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NIH funding notice PA-15-270

PHS 2015-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])

Closed on April 5, 2016.

Posted
June 4, 2015
Close date
April 5, 2016
Activity codes
R41, R42
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, ORIP

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-14-072 PHS 2014-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]
  2. 2 steps back: PA-13-235 Reissue PHS 2013-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  3. 3 steps back: PA-13-089 PHS 2013-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  4. 4 steps back: PA-12-089 PHS 2012-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  5. 5 steps back: PA-11-097 PHS 2011-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  6. 6 steps back: PA-10-051 PHS 2010-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  7. 7 steps back: PA-09-081 PHS 2009-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])

Replaced by PA-16-303.

Who won it before

559 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $176,882,049 in first-year total cost, median $224,999.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ETTN-M (11)]45
  2. Special Emphasis Panel[ZRG1 SBIB-T (10)]42
  3. Special Emphasis Panel[ZRG1 OTC-T (10)]36
  4. Special Emphasis Panel[ZRG1 RPHB-C (10)]24
  5. Special Emphasis Panel[ZRG1 ETTN-G (12)]23

Most frequent institutions

  1. FOX CHASE CHEMICAL DIVERSITY CENTER, INC6
  2. CORTICOMETRICS, LLC5
  3. MEDOSOME BIOTEC, LLC5
  4. MICROBIOTIX, INC5
  5. BARRON ASSOCIATES, INC.4
Competing awards under PA-15-270 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2017Peripheral FAAH as a target for novel analgesics2R42DA033683-02A1 · under PA-14-072PIOMELLI, DANIELEANTEANA THERAPEUTICS, INC., CA$1,100,244ZRG1
2017Validation of Novel Therapeutic Approach for Cryptococcal Meningitis2R42AI120304-02LAD, SHIVANAND PMCCABE, AARON RICHARDMINNETRONIX, INC., MN$1,000,000ZRG1
2017Design and Development of Immunotolerant S. aureus Biotherapies2R42AI118133-02BAILEY-KELLOGG, CHRISGRISWOLD, KARL ELYTICON, LLC, NH$868,526ZRG1
2017Development of user-friendly fluorescence based assays for marine toxins2R42ES023724-02A1MCCALL, JENNIFER RETTEWSEATOX RESEARCH, INC., NC$854,503ZRG1
2017Lactoferrin Modulation of Granuloma Pathology2R42AI117990-02ACTOR, JEFFREY KKRUZEL, MARIAN LPHARMAREVIEW CORPORATION, TX$815,321ZRG1
2017Clinical Translation of Augmented Reality Visualization for Laparoscopic Surgery2R42CA192504-02SHEKHAR, RAJIGI TECHNOLOGIES, INC., MD$774,136ZRG1
2017AutoRegister: A system for enhancing the accuracy of tumor change detection2R42CA183150-02VAN DER KOUWE, ANDRE JAN WILLEMWIGHTON, PAULCORTICOMETRICS, LLC, MA$750,000ZRG1
2017Development of PAR4 Pepducins as a Novel Antithrombotic Treatment1R41HL134517-01A1KULIOPULOS, ATHANOASIS PHARMACEUTICALS, MA$366,484ZRG1
2017Anti-CCL25 mAb to treat castration resistant prostate cancer1R41CA214080-01SINGH, SHAILESHJYANT, INC., GA$350,000ZRG1
2017Aminooxyacetic Acid Prodrugs for Colon Cancer Therapy1R41CA213463-01SZABO, CSABACBS THERAPEUTICS, INC., TX$300,000ZRG1
2017DEVELOPMENT OF A NOVEL ANTIVIRAL TO TREAT AND PREVENT ACYCLOVIR RESISTANCE IN HUMAN OCULAR HERPES KERATITIS1R41EY026849-01A1RICCIARDI, ROBERT PAULFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$299,999ZRG1
2017Infection Site Targeted Antitoxin Antibody (ISTAb) against Bacillus anthracis1R41AI122666-01A1ADHIKARI, RAJAN PHAKAMI, RAMIN M.NELSON, DANIEL C.INTEGRATED BIOTHERAPEUTICS, INC., MD$294,932ZRG1
2017Large Scale Preparation of Natural Glycans1R41GM122139-01SONG, XUEZHENGNATGLYCAN, LLC, GA$285,524ZRG1
2017Development of MTX-211 for the Treatment of KRAS Mutant Colorectal Cancer1R41CA213715-01LEOPOLD, JUDITH SWHITEHEAD, CHRISTOPHER EMILMEKANISTIC THERAPEUTICS, LLC, MI$275,000ZRG1
2017Online Practitioner Training in Behavioral Intervention in Autism: Skill Training Using an Interactive Simulated Child1R41MH116534-01A1SERNA, RICHARD WPRAXIS, INC., MA$250,387ZRG1
2017A novel anti-gonorrhea immunotherapeutic1R41AI129106-01RAM, SANJAYWYCOFF, KEITHPLANET BIOTECHNOLOGY, INC., CA$242,093ZRG1
2017Novel HDAC Inhibitors for Treatment of Hemoglobinopathies1R41HL136068-01PERRINE, SUSAN PARKWILLIAMS, ROBERT MICHAELCETYA THERAPEUTICS, INC., CO$241,742ZRG1
2017Developing a new therapeutic agent for retinal ciliopathies1R41EY027667-01KATSANIS, NICHOLASRESCINDO THERAPEUTICS, INC., NC$238,837ZRG1
2017Novel Small Molecule Macrophage Inhibitors for the Treatment of Retinal Diseases1R41EY027219-01COUSINS, SCOTT WILLIAMEYEDESIS BIOSCIENCES, LLC, NC$225,030ZRG1
2017Testing and Commercialization of a Superior Device to Maintain Perioperative Normothermia In Anesthetized Patients.1R41GM119871-01A1DILLER, KENNETH R.MERCURY BIOMED, LLC, OH$225,000ZRG1
2017An integrative multi-phenotype pipeline for drug evaluation, pharmacogenomics, and attribute prediction1R41TR001908-01JAEGER, PHILIPPPHENVOGEN, LLC, CA$224,991ZRG1
2017Soluble E-NTPDase for sepsis1R41GM120838-01A1HASKO, GEORGEPURINE PHARMACEUTICALS, INC., NJ$224,871ZRG1
2017Bioimpedance-based Intracranial Mapping for Monitoring Evolving TBI1R41NS100313-01HALTER, RYAN JOSEPHRYTEK MEDICAL, INC., NH$224,609ZRG1
2017Targeting Synaptotagmin-2 to Prevent Airway Mucus Obstruction1R41HL136057-01DICKEY, BURTON FVARADHACHARY, ATULEXOTECT, LLC, TX$224,576ZRG1
2017Tools for site-specific antibody immobilization for immunoassays1R41EB023750-01TSOURKAS, ANDREWALPHATHERA, INC., PA$224,556ZRG1
2017Microparticulate mucosal vaccine for triple-negative breast cancer1R41CA206652-01A1CHIRIVA-INTERNATI, MAURIZIOMIRANDOLA, LEONARDOKIROMIC, INC., TX$224,522ZRG1
2017Automated Electrophysiology Assessment of Drug-induced Cardiotoxicity Based on Parallel, Noninvasive Nanoelectrode Array1R41EB022439-01A1JIANG, XINCYION TECHNOLOGIES, LLC, CA$223,028ZRG1
2017Application of PPODA-QT for embolization of aneurysms1R41NS097069-01A1BECKER, TIMANEUVAS TECHNOLOGIES, INC., AZ$220,109ZRG1
2017AML-MutationCounter, a tool to detect residual and recurrent leukemia1R41CA213690-01KAUFMANN, WILLIAM K.ASYSTBIO LABORATORIES, LLC, NC$220,087ZRG1
2017Therapeutic Mabs for Chronic Kidney Disease1R41DK112426-01LUKACS, NICHOLAS WOPSIDIO, LLC, PA$217,446ZRG1
2017A Preclinical Trial of Therapeutic Angiogenesis Plus Angioplasty and Stenting for Renal Vascular Disease1R41DK109737-01A1BIDWELL, GENE LEFLORELEFLORE TECHNOLOGIES, LLC, MS$216,429ZRG1
2017Novel sanitizer against viral infections with long-lasting effect1R41AI124738-01A1HSU, STEPHENCAMELLIX, LLC, GA$192,601ZRG1
2017The Patient Centered Postpartum Contraception ToolKit (PC2)1R41HD090825-01GILLIAM, MELISSASPARROW, ASHLYNRESILIENT GAMES STUDIO, LLC, IL$149,916ZRG1
2017eHealth Mobile Technology Connecting Young Adults to Routine Engagement (eMCARE), a theoretically and empirically driven mobile intervention to engage young adults in healthcare.1R41HD090813-01SHAABAN, SAMINURELM E-BUSINESS SOFTWARE, PA$149,439ZRG1
2017Designing and Evaluating Outcome Assessment Software for Youth with Developmental Disabilities: The Pediatric Evaluation of Disability Inventory- Patient Reported Outcome (PEDI-PRO)1R41HD090772-01DAVIES, DANIEL KKRAMER, JESSICA MARVELLEABLELINK TECHNOLOGIES, INC., CO$132,454ZRG1
2016Therapeutics for inflammatory bowel disease from the microbiome2R42DK103361-02MAZMANIAN, SARKIS KSYMBIOTIX BIOTHERAPIES, INC., MA$1,973,386ZRG1
2016The Allogeneic Heart Stem Cell Trial in Hypoplastic Left Heart Syndrome Patients1UT2HL131226-01 · under PA-14-072RODRIGUEZ-BORLADO, LUISCAPRICOR, INC., CA$1,683,381ZRG1
2016New generation of catheters for treatment of atrial fibrillation2R42HL120511-02 · under PA-14-072SARVAZYAN, NARINENOCTURNAL PRODUCT DEVELOPMENT, LLC, NC$1,173,082ZRG1
2016Preclinical Testing of a Novel Flow Diverting Stent for Treating Intracranial Aneurysms2R42NS074576-03 · under PA-14-072KALLMES, DAVID FKEALEY, COLIN PATRICKNEUROSIGMA, INC., CA$1,072,694ZRG1
2016A Phase 2a clinical trial of ALK-001 in geographic atrophy2R44EY021988-02A1 · under PA-14-072SAAD, LEONIDEWASHINGTON, ILYASALKEUS PHARMACEUTICALS, INC., MA$1,054,287ZRG1
2016Developing Therapeutics That Target RAD51 To Treat Leukemia and Lymphoma2R42CA183197-02A1MILLS, KEVIN DCYTEIR THERAPEUTICS, INC., MA$1,038,983ZRG1
2016Small Molecule Inhibitors of HIV1 Nef Virulence Factor for Treatment of HIV_AIDS2R42GM112516-02SMITHGALL, THOMAS E.FOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$1,001,024ADDT
2016Clonotyping Technology for Prediction of Antibiotic Resistance2R42AI116114-02 · under PA-14-072KAWASAKI, GLENNOSTER, JEFFREYSOKURENKO, EVGENI VENIAMINOVICIDGENOMICS, INC., WA$999,967ZRG1
2016Rapid Immunodiagnosis of Drug-Resistant Bacterial Pathogens2R42AI108029-03GEISBERG, MARKSILVER LAKE RESEARCH CORPORATION, CA$994,558ZRG1
2016Humanized Monoclonal Antibody to Treat Acinetobacter Infections2R42AI106375-03ISLAM, KHALIDBIOLOGICAL ANTI-INFECTIVE MEDICINES, LLC, MD$982,415ZRG1
2016SMALL MOLECULE ANTAGONISTS OF PF4 FOR THE TREATMENT AND PREVENTION OF HIT2R42HL123126-02 · under PA-14-072SACHAIS, BRUCE SFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$980,000ZRG1
2016Delivery of peptides for inducing voiding associated with neurological retention2R42NS092178-02MARSON, LESLEYDIGNIFY THERAPEUTICS, LLC, NC$953,265ZRG1
2016Development of VLP vaccine for RSV2R42AI109926-02BLANCO, JORGE CSIGMOVIR BIOSYSTEMS, INC., MD$933,962ZRG1
2016Pre-Clinical Safety and Efficacy of TRB-N0224 for the Treatment of Periodontal Disease2R42DE024946-02GOLUB, LORNE MGU, YINGTRAVERSE BIOSCIENCES, INC., NY$888,810ZRG1
2016AcetaSTAT Rapid Assay for Acetaminophen Liver Injury2R42DK079387-06A1JAMES, LAURA PHILLIPSACETAMINOPHEN TOXICITY DIAGNOSTICS, LLC, AR$875,076ZRG1
2016Wireless sensor and telemedicine to screen for sleep apnea in elderly adults2R42MD008845-02ARNEDT, J. TODDZANSORS, LLC, VA$802,553ZRG1
2016Optimized lactoferrin for treatment of intracerebral hemorrhage2R42NS090650-02ARONOWSKI, JAROSLAWKRUZEL, MARIAN LPHARMAREVIEW CORPORATION, TX$776,623ZRG1
2016Mutation Enriched Targeted Re-Sequencing2R42CA180389-02A1 · under PA-14-072MAKRIGIORGOS, G. MIKEWU, GRANTTRANSGENOMIC, INC., NE$773,511ZRG1
2016Modulation of the Innate Immune Response by Fisetin Derivatives for the Treatment of AD2R42AI104034-03A1MAHER, PAMELA ANNEVIROGENICS, INC., CA$771,449ZRG1
2016Enhancing Care of the Aged and Dying in Prisons2R42AG049570-02LOEB, SUSAN JAYNEPENROD, JANICE LKLEIN BUENDEL, INC., CO$766,067ZRG1
2016A user-friendly scalable microfluidic platform for enhanced neuron-cell culture2R42MH097377-03A1TAYLOR, ANNE MARIONXONA MICROFLUIDICS, LLC, NC$763,929ZRG1
2016The CellRaft AIR System: Workflow Automation for Stem Cell Isolation and Recovery2R42GM106421-02 · under PA-14-072ALLBRITTON, NANCY L.CELL MICROSYSTEMS, INC., NC$748,655ZRG1
2016Simultaneous, Proportional and Independent sEMG-Based Hand-Wrist Prosthesis Control2R42HD076519-02CLANCY, EDWARD ALIBERATING TECHNOLOGIES, INC., MA$742,455ZRG1
2016New Class of Bright, Sharp, Tunable Near-Infrared Fluorophores for Flow Cytometry2R42AI112302-02PITNER, JAMES BRUCENIRVANA SCIENCES, INC., NC$738,015ZRG1
2016Memory Care Partner2R42AG044147-02A1 · under PA-14-072ANDERSEN, TROYFOSTER, NORMAN LOUISPROACTIVE MEMORY SERVICES, INC., UT$734,115ZRG1
2016Development and validation of therapy for mucopolysaccharidosis III2R42NS089061-02EKINS, SEANPHOENIX NEST, INC., NY$717,207ZRG1
2016Development of small near-infrared laser system capable of improving immune responses to vaccines (laser-based adjuvant)2R42AI114012-02 · under PA-14-072BEAN, DAVIDVERALASE, LLC, MA$696,264ZRG1
2016Automated Problem and Allergy Lists Enrichment Based on High Accuracy Information Extraction from the Electronic Health Record2R42CA180190-02A1MEYSTRE, STEPHANECLINACUITY,INC., SC$684,880ZRG1
2016Medical Sensor Applications of Tunnel Magnetoresistance (TMR)2R42DC012725-02A1KNUESEL, ROBERT JKORONIS BIOMEDICAL TECHNOLOGIES CORPORAT, MN$624,323ZRG1
2016Single Cell Analysis via Nanoscale Tip-Enhanced Laser Ablation Mass Spectrometry2R42GM106454-02 · under PA-14-072MURRAY, KERMIT KINGANASYS INSTRUMENTS CORPORATION, CA$597,820ZRG1
2016Newborn Infant Vision Test2R42EY022545-02A1KOPIDLANSKY, EDWARD GPRECISION VISION, INC., IL$587,619ZRG1
2016Identifying activators of interferon regulatory factors for neuroprotection.2R42NS095538-02STENZEL-POORE, MARY PNEURALEXO, LLC, OR$506,682ZRG1
2016Macromolecule Crystallization Screening Results Analysis2R42GM116283-02PUSEY, MARC LEEIXPRESSGENES, INC., AL$489,775ZRG1
2016In-Situ Gelling Protein Polymer Intravascular Embolic Agent for Hepatic Carcinoma2R42CA168123-02A1CHENEY, DARWIN LEROYGHANDEHARI, HAMIDTHERATARGET, UT$400,462ZRG1
2016A Novel Biologic for the Treatment of Hypogonadism1R41AG053124-01ATWOOD, CRAIG SJANGOBIO, LLC, WI$364,157ZRG1
20164-(Aminomethyl) benzamides as novel anti-Ebola agents1R41AI126971-01RONG, LIJUNCHICAGO BIOSOLUTIONS, INC., IL$363,601ZRG1
2016High-potency nitro antimicrobials for topical treatment of trichomoniasis1R41AI118089-01A1 · under PA-14-072ECKMANN, LARSPEYTON, DAVID HDESIGNMEDIX, INC., OR$353,902ZRG1
2016A microfluidic quality-control assay for stem-cell derived therapies1R41TR001203-01A1 · under PA-14-072NEUMANN, THOMASNORTIS, INC., WA$325,000ZRG1
2016Development of a small molecule activator of integrin cell adhesion to enhance therapeutic responses to checkpoint blockade in cancer1R41CA203456-01A1MARATHI, UPENDRAOVERWIJK, WILLEM WWOODSIDE, DARREN G7 HILLS PHARMA, LLC, TX$313,705ZRG1
2016T3SS needle protein inhibitors for the treatment of P. aeruginosa infection1R41AI122433-01 · under PA-14-072MECSAS, JOAN CMICROBIOTIX, INC, MA$302,983ZRG1
2016Combinatorial Inactivation of ERBB Receptors in Breast Cancer using Therapeutic Stapled Peptides1R41CA203353-01 · under PA-14-072SCHROEDER, JOYCE AARIZONA CANCER THERAPEUTICS, LLC, AZ$300,000ZRG1
2016Antibody targeting of ADAM8 for treatment of triple-negative breast cancer1R41CA200161-01A1 · under PA-14-072SONENSHEIN, GAIL E.ADECTO PHARMACEUTICALS, INC., MA$300,000ZRG1
2016Temozolomide Perillyl Alcohol Conjugate as Treatment for Recurrent Malignant Brain tumors1R41CA192419-01A1CHEN, THOMAS C.HOFMAN, FLORENCE MNEONC TECHNOLOGIES, INC., CA$300,000ZRG1
2016Therapeutic inhibition of P. aeruginosa nitrogen respiration in chronic infection1R41AI118120-01A1KAZMIERCZAK, BARBARA IL2 DIAGNOSTICS, LLC, CT$300,000ZRG1
2016Aminoglycosides with reduced ototoxicity1R41AI126874-01ARYA, DEV PRIYANUBAD, LLC, SC$300,000ZRG1
2016Simple, low cost assay for detection of HIV-1 antiretroviral resistance in resource-limited settings1R41AI124932-01A1STEVENSON, MARIODISCIDIUM BIOSCIENCES, LLC, FL$300,000ZRG1
2016Inhibitors of the viral nucleoprotein-polymerase co-factor interaction for human RSV and MPV therapy1R41AI127009-01MOIR, DONALD TMICROBIOTIX, INC, MA$300,000ZRG1
2016Therapy for drug resistant influenza strains by nucleic acid targeting of respiratory airways1R41AI124851-01A1JONES, CHARLES HOUSTONABCOMBI BIOSCIENCES, INC., NY$300,000ZRG1
2016Ultrasensitive Point-of-Care Diagnostics of Viral Biomarkers and Infectious Diseases1R41AI127055-01HENKEL, GREGORY WILLIAMYANIK, AHMET ALIARISAN THERAPEUTICS, INC., CA$300,000ZRG1
2016Ultrasensitive SERS Nano-Sensors for Pancreatic Cancer Diagnosis and Prognosis1R41CA213718-01JUNKER, WADE MKAUR, SUKHWINDERSANGUINE DIAGNOSTICS AND THERAPEUTICS, NE$300,000ZRG1
2016Highly specific ATR inhibitors for the targeted treatment of a broad spectrum of cancers1R41CA203436-01A1BROWN, ERIC JGILAD, ORENATRIN PHARMACEUTICALS, PA$299,998ZRG1
2016Optimization of a novel cancer immunotherapeutic antibody for human use1R41CA206688-01A1WU, JENNIFER DCANCURE, LLC, WA$299,994ZRG1
2016A universal vaccine for the prevention of meningococcal meningitis in Africa1R41AI124759-01A1MOE, GREGORY ROBERTOMVAX, INC., CA$299,970ZRG1
2016A Sparse-readout Quantitative PET scanner for breast cancer therapy optimization1R41CA213909-01HUNTER, WILLIAM COULIS JASONPET/X, LLC, WA$299,970ZRG1
2016Simvastatin nanomedicine in ARDS and sepsis1R41GM121153-01ROBERTS, SHAWN KENNYEUNOIA BIO TECH, LLC, PA$299,940ZRG1
2016Maximizing cancer synthetic lethality using dual PI-3K/PARP inhibitors1R41CA206859-01A1DURDEN, DONALDSIGNALRX PHARMACEUTICALS, INC., GA$299,738ZRG1
2016Precision, pulmonary disease evaluation and lung cancer detection using quantitative low-dose CT1R41CA206646-01SIEREN, JESSICA CVIDA DIAGNOSTICS, INC., IA$299,713ZRG1
2016Small molecule inhibitors targeting oncogenic drivers of hepatocellular carcinoma1R41CA195908-01A1 · under PA-14-072WAJAPEYEE, NARENDRAL2 DIAGNOSTICS, LLC, CT$298,959ZRG1
2016B7-H3-Targeted Contrast Agent for Ultrasonic Imaging of Breast Cancer1R41CA213544-01DAHL, JEREMYUNGER, EVAN CHARLESNUVOX PHARMA, LLC, AZ$298,820ZRG1
2016Pancreatic Ductal Adenocarcinoma Targeted Ultrasound Contrast Agent Development1R41CA203090-01 · under PA-14-072UNGER, EVAN CHARLESWILLMANN, JUERGEN KARLNUVOX PHARMA, LLC, AZ$297,786ZRG1
2016Mitochondrial TAT-DNA repair proteins for treatment of insulin resistance1R41DK109753-01WILSON, GLENNEXSCIEN CORPORATION, AL$296,128ZRG1
2016A small molecule integrin activator to enhance cord blood transplant1R41HL129612-01A1MARATHI, UPENDRAVANDERSLICE, PETER7 HILLS PHARMA, LLC, TX$295,931ZRG1
2016Novel antibacterial agents derived from natural products1R41AI118104-01A1 · under PA-14-072PRIESTLEY, NIGEL DPROMILIAD BIOPHARMA, INC., MT$295,729ZRG1
2016Optimization of the Production and Isolation of the Novel Antifungal Occidiofungin1R41AI122441-01A1SMITH, JAMES LEIFSANO CHEMICALS, INC, TX$295,381ZRG1
2016Monospecific monoclonal antibodies against human protein complexes on an interactome-wide scale.1R41CA210822-01LACAVA, JOHNCDI LABORATORIES, INC., PR$294,320ZRG1
2016Small Molecule Antibiotic Potentiators for Drug-Resistant Bacteria1R41AI115915-01A1 · under PA-14-072JUNG, DAVIDAGILE SCIENCES, INC., NC$294,309ZRG1
2016Proteolytic Imaging of Remodeling Myocardium1R42HL131280-01A1SPINALE, FRANCIS GMICRO VIDE, LLC, SC$294,131ZRG1
2016Development of Optimized AAV Serotype Vectors for Human Gene Therapy1R41AI122735-01 · under PA-14-072SRIVASTAVA, ARUNMEDOSOME BIOTEC, LLC, FL$294,094ZRG1
2016A Method to Increase Buprenorphine Treatment Capacity and Effectiveness1R42DA041941-01A1LISS, ROSALYNSHI, JULIACBT4CBT, LLC, FL$293,694ZRG1
2016Development of peptide inhibitors for neuroinflammation and neurodegeneration1R41AG053117-01SRINIVASAN, MYTHILYPROVAIDYA, INC., IN$284,145ZRG1
2016A Novel STAT3 Inhibitor Targeting its DNA-Binding Site for Drug Development1R41CA195777-01A1 · under PA-14-072LIU, JASMINE JINGYUANQRKANSWER, IN$279,838ZRG1
2016Novel SCD1 inhibitors for treatment of cancer1R41CA195946-01A1 · under PA-14-072COPLAND, JOHN A.HAZLEHURST, LORIMODULATION THERAPEUTICS, INC., WV$279,000ZRG1
2016HELical Biodegradable Photochemical(HELP)Stents for AVF Maturation1R41DK111332-01ROY-CHAUDHURY, PRABIRINOVASC, LLC, OH$275,529ZRG1
2016An epitope-focused nanoparticle vaccine for MRSA and biodefense1R41AI122594-01 · under PA-14-072OSCHERWITZ, JONWHITACRE, DAVID CVLP BIOTECH, INC., CA$273,748ZRG1
2016Digital Gene Expression Analysis by 3’ End Sequencing1R41HG008921-01 · under PA-14-072TIAN, BINTOLOUE, MASOUDBIOO SCIENTIFIC CORPORATION, TX$270,000ZRG1
2016Drug Activation of HSF1 for Prevention of Noise-Induced Hearing Loss1R41DC015411-01A1KOHRMAN, DAVID CSIPPOLA-THIELE, MARIA SIRPACHAPERONE THERAPEUTICS, INC., NC$269,999ZRG1
2016Product Development of Intensity Modulation for Bolus Electron Conformal Therapy1R41CA199838-01A1ERHART, KEVIN JAMESDECIMAL, INC., FL$261,141ZRG1
2016A chimeric protein for the selective expansion of regulatory T cells1R41AI125039-01PRABHAKAR, BELLUR SSAHANE BIOTECH, INC., IL$260,665ZRG1
2016Automated Object Contouring Methods & Software for Thoracic Radiotherapy Planning1R41CA199735-01A1UDUPA, JAYARAM KQUANTITATIVE RADIOLOGY SOLUTIONS, LLC, PA$254,097ZRG1
2016Effectiveness of VBP15, a dissociative steroidal analogue, on chronic inflammation in a mouse model of multiple sclerosis1R41AI122780-01A1DAMSKER, JESSEREVERAGEN BIOPHARMA, INC., MD$253,802ZRG1
2016A method for accurate and sensitive detection of HIV drug-resistant minority variants1R41AI122855-01A1WANG, GARY P.MEDOSOME BIOTEC, LLC, FL$253,244ZRG1
2016Targeted and Non-targeted Microbubbles for Pediatric Applications1R41HD089823-01KUTTY, SHELBYUNGER, EVAN CHARLESNUVOX PHARMA, LLC, AZ$243,164ZRG1
20164-Aminopiperidines as novel anti-influenza agents1R41AI127031-01RONG, LIJUNCHICAGO BIOSOLUTIONS, INC., IL$242,913ZRG1
2016Generation of antibodies to monitor Notch O-fucosylation in vivo1R41GM119879-01A1ORLANDO, RONGLYCOSCIENTIFIC, LLC, GA$242,306ZRG1
2016A brief iPad-based screening measure for HIV-associated neurocognitive disorders2R42MH099964-02A1MARCOTTE, THOMAS DSEVERSON, JOAN MDIGITAL ARTEFACTS, LLC, IA$240,880ZRG1
2016Nanoparticle Delivery System for Ewing Sarcoma Treatment1R41CA203457-01A1NAGY, JON OWENTRICHE, TIMOTHY J.NANOVALENT PHARMACEUTICALS, INC., MT$240,750ZRG1
2016Targeted Polymerized Shell Microbubbles to Image Surgical Adhesions1R41GM116530-01A1 · under PA-14-072NAGY, JON OWENWONG, JOYCE YNANOVALENT PHARMACEUTICALS, INC., MT$238,728ZRG1
2016Molecular Imaging of Early Stage of Liver Fibrosis by Novel Protein Agents1R41AA025863-01YANG, JENNY J.INLIGHTA BIOSCIENCES, LLC, GA$238,587ZRG1
2016Streamlining HTS Assay Development through Direct Selection of Structure-Switching Aptamers1R41GM121123-01HEEMSTRA, JENNIFER MARGARETLOWERY, ROBERT GBELLBROOK LABS, LLC, WI$234,936ZRG1
2016Biological super-resolution imaging using high-index microspheres for cancer research application1R41GM117844-01 · under PA-14-072CARABE-FERNANDEZ, ALEJANDRODARAFSHEH, ARASHLEE, DAEYEONSPHEREVIS, LLC, PA$233,419ZRG1
2016Optimizing Vaccines by Targeting Dendritic Cells with IFNa and IFNb Inducing Adjuvants1R41AI118522-01A1 · under PA-14-072DANLEY, DAVID LAWRENCEPARABON NANOLABS, INC., VA$230,000VACC
2016Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease1R41AI122403-01 · under PA-14-072AMAN, M JAVADLAI, JONATHAN R.INTEGRATED BIOTHERAPEUTICS, INC., MD$229,991ZRG1
2016Blockade of histamine-releasing factor as a new prophylactic and therapeutic strategy for food allergy1R41AI124734-01KAWAKAMI, TOSHIAKIMARUYAMA, TOSHIAKIABWIZ BIO, INC., CA$229,600ZRG1
2016STAT Inhibitors for Asthma Therapy1R41AI125007-01A1CORRY, DAVID BATRAPOS THERAPEUTICS, LLC, TX$227,537ZRG1
2016High-speed Intraoperative Assessment of Breast Tumor Margin using MarginPAT1R41CA200006-01A1CHENG, JI-XINVIBRONIX, INC., IN$225,943ZRG1
2016A NEW HOLOGRAPHIC 3D CAMERA FOR FUNDUS IMAGING1R41EY026826-01A1BROOKER, GARYCELLOPTIC, INC., MD$225,635ZRG1
2016A High Resolution Radiation Therapy Dosimetry system1R41CA202980-01A1LI, HAROLD HUIDOSEIMAGING, LLC, MO$225,001ZRG1
2016PEGYLATED PEPTIDES LIGANDS TARGETING RADIATION-INDUCIBLE RECEPTORS ON CANCER1R41CA196002-01A1 · under PA-14-072DEVANATHAN, SRIRAMMEDICAL GUIDANCE SYSTEMS, LLC, MO$225,000ZRG1
2016Aerosol Sampling and Microfluidic Analysis of Reactive Oxygen Species1R42ES026532-01 · under PA-14-072ZYUZIN, ALEXEIILLIONIX, LLC, WA$225,000ZRG1
2016Smaller, Brighter Probes for Correlative Super-resolution and Electron Microscopy1R41GM117974-01 · under PA-14-072POWELL, RICHARD DENISNANOPROBES, INC., NY$225,000ZRG1
2016Developing a novel adjuvant system for therapeutic vaccines against lung cancer1R41CA199956-01A1SHIRWAN, HAVALFASCURE THERAPEUTICS, LLC, KY$225,000ZRG1
2016Development of a kit for characterization of cellular energetics in single cells in cell and tissue cultures based on the measurement of the absolute magnitude of the mitochondrial membrane potential1R41DA043369-01GERENCSER, AKOS AIMAGE ANALYST SOFTWARE, CA$225,000ZRG1
2016Jamboxx: Interactive Respiratory Therapy through Music and Gaming1R42HL132735-01DICESARE, MICHAELMY MUSIC MACHINES, INC., NY$225,000ZRG1
2016Small, high-affinity ligands for array tomography1R41MH110321-01HACKEL, BENJAMINLENZI, DAVID PETERARATOME, LLC, CA$225,000ZRG1
2016PlusOne: Prototyping and Validation of a Wireless In-Home Breathing Monitor for Prevention of Overdose Deaths1R41DA041960-01MAAS, DUSTINPATWARI, NEALPORUCZNIK, CHRISTINAXANDEM TECHNOLOGY, LLC, UT$225,000ZRG1
2016An Agent-Based Modeling Platform for Environmental Biotechnology1R41ES026541-01A1MOFRAD, MOHAMMAD RKSHIRAZI, FATEMEHMICROVI BIOTECH, INC., CA$225,000ZRG1
2016A New Prostate Cancer Treatment to Improve Outcomes and Reduce Side-effects1R41CA210737-01FLYNN, RYAN THOMASPXALPHA, LLC, IA$225,000ZRG1
2016An Automated Patient Chart Error Detection System for Radiation Therapy1R41CA195819-01A1XIA, JUNYIINFONDRIAN, LLC, IA$225,000ZRG1
2016Developing novel RPPA for the detection of metastatic prostate cancer1R41CA210772-01TAO, W. ANDYTYMORA ANALYTICAL OPERATIONS, LLC, IN$225,000ZRG1
2016Validation of a salivary miRNA diagnostic test for autism spectrum disorder1R41MH111347-01MIDDLETON, FRANK A.QUADRANT BIOSCIENCES, INC., NY$225,000ZRG1
2016A simple and effective diagnostic test for gastrointestinal bleeding to improve patient outcomes1R41DK106779-01A1MANNING, HENRY CHARLESCUMBERLAND PHARMACEUTICALS, INC., TN$224,999ZRG1
2016Smart Residential Carpet for Promoting Aging in Place1R41AG053108-01NAJAFI, BIJANBIOSENSICS, LLC, MA$224,999ZRG1
2016A novel protein engineering tool for rapid manufacturing of designer nucleosomes1R41CA214076-01SUN, ZU-WENEPICYPHER, INC., NC$224,999ZRG1
2016Novel small-molecule targeted therapy for prostate cancer1R41CA206725-01A1WU, DAQINGMETCURE THERAPEUTICS, LLC, GA$224,999ZRG1
2016A mobile app to reduce treatment-related financial burden for cancer patients1R42CA210699-01ZAFAR, SYED YOUSUFVIVOR, LLC, NY$224,997ZRG1
2016Stabilization of Influenza Vaccine by Silica-Coating1R41AI126940-01LAIDLER, JAMES RSTEDMAN, KENNETH MARKSTONESTABLE, INC., OR$224,993ZRG1
2016Repurposing Pyrvinium as an Orphan Drug for Familial Adenomatous Polyposis1R41CA196011-01A1 · under PA-14-072ORTON, DARRENSTEMSYNERGY THERAPEUTICS, INC., FL$224,991ZRG1
2016Development of an Osteoinductive Spinal Fusion Implant for Enhanced Fusion Rates1R41AR070088-01FRIIS, ELIZABETH AEVOKE MEDICAL, LLC, KS$224,991ZRG1
2016Personalized dosing of dichloroacetate for the treatment of rare and common diseases1R42HD089804-01STACPOOLE, PETER WALLACEMEDOSOME BIOTEC, LLC, FL$224,978ZRG1
2016Therapeutic Potential of the Potassium Channel Inhibitor SHK-186 for Pediatric Lupus1R41AI122566-01 · under PA-14-072PROBST, PETERSTEVENS, ANNE MARGUERITEKINETA, INC., WA$224,977ZRG1
2016Expanding teleconsent capabilities to improve clinical research recruitment1R41LM012547-01A1WELCH, BRANDON MDOXY.ME, LLC, SC$224,972ZRG1
2016Directed Chemotherapy Delivery for Leptomeningeal Metastases1R41CA206744-01LAD, SHIVANAND PMCCABE, AARON RICHARDMINNETRONIX, INC., MN$224,970ZRG1
2016Discovery of alpha4beta2 Nicotinic Receptor Antagonists as Alcohol Abuse Medications1R41AA025298-01TOLL, LAWRENCE RASSUAGE PHARMACEUTICALS, INC., FL$224,956ZRG1
2016Optimization of Pre- and Post-Operative Pain Management1R41DA043309-01DOORENBOS, ARDITH ZCHANGE MANAGEMENT CONSULTING, LLC, WA$224,949ZRG1
2016Preclinical Evaluation of NCS-382 in Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD)1R41NS098856-01GIBSON, K MICHAELMCCONNELL, ALICESPERAGEN, INC., TX$224,936ZRG1
2016Polar sampling and optimization of protein-ligand cocrystal structures1R41GM116300-01A1BAJAJ, CHANDRAJIT LREYNOLDS, CHARLES H.GFREE BIO, LLC, PA$224,934ZRG1
2016Empowering real-time, web-based genomic big data analysis at commercial scale.1R41HG009096-01MARTH, GABOR TMILLER, CHASEWARD, ALISTAIRFRAMESHIFT LABS, INC., MA$224,920ZRG1
2016Targeted Epigenetic Therapy for Triple-Negative Breast Cancer1R41CA203067-01A1ZHOU, MING-MINGPARKSIDE SCIENTIFIC, INC., NY$224,890ZRG1
2016A Platform Technology for High-Throughput Screening of Gene Regulatory Elements1R41GM119914-01A1CRAWFORD, GREGORY EGERSBACH, CHARLES A.REDDY, TIMOTHY EELEMENT GENOMICS, INC., NC$224,881ZRG1
2016Peripheral Nerve-on-a-chip for Predictive Preclinical Pharmaceutical Testing1R41TR001270-01A1 · under PA-14-072CURLEY, JABE LMOORE, MICHAEL JAXOSIM, INC., LA$224,859ZRG1
2016Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons1R41DA041959-01MEHALSO, ROBERTSENSODX II, LLC, NY$224,840ZRG1
2016Novel Medical Food for the Management of Iron Deficiency Anemia1R41DK105656-01A1WOLFE, DARRENSIDERO BIOSCIENCE, LLC, PA$224,836ZRG1
2016Novel mechanism for the treatment of epilepsy: New Vitamin K analogs target energetics and have low toxicity due to excellent specificity and low dose requirements compared to current therapies1R41NS097047-01CHAN, SHERINE SNEUROENE THERAPEUTICS INC, DC$224,804ZRG1
2016Development of DRα1-MOG-35-55 for treatment of DR2 negative MS subjects1R41AI122574-01 · under PA-14-072VANDENBARK, ARTHUR A.VIROGENOMICS BIODEVELOPMENT, INC., OR$224,796ZRG1
2016Preclinical Testing of Tetrandrine against Noise-Induce Hearing Loss1R41AT008922-01A1BAO, JIANXINGATEWAY BIOTECHNOLOGY, INC., MO$224,701ZRG1
2016Shape RNA Structure Analysis for Drug Discovery and Translational Research1R43GM116274-01 · under PA-14-072WARNER, KATHERINE DEIGANRIBOMETRIX, LLC, NC$224,700ZRG1
2016Controlled Release Polymer Structures for In Situ Chemical Oxidation of Contaminated Groundwater1R41ES026916-01CARPENTER, ALEXIS WELLSAXNANO, LLC, NC$224,670ZRG1
2016Assessment of the glucagon receptor blocker REMD-477 on insulin requirements in type 1 diabetes1R42DK108305-01 · under PA-14-072KLEIN, SAMUELTHAI, DUNG LREMD BIOTHERAPEUTICS, INC., CA$224,664ZRG1
2016SHAPE RNA Bioinformatics for Therapeutics and Translational Research1R41GM117712-01 · under PA-14-072WEEKS, KEVIN MRIBOMETRIX, LLC, NC$224,636ZRG1
2016Device for Treatment of Congenital Diaphragmatic Hernia1R41HL131250-01 · under PA-14-072GOLDMAN, KENNETH GLENH-CUBED, INC., OH$224,634ZRG1
2016improving Cas9 mediated homologous recombination in pluripotent stem cells1R41GM115028-01A1 · under PA-14-072ZHANG, JIFENGAPPLIED STEMCELL, INC., CA$224,518ZRG1
2016Engineering stem cells to make mucopolysaccharidosis IIIB1R41NS092221-01A1 · under PA-14-072EKINS, SEANPHOENIX NEST, INC., NY$224,469ZRG1
2016Novel therapies for inherited muscle diseases1R41AR068158-01A1 · under PA-14-072KANG, PETER B.MEDOSOME BIOTEC, LLC, FL$224,463ZRG1
2016Cognitive Change Battery: An Assessment for Serial Administration1R41AG052218-01A1MAYR, ULRICH ERODE, CATRINCOGMETRIC, LLC, OR$224,370ZRG1
2016CellRaft Array for Screening and Isolation of Highly Effective Cytotoxic T Cells1R41AI126905-01ALLBRITTON, NANCY L.CELL MICROSYSTEMS, INC., NC$224,129ZRG1
2016Cancer Imaging and Therapy Platform1R41CA213601-01WILSON, DAVID LYNNBIOINVISION, INC., OH$224,116ZRG1
2016New piperazines effecting Abeta oligomer displacement from neuronal receptors1R41AG052252-01 · under PA-14-072IZZO, NICHOLAS JOHNCOGNITION THERAPEUTICS, INC., PA$224,002ZRG1
2016Lipidated Stable BAM8-22 Offers a Promising Therapeutic for Neuropathic Pain1R41NS095436-01 · under PA-14-072KOPIN, ALAN SON TARGET THERAPEUTICS, LLC, MA$223,900ZRG1
2016Dual-view endoscopic probe1R41CA203212-01 · under PA-14-072BANERJEE, BHASKARCOOMBS, DAVIDOMNISCIENT IMAGING, INC., AZ$223,761ZRG1
2016Sample-free onsite detection of cocaine using microneedles via laser-treated skin1R41DA041003-01 · under PA-14-072WU, MEI XXIE, XINMIN SIMONAFASCI, INC., CA$223,633ZRG1
2016Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma1R41CA213488-01MARCOUX, FRANK W.LEUKOGENE THERAPEUTICS, INC., SC$222,958ZRG1
2016Delivery of pathogen-trapping antibodies for vaginal protection1R41AI122472-01 · under PA-14-072MOENCH, THOMAS RAYMUCOMMUNE, LLC, NC$222,725ZRG1
2016Development of a non-fibrillic amyloid-beta oligomer selective positron emission tomography imaging diagnostic for Alzheimer.1R41AG054337-01KLEIN, WILLIAM LACUMEN PHARMACEUTICALS, INC., VA$222,192ZRG1
2016Advanced Polymer-Based Micro-sensor for Radiation Detection and Measurement1R41ES027389-01A1HOBSON, STEPHEN TERRENCESEACOAST SCIENCE, INC., CA$221,432ZRG1
2016An eHealth solution for posttraumatic stress and pain screening integrated in pediatric injury care1R41HD087021-01 · under PA-14-072KASSAM-ADAMS, NANCYMCLAUGHLIN, JEFFERYRADIANT CREATIVE GROUP, LLC, TX$220,945ZRG1
2016Development of a Genotype-linked Antibiotic Resistance Platform for Real Time Pathogen Risk Classification and Epidemiology1R41AI122740-01A1CHAN, PATRICIAMAVERIX BIOMICS, INC., CA$219,655ZRG1
2016Nanoliter electron paramagnetic resonance sensor based on diamond nanophotonics: a new tool for biomarker monitoring1R41GM119925-01ACOSTA, VICTOR MARCELJARMOLA, ANDREJSODMR TECHNOLOGIES, INC., CA$216,281ZRG1
2016Nasal Leptin - Polymer Conjugate for Treatment of Obesity1R41DK108466-01A1KABANOV, ALEXANDER VNEURO10-9 PHARMA, INC., NC$215,843ZRG1
2016Selective inhibition of CYP26A1 in the skin for the treatment of ichthyosis1R41AR069416-01A1ASTRUC DIAZ, FANNYDERMAXON, LLC, MT$215,640ZRG1
2016A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes1R41AR068202-01A1 · under PA-14-072LOTZ, JEFFREY C.BIONIKS, INC., CA$215,600MRS
2016Improved Otologic Implants On Demand Intraoperatively with 3D CAD/CAM Autografts1R41DC015408-01KNOX, ALISAKNOX, GLENNNITINETICS, LLC, FL$214,976ZRG1
2016Technology for Synthesis of Chemically Diverse RNAs1R41GM121103-01SOUSA, RUI J.BIOLYTIC LAB PERFORMANCE, INC., CA$213,601ZRG1
2016Novel Dental Adhesives to Prevent Recurrent Caries1R41DE026085-01RENNE, WALTER G.CURE INNOVATIONS, LLC, SC$211,441ZRG1
2016Developing an Affordable and Pocketable POC Device for Monitoring Lithium and Sodium in Patients with Bipolar Disorder1R41MH111337-01LAN, TIANGLUCOSENTIENT, INC., IL$210,971ZRG1
2016"Speed Bumps": A non-invasive quantitative test for early detection of neuropathy in the feet1R41NS097120-01A1KENNEDY, WILLIAM RNEURO DEVICES, INC., MN$210,245ZRG1

Showing the 200 most recent of 559 awards.

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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