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NIH funding notice PA-14-072

PHS 2014-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]

Closed on May 7, 2015.

Posted
January 17, 2014
Close date
May 7, 2015
Activity codes
R41, R42
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, ORIP

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-13-235 Reissue PHS 2013-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  2. 2 steps back: PA-13-089 PHS 2013-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  3. 3 steps back: PA-12-089 PHS 2012-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  4. 4 steps back: PA-11-097 PHS 2011-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  5. 5 steps back: PA-10-051 PHS 2010-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  6. 6 steps back: PA-09-081 PHS 2009-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])

Replaced by PA-15-270.

Who won it before

387 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $119,622,286 in first-year total cost, median $224,991.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ETTN-M (11)]34
  2. Special Emphasis Panel[ZRG1 SBIB-T (10)]27
  3. Special Emphasis Panel[ZRG1 OTC-T (10)]26
  4. Special Emphasis Panel[ZRG1 IMST-L (11)]17
  5. Special Emphasis Panel[ZRG1 IMST-M (13)]17

Most frequent institutions

  1. BARRON ASSOCIATES, INC.4
  2. CORTICOMETRICS, LLC4
  3. FOX CHASE CHEMICAL DIVERSITY CENTER, INC4
  4. MICROBIOTIX, INC4
  5. COG ANALYTICS, LLC3
Competing awards under PA-14-072 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2017Peripheral FAAH as a target for novel analgesics2R42DA033683-02A1PIOMELLI, DANIELEANTEANA THERAPEUTICS, INC., CA$1,100,244ZRG1
2016The Allogeneic Heart Stem Cell Trial in Hypoplastic Left Heart Syndrome Patients1UT2HL131226-01RODRIGUEZ-BORLADO, LUISCAPRICOR, INC., CA$1,683,381ZRG1
2016New generation of catheters for treatment of atrial fibrillation2R42HL120511-02SARVAZYAN, NARINENOCTURNAL PRODUCT DEVELOPMENT, LLC, NC$1,173,082ZRG1
2016Preclinical Testing of a Novel Flow Diverting Stent for Treating Intracranial Aneurysms2R42NS074576-03KALLMES, DAVID FKEALEY, COLIN PATRICKNEUROSIGMA, INC., CA$1,072,694ZRG1
2016A Phase 2a clinical trial of ALK-001 in geographic atrophy2R44EY021988-02A1SAAD, LEONIDEWASHINGTON, ILYASALKEUS PHARMACEUTICALS, INC., MA$1,054,287ZRG1
2016Clonotyping Technology for Prediction of Antibiotic Resistance2R42AI116114-02KAWASAKI, GLENNOSTER, JEFFREYSOKURENKO, EVGENI VENIAMINOVICIDGENOMICS, INC., WA$999,967ZRG1
2016SMALL MOLECULE ANTAGONISTS OF PF4 FOR THE TREATMENT AND PREVENTION OF HIT2R42HL123126-02SACHAIS, BRUCE SFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$980,000ZRG1
2016Mutation Enriched Targeted Re-Sequencing2R42CA180389-02A1MAKRIGIORGOS, G. MIKEWU, GRANTTRANSGENOMIC, INC., NE$773,511ZRG1
2016The CellRaft AIR System: Workflow Automation for Stem Cell Isolation and Recovery2R42GM106421-02ALLBRITTON, NANCY L.CELL MICROSYSTEMS, INC., NC$748,655ZRG1
2016Memory Care Partner2R42AG044147-02A1ANDERSEN, TROYFOSTER, NORMAN LOUISPROACTIVE MEMORY SERVICES, INC., UT$734,115ZRG1
2016Development of small near-infrared laser system capable of improving immune responses to vaccines (laser-based adjuvant)2R42AI114012-02BEAN, DAVIDVERALASE, LLC, MA$696,264ZRG1
2016Single Cell Analysis via Nanoscale Tip-Enhanced Laser Ablation Mass Spectrometry2R42GM106454-02MURRAY, KERMIT KINGANASYS INSTRUMENTS CORPORATION, CA$597,820ZRG1
2016High-potency nitro antimicrobials for topical treatment of trichomoniasis1R41AI118089-01A1ECKMANN, LARSPEYTON, DAVID HDESIGNMEDIX, INC., OR$353,902ZRG1
2016A microfluidic quality-control assay for stem-cell derived therapies1R41TR001203-01A1NEUMANN, THOMASNORTIS, INC., WA$325,000ZRG1
2016T3SS needle protein inhibitors for the treatment of P. aeruginosa infection1R41AI122433-01MECSAS, JOAN CMICROBIOTIX, INC, MA$302,983ZRG1
2016Combinatorial Inactivation of ERBB Receptors in Breast Cancer using Therapeutic Stapled Peptides1R41CA203353-01SCHROEDER, JOYCE AARIZONA CANCER THERAPEUTICS, LLC, AZ$300,000ZRG1
2016Antibody targeting of ADAM8 for treatment of triple-negative breast cancer1R41CA200161-01A1SONENSHEIN, GAIL E.ADECTO PHARMACEUTICALS, INC., MA$300,000ZRG1
2016Small molecule inhibitors targeting oncogenic drivers of hepatocellular carcinoma1R41CA195908-01A1WAJAPEYEE, NARENDRAL2 DIAGNOSTICS, LLC, CT$298,959ZRG1
2016Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development1R41CA203090-01UNGER, EVAN CHARLESWILLMANN, JUERGEN KARLNUVOX PHARMA, LLC, AZ$297,786ZRG1
2016Novel antibacterial agents derived from natural products1R41AI118104-01A1PRIESTLEY, NIGEL DPROMILIAD BIOPHARMA, INC., MT$295,729ZRG1
2016Small Molecule Antibiotic Potentiators for Drug-Resistant Bacteria1R41AI115915-01A1JUNG, DAVIDAGILE SCIENCES, INC., NC$294,309ZRG1
2016Development of Optimized AAV Serotype Vectors for Human Gene Therapy1R41AI122735-01SRIVASTAVA, ARUNMEDOSOME BIOTEC, LLC, FL$294,094ZRG1
2016A Novel STAT3 Inhibitor Targeting its DNA-Binding Site for Drug Development1R41CA195777-01A1LIU, JASMINE JINGYUANQRKANSWER, IN$279,838ZRG1
2016Novel SCD1 inhibitors for treatment of cancer1R41CA195946-01A1COPLAND, JOHN A.HAZLEHURST, LORIMODULATION THERAPEUTICS, INC., WV$279,000ZRG1
2016An epitope-focused nanoparticle vaccine for MRSA and biodefense1R41AI122594-01OSCHERWITZ, JONWHITACRE, DAVID CVLP BIOTECH, INC., CA$273,748ZRG1
2016Digital Gene Expression Analysis by 3’ End Sequencing1R41HG008921-01TIAN, BINTOLOUE, MASOUDBIOO SCIENTIFIC CORPORATION, TX$270,000ZRG1
2016Targeted Polymerized Shell Microbubbles to Image Surgical Adhesions1R41GM116530-01A1NAGY, JON OWENWONG, JOYCE YNANOVALENT PHARMACEUTICALS, INC., MT$238,728ZRG1
2016Biological super-resolution imaging using high-index microspheres for cancer research application1R41GM117844-01CARABE-FERNANDEZ, ALEJANDRODARAFSHEH, ARASHLEE, DAEYEONSPHEREVIS, LLC, PA$233,419ZRG1
2016Optimizing Vaccines by Targeting Dendritic Cells with IFNa and IFNb Inducing Adjuvants1R41AI118522-01A1DANLEY, DAVID LAWRENCEPARABON NANOLABS, INC., VA$230,000VACC
2016Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease1R41AI122403-01AMAN, M JAVADLAI, JONATHAN R.INTEGRATED BIOTHERAPEUTICS, INC., MD$229,991ZRG1
2016PEGYLATED PEPTIDES LIGANDS TARGETING RADIATION-INDUCIBLE RECEPTORS ON CANCER1R41CA196002-01A1DEVANATHAN, SRIRAMMEDICAL GUIDANCE SYSTEMS, LLC, MO$225,000ZRG1
2016Aerosol Sampling and Microfluidic Analysis of Reactive Oxygen Species1R42ES026532-01ZYUZIN, ALEXEIILLIONIX, LLC, WA$225,000ZRG1
2016Smaller, Brighter Probes for Correlative Super-resolution and Electron Microscopy1R41GM117974-01POWELL, RICHARD DENISNANOPROBES, INC., NY$225,000ZRG1
2016Repurposing Pyrvinium as an Orphan Drug for Familial Adenomatous Polyposis1R41CA196011-01A1ORTON, DARRENSTEMSYNERGY THERAPEUTICS, INC., FL$224,991ZRG1
2016Therapeutic Potential of the Potassium Channel Inhibitor SHK-186 for Pediatric Lupus1R41AI122566-01PROBST, PETERSTEVENS, ANNE MARGUERITEKINETA, INC., WA$224,977ZRG1
2016Peripheral Nerve-on-a-chip for Predictive Preclinical Pharmaceutical Testing1R41TR001270-01A1CURLEY, JABE LMOORE, MICHAEL JAXOSIM, INC., LA$224,859ZRG1
2016Development of DRα1-MOG-35-55 for treatment of DR2 negative MS subjects1R41AI122574-01VANDENBARK, ARTHUR A.VIROGENOMICS BIODEVELOPMENT, INC., OR$224,796ZRG1
2016Shape RNA Structure Analysis for Drug Discovery and Translational Research1R43GM116274-01WARNER, KATHERINE DEIGANRIBOMETRIX, LLC, NC$224,700ZRG1
2016Assessment of the glucagon receptor blocker REMD-477 on insulin requirements in type 1 diabetes1R42DK108305-01KLEIN, SAMUELTHAI, DUNG LREMD BIOTHERAPEUTICS, INC., CA$224,664ZRG1
2016SHAPE RNA Bioinformatics for Therapeutics and Translational Research1R41GM117712-01WEEKS, KEVIN MRIBOMETRIX, LLC, NC$224,636ZRG1
2016Device for Treatment of Congenital Diaphragmatic Hernia1R41HL131250-01GOLDMAN, KENNETH GLENH-CUBED, INC., OH$224,634ZRG1
2016improving Cas9 mediated homologous recombination in pluripotent stem cells1R41GM115028-01A1ZHANG, JIFENGAPPLIED STEMCELL, INC., CA$224,518ZRG1
2016Engineering stem cells to make mucopolysaccharidosis IIIB1R41NS092221-01A1EKINS, SEANPHOENIX NEST, INC., NY$224,469ZRG1
2016Novel therapies for inherited muscle diseases1R41AR068158-01A1KANG, PETER B.MEDOSOME BIOTEC, LLC, FL$224,463ZRG1
2016New piperazines effecting Abeta oligomer displacement from neuronal receptors1R41AG052252-01IZZO, NICHOLAS JOHNCOGNITION THERAPEUTICS, INC., PA$224,002ZRG1
2016Lipidated Stable BAM8-22 Offers a Promising Therapeutic for Neuropathic Pain1R41NS095436-01KOPIN, ALAN SON TARGET THERAPEUTICS, LLC, MA$223,900ZRG1
2016Dual-view endoscopic probe1R41CA203212-01BANERJEE, BHASKARCOOMBS, DAVIDOMNISCIENT IMAGING, INC., AZ$223,761ZRG1
2016Sample-free onsite detection of cocaine using microneedles via laser-treated skin1R41DA041003-01WU, MEI XXIE, XINMIN SIMONAFASCI, INC., CA$223,633ZRG1
2016Delivery of pathogen-trapping antibodies for vaginal protection1R41AI122472-01MOENCH, THOMAS RAYMUCOMMUNE, LLC, NC$222,725ZRG1
2016An eHealth solution for posttraumatic stress and pain screening integrated in pediatric injury care1R41HD087021-01KASSAM-ADAMS, NANCYMCLAUGHLIN, JEFFERYRADIANT CREATIVE GROUP, LLC, TX$220,945ZRG1
2016A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes1R41AR068202-01A1LOTZ, JEFFREY C.BIONIKS, INC., CA$215,600MRS
2016Optimization of a computationally designed antiviral for influenza1R41AI122431-01FULLER, DEBORAH H.KODAY, MERIKA TREANTSVIRVIO, INC., WA$209,358ZRG1
2016Orally Bioavailable Gadolinium Chelators for Preventing and Ameliorating Toxicity Due to MRI Contrast Agents1R41CA203571-01JAY, MICHAELCAPTURE PHARMACEUTICALS, INC, NC$205,593ZRG1
2016Enabling Nanomembrane-Based Biomolecule and Nanoparticle Separations1R41GM116190-01A1MCGRATH, JAMES LSIMPORE, INC., NY$198,938ZRG1
2016Computerizing NIAAA's Best Practices for Youth Screening and Brief Intervention1R41AA024354-01A1MITCHELL, SHANNON GWINCOG ANALYTICS, LLC, MD$198,521ZRG1
2016development of immunodeficient rabbit models1R41AI122510-01XU, JIECELETRIX, LLC, VA$186,180ZRG1
2016Novel immunotherapy strategy for treatment of pancreatic cancer1R41CA195947-01A1MUKHERJEE, PINKUONCOTAB, INC, NC$182,461ZRG1
2016Treating collagen-induced arthritis (CIA) with immunoregulatory nanoparticles1R41AR068161-01A1MOSSER, DAVID MLEUKOSIGHT, INC., MD$179,502ZRG1
2016ARCHER - An Extremely Fast Medical Radiation Dose Computing Software1R42EB019265-01A1XU, XIE GEORGEVIRTUAL PHANTOMS, INC., NY$165,220ZRG1
2016Advanced Cannula Development for Coronary Sinus Access1R41HL129754-01A1SPOTNITZ, HENRY MICHAELSTRATEGIC PACING SYSTEMS, LLC, NJ$158,680ZRG1
2016Development of Alkontrol herbal for Treating Alcohol Abuse1R42AA022577-01A1 · under PA-13-235LI, HAIXIALUKAS, SCOTT ENATURAL PHARMACIA INTERNATIONAL, INC., MA$154,747ZRG1
2016Mobile Intervention Kit to Increase HIV/HCV Testing and Overdose Prevention Training1R41DA041246-01ARONSON, IAN DAVIDDIGITAL HEALTH EMPOWERMENT, INC., NY$152,762ZRG1
2016Clinical real-time resting state fMRI1R41NS090691-01A1POSSE, STEFANNEURINSIGHT, LLC, NM$150,000ZRG1
2016Bone targeted antimicrobials for biofilm-mediated osteolytic infection treatment1R41DE025789-01EBETINO, FRANK H.SEDGHIZADEH, PARISH PAYMONBIOVINC, LLC, CA$149,963ZRG1
2016Optimization of small molecule triazine antituberculars for in vivo efficacy1R41AI122434-01EKINS, SEANCOLLABORATIONS PHARMACEUTICALS, INC., NC$149,388ZRG1
2016Single-Molecule Analyte Detection by Molecular Motor-driven Nanodevices1R41GM115039-01FRASCH, WAYNE DATTOMETRICS, LLC, AZ$149,265ZRG1
2015Novel commensal polysaccharide treats multiple sclerosis through Treg modulation2R42AI110170-02KASPER, LLOYD HSYMBIOTIX BIOTHERAPIES, INC., MA$2,264,726ZRG1
2015Therapeutic Vaccine Targeting CMV Antigens in Glioblastoma2R42CA153845-02SAMPSON, JOHN H.ANNIAS IMMUNOTHERAPEUTICS, INC., CA$1,227,385ZRG1
2015Clinical Translation of an Anti-Metastatic Antibody for Breast Cancer Therapy2R42CA176951-02A1RITTENHOUSE-OLSON, KATE WFOR-ROBIN, NY$973,366ZRG1
2015Nonlinear Computation Tool to Chart Trajectories of Bipolar Disorder2R42MH091997-03A1BOWDEN, CHARLES LEEPRIESMEYER, RICHARDBIOMEDICAL DEVELOPMENT CORPORATION, KY$869,569ZRG1
2015Live-Cell Fluorescence Lifetime FRET Assays for HTS2R42DA037622-03GILLISPIE, GREGORY DAVIDFLUORESCENCE INNOVATIONS, INC., MN$860,487ZRG1
2015Stroke Treatment by Chemically-induced Hypothermia2R42NS073378-03A1DIX, THOMAS A.YU, SHAN P.JT PHARMACEUTICALS, INC., SC$793,793ZRG1
2015Computer-aided detection of focal cortical dysplasias2R44NS083101-02A1FISCHL, BRUCESCHMANSKY, NICHOLAS JOHNCORTICOMETRICS, LLC, MA$750,677ZRG1
2015Development of Novel Compounds for Treatment of Heart Arrhythmias in CPVT2R42HL114206-02ABRAMSON, JONATHAN JELEX BIOTECH, LLC, OR$750,385ZRG1
2015Phase IIB: Portable Device for Telecare Monitoring of Elderly People2R42AG032748-04GWIN, JOSEPH TMOHLER, MARTHA JANENAJAFI, BIJANBIOSENSICS, LLC, MA$749,999ZRG1
2015Calibrated Methods for Quantitative PET/CT Imaging Phase II2R42CA167907-02ENQUOBAHRIE, ANDINET ASMAMAWKINAHAN, PAUL E.KITWARE, INC., NY$740,435ZRG1
2015Microfluidic Processing of Leukocytes for Molecular Diagnostic Testing2R42CA174121-02CIVIN, CURT ISTURM, JAMES CGPB SCIENTIFIC, INC., VA$739,526ZRG1
2015Evidenced-based Firefighter Worksite Health and Safety Intervention2R42TR000357-02 · under PA-13-235ELLIOT, DIANE LOUISEGOLDBERG, LINNODYSSEY SCIENCE INNOVATIONS, LLC, OR$714,294ZRG1
2015Remote Brief Intervention and Referral to Treatment Service for Alcohol (R-BIRT)2R42AA022035-03BOUDREAUX, EDWIN DPOLARIS HEALTH DIRECTIONS, INC., PA$693,416ZRG1
2015Lentiviral Vector for the treatment of Fanconi Anemia2R42HL099150-02A1GOEBEL, WILLIAM SCOTTRIMEDION, INC., CA$690,143ZRG1
2015Polaris Oncology Survivor Transition (POST) System2R42CA174048-03O'HEA, ERIN LEEPOLARIS HEALTH DIRECTIONS, INC., PA$684,311ZRG1
2015Multimodality Image-Based Assessment System for Traumatic Brain Injury2R44NS081792-03A1AYLWARD, STEPHEN RNIETHAMMER, MARCVAN HORN, JOHN DARRELLKITWARE, INC., NY$635,667ZRG1
2015Using game mechanics to improve outcomes among stem cell transplant survivors2R42CA168107-02ASKINS, MARTHA ANNMCLAUGHLIN, JEFFERYPETERSON, SUSAN KZHANG, DONGSONGRADIANT CREATIVE GROUP, LLC, TX$616,412ZRG1
2015Development of a novel method for inhibiting diabetic retinopathy2R42EY021943-02A1CLEMMONS, DAVID RCMP TARNHELM PARTNERS, LLC, NC$583,208ZRG1
2015Improving Outcomes for Mechanically Ventilated Patients with the Digital EZ Board2R42NR014087-02HAPP, MARY EVIDATAK, LLC, MI$579,646ZRG1
2015A crosslinked cartilage-derived matrix for cartilage tissue engineering2R44AR061916-02ESTES, BRADLEY TCYTEX THERAPEUTICS INC., NC$570,289ZRG1
2015Neuroimaging tools for presurgical brain mapping2R42CA173976-02DEYOE, EDGAR APILLAI, JAY JPRISM CLINICAL IMAGING INC., WI$552,991ZRG1
2015IMPROVING THE TREATMENT OF CONTAMINATED AQUIFERS BYDEVELOPING DIRECT-PUSH OXIDANT CANDLES WITH PNEUMATIC CIRCULATORS2R42ES022530-02CHRISTENSON, MARKAIRLIFT ENVIRONMENTAL, LLC, NE$540,036ZRG1
2015A Protective Tetravalent Vaccine Candidate for Dengue Fever Virus1R41AI115906-01JOHNSTON, ROBERT E.ALTRAVAX, INC., CA$532,838ZRG1
2015Design, Development, and Evaluation of an Interactive Tactile Graphics Printer for the Blind and VisuallyImpaired2R42TR000376-02A1ROSEN, MICHAEL J.EASY, LLC, VT$508,209ZRG1
2015A Force-controlled Probe Based Platform for Single-Cell Biomolecular Delivery2R44GM101833-02 · under PA-13-235YANG, RUIGUOINFINITESIMAL, LLC, IL$499,999ZRG1
2015Enhanced multiphoton microscopy through spatial light modulation2R42MH102201-02HOY, CHRISTOPHER LUKBOULDER NONLINEAR SYSTEMS, INC., CO$496,726ZRG1
2015AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P2R42GM100657-02 · under PA-13-235TAYLOR, LYNNE SANASYS INSTRUMENTS CORPORATION, CA$495,193ZRG1
2015Protein Sequencing Tools for Biological Therapeutics2R42GM103362-03FENYO, DAVIDPROTEIN METRICS, LLC, CA$494,418ZRG1
2015IMMEDIATE FIT USING INNOVATIVE TECHNOLOGY TRANSTIBIAL PROSTHESIS2R42AG050430-04DILLINGHAM, TIMOTHY RIFIT PROSTHETICS, LLC, WI$474,565MRS
2015APPSPIRE: expanding the reach of an innovative tobacco control program for youth2R42DA035012-02MCLAUGHLIN, JEFFERYPROKHOROV, ALEXANDER VRADIANT CREATIVE GROUP, LLC, TX$446,282ZRG1
2015Development of novel compounds for the treatment of atrial fibrillation1R41HL129570-01WEHRENS, XANDER H.T.ELEX BIOTECH, LLC, OR$427,638ZRG1
2015ASTROCYTE ACTIVATION BY SMALL MOLECULE P2Y1 AGONISTS FOR TREATMENT OF TBI1R41NS093756-01LECHLEITER, JAMES DASTROCYTE PHARMACEUTICALS, INC., MA$420,239ZRG1
2015RAP as a novel therapeutic to promote remyelination after MS demyelinating event1R43NS092182-01A1GAULTIER, ALBAN PSTILES, TRAVIS LEENOVORON BIOSCIENCE, INC., CA$353,106ZRG1
2015Selective inhibitors of Heme Transporters as Antiparasitic Agents1R41AI113998-01A1HAMZA, IQBALRAKTA THERAPEUTICS, INC., MD$350,126ZRG1
2015Rational design of small interfering RNA for genome-wide target knockdown1R41HG008567-01A1LIU, WEIJUNWANG, XIAOWEINAWGEN, LLC, IL$347,147ZRG1
2015HLS13-13 Albumin nanoparticle based technology to treat ARDS1R41HL126456-01MALIK, ASRAR B.CELL BIOLOGICS, INC., IL$344,039ZRG1
2015Development of a Broad Spectrum Antiviral for Ebola and Marburg viral Infections1R41AI115897-01DAVEY, ROBERT AOMM SCIENTIFIC, INC., TX$328,211ZRG1
2015A novel drug detection assay using fluorescent biosensor technology1R41GM110813-01A1MELCHIOR, DONALD LEEGLSYNTHESIS, INC., MA$320,466ZRG1
2015Targeting C/EBP-beta Phosphorylation for the Treatment of Lung Fibrosis1R41HL127919-01BUCK, MARTINACHOJKIER, MARIOXFIBRA, INC., CA$316,111ZRG1
2015DEVELOPMENT OF SMALL MOLECULE THERAPEUTICS AGAINST RNA VIRUSES1R41AI113952-01A1HARTY, RONALD NFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$300,000ZRG1
2015Developing therapeutic inhibitors of CIB1 for breast cancer1R41CA200189-01FRYE, STEPHEN VERNONPARISE, LESLIEREVERIS THERAPEUTICS, LLC, NC$300,000ZRG1
2015A Low-Cost Portable Multiplex Serum Molecular Test for HBV and HCV Detection1R41AI120445-01SHIH, WAN Y.LENIMA FIELD DIAGNOSTICS, LLC, PA$300,000ZRG1
2015Pre-IND Study of Pz-1, a dual pan-RET/VEGFR2 inhibitor for the Treatment of RET-driven Disease1R41CA195826-01FRETT, BRENDAN ANDREWLI, HONG YUSYNACTIX PHARMACEUTICALS, INC., AZ$299,975ZRG1
2015GPCR antagonists as anti-Ebola virus entry inhibitors1R41AI120437-01RONG, LIJUNMICROBIOTIX, INC, MA$299,392ZRG1
2015RSK3 Anchoring Disruptor Therapy for Heart Failure1R41HL129524-01KAPILOFF, MICHAEL SETHANCHORED RSK3 INHIBITORS, LLC, CA$299,024ZRG1
2015Retargeting FDA Approved Anticancer Liposomal Drugs to Cancer Stem Cells1R41CA192689-01SZOKA, FRANCIS C.ZONEONE PHARMA, INC., CA$298,920ZRG1
2015Novel sigma-2 receptor modulators for the treatment of cognitive dysfunction1R41AG052249-01IZZO, NICHOLAS JOHNCOGNITION THERAPEUTICS, INC., PA$298,527ZRG1
2015Treatment of Acute Radiation Syndrome using PIF, a Natural Immune Modulator1R41AI120546-01PAIDAS, MICHAEL JOHNBIOINCEPT, LLC, OH$298,309ZRG1
2015Real-Time Oxygen Monitoring for Tissue Health: Peripheral Artery Disease Application1R42HL127933-01NICHOLS, SCOTTWISNIEWSKI, NATALIE ANNPROFUSA, INC., CA$296,345ZRG1
2015Distance Filtering System for Retinal Implants1R42EY025136-01A1DAGNELIE, GISLINADVANCED MEDICAL ELECTRONICS CORPORATION, MN$296,344ZRG1
2015Novel filovirus entry inhibitors based on a pseudo-symmetrical biphenyl core1R41AI118122-01RONG, LIJUNMICROBIOTIX, INC, MA$288,568ZRG1
2015Lipoprotein synthesis inhibitors for multi-drug resistant Gram-negative therapy1R41AI118037-01MAIRA-LITRAN, TOMASMICROBIOTIX, INC, MA$288,494ZRG1
2015Pre-IND study of PMT-254, a pan-FLT3 inhibitor for the treatment of FLT3 driven cancers.1R41CA199753-01LI, HONG YUSHAH, NEIL PPROMUTECH PHARMACEUTICALS, INC., AZ$285,792ZRG1
2015Infant Screening of Early Communication Risk: The CISS, Phase II2R42DC013506-02CRESS, CYNTHIA JPAUL H. BROOKES PUBLISHING COMPANY, INC., MD$280,968ZRG1
2015Mechanistic Studies of a Novel Small Molecule HIV Inhibitor1R41GM115250-01NAKAMURA, ROBERTADVANCED GENETIC SYSTEMS, INC., CA$277,424ADDT
2015Development of novel lung cancer therapeutics targeting the DNA damage response1R41CA195926-01PAWELCZAK, KATHERINETURCHI, JOHN J.NERX BIOSCIENCES, INC., IN$249,431ZRG1
2015Targeting CD137L to MC1R-Expressing Melanoma Cells and Tumors.1R41CA196026-01MCLAUGHLIN, MARK LMORSE, DAVID LPILON-THOMAS, SHARIMODULATION THERAPEUTICS, INC., WV$244,801ZRG1
2015Technology-Guided Opioid Cessation for Post-Operative Pain1R41DA039640-01CARROLL, IAN RICHARDDAVIS, MICHAEL SEANMEDICASAFE, INC., NY$243,321ZRG1
2015Electronic Optimization of Stem Cell Derived Human Cardiac Myocytes1R41HL127901-01A1BETT, GLENNA C LCYTOCYBERNETICS, INC., NY$241,933ZRG1
2015Urine Diagnostics for Aspergillosis1R41AI115866-01MARR, KIEREN A.PEARL DIAGNOSTICS, INC., MD$238,175ZRG1
2015Intranasal Sulfamidase Delivery to the Brain1R43NS089383-01A1GLASS, CHARLES ALEXANDERTEGA THERAPEUTICS, INC., CA$237,138ZRG1
2015Neurotrophic Agents for Treating Parkinson's Disaese1R41NS089140-01A1DEFREES, SHAWNSENEB BIOSCIENCES, INC., CT$233,804ZRG1
2015A Visual Assessment System for Retinal Function/Drug Discovery1R41EY025913-01CHEN, DONG FENGLUO, GANGXIE, XINMIN SIMONAFASCI, INC., CA$233,235ZRG1
2015S-Nitrosothiol-Based Rinse/Aerosol Solutions For Treatment/Prevention of Rhinosinusitis1R41AI120443-01HERSHENSON, MARC B.MEYERHOFF, MARK EQIN, YUNOTA LABORATORIES, LLC, MI$232,832ZRG1
2015Pre-clinical Development of a Vaccine for the Treatment of Heroin Addiction1R42DA040422-01FUJII, GARYMOLECULAR EXPRESS, INC., CA$225,033ZRG1
2015INTELLIGENT MOUTHGUARD FOR MEASURING HEAD IMPACTS IN YOUTH ATHLETES1R41HD079158-01A1BARTSCH, ADAM JESSESPORTSGUARD LABORATORIES, INC., OH$225,000ZRG1
2015Small Molecules To Inhibit PCSK9-LDLR1R41HL126346-01BURGESS, KEVINSMALL MOLECULE PPI MIMICS, LLC, TX$225,000ZRG1
2015Axonal Transport HTS Platform for Neurodegeneration Drug Discovery1R41NS090693-01BEEBE, DAVID JLOWERY, ROBERT GBELLBROOK LABS, LLC, WI$225,000ZRG1
2015Novel adjuvant therapy for triple negative breast cancer1R41CA183399-01A1GONZALEZ-PEREZ, RUBEN RENEJYANT, INC., GA$225,000ZRG1
2015A Novel Approach to Purifying iPSC Derived Cell Cultures1R41GM114935-01TENENBAUM, SCOTT AHOCUSLOCUS, INC., NY$225,000ZRG1
2015Contraceptive testing for semen availability in male monkeys1R41HD084077-01ORAND, MICHAEL GENEEPPIN PHARMA, INC., NC$225,000ZRG1
2015Cloud quantitative imaging for whole-body tumor burden in neurofibromatoses1R41CA192600-01A1CAI, WENLIWU, YINIQ MEDICAL IMAGING, LLC, MA$225,000ZRG1
2015A Tool for Research on Emotion in Naturally Occurring Speech1R41LM012177-01CRANGLE, COLLEEN ELIZABETHLONGINO, HELEN ECONVERSPEECH, LLC, CA$225,000ZRG1
2015mTOR Substrate Phosphorylation: A New Bioassay for Therapeutics1R41NS093970-01CRINO, PETER BCOGNIZANCE BIOMARKERS, LLC, PA$225,000ZRG1
2015sxRNA-based Antiviral Approach targeting Epstein-Barr virus1R41AI115834-01A1BHADURI-MCINTOSH, SUMITAHOCUSLOCUS, INC., NY$225,000ZRG1
2015Effectiveness of VBP15, a dissociative steroidal analogue, on inflammation in a mouse model of arthritis1R41AR068816-01DAMSKER, JESSEREVERAGEN BIOPHARMA, INC., MD$225,000ZRG1
2015Novel piperazine tethered thiazole compounds as antimalarials1R41AI120351-01MICHAELS, HEATHER ANNSMART BIOMOLECULES, INC., FL$225,000ZRG1
2015Development of PAR2 Pepducins for the Treatment of Atopic Dermatitis1R42AR067617-01A1KULIOPULOS, ATHANOASIS PHARMACEUTICALS, MA$225,000ZRG1
2015Mapping electrogram morphology recurrence for atrial fibrillation ablation1R41HL127907-01A1NG, JASONGOLD T-TECH, INC., FL$225,000ZRG1
2015A Structural Brain MRI Dementia Forecast Tool1R41AG052246-01SABUNCU, MERT RORYSCHMANSKY, NICHOLAS JOHNCORTICOMETRICS, LLC, MA$225,000ZRG1
2015Biological treatment of bacterial keratitis1R41EY024475-01A1BRANDT, CURTIS RFILUTOWICZ, MARCIN SMOSER, MICHAEL JAMESAMEBAGONE, INC., WI$224,999ZRG1
2015New Class of Bright, Sharp, Tunable Red/Far-Red Fluorophores for Flow Cytometry1R41EB020470-01PITNER, JAMES BRUCENIRVANA SCIENCES, INC., NC$224,999ZRG1
2015Optimization of an integrin enhancing molecule for the treatment of Duchenne muscular dystrophy1R41AR067019-01A1BURKIN, DEAN J.STRYKAGEN CORPORATION, NV$224,999ZRG1
2015PDE4B Inhibitors for Treating Brain Injury1R41NS090666-01A1GURNEY, MARK ETETRA DISCOVERY PARTNERS, INC., MI$224,999ZRG1
2015Improving the therapeutic efficacy of a lead vaccine against plague using a novel adjuvant system1R41AI120353-01BOWEN, WILLIAM SEANLAWRENZ, MATTHEW BSHIRWAN, HAVALFASCURE THERAPEUTICS, LLC, KY$224,999ZRG1
2015AFARI: A Stylized Adaptive Mobility and Fitness Device for Outdoor Movement1R41AG052223-01A1BEAUMONT, RYAN MICHAELCACCESE, VINCENTRM BEAUMONT CORPORATION, ME$224,999MRS
2015Measuring Bladder Permeability with MRI using a Novel Contrast Agent Formulation1R41DK108397-01KAUFMAN, JONATHAN HLIPELLA PHARMACEUTICALS, INC., PA$224,999ZRG1
2015Smartphone Technology for Parents and Teens: Improving Vaccination Uptake1R41HD082901-01A1WOODALL, W GILLKLEIN BUENDEL, INC., CO$224,998ZRG1
2015Speech Enhancement Based on Auditory Coding of Voiced Signals1R41DC013916-01A1CARNEY, LAUREL H.OMNISPEECH, LLC, MD$224,997ZRG1
2015Restimulating memory T cell responses in elderly by a novel, live influenza vaccine1R41AI120269-01BILSEL, PAMUKIWASAKI, AKIKOFLUGEN, INC., WI$224,997ZRG1
2015Enhancing Care of the Aged and Dying in Prisons1R41AG049570-01PENROD, JANICE LKLEIN BUENDEL, INC., CO$224,986ZRG1
2015Directed Antifungal Therapy for HIV-associated Cryptococcal Meningitis1R41AI120751-01LAD, SHIVANAND PMCCABE, AARON RICHARDMINNETRONIX, INC., MN$224,976ZRG1
2015Development of Therapeutics to Treat Candida albicans Biofilm Infections1R41AI112038-01A1NOBILE, CLARISSA JANEBIOSYNESIS, INC., CA$224,956ZRG1
2015New Assays for Expression Profiling of MicroRNAs1R41HG008247-01A1LIU, WEIJUNWANG, XIAOWEINAWGEN, LLC, IL$224,951ZRG1
2015Delivery of peptides for inducing voiding associated with neurological retention1R41NS092178-01MARSON, LESLEYDIGNIFY THERAPEUTICS, LLC, NC$224,946ZRG1
2015Therapeutic Antibodies for Biofilm Infections1R41AI120425-01KAUVAR, LAWRENCE MICHAELTRELLIS BIOSCIENCE, INC., CA$224,946ZRG1
2015Knee-Biofeedback Rehabilitation Interface for Game-based Home Therapy (KneeBRIGHT)1R41AR067562-01A1KREPKOVICH, EILEEN T.BARRON ASSOCIATES, INC., VA$224,925ZRG1
2015Strength and BALance (SABAL) Virtual Trainer1R41AG046958-01A1ADAMS, RICHARD J.BARRON ASSOCIATES, INC., VA$224,918ZRG1
2015Development of a Novel Therapeutic Approach for Cryptococcal Meningitis1R41AI120304-01LAD, SHIVANAND PMCCABE, AARON RICHARDMINNETRONIX, INC., MN$224,917ZRG1
2015Preclinical and neuroimmunologic study of RTL1000 for methamphetamine addiction1R41DA039632-01HUCKANS, MARILYNLOFTIS, JENNIFER MVIROGENOMICS BIODEVELOPMENT, INC., OR$224,886ZRG1
2015Novel Activin A Antagonists for Treatment of Osteoporosis1R41AR068804-01MARTINEZ HACKERT, ERIK MATTHIASMESSMER, BRADLEY TABREOS BIOSCIENCES, INC., CA$224,811ZRG1
2015Developing a Diagnostic Blood Test for Sarcoidosis1R41HL129728-01MOLLER, DAVID ROBERTSARCOIDOSIS DIAGNOSTIC TESTING, LLC, NJ$224,780ZRG1
2015Lactoferrin Modulation of Granuloma Pathology1R41AI117990-01ACTOR, JEFFREY KKRUZEL, MARIAN LPHARMAREVIEW CORPORATION, TX$224,725ZRG1
2015Interactive technology for media literacy drug prevention in community groups1R41DA039595-01GREENE, KATHRYN LHECHT, MICHAELREAL PREVENTION, LLC, NJ$224,630ZRG1
2015Portable Multimode Persufflation/Perfusion System for Extended Hypothermic Kidney Preservation1R41DK108620-01PAPAS, KLEARCHOS KTEMPELMAN, LINDA AGINER, INC., MA$224,587ZRG1
2015Development and testing of a behavioral activation mobile therapy for elevated depressive symptoms1R41MH108219-01FELTON, JULIA WMOUNTAINPASS TECHNOLOGY, LLC, MD$224,573ZRG1
2015High Frequency Acceleration to Restore Alveolar Bone1R43DE025518-01WAY, BRYCEPROPEL ORTHODONTICS, LLC, NY$224,139ZRG1
2015BlueBox - a complete code blue data recorder1R41GM113463-01A1CHANG, RUEY-KANGNEOVATIVE, INC., CA$223,921ZRG1
2015Blood-based diagnostics for Alzheimer's Disease1R42AG049562-01SOTO, CLAUDIOVOLLRATH, BENAMPRION, INC., CA$223,574ZRG1
2015Continuous measurement of cell growth as an optimal tool in drug toxicity testing1R41TR001196-01COOK, DANIEL LENTOX SCIENCES, LLC, WA$223,503ZRG1
2015Identification of patients with diabetes at high risk for treatment failure1R41DK105612-01TURCHIN, ALEXANDERLP INFORMATION TECHNOLOGY, MA$223,336ZRG1
2015Validation and Cryopreservation of Ligament Engineered from Human Bone Marrow1R41AR066412-01A1ARRUDA, ELLEN MLARKIN, LISA MSTEL TECHNOLOGIES, LLC, MI$222,922ZRG1
2015Semi-Automated Processing of Interconnected Dyads Using Entity Resolution (SPIDER)1R43MH106361-01A1HOPKINS, CHRISTOPHER M.YOUNG, APRIL MARIECHARLES RIVER ANALYTICS, INC., MA$222,566ZRG1
2015Use of EF2K inhibitors to inhibit tumor growth and sensitize cancer cells to existing chemotherapy treatment1R41CA195923-01RYAZANOV, ALEXEY G.LONGEVICA PHARMACEUTICALS, INC., NJ$221,987ZRG1
2015Lowering the Cost of Imaging for Retinal Microvasculature in Diabetic Patients1R41EY026105-01ELSNER, ANN EAEON IMAGING, LLC, IN$221,519ZRG1
2015Engineering a phosphotyrosyl-tRNA Synthetase1R41GM113301-01WEINER, MICHAEL PAXIOMX, INC., CT$220,323ZRG1
2015Ultra-Sensitive Diagnosis of AIDS-Related Tuberculosis1R41AI118851-01CANGELOSI, GERARD AATTODX, INC., WA$220,230ZRG1
2015MRI brain morphometry for computer-aided detection of neurological disorders1R44NS089090-01A1FISCHL, BRUCESCHMANSKY, NICHOLAS JOHNCORTICOMETRICS, LLC, MA$218,641ZRG1
2015Synthetic lubricin biomaterial for osteoarthritis1R41AR068183-01PUTNAM, DAVID AARTICULATE BIOMEDICAL, LLC, NY$217,947ZRG1
2015Discovery of Oligodendrocyte Stimulators1R41NS095475-01RIVKEES, SCOTT A.MEDOSOME BIOTEC, LLC, FL$217,801ZRG1
2015Clonotyping Technology for Prediction of Antibiotic Resistance1R41AI116114-01APRIKIAN, PAVELSOKURENKO, EVGENI VENIAMINOVICIDGENOMICS, INC., WA$214,436ZRG1
2015Diagnosing aggressive prostate cancer by spectroscopic photoacoustic tomography1R41CA192645-01CHENG, JI-XINVIBRONIX, INC., IN$212,978ZRG1
2015A biochemical companion diagnostic platform to measure kinase inhibitor pharmacodynamics in leukemia1R41CA186505-01A1HOBAUGH, MARKPARKER, LAURIE L.MICROFLUIDIC INNOVATIONS, LLC, IN$211,754ZRG1
2015StrikeVEMP: Automated Portable Bone-Conducted Force Stimuli for Recording Acceleration-Produced coVEMPs1R41DC014874-01WACKYM, P. ASHLEYEAR AND SKULL BASE CENTER, PC, OR$211,604ZRG1
2015Maximal MYC control using dual PI-3K/BRD4 (kinase/epigenetic) inhibitors1R41CA192656-01DURDEN, DONALDSIGNALRX PHARMACEUTICALS, INC., GA$209,001ZRG1
2015Asthmagram: objective assessment of asthma symptoms in children1R41HL127868-01CHANG, RUEY-KANGNEOVATIVE, INC., CA$207,102ZRG1
2015Evaluation of TRB-N0224, a Proprietary Chemically Modified Curcumin, for the Treatment of Periodontal Disease in a LPS-Induced Rat Model1R41DE024946-01GOLUB, LORNE MGU, YINGTRAVERSE BIOSCIENCES, INC., NY$205,709ZRG1
2015Family Supportive Supervisor Training and Workplace Assessment Tool1R41AG050347-01KOSSEK, ELLEN ERNSTWORK LIFE HELP, INC., MI$201,333ZRG1
2015Developing efficient and safe cell-permeable reprogramming peptides for generation of iPS cells.1R41GM113529-01ZHU, YONGVIVOSCRIPT, INC., CA$200,082ZRG1
2015Peptide Based Therapy for Lung Fibrosis1R42HL127802-01FEGHALI-BOSTWICK, CAROL A.PADGETT, HAL SNOVICI BIOTECH, LLC, CA$199,999ZRG1
2015IRE1 alpha inhibitors for type 2 diabetes1R41DK108377-01BACKES, BRADLEY JOPTIKIRA, LLC, OH$199,611ZRG1
2015Shape Memory Polymer Foam Vascular Occlusion Device for the Treatment of Chronic Venous Insufficiency1R43EB022016-01A1LANDSMAN, TODDSHAPE MEMORY MEDICAL INC., CA$199,591ZRG1
2015Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model1R42AR066439-01A1GUILAK, FARSHIDCYTEX THERAPEUTICS INC., NC$190,720ZRG1
2015TruEnamel: A dental product that treats, protects, desensitizes and whitens teeth1R41DE024011-01A1CLARKSON, BRIAN HTRUENAMEL, LLC, MI$188,406ZRG1

Showing the 200 most recent of 387 awards.

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