINA CHAPEL HILL, NC$196,210BMBI
2017Kinetic modeling of multiplexed SERS nanoparticles for quantitative molecular phenotyping (QMP) of breast cancer1R21CA215561-01LIU, JONATHAN T.C.UNIVERSITY OF WASHINGTON, WA$195,523BMIT
2017Enabling Diffusion-Weighted MRI Near Metallic Implants1R21EB023415-01A1KOCH, KEVIN MMEDICAL COLLEGE OF WISCONSIN, WI$190,799BMIT
2017Osteoinductive Microgel-Based Scaffolds for hMSC Delivery1R21AR071625-01ALGE, DANIELTEXAS ENGINEERING EXPERIMENT STATION, TX$190,196MTE
2017DECONVOLUTION OF CLONAL HETEROGENEITY FROM BULK AND SINGLE-CELL VARIATION DATA1R21CA216452-01SCHWARTZ, RUSSELL SCARNEGIE-MELLON UNIVERSITY, PA$187,064MABS
2017Engineering Antibody Drug Conjugates To Target P53-Defective Triple Negative Breast Cancer1R21CA213535-01A1LU, XIONGBINWANG, JINBAYLOR COLLEGE OF MEDICINE, TX$185,933CII
2017Metabolic Sodium MRI to Assess Early Response of Breast Cancer to Neoadjuvant Chemotherapy1R21CA213169-01A1BROWN, RYANMADELIN, GUILLAUMENEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$184,331BMIT
2017Scatter imaging for stereotactic ablative radiation therapy of lung cancer1R21CA213407-01A1CHU, JAMES C.H.RUSH UNIVERSITY MEDICAL CENTER, IL$178,829BMIT
2017CEST MRI assessment of tumor vascular permeability using non-labeled dextrans1R21CA215860-01LIU, GUANSHUHUGO W. MOSER RES INST KENNEDY KRIEGER, MD$175,782GDD
2017Imaging CAncer Screening Patch (CASP) for early diagnostics of cervical cancers1R21CA209063-01A1TKACZYK, TOMASZ SRICE UNIVERSITY, TX$174,374BMIT
2017Reprogramming Tumor-Associated Macrophages in PDAC with MicroRNA Nano-Vectors1R21CA213114-01A1AMIJI, MANSOOR M.MACKENZIE, GERARDO GUILLERMONORTHEASTERN UNIVERSITY, MA$170,738DMP
2017Non-Destructive Spectroscopic Assessment of Bone Water at Microscopic Resolution1R21AR071704-01PLESHKO, NANCYTEMPLE UNIV OF THE COMMONWEALTH, PA$170,387MTE
2017Cancer Cell Mechanical Profiling Analysis1R21CA208196-01A1RAO, JIANYUUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$168,744CBSS
2017Nanoparticle-based synthetic transcription factor to induce stem cell myogenesis1R21AR071101-01A1LEE, KIBUMRUTGERS, THE STATE UNIV OF N.J., NJ$168,194MTE
2017Hyperpolarized 13C imaging of mitochondrial metabolism for improved characterization of prostate cancer1R21CA213020-01MAYER, DIRKSIDDIQUI, MOHUMMAD MINHAJUNIVERSITY OF MARYLAND BALTIMORE, MD$167,702CMIP
2017A Hydrogel Model for Interstitial Fluid Flow1R21AR069791-01A1BRYANT, STEPHANIE JFERGUSON, VIRGINIA LEAUNIVERSITY OF COLORADO, CO$155,878SBSR
2016Advanced Ventricular Assist Device with Pulse Augmentation and Automatic Regurgitant Flow Shutoff1R21HL133871-01 · under PA-12-284FUKAMACHI, KIYOTAKACLEVELAND CLINIC LERNER COM-CWRU, OH$315,578BTSS
2016Microdroplet Transporter Protein Assays1R21EB022206-01 · under PA-12-284FARIS, GREGORY WSRI INTERNATIONAL, CA$306,112ZRG1
2016Determining the Biomechanical and Biological Response of Stretched Skin1R21EB021590-01A1 · under PA-12-284GOSAIN, ARUN KLURIE CHILDREN'S HOSPITAL OF CHICAGO, IL$289,809ZRG1
2016Development of Small Molecule Inhibitors of IL-18 to Prevent Intimal Hyperplasia1R21HL133821-01 · under PA-12-284PRADHAN-NABZDYK, LEENASUN, LIJUNBETH ISRAEL DEACONESS MEDICAL CENTER, MA$259,500BTSS
2016Computerized Visualization and Prediction of Coronary Artery Ischemia1R21HL132277-01 · under PA-12-284KUCEYESKI, AMY FRANCESMIN, JAMES KWEILL MEDICAL COLL OF CORNELL UNIV, NY$254,250BMIT
2016MIF20-loaded nanoparticles for TBI treatment1R21NS095147-01 · under PA-12-284DE LANEROLLE, NIHAL CZHOU, JIANGBINGYALE UNIVERSITY, CT$250,750BNVT
2016"Optogenetic control of amyloid beta protective gene expression in the C. elegans gut microbiota"1R21NS099870-01TABOR, JEFFREY JAYRICE UNIVERSITY, TX$250,375EBIT
2016Advanced Image-Based Approach to Assess How Fibrillar Collagen Modulates Airway Reactivity1R21HL129468-01A1 · under PA-12-284PARAMESWARAN, HARIKRISHNANBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$246,450LCMI
2016Dissecting the origins of fetal hemoglobin modulation of sickle cell vaso-occlusion1R21HL130818-01 · under PA-12-284WOOD, DAVID KEVINUNIVERSITY OF MINNESOTA, MN$242,670ISD
2016Development of a novel cell-based immune therapy using Nanoparticles and natural IgM-producing phagocytic B cells1R21CA205415-01 · under PA-12-284ZHONG, XUEMEIBOSTON MEDICAL CENTER, MA$241,061CII
2016Rapid micro-patterned stretching platform to study cell behaviors during atherosclerosis1R21EB022748-01 · under PA-12-284HAYWARD, RYAN CHRISTOPHERPEYTON, SHELLY R.UNIVERSITY OF MASSACHUSETTS AMHERST, MA$239,250BMBI
2016Abeta-Targeted Fluorinated Liposomes for 19F MRI Detection of Abeta Pathologies in APP/PSEN1 Mice1R21EB020153-01A1 · under PA-12-284TANIFUM, ERICBAYLOR COLLEGE OF MEDICINE, TX$237,750CMIP
2016Validating engineered hiPSC-derived cardiomyocytes as model cells1R21HL130993-01 · under PA-12-284PRUITT, BETH LSTANFORD UNIVERSITY, CA$236,819BMBI
2016Synthetic substrates for the expansion and differentiation of hPSC-derived NPCs1R21EB020767-01A1 · under PA-12-284BRAFMAN, DAVID AARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$235,952BTSS
2016Simultaneous imaging of myocardial blood flow and glucose metabolism using dynamic 18F-FDG PET1R21HL131385-01 · under PA-12-284WANG, GUOBAOUNIVERSITY OF CALIFORNIA AT DAVIS, CA$234,875BMIT
2016Imaging nanophysical properties of actively transporting bronchial mucus1R21HL130901-01A1 · under PA-12-284OLDENBURG, AMY LUNIV OF NORTH CAROLINA CHAPEL HILL, NC$234,634BMIT
2016Producing Nitric Oxide by Pulsed Electrical Discharge in Air for Inhalation Therapy1R21HL130956-01A1 · under PA-12-284YU, BINGLANMASSACHUSETTS GENERAL HOSPITAL, MA$234,514BTSS
2016Computational design of Cas9-based molecular imaging reagents1R21EB021453-01A1 · under PA-12-284HUANG, BOKORTEMME, TANJAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$231,996ZRG1
2016High Resolution and Functional MRI Assessment of Intracranial Atherosclerotic Plaque1R21HL130969-01 · under PA-12-284ANSARI, SAMEER ANORTHWESTERN UNIVERSITY AT CHICAGO, IL$231,750ZRG1
2016An inducible protein knockout strategy based on an orthogonal, ligand-activated E3 ubiquitin ligase1R21EB020898-01A1 · under PA-12-284XU, WENQINGUNIVERSITY OF WASHINGTON, WA$231,500MSFA
2016Engineered CARs Targeting FVIII-specific T and B Cells1R21HL127495-01A1 · under PA-12-284SCOTT, DAVID WILLIAMHENRY M. JACKSON FDN FOR THE ADV MIL/MED, MD$231,385HT
2016Single Cell Analysis of Cellular Senescence using a Novel Carbon Nanotube-Based Probe1R21EB023595-01SCHRLAU, MICHAEL GEORGEROCHESTER INSTITUTE OF TECHNOLOGY, NY$231,043NANO
2016Lymphatic contribution to progressive peripheral vascular disease and ulceration1R21HL132598-01 · under PA-12-284RASMUSSEN, JOHN CHARLESSEVICK, EVA M.UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$231,000ZRG1
20164D MR Imaging of Flow and Hemodynamics in Aortic Stenosis1R21HL132263-01A1 · under PA-12-284AMINI, AMIR AUNIVERSITY OF LOUISVILLE, KY$231,000MEDI
2016Vascularized cell-based device for restoring physiological homeostasis1R21EB022185-01 · under PA-12-284BOYD, NOLAN LEEUNIVERSITY OF LOUISVILLE, KY$228,593BTSS
2016Central Nervous System Tissue Organogenesis via Precise Growth Factor Tethering1R21NS096571-01 · under PA-12-284LEIPZIG, NIC DUNIVERSITY OF AKRON, OH$228,000BTSS
2016Multimodal (PET/MR/NIR) imaging supported drug delivery in inflammatory diseases1R21EB023104-01 · under PA-12-284ANDERSON, CAROLYN J.JANJIC, JELENA MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$228,000ZRG1
2016Regulation of mammalian cell physiology by a novel synthetic circadian clock1R21NS099813-01LEE, CHOOGONFLORIDA STATE UNIVERSITY, FL$228,000NNRS
2016Altered Neutrophil Function in Ventricular Assist Devices1R21HL132286-01 · under PA-12-284SCHMIDTKE, DAVID WUNIVERSITY OF TEXAS DALLAS, TX$223,395BTSS
2016A Computational Model-Enhanced Approach for Tumor Localization During Lumpectomy1R21EB022380-01 · under PA-12-284MESZOELY, INGRID MMIGA, MICHAEL IANVANDERBILT UNIVERSITY, TN$221,820ZRG1
2016A Novel Optogenetic Tool for Precise Mitochondrial Control1R21HL127599-01A1 · under PA-12-284ZHOU, LUFANGUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$221,350MIM
2016Rapid discovery of new biologics and cell-surface targets to direct cell behavior1R21EB022258-01A1SARKAR, CASIMUNIVERSITY OF MINNESOTA, MN$219,427DMP
2016Endotypes of thrombocytopenia in the critically ill1R21HL133891-01 · under PA-12-284CLERMONT, GILLESPARKER, ROBERT S.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$217,444ZRG1
2016Bioprinted Vascularized Tissue Constructs1R21AR070408-01 · under PA-12-284BUTCHER, JONATHAN TALBOTCORNELL UNIVERSITY, NY$216,728MTE
2016An objective noninvasive single-cell method to identify HSC differentiation stage1R21HL132642-01A1 · under PA-12-284KRAFT, MARY LUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$216,465EBIT
2016Quantitative Cardiac MRI for Detection of Subclinical Cardiotoxicity in Breast Cancer1R21HL129224-01A1 · under PA-12-284NEZAFAT, REZABETH ISRAEL DEACONESS MEDICAL CENTER, MA$216,250MEDI
2016Monitoring contractile forces during airway constriction1R21HL123522-01A1 · under PA-12-284KRISHNAN, RAMASWAMYBETH ISRAEL DEACONESS MEDICAL CENTER, MA$216,250RIBT
2016Oxygen-rich perfusate that is compatible with optical assessments of myocardial physiology1R21HL132618-01A1 · under PA-12-284KAY, MATTHEW W.GEORGE WASHINGTON UNIVERSITY, DC$215,343ZRG1
2016Protoacoustics - Clinical based range verification for Cancer Treatment1R21CA205063-01A1 · under PA-12-284AVERY, STEPHENUNIVERSITY OF PENNSYLVANIA, PA$214,807BMIT
2016Disambiguating coma etiologies by assessing the lability of EEG dynamics1R21NS096590-01A1 · under PA-12-284CHING, SHINUNGKUMMER, TERRANCE TWASHINGTON UNIVERSITY, MO$213,000NOIT
2016Quantitative imaging biomarkers of radiation-induced bone loss in radiotherapy patients1R21CA208821-01 · under PA-12-284MORRIS, CAROLZBIJEWSKI, WOJCIECH BARTOSZJOHNS HOPKINS UNIVERSITY, MD$211,410ZRG1
2016Biomechanical study on aortic-mitral coupling in transcatheter aortic valve replacement1R21HL127570-01A1 · under PA-12-284SUN, WEIGEORGIA INSTITUTE OF TECHNOLOGY, GA$210,763BTSS
2016Integrated drug-in-cell therapy of in-stent restenosis1R21HL131016-01A1 · under PA-12-284CHORNY, MICHAELCHILDREN'S HOSP OF PHILADELPHIA, PA$210,000NANO
2016Nanoscale Encapsulation for Fragment Based Drug Discovery1R21CA206958-01 · under PA-12-284WAND, A. JOSHUAUNIVERSITY OF PENNSYLVANIA, PA$209,670BBM
2016Matrix remodeling in microfluidic co-culture1R21HL132256-01 · under PA-12-284TSCHUMPERLIN, DANIEL J.MAYO CLINIC ROCHESTER, MN$209,160RIBT
2016Multifunctional Nanoparticles Containing sRAGE Potentiated Bioactive Peptides for Wound Healing1R21EB021570-01A1 · under PA-12-284BERTHIAUME, FRANCOISYARMUSH, MARTIN LRUTGERS, THE STATE UNIV OF N.J., NJ$208,351MTE
2016Noninvasive real-time intracardiac pressure measurements using subharmonic ultrasound1R21HL130899-01 · under PA-12-284DAVE, JAYDEVTHOMAS JEFFERSON UNIVERSITY, PA$205,790MEDI
2016Exosome analysis of drug-resistant cancer cells' response to nanoparticle therapy1R21CA190024-01A1 · under PA-12-284LIU, XUEWUMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$205,559NANO
2016Pulmonary Hypertension Associated with Sickle Cell Disease1R21HL129047-01A1 · under PA-12-284CHESLER, NAOMI CUNIVERSITY OF WISCONSIN-MADISON, WI$203,000BTSS
2016Near-infrared optogenetic control of the human heart1R21EB023106-01A1EFIMOV, IGOR RENTCHEVA, EMILIAGEORGE WASHINGTON UNIVERSITY, DC$199,375ZRG1
2016Effects of fluid shear stress on circulating tumor cells1R21CA196202-01A1 · under PA-12-284HENRY, MICHAEL DUNIVERSITY OF IOWA, IA$198,360TPM
2016Novel Ultrashort Echo Time Sequences for Brain MRI1R21NS089004-01A1 · under PA-12-284LARSON, PEDER ERIC ZUFALLUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$198,125NOIT
2016Magnetic Resonance Fingerprinting Assessments of Lung Disease1R21HL130839-01A1 · under PA-12-284DARRAH, REBECCA JFLASK, CHRISTOPHER ACASE WESTERN RESERVE UNIVERSITY, OH$198,125BMIT
2016Single-Cell Stethoscopes for Functional Cardiac Cell Assessment and Sorting1R21HL127655-01A1 · under PA-12-284MELOSH, NICHOLAS ASTANFORD UNIVERSITY, CA$197,500ISD
2016Intervertebral Disc Mechanics Measured by dualMRI In Vivo1R21AR066665-01A1 · under PA-12-284NEU, COREY PUNIVERSITY OF COLORADO, CO$195,659MTE
2016Volumetric Traction Force Tomography of Collective Cell Migration Dynamics1R21EB022927-01A1ADIE, STEVEN GRAHAMCORNELL UNIVERSITY, NY$195,256BMIT
2016Development of a Liposomal Nanostimulator to Improve Stem Cell-Based Revascularization Therapies1R21HL131469-01A1 · under PA-12-284KONG, HYUNJOONUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$194,473NANO
2016Ultrasound stimulation of the baroreflex1R21HL132257-01 · under PA-12-284YEN, JESSE T-PUNIVERSITY OF SOUTHERN CALIFORNIA, CA$193,900BTSS
2016RFID based Wireless System for Self-powered Implantable Pediatric Cardiac Sensors1R21HL127657-01A1 · under PA-12-284WEN, XUEJUNVIRGINIA COMMONWEALTH UNIVERSITY, VA$193,843BTSS
2016PGD: A shape memory degradable polymer for transcatheter atrial septal defect closure1R21HL126004-01A1 · under PA-12-284BOCKS, MARTINHOLLISTER, SCOTT JUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$193,750BTSS
2016Aortic Plaques and Stroke: Cardiovascular Therapy of Retrograde Embolization Risk1R21HL132357-01 · under PA-12-284MARKL, MICHAELNORTHWESTERN UNIVERSITY AT CHICAGO, IL$193,125HM
2016An Autologous, Culture-Free, Adipose Cell-Based Tissue Engineered Vascular Graft1R21HL130784-01 · under PA-12-284VORP, DAVID ALANUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$191,792BMBI
2016Oral Gene Delivery to Improve Iron Overload Disorders1R21EB023025-01 · under PA-12-284AMIJI, MANSOOR M.KIM, JONGHANNORTHEASTERN UNIVERSITY, MA$190,400GDD
2016Targeting Triple Negative Breast Cancer Using Nanoparticles Loaded with the Anti-Cancer Drug Aminoflavone1R21CA196653-01A1 · under PA-12-284GONG, SHAOQIN -XU, WEIUNIVERSITY OF WISCONSIN-MADISON, WI$182,144ZRG1
2016Developing a strategy to identify & validate pharmacodynamic kinase inhibitor biomarkers1R21CA199042-01A1 · under PA-12-284BIEBERICH, CHARLES J.UNIVERSITY OF MARYLAND BALTIMORE COUNTY, MD$178,103CBSS
2016Nanoparticle Remodeling of Pulmonary Junctions1R21HL129115-01A1 · under PA-12-284MURPHY, CATHERINE J.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$177,941LIRR
2016Imaging Tumor Associated Macrophages in Bone Sarcomas1R21CA190196-01A1 · under PA-12-284DALDRUP-LINK, HEIKE ELIZABETHSTANFORD UNIVERSITY, CA$171,839ZRG1
2016Macro-vasculature surrounding pulmonary nodules as a sign of malignancy1R21CA197493-01A1 · under PA-12-284PU, JIANTAOUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$167,475ZRG1
2016Exploiting Altered Porphyrin Synthesis for Metabolic Imaging of Glioblastoma1R21CA202694-01A1 · under PA-12-284KAO, JOSEPH PAO YUNGMAYER, DIRKUNIVERSITY OF MARYLAND BALTIMORE, MD$167,475CMIP
2016Impact of soluble and physical stimuli on tumor angiogenesis and drug sensitivity1R21CA202040-01 · under PA-12-284KREEGER, PAMELA KMASTERS, KRISTYN SUNIVERSITY OF WISCONSIN-MADISON, WI$166,388TME
2016Bioorthogonal labeling of extracellular matrix assembly1R21AR069248-01A1 · under PA-12-284CALVE, SARAHPURDUE UNIVERSITY, IN$160,387MTE
2015Portable Low Field Magnetic Resonance Device for Acute Lung Injury1R21HL124440-01A1 · under PA-12-284PATZ, SAMUELBRIGHAM AND WOMEN'S HOSPITAL, MA$274,394MEDI
2015Regional Measurement of Alveolar Partial Pressure of Oxygen with HPXe MRI.1R21HL125999-01A1 · under PA-12-284MURADYAN, IGABRIGHAM AND WOMEN'S HOSPITAL, MA$266,063ZRG1
2015High-Speed fMRI of Resting State Connectivity1R21EB018494-01A1 · under PA-12-284POSSE, STEFANUNIVERSITY OF NEW MEXICO HEALTH SCIS CTR, NM$263,786BMIT
2015MRI Characterization of Arrhythmogenic Scar in Ventricular Tachycardia1R21HL127650-01 · under PA-12-284ANTER, ELADNEZAFAT, REZABETH ISRAEL DEACONESS MEDICAL CENTER, MA$261,000ESTA
2015Engineered Tissue for Biomechanical Phenotyping of Cardiomyopathy Patients1R21HL126025-01 · under PA-12-284CAMPBELL, STUART GYALE UNIVERSITY, CT$249,750CCHF
2015Pulmonary arterial endothelial stiffness and shear-stress induced signaling1R21HL126040-01A1 · under PA-12-284SUKI, BELABOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$245,550RIBT
2015Computational Classification of Human Stem Cell-Derived Cardiomyocytes1R21HL122881-01A1 · under PA-12-284TUNG, LESLIEVIDAL, RENEJOHNS HOPKINS UNIVERSITY, MD$243,000BDMA
2015Lipid Nanoparticles for Targeted Delivery of Enhanced Costimulation Blockade1R21HL127355-01 · under PA-12-284RAIMONDI, GIORGIOJOHNS HOPKINS UNIVERSITY, MD$243,000NANO
2015MMP-targeted viral gene delivery vectors for treatment of infarcted heart1R21HL126053-01A1 · under PA-12-284SUH, JUNGHAERICE UNIVERSITY, TX$240,150GDD
2015NOVEL SYNTHETIC SDG TO TREAT TRAUMA-INDUCED INFLAMMATION1R21AT008291-01A1 · under PA-12-284CHRISTOFIDOU-SOLOMIDOU, MELPOWINKELSTEIN, BETH AUNIVERSITY OF PENNSYLVANIA, PA$240,000NOMD
2015An evaluation of a novel technology to assess neonatal jaundice1R21HD080768-01A1 · under PA-12-284TAYLOR, JAMES AUNIVERSITY OF WASHINGTON, WA$238,630PN
2015Fully optical high throughput screening platform for drug induced arrhythmias1R21HL123012-01A1 · under PA-12-284LAURITA, KENNETHCASE WESTERN RESERVE UNIVERSITY, OH$237,750BMIT
2015Xe129 MRI of the Lung: A New Technology to Assess Treatment for COPD1R21HL129112-01 · under PA-12-284QING, KUNUNIVERSITY OF VIRGINIA, VA$237,000ZRG1
2015Self-replicating RNA-nanoplexes for programming monocytes to regenerate the heart1R21HL126082-01A1 · under PA-12-284NGUYEN, JULIANESTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$236,008GDD
2015Optimizing Nanopore Protein Interactions1R21EB019232-01A1 · under PA-12-284ERVIN, ERICELECTRONIC BIOSCIENCES, INC., CA$234,992NANO
2015Machine learning with generative mixture models for fetal monitoring1R21HD080025-01A1 · under PA-12-284DJURIC, PETAR MQUIRK, J GERALDSTATE UNIVERSITY NEW YORK STONY BROOK, NY$234,571ZRG1
2015Cardiomyocyte-derived Venous Assist Device: Aiding peripheral blood flow1R21HL122882-01A1 · under PA-12-284SARVAZYAN, NARINEGEORGE WASHINGTON UNIVERSITY, DC$233,838BMBI
2015Nanoparticle Transport as a function of Physiologic and Hyperthermic Conditions in a 3D Vascularized Microfluidic Tumor Platform1R21EB019646-01 · under PA-12-284RYLANDER, MARISSA NICHOLEVLACHOS, PAVLOS PUNIVERSITY OF TEXAS AT AUSTIN, TX$233,531BMBI
2015Imaging regional transit time and pulmonary vascular resistance in the human lung1R21HL122753-01A1 · under PA-12-284HOPKINS, SUSAN RUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$232,500ZRG1
2015Photostable Multiplexing NanoAssays for Real-Time Study of Embryonic Stem Cells1R21HL127580-01 · under PA-12-284XU, X. NANCYOLD DOMINION UNIVERSITY, VA$232,500NANO
2015Systemic Inflammatory Response: The Effects of blood-air Interface after Cardiopulmonary Bypass1R21HL125961-01A1 · under PA-12-284HAFT, JONATHANUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$232,500BTSS
2015Are 3T MRI Exams Safe For Patients with Pacemakers and ICDs?1R21HL127433-01 · under PA-12-284ENNIS, DANIEL BUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$231,000MEDI
2015Detection and Grading of Fatty and Fibrotic Liver Using Quantitative Ultrasound1R21EB020766-01 · under PA-12-284OELZE, MICHAEL L.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$229,061MEDI
2015Oxygen Microbubble Peritoneal Ventilation Treatment for Acute Respiratory Distress Syndrome1R21HL129144-01 · under PA-12-284TERRY, BENJAMINUNIVERSITY OF NEBRASKA LINCOLN, NE$228,258SAT
2015Stimulated emission reduced fluorescence (SERF) for breaking and extending the fundamental imaging-depth of two photon microscopy1R21EB020073-01 · under PA-12-284MIN, WEICOLUMBIA UNIV NEW YORK MORNINGSIDE, NY$228,000BMIT
2015Ultra-high Resolution 3D MR Spectroscopic Imaging1R21EB021013-01 · under PA-12-284LIANG, ZHI-PEIUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$227,872BMIT
2015Turn the heat on: High resolution fluorescence imaging via temperature modulation1R21CA191389-01A1 · under PA-12-284GULSEN, GULTEKINUNIVERSITY OF CALIFORNIA-IRVINE, CA$227,276BMIT
2015Dynamic force control of cardiac ablation catheters1R21HL126081-01 · under PA-12-284PARK, YONG-LAECARNEGIE-MELLON UNIVERSITY, PA$226,813BTSS
2015Development of large diameter biodegradable stents for congenital heart disease1R21HL129095-01 · under PA-12-284NUGENT, ALAN WILLIAMUT SOUTHWESTERN MEDICAL CENTER, TX$226,147BTSS
2015Identification of AF Ablation Targets via a Steerable Actuated Catheter1R21EB019161-01A1 · under PA-12-284DESAI, JAYDEV P.UNIV OF MARYLAND, COLLEGE PARK, MD$222,800BMIT
2015Second Harmonic Generation analysis of the ECM in idiopathic pulmonary fibrosis1R21HL126190-01A1 · under PA-12-284CAMPAGNOLA, PAUL JSANDBO, NATHAN KSINGH, VIKASUNIVERSITY OF WISCONSIN-MADISON, WI$218,370EBIT
2015Dynamic MRI Image Analysis for Studying Thoracic Insufficiency Syndrome1R21HL124462-01A1 · under PA-12-284CAMPBELL, ROBERT MURRAYUDUPA, JAYARAM KUNIVERSITY OF PENNSYLVANIA, PA$217,708ZRG1
2015SPARSITY-DRIVEN IDEAL OBSERVERS FOR GUIDING IMAGING HARDWARE OPTIMIZATION1R21EB020168-01A1 · under PA-12-284ANASTASIO, MARK AWASHINGTON UNIVERSITY, MO$213,000BMIT
2015Biomolecule-Directed Assembly for Enhancing Near IR Energy Transfer Processes in Theranostics1R21EB020911-01 · under PA-12-284CHA, JENNIFER NGOODWIN, ANDREW PPARK, WOUNJHANGUNIVERSITY OF COLORADO, CO$211,076NANO
2015Projection Imaging of Peripheral Vascular Calcifications1R21HL126015-01A1 · under PA-12-284EDELMAN, ROBERT R.ENDEAVOR HEALTH CLINICAL OPERATIONS, IL$208,745ZRG1
2015Outside-In Regenerative Therapy for Abdominal Aortic Aneurysm1R21HL129066-01 · under PA-12-284CURCI, JOHN AVORP, DAVID ALANUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$206,747BTSS
2015Free-standing nanowire transistor bio-probes for intracellular and implanted recording1R21EB020822-01 · under PA-12-284QING, QUANARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$204,127BNVT
2015Personalized RAD52-dependent synthetic lethality to eliminate T-ALL1R21CA189378-01A1 · under PA-12-284SKORSKI, TOMASZTEMPLE UNIV OF THE COMMONWEALTH, PA$203,580DT
2015Detection of lethal prostate cancer with macromolecule-based, EGFL-7 targeted MR imaging approach1R21EB020946-01 · under PA-12-284STEINMETZ, NICOLE FRANZISKACASE WESTERN RESERVE UNIVERSITY, OH$202,880EBIT
2015Nanoparticles based on histone deacetylase inhibitors for combination treatments1R21EB019175-01A1 · under PA-12-284OUPICKY, DAVIDUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$202,504NANO
2015Genome-wide Analysis of Heparan Sulfate using CRISPR/Cas91R21CA199292-01 · under PA-12-284ESKO, JEFFREY DUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$202,275ICI
2015Bioengineering a Living Tissue Conductor1R21HL126193-01A1 · under PA-12-284BURSAC, NENADDUKE UNIVERSITY, NC$198,750ESTA
2015Cardiac radiofrequency ablation catheter with integrated OCT imaging1R21HL129147-01 · under PA-12-284ROLLINS, ANDREW MARTINCASE WESTERN RESERVE UNIVERSITY, OH$198,125BMIT
2015Assessing Mitochondrial Metabolism by Magnetization Transfer MR Fingerprinting1R21HL126215-01A1 · under PA-12-284YU, XINCASE WESTERN RESERVE UNIVERSITY, OH$198,125BMIT
2015Transmural Electrophysiological Imaging to Guide Catheter Ablation of Arrhythmias1R21HL125998-01 · under PA-12-284WANG, LINWEIROCHESTER INSTITUTE OF TECHNOLOGY, NY$196,508BMIT
2015Maximizing small RNA delivery with signaling pepitdes1R21EB021454-01 · under PA-12-284NGUYEN, JULIANESTATE UNIVERSITY OF NEW YORK AT BUFFALO, NY$196,112NANO

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