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NIH funding notice PA-14-042

NIH Pathway to Independence Award (Parent K99/R00)

Closed on January 8, 2015.

Posted
December 19, 2013
Close date
January 8, 2015
Activity codes
K99, R00
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NLM, NCCAM, ORIP, OBSSR, ODS, IC

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-11-197 NIH Pathway to Independence Award (Parent K99/R00)
  2. 2 steps back: PA-10-063 NIH Pathway to Independence Award (Parent K99/R00)
  3. 3 steps back: PA-09-036 NIH Pathway to Independence Award (K99/R00)
  4. 4 steps back: PA-07-297 NIH Pathway to Independence (PI) Award (K99/R00)
  5. 5 steps back: PA-06-133

Replaced by PA-15-083.

Who won it before

436 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $46,901,925 in first-year total cost, median $97,809.

Most frequent study sections

  1. Transition to Independence Study Section (I)[NCI-I]75
  2. NST-2 Study Section [NST-2]29
  3. Special Emphasis Panel[ZHL1 CSR-P (O1)]22
  4. Special Emphasis Panel[ZHL1 CSR-P (M1)]18
  5. Biological Aging Study Section[NIA-B]13

Most frequent institutions

  1. STANFORD UNIVERSITY40
  2. UNIVERSITY OF CALIFORNIA, SAN FRANCISCO19
  3. MASSACHUSETTS GENERAL HOSPITAL16
  4. COLUMBIA UNIVERSITY HEALTH SCIENCES12
  5. SCRIPPS RESEARCH INSTITUTE, THE11
Competing awards under PA-14-042 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2016Influence of chronic pain on mesolimbic dopamine activity and motivated behavior1K99DA040016-01TAYLOR, ANNAUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$158,544ZDA1
2015The role of PARP inhibitor target engagement in breast cancer1K99CA198857-01DUBACH, JOHNMASSACHUSETTS GENERAL HOSPITAL, MA$179,058NCI
2015Experience-dependent modulation of innate neural circuits1K99DC014516-01ROOT, CORY MATTHEWCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$175,554CDRC
2015Nucleus accumbens synaptic mechanisms of opiate reward and aversion1K99DA037279-01A1ROTHWELL, PATRICKSTANFORD UNIVERSITY, CA$174,820ZDA1
2015The Impact of Opioids on Chronic Pain: Clinical Research and Career Training in Spinal Cord fMRI and Brain Reward Systems1K99DA040154-01MARTUCCI, KATHERINE THERESASTANFORD UNIVERSITY, CA$174,820ZDA1
2015The Role of Hepatitis Delta Virus in Sjogrens Syndrome1K99DE021745-01 · under PA-10-063WELLER, MELODIE LYNNU.S. NAT'L INST/DENTAL/CRANIOFACIAL RES, MD$172,500DSR
2015A systematic dissection of oncogenic KRAS signaling for target identification and therapeutic development1K99CA194284-01YUAN, TINADANA-FARBER CANCER INST, MA$172,260NCI
2015Ultrasensitive Quantitation of Circulating Tumor DNA1K99CA187192-01A1NEWMAN, AARON MSTANFORD UNIVERSITY, CA$171,048NCI
2015Functional dissection of oncogenic enhancers1K99CA197869-01HERRANZ, DANIELCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$170,856NCI
2015ROLE OF VITAMIN B5 AND COENZYME A METABOLISM IN PI3K DRIVEN TUMORIGENESIS1K99CA194314-01DIBBLE, CHRISTIANBETH ISRAEL DEACONESS MEDICAL CENTER, MA$169,668NCI
2015Drivers and dependencies as therapeutic targets in KRAS-mutant lung cancers1K99CA197504-01MANCHADO-ROBLES, EUSEBIOSLOAN-KETTERING INST CAN RESEARCH, NY$157,891NCI
2015Measuring and manipulating reward circuit plasticity in opiate addiction models1K99DA038706-01HEARING, MATTHEW CARLUNIVERSITY OF MINNESOTA, MN$151,077ZDA1
2015Contributions of Nitrergic Interneurons and NO Signaling in Cocaine Relapse1K99DA040004-01SCOFIELD, MICHAEL DAVIDMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$148,419ZDA1
2015The SMYD3-ERK5 signaling module in pancreatic cancer1K99CA197816-01MAZUR, PAWEL K.STANFORD UNIVERSITY, CA$147,179NCI
2015Maternal Diabetes during Pregnancy and Neurodevelopment in the Offspring1K99HD080813-01A1VIRK, JASVEERUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$145,987CHHD
2015Alcohol-induced plasticity within CRF1 microcircuits in distinct amygdala nuclei1K99AA023002-01A1HERMAN, MELISSA ASCRIPPS RESEARCH INSTITUTE, THE, CA$141,750AA
2015DEFINING DYNORPHIN-CRF CIRCUITS IN STRESS AND NICOTINE BEHAVIORS1K99DA038725-01AL-HASANI, REAMWASHINGTON UNIVERSITY, MO$140,122ZDA1
2015Nitric oxide coupling and BH4 availability roles in muscle dysfunction with COPD1K99HL125756-01LAYEC, GWENAELUNIVERSITY OF UTAH, UT$138,780ZHL1
2015Networks underlying visual modulation of speech perception1K99DC013828-01A1BRANG, DAVIDNORTHWESTERN UNIVERSITY, IL$137,441CDRC
2015CD33 and Alzheimer's Disease: from Biology to Therapy1K99AG049056-01GRICIUC, ANAMASSACHUSETTS GENERAL HOSPITAL, MA$137,160NIA
2015Development of Zr-89 based ImmunoPET agents for Idiopathic Pulmonary Fibrosis1K99HL125728-01BOROS, ESZTERMASSACHUSETTS GENERAL HOSPITAL, MA$137,080ZHL1
2015Oral Corticosteroid Use During Pregnancy and Risk for Preterm Birth1K99HD082412-01A1PALMSTEN, KRISTINUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$137,079CHHD
2015Beside Monitor of Cerebral Metabolism in Premature Infants with Intraventricular Hemorrhage and Post-Hemorrhagic Hydrocephalus1K99HD083512-01LIN, PEI-YIMASSACHUSETTS GENERAL HOSPITAL, MA$137,000CHHD
2015To define the role of SOX9 and Sox9+ cells in alveolar homeostasis and regeneration1K99HL127181-01TATA, PURUSHOTHAMA RAOMASSACHUSETTS GENERAL HOSPITAL, MA$136,405MTI
2015Network Medicine Approaches to Cachexia in COPD1K99HL121087-01A1MCDONALD DONNELLY, MERRY-LYNN NOELLEBRIGHAM AND WOMEN'S HOSPITAL, MA$136,350ZHL1
2015Role of apolipoprotein E in age and amyloid beta related neuronal dysfunction1K99AG047336-01A1HUDRY, ELOISEMASSACHUSETTS GENERAL HOSPITAL, MA$136,306NIA
2015Danger Signaling and Spread of Injury after Myocardial Infarction1K99HL129168-01KING, KEVIN RMASSACHUSETTS GENERAL HOSPITAL, MA$136,150MTI
2015Using extracellular metabolites to understand and revert protumoral effects of Tumor-Associated Macrophages1K99CA191021-01A1CARMONA-FONTAINE, CARLOSSLOAN-KETTERING INST CAN RESEARCH, NY$135,835NCI
2015Targeting ethanol-induced gut dysbiosis with synbiotics to treat alcoholic liver1K99AA023266-01 · under PA-11-197CRESCI, GAIL ANNCLEVELAND CLINIC LERNER COM-CWRU, OH$135,648ZAA1
2015Insulin Resistance, Biomarkers of Brain Function, and Intermittent Calorie Restriction1K99AG047282-01A1WILLETTE, AURIELIOWA STATE UNIVERSITY, IA$134,730NIA
2015Understanding the risk of obesity in food-insecure children: the hidden role of stress1K99HD084758-01LEUNG, CINDYUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$134,730CHHD
2015Visual and auditory perceptual factors affecting spatial release from masking1K99DC014288-01MADDOX, ROSS KUNIVERSITY OF WASHINGTON, WA$134,520CDRC
2015Interactions of Centella asiatica, mitochondrial function and oxidative stress during aging1K99AT008831-01GRAY, NORAOREGON HEALTH & SCIENCE UNIVERSITY, OR$134,190ZAT1
2015Investigating the role of the small GTPase RIT1 in lung adenocarcinoma1K99CA197762-01BERGER, ALICEDANA-FARBER CANCER INST, MA$133,108NCI
2015Mass Spectrometry Imaging for Clinical Diagnosis and Prognosis of Human Cancers1K99CA190783-01SCHIAVINATO EBERLIN, LIVIASTANFORD UNIVERSITY, CA$133,083NCI
2015Mitochondrial Iron metabolism in Chronic Obstructive Pulmonary Disease1K99HL125899-01CLOONAN, SUZANNE MWEILL MEDICAL COLL OF CORNELL UNIV, NY$132,381ZHL1
2015Dissection of Complex Multifactorial Interactions between Bacterial Species.1K99AI108787-01A1KHARE, ANUPAMACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$132,300MID
2015SES and ALLOSTATIC Load: Pregnancy Outcomes and Maternal Neurobehavior1K99HD079668-01A1SPICER, JULIE ACOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$132,290CHHD
2015INTEGRATED ANALYSIS & INTERPRETATION OF WHOLE GENOME, EXOME & TRANSCRIPTOME SEQUENCE DATA IN CANCER1K99HG007940-01A1GRIFFITH, MALACHIWASHINGTON UNIVERSITY, MO$132,036GNOM
2015Mechanisms of Non-Canonical NF-kB Activation in Transplant Arteriosclerosis1K99HL125895-01JANE-WIT, DANIELYALE UNIVERSITY, CT$131,895ZHL1
2015Male Germ Cell RNA Binding Proteins and Nuclear RNAs in Male Fertility1K99HD083521-01SNYDER, ELIZABETH M,JACKSON LABORATORY, ME$131,490CHHD
2015Neurobehavioral Study of Warnings for Adolescents at Risk for Nicotine Dependence1K99HD084746-01WANG, AN-LIUNIVERSITY OF PENNSYLVANIA, PA$131,406CHHD
2015Ciliary control of Gli protein activity in Hedgehog pathway signaling1K99HD082280-01BRESLOW, DAVID KINGSTANFORD UNIVERSITY, CA$130,599CHHD
2015Epistatic Regulatory Mechanisms of Coronary Heart Disease Risk1K99HL125912-01MILLER, CLINT LSTANFORD UNIVERSITY, CA$130,599ZHL1
2015Mechanics of fibrosis in 3D biomimetic extracellular matrices1K99HL124322-01A1BAKER, BRENDON MBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$130,356MTI
2015Molecular Mechanisms of Intellectual Disability1K99HD082337-01A1SCHAFFER, ASHLEIGH EUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$130,270CHHD
2015Structural RNA elements and their roles in post-transcriptional regulation1K99CA194077-01GOODARZI, HANIROCKEFELLER UNIVERSITY, NY$129,638NCI
2015Investigating hepatocyte signaling driven by host-pathogen interactions1K99AI111785-01A1KAUSHANSKY, ALEXISSEATTLE BIOMEDICAL RESEARCH INSTITUTE, WA$129,060MID
2015Requirement of hydrogen sulfide for the benefits of dietary sulfur amino acid restriction1K99AG050777-01HINE, CHRISTOPHER MICHAELHARVARD SCHOOL OF PUBLIC HEALTH, MA$128,412NIA
2015Quantitation and biochemical characterization of autophagy's role in aging1K99AG050749-01DAVIS, JOSEPH HARRYSCRIPPS RESEARCH INSTITUTE, THE, CA$128,250NIA
2015Elucidating the function of WNT4 in endocrine response and resistance in invasive lobular carcinoma1K99CA193734-01SIKORA, MATTHEW JUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$128,153NCI
2015Beta-adrenergic signaling modulates mitochondrial function and dynamics1K99HL129474-01A1CORONADO, MICHAEL J.STANFORD UNIVERSITY, CA$127,683MTI
2015Mechanisms of Skeletal Stem Cell Aging1K99AG049958-01A1CHAN, CHARLES KFSTANFORD UNIVERSITY, CA$127,683NIA
2015Brain Systems Underlying Episodic Memory for Social Stimuli in Childhood Autism1K99MH105601-01QIN, SHAOZHENGSTANFORD UNIVERSITY, CA$126,252ZMH1
2015The genetics and neurobiology of parental care in wild mice1K99HD084732-01BENDESKY, ANDRESHARVARD UNIVERSITY, MA$125,352CHHD
2015Autonomic: Angiotensin-(1-7) Interactions in Hypertension1K99HL122507-01A1ARNOLD, AMY CHRISTINEVANDERBILT UNIVERSITY, TN$124,809ZHL1
2015Viral sequence and dynamic determinants of antibody breadth1K99AI120851-01MURRELL, BENJAMIN SYLVESTERUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$124,200AIDS
2015Characterization of breast cancer dormancy in bone1K99CA194198-01JOHNSON, RACHELLE WSTANFORD UNIVERSITY, CA$123,603NCI
2015Hedgehog Pathway Activity and Targeting in KCOT1K99DE023826-01A1AMM, HOPEUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$123,378DSR
2015Investigation of alternative splicing in response to low and disturbed flow1K99HL125727-01A1MURPHY, PATRICK ANDRIESMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$123,361MTI
2015Factors Influencing KSHV Infection and Spread within the Oral Cavity1K99DE024969-01TOTONCHY, JENNIFER EWEILL MEDICAL COLL OF CORNELL UNIV, NY$123,050DSR
2015Ubiquitin-dependent regulation of ribosome function in cell fate determination1K99DE025314-01WERNER, ACHIMUNIVERSITY OF CALIFORNIA BERKELEY, CA$122,580DSR
2015Neural bases of alcohol-related decision-making1K99AA023296-01A1OBERLIN, BRANDONINDIANA UNIVERSITY INDIANAPOLIS, IN$122,370AA
2015Quantifying the Fluctuations of Intrinsic Brain Activity in Healthy and Patient Populations1K99MH104605-01A1SAGGAR, MANISHSTANFORD UNIVERSITY, CA$122,370ZMH1
2015Asynchronous Release in Synaptic Transmission1K99MH107618-01WU, DISTANFORD UNIVERSITY, CA$122,283ZMH1
2015Adaptive regulation of cancer cell fate following oncogene inhibition1K99CA194163-01FALLAHI-SICHANI, MOHAMMADHARVARD MEDICAL SCHOOL, MA$120,183NCI
2015DEPTOR/miR-181d, a novel tumor-suppressor axis for prognosis and treatment of breast cancer1K99CA194274-01GOGNA, RAJANDARTMOUTH COLLEGE, NH$119,232NCI
2015Centrosomes and Cytoskeletal Mechanisms of Blood Vessel Dysfunction1K99HL124311-01A1KUSHNER, ERICH JUNIV OF NORTH CAROLINA CHAPEL HILL, NC$119,136MTI
2015The Family Environment, Social Support, and Health in Transgender Youth1K99HD082340-01KATZ-WISE, SABRA L.BOSTON CHILDREN'S HOSPITAL, MA$119,074CHHD
2015Understanding Photoreceptor Trafficking Pathways to the Outer Segment1K99EY025732-01PEARRING, JILLIAN NYDAMDUKE UNIVERSITY, NC$118,605ZEY1
2015A Novel Intravascular CRI-PAT Imaging System to Characterize Vulnerable Plaque1K99HL127180-01ZAMAN, RAIYAN TRIPTISTANFORD UNIVERSITY, CA$118,167MTI
2015Physiological role of the TNKS-PI31 dependent proteasome regulation1K99CA190658-01A1CHO, PAKROCKEFELLER UNIVERSITY, NY$118,139NCI
2015The control of the breast cancer stem cell state by snail-driven EMT program1K99CA194160-01YE, XINWHITEHEAD INSTITUTE FOR BIOMEDICAL RES, MA$116,651NCI
2015Targeting Wnt signaling to overcome PARP inhibitor resistance in ovarian cancer1K99CA194318-01BITLER, BENJAMIN GWISTAR INSTITUTE, PA$115,014NCI
2015Nucleotide Metabolism in Senescence and Platinum Resistance of Ovarian Cancer1K99CA194309-01AIRD, KATHERINE MARIEWISTAR INSTITUTE, PA$115,014NCI
2015Cell Biological Mechanisms of Melanoma Cell Motility in vivo1K99CA190836-01A1ROH, MINNAFRED HUTCHINSON CANCER RESEARCH CENTER, WA$114,372NCI
2015The role of excitatory inputs to BNST CRF neurons in alcohol drinking behavior1K99AA023559-01PLEIL, KRISTEN ELIZABETHUNIV OF NORTH CAROLINA CHAPEL HILL, NC$114,169AA
2015Mitochondrial Markers of Pollution, Stress, and Neurobehavior1K99ES024116-01A1BRUNST, KELLY JICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$113,823ZES1
2015Dissection of the anxiety suppression circuitry1K99MH106649-01ADHIKARI, AVISHEKSTANFORD UNIVERSITY, CA$113,694ZMH1
2015Investigation of luminal stem cells and castration resistance in prostate cancer1K99CA194287-01SHIBATA, MAHOCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$112,770NCI
2015Opiate abuse and sex steroids influence neuroAIDS pathology1K99DA039791-01A1PARIS, JASON RICHARDVIRGINIA COMMONWEALTH UNIVERSITY, VA$112,722ZDA1
2015The role of PRDM1 in epigenetic regulation and tumor suppression1K99CA190803-01CARLSON, SCOTT MOORESTANFORD UNIVERSITY, CA$112,614NCI
2015Novel role of central AT2R in blood pressure regulation1K99HL125805-01DE KLOET, ANNETTE DIANEUNIVERSITY OF FLORIDA, FL$112,253ZHL1
2015The Importance of Inhomogeneity in the Pathogenesis of Lung Injury1K99HL128944-01SMITH, BRADFORD JUNIVERSITY OF VERMONT & ST AGRIC COLLEGE, VT$111,770MTI
2015Dysregulation of Neuronal Guidance Cue Netrin-1 in Accelerated AAA1K99HL125667-01RAMKHELAWON, BHAMANEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$110,698ZHL1
2015GREB1 Action in Endometrial Function and Dysfunction1K99HD080742-01A1KOMMAGANI, RAMAKRISHNABAYLOR COLLEGE OF MEDICINE, TX$110,696CHHD
2015Massively Parallel Phenotypic Characterization of Non-coding Genetic Variation1K99HG008179-01TEWHEY, RYANHARVARD UNIVERSITY, MA$109,974GNOM
2015Development of mosaic mouse models of HCC for genetic interspecies inference1K99CA191152-01FONT-BURGADA, JOANUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$109,620NCI
2015Redox Regulation of T-lymphocytes in Sympathoexcitation-associated Hypertension1K99HL123471-01A1CASE, ADAM JUNIVERSITY OF NEBRASKA MEDICAL CENTER, NE$108,000MTI
2015Defining the Tendon Lineage to Improve Tissue Engineering Strategies1K99AR067283-01A1DYMENT, NATHANIEL A.UNIVERSITY OF CONNECTICUT SCH OF MED/DNT, CT$108,000AMS
2015Promoting Healthy Development among Children of Fathers with Antisocial Behavior1K99HD081273-01A1CHARLES, PAJARITAUNIVERSITY OF CHICAGO, IL$105,869CHHD
2015Structure-function Analysis of Bestrophins1K99EY025290-01YANG, TINGTINGCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$105,840ZEY1
2015Molecular basis of HIV restriction by SAMHD11K99AI120845-01JI, XIAOYUNYALE UNIVERSITY, CT$104,695AIDS
2015Hypoxia induces SHMT2 to regulate cellular redox and epigenetics1K99CA184239-01A1YE, JIANGBINSLOAN-KETTERING INST CAN RESEARCH, NY$104,417NCI
2015Bacterial Sensing and Response to Chloride as a Novel Tuberculosis Drug Target1K99AI114952-01A1TAN, SHUMINCORNELL UNIVERSITY, NY$103,648MID
2015Discovering disease-causal variants by linking genetic and epigenetic variation1K99HG008399-01PINELLO, LUCADANA-FARBER CANCER INST, MA$103,198GNOM
2015Defining the roles of ubiquitination during the environmental stress response1K99ES025835-01SILVA, GUSTAVO MNEW YORK UNIVERSITY, NY$102,705ZES1
2015The Role of Language Experiences on Vocabulary Development: a Multidimensional, Developmental, and Individual Differences Analysis1K99HD082358-01SUANDA, SUMARGA HAVELINTRUSTEES OF INDIANA UNIVERSITY, IN$102,588CHHD
2015Notch signaling in cardiomyocyte transcriptome signatures1K99HL128906-01CHURKO, JAREDSTANFORD UNIVERSITY, CA$102,513MTI
2015Systems Based Analysis of Host Factors that Contribute to Aging Pathogenesis1K99AG049092-01A1MENACHERY, VINEET DUNIV OF NORTH CAROLINA CHAPEL HILL, NC$101,494NIA
2015Modulators of DNA damage associated nucleo-mitochondrial communication in aging1K99AG049126-01GURKAR, ADITI USCRIPPS FLORIDA, FL$101,250NIA
2015The mechanics and dynamics of RNP granules1K99HD081208-01A1AOKI, SCOTT TUNIVERSITY OF WISCONSIN-MADISON, WI$101,199CHHD
2015Scaffold-free Tissue Engineering: Using Principles from Developmental Biology to Support Craniofacial Regeneration1K99DE025088-01SYED, FATIMA NAZUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$101,195DSR
2015Learning about Early Childhood Caries Prevention in a Latino Population: A Multilevel Approach1K99DE024758-01A1TIWARI, TAMANNAUNIVERSITY OF COLORADO DENVER, CO$101,114ZDE1
2015Neural markers of speech error detection and correction abilities in aphasia1K99DC014520-01NIZIOLEK, CAROLINEBOSTON UNIVERSITY (CHARLES RIVER CAMPUS), MA$100,038ZDC1
2015Genome engineering tools for functional screening of non-coding elements1K99HG008171-01SANJANA, NEVILLEBROAD INSTITUTE, INC., MA$99,937GNOM
2015Identifying selective visual attention mechanisms through high-dimensional analysis.1K99EY025768-01SNYDER, ADAM CHRISTOPHERCARNEGIE-MELLON UNIVERSITY, PA$99,536ZEY1
2015Endocrine Disruptors: Maternal Estrogen, Metabolism and Fetal Fatty Acid Supply1K99ES024795-01A1STRAKOVSKY, RITA S.UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN, IL$99,161ZES1
2015Alternative splicing-mediated mechanisms of cortical interneuron maturation and circuit integration1K99MH107684-01JAGLIN, XAVIERNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$98,061ZMH1
2015Regulation of cancer cell metabolism and growth by the pancreatic tumor stroma1K99CA188259-01A1SHERMAN, MARA H.SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$97,557NCI
2015Statistical methods for inferring recent human demographic and evolutionary history1K99HG008122-01A1FU, WENQINGUNIVERSITY OF WASHINGTON, WA$97,429GNOM
2015Engineering Synthetic Receptor Systems That Can Detect Specific Cell-Cell Contact Signals1K99EB021030-01MORSUT, LEONARDOUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$97,254ZEB1
2015Linking oncogenic signaling to tumor metabolism1K99CA194192-01BEN-SAHRA, ISSAMHARVARD SCHOOL OF PUBLIC HEALTH, MA$97,252NCI
2015The role of the small molecular chaperone HSP25 in longevity and healthy aging1K99AG049940-01A1RODRIGUEZ, KARL AUNIVERSITY OF TEXAS HLTH SCIENCE CENTER, TX$97,200NIA
2015The development and application of tools to characterize the 4D nucleome1K99HG008662-01PHANSTIEL, DOUGLAS H.STANFORD UNIVERSITY, CA$96,951GNOM
2015Drug discovery and mechanistic study of P23H rhodopsin associated retinitis pigmentosa1K99EY024992-01CHEN, YUANYUANCASE WESTERN RESERVE UNIVERSITY, OH$96,390ZEY1
2015Analysis of an ethanol-sensitive pathway regulating anterior craniofacial development1K99AA023560-01A1LOVELY, CHARLES BENJAMINUNIVERSITY OF TEXAS AT AUSTIN, TX$96,118AA
2015Protein S Anticoagulant Activity: Biochemical Mechanisms and Structural Studies1K99HL129193-01WOOD, JEREMY PVERSITI WISCONSIN, INC., WI$95,881MTI
2015Regulation of transcriptional consistency by broad H3K4me3 domains in young cells and during aging1K99AG049934-01BENAYOUN, BERENICE ANATHSTANFORD UNIVERSITY, CA$95,377NIA
2015Molecular Programming of Immunological Memory in Human Natural Killer Cells1K99HL123638-01A1CICHOCKI, FRANKUNIVERSITY OF MINNESOTA, MN$95,176MTI
2015Parietal-hippocampal network in the triple transgenic mouse model of Alzheimers1K99AG049090-01A1WILBER, AARON AUNIVERSITY OF CALIFORNIA-IRVINE, CA$95,172NIA
2015In vivo investigation of mitochondrial dynamics in the mouse brain1K99NS091526-01LEWIS, TOMMY LCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$94,982NST
2015Thalamic circuits in the integration of fear and reward1K99MH105549-01DO MONTE, FABRICIO HOFFMANNUNIVERSITY OF PUERTO RICO MED SCIENCES, PR$94,540ZMH1
2015Stimulated Raman imaging for label-free histology to guide brain tumor surgery1K99EB020749-01LU, FAKEBRIGHAM AND WOMEN'S HOSPITAL, MA$94,500ZEB1
2015Cholinergic modulation of cortical visual processing1K99EY025026-01JADI, MONIKA P.SALK INSTITUTE FOR BIOLOGICAL STUDIES, CA$94,392ZEY1
2015Nucleocentric molecular characterization of C9orf72 NRE-linked neurodegeneration1K99NS091486-01HAEUSLER, AARON RAYMONDJOHNS HOPKINS UNIVERSITY, MD$94,230NST
2015Structural investigations of native and mutant human green cone pigment1K99EY025007-01ALEXANDER, NATHANCASE WESTERN RESERVE UNIVERSITY, OH$94,133ZEY1
2015Genetics of Craniofacial Disorders and Related Phenotypes1K99DE025060-01LESLIE-CLARKSON, ELIZABETH JANEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$93,927DSR
2015Neuroimaging of deep brain stimulation patients using safe MRI excitations1K99EB019482-01A1GUERIN, BASTIENMASSACHUSETTS GENERAL HOSPITAL, MA$93,831ZEB1
2015Mechanisms of spatial memory during navigation in virtual reality1K99NS093071-01ARONOV, DMITRIYPRINCETON UNIVERSITY, NJ$93,690NST
2015Construction of Relation Detection Framework Empowered by Topic Modeling1K99LM012021-01LI, DING CHENGMAYO CLINIC ROCHESTER, MN$93,654BLR
2015Microdomain regulation of Ca2+ release in cardiac physiology and disease1K99HL127299-01RADWANSKI, PRZEMYSLAWOHIO STATE UNIVERSITY, OH$93,636MTI
2015iNKT cells regulate IL-4 homeostasis and autoimmunity1K99AI114884-01A1LEE, YU-JUNGUNIVERSITY OF MINNESOTA, MN$93,510AITC
2015Complete Phasing of Methylome in Multiple Human Cell Types and Individuals1K99HG007841-01A1XIE, DANSTANFORD UNIVERSITY, CA$93,308GNOM
2015Mechanisms of C9orf72 hexanucleotide repeat expansion caused neurodegeneration in ALS and FTD1K99NS091538-01SUN, SHUYINGLUDWIG INSTITUTE FOR CANCER RES LTD, CA$93,042NST
2015Post-transcriptional Regulation of Satellite Cell Function1K99AR066696-01A1DOLES, JASONUNIVERSITY OF COLORADO, CO$92,988AMS
2015Th9 cells as a promising effector T-cell subset for cancer therapy1K99CA190910-01LU, YONGCLEVELAND CLINIC LERNER COM-CWRU, OH$92,275NCI
2015DNA Topological and Epigenetic Regulation in Neurodevelopment and Disorders1K99NS091508-01TEE, WEE WEINEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$92,015NST
2015Fracture Prediction by Machine Learning and 3D Finite Element Models from DXA1K99AR067883-01NISHIYAMA, KYLE KCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$91,800AMS
2015Pathogenesis of polymicrobial catheter-associated urinary tract infection1K99DK105205-01ARMBRUSTER, CHELSIE ELIZABETHUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$91,500DDK
2015Circulating Factors that Regulate Brown and Beige Fat1K99DK105203-01LONG, JONATHAN ZDANA-FARBER CANCER INST, MA$91,500DDK
2015The role of RHO GTPases and of coenzyme Q10 in nephrotic syndrome1K99DK105335-01GEE, HEON YUNGBOSTON CHILDREN'S HOSPITAL, MA$91,500DDK
2015Non-hypertensive cardiac disorders in polycystic kidney disease1K99DK101585-01A1KUO, IVANA YYALE UNIVERSITY, CT$91,500DDK
2015The genetic identity of the primary cilia ion channels of kidney collecting duct cells and their regulation by internal calcium1K99DK106655-01DECAEN, PAUL GREGORYBOSTON CHILDREN'S HOSPITAL, MA$91,500DDK
2015Microcystin-LR toxicity in nonalcoholic steatohepatitis1K99ES024455-01A1CLARKE, JOHN DANIELUNIVERSITY OF ARIZONA, AZ$91,383ZES1
2015Health and Well-Being after Large Scale Shocks1K99HD083519-01HO, JESSICA YUDUKE UNIVERSITY, NC$91,099CHHD
2015Mechanisms of Carotenoid Transport and Interactions with Nutrient Absorption1K99AT008576-01MORAN, NANCY EOHIO STATE UNIVERSITY, OH$90,431ZAT1
2015Crystallographic and NMR studies of the Human Cytochrome P450 enzyme responsible for inactivating vitamin D1K99GM112862-01ESTRADA, DAVID FERNANDOUNIVERSITY OF KANSAS LAWRENCE, KS$90,000ZGM1
2015Understanding Epstein Barr virus oncogenicity through non-coding RNA structure1K99GM112877-01MOSS, WALTERYALE UNIVERSITY, CT$90,000ZGM1
2015Structure and mechanism of cytoplasmic and axonemal dyneins1K99GM112982-01BHABHA, GIRAUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$90,000ZGM1
2015Regulation of Chromatin by Histone Phosphorylation1K99GM113019-01JOSEFOWICZ, STEVEN ZVIROCKEFELLER UNIVERSITY, NY$90,000ZGM1
2015Structural mechanisms for ABC multidrug transporter selectivity and transport1K99GM114245-01TOMASIAK, THOMAS MICHAELUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$90,000ZGM1
2015Delineation of a cytokine gene regulatory network and rewiring in disease1K99GM114296-01FUXMAN BASS, JUAN IGNACIOUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$90,000ZGM1
2015Antimicrobial peptides as models for the evolution of gene duplication1K99GM114714-01UNCKLESS, ROBERT LCORNELL UNIVERSITY, NY$90,000ZGM1
2015Mechanisms of meiotic drive and the functional consequences of rapid genome evolution in Schizosaccharomyces1K99GM114436-01ZANDERS, SARAH ELIZABETHFRED HUTCHINSON CANCER RESEARCH CENTER, WA$90,000ZGM1
2015RNAs that Resist Degradation in the Cell and the Manipulation of RNA Stability in Living Organisms1K99GM115757-01CHAPMAN, ERICH GUNIVERSITY OF COLORADO DENVER, CO$90,000ZGM1
2015Elucidating how intracellular bacterial pathogens hijack host intercellular communication to promote spread1K99GM115765-01LAMASON, REBECCA LUNIVERSITY OF CALIFORNIA BERKELEY, CA$90,000ZGM1
2015Deciphering GPCR signal transduction through NMR structure and dynamics studies1K99GM115814-01ZIAREK, JOSHUA JAMESHARVARD MEDICAL SCHOOL, MA$90,000ZGM1
2015The Role of IRF4 in Exercise Induced Thermogenesis1K99DK106550-01KONG, XINGXINGBETH ISRAEL DEACONESS MEDICAL CENTER, MA$90,000DDK
2015Biochemical Basis of Cell Polarization by the PAR Protein System1K99GM115964-01DICKINSON, DANIEL JUNIV OF NORTH CAROLINA CHAPEL HILL, NC$90,000ZGM1
2015Causes and human health consequences of the evolution of retroelements and host restriction factors1K99GM112941-01A1MCLAUGHLIN, RICHARD NOELFRED HUTCHINSON CANCER RESEARCH CENTER, WA$90,000ZGM1
2015Adaptive evolution of bacteria in the battle for iron1K99GM115822-01BARBER, MATTHEW FREDERICKUNIVERSITY OF UTAH, UT$89,999ZGM1
2015THE ROLE OF RNA METHYLATION IN THE REGULATION OF lncRNA FUNCTION1K99GM115868-01CIFUENTES-ROJAS, CATHERINEMASSACHUSETTS GENERAL HOSPITAL, MA$89,996ZGM1
2015Advancing Our Understanding of Oligomer Toxicity in Age-Related Amyloid Disorders1K99AG050764-01EISELE, YVONNE SIMONESCRIPPS RESEARCH INSTITUTE, THE, CA$89,975NIA
2015Multimodal Peptide Amphiphile Micelles for Atherosclerosis1K99HL124279-01A1CHUNG, EUN JI PAIGEUNIVERSITY OF CHICAGO, IL$89,964MTI
2015Fluoride and human health: Assessing novel biomarkers in detecting bone disorder1K99ES023472-01A1GODEBO, TEWODROS RDUKE UNIVERSITY, NC$89,950ZES1
2015Disease-Induced Modification in Nanoparticle-Corona Identity and Toxicity1K99ES024392-01A1SHANNAHAN, JONATHAN HENRYUNIVERSITY OF COLORADO DENVER, CO$89,906ZES1
2015Smart Walk: A Smartphone Physical Activity Program for African American Women1K99HL129012-01JOSEPH, RODNEYARIZONA STATE UNIVERSITY-TEMPE CAMPUS, AZ$89,534MTI
2015Opioid effects on respiratory-controlling pontine neurons1K99DA038069-01A1LEVITT, ERICA SAWYEROREGON HEALTH & SCIENCE UNIVERSITY, OR$89,515ZDA1
2015Meiotic checkpoint pathways and gametocyte quality control1K99HD082375-01A1QIAO, HUANYUUNIVERSITY OF CALIFORNIA AT DAVIS, CA$89,078CHHD
2015Organization and Dynamics of Premotor and Prefrontal Cortical Circuits Mediating Goal-Directed Behavior1K99NS092972-01CHANDRASEKARAN, CHANDRAMOULISTANFORD UNIVERSITY, CA$88,678NST
2015Mechanically controlled release of hematopoietic factors from mesenchymal stromal cells for blood regeneration1K99HL125884-01SHIN, JAE-WONHARVARD UNIVERSITY, MA$88,453ZHL1
2015Molecular Mechanisms of microRNA and miRISC turnover1K99GM113063-01MCJUNKIN, KATHERINEUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$88,305ZGM1
2015Regulation of Cytoplasmic Dynein Motility in Neuronal Transport1K99NS089428-01A1MCKENNEY, RICHARD JAMESUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$88,020NST
2015Coherence-Based Photoacoustic Image Guidance of Transsphenoidal Surgeries1K99EB018994-01A1BELL, MUYINATU A. LEDIJUJOHNS HOPKINS UNIVERSITY, MD$87,925ZEB1
2015Migration and Child Development1K99HD079586-01A1DAVIS, JASONUNIV OF NORTH CAROLINA CHAPEL HILL, NC$87,134CHHD
2015Mechanisms of anti-inflammation and membrane stabilization in muscular dystrophy1K99HL130035-01A1HEIER, CHRISTOPHER RYANCHILDREN'S RESEARCH INSTITUTE, DC$86,940MTI
2015Prefrontal Cortical Circuitry Attenuates Cardiovascular Stress Reactivity1K99HL122454-01A1MYERS, BRENT PHILIPUNIVERSITY OF CINCINNATI, OH$86,860ZHL1
2015Functional Dissection of Autophagosome Biogenesis1K99GM114397-01GE, LIANGUNIVERSITY OF CALIFORNIA BERKELEY, CA$86,400ZGM1
2015Integrative Analyses to Identify Pancreatic Cancer Susceptibility Genes1K99CA190889-01ROBERTS, NICHOLAS JASONJOHNS HOPKINS UNIVERSITY, MD$86,161NCI
2015Mitochondrial Mechanisms, Microvascular Function, and Gestational Nanotoxicology1K99ES024783-01STAPLETON, PHOEBEWEST VIRGINIA UNIVERSITY, WV$86,157ZES1
2015Learning Patterns of Collaboration to Optimize the Management of Care Providers1K99LM011933-01A1CHEN, YOUVANDERBILT UNIVERSITY, TN$85,959BLR
2015Ethical Legal and Social Implications of Translational Psychiatric Genomics Research1K99HG008689-01LAZARO-MUNOZ, GABRIELUNIV OF NORTH CAROLINA CHAPEL HILL, NC$85,099SEIR
2015Programmable Probiotics for Cancer1K99CA197649-01DANINO, TALMASSACHUSETTS INSTITUTE OF TECHNOLOGY, MA$84,741NCI
2015Improving the control of fear: healthy adults to pathological anxiety1K99MH106719-01DUNSMOOR, JOSEPH EDWARDNEW YORK UNIVERSITY, NY$84,015ZMH1
2015Developing and Assessing a Male Engagement Intervention for Option B+ in Malawi1K99MH104154-01A1ROSENBERG, NORAUNIV OF NORTH CAROLINA CHAPEL HILL, NC$83,991ZMH1
2015Type VI Secretion System MIX-effectors and their use as anti-bacterial agents1K99AI116948-01SALOMON, DOR SAMUELUT SOUTHWESTERN MEDICAL CENTER, TX$83,917MID
2015New tools for imaging: diagnostics based on therapeutics1K99EB020075-01BRUGAROLAS, PEDROUNIVERSITY OF CHICAGO, IL$83,718ZEB1
2015Emotional modulation of human memory processes and corticohippocampal systems1K99MH103401-01A1RITCHEY, MAUREENUNIVERSITY OF CALIFORNIA AT DAVIS, CA$83,546ZMH1
2015Regulation of VTA inhibitory synapses by acute and chronic stress1K99MH106757-01POLTER, ABIGAIL MARIEBROWN UNIVERSITY, RI$75,591ZMH1
2015Long-term Effects of Early-Life Arsenic Exposure on Immunity1K99ES024808-01A1SILLE, FENNAUNIVERSITY OF CALIFORNIA BERKELEY, CA$70,918ZES1
2015Nuclear Factor I/B Action in Castrate Resistant Prostate Cancer1K99CA197315-01GRABOWSKA, MAGDALENA MALGORZATAVANDERBILT UNIVERSITY, TN$69,814NCI
2015Identifying the Receptors of Environmentally Sensitive Epoxy-Eicosanoids with AMS1K99ES024806-01LEE, KIN SING STEPHENUNIVERSITY OF CALIFORNIA AT DAVIS, CA$66,780ZES1
2015A chemical biology approach towards understanding the anti-cancer innate immunity1K99CA190896-01LI, LINGYINHARVARD MEDICAL SCHOOL, MA$47,346NCI
2014Assessing Dynamic Opioid-Dopamine Interactions Using Simultaneous PET/MRI1K99DA037928-01 · under PA-11-197WEY, HSIAO-YINGMASSACHUSETTS GENERAL HOSPITAL, MA$187,164ZDA1
2014A role for notch in self renewal in embryonal rhabdomyosarcoma1K99CA175184-01A1 · under PA-11-197IGNATIUS, MYRON STEVEMASSACHUSETTS GENERAL HOSPITAL, MA$180,360NCI
2014The Role of EglN1 and HIF in Normal Hematopoiesis and in Leukemia1K99CA181488-01 · under PA-11-197LOSMAN, JULIE-AUROREDANA-FARBER CANCER INST, MA$176,720NCI
2014Targeting Determinants of OvCa Metastases in Engineered 3D Microfluidic Platforms1K99CA175292-01A1 · under PA-11-197RIZVI, IMRANBRIGHAM AND WOMEN'S HOSPITAL, MA$174,871NCI
2014The role of the protein tyrosine phosphatase PRL3 in leukemia development1K99CA181500-01 · under PA-11-197BLACKBURN, JESSICA S.MASSACHUSETTS GENERAL HOSPITAL, MA$172,962NCI
2014Innovative Smartphone Application for Quitting Smoking among Seriously Mentally I1K99DA037276-01 · under PA-11-197VILARDAGA, ROGERUNIVERSITY OF WASHINGTON, WA$172,179ZDA1

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