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NIH funding notice PA-16-303

PHS 2016-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])

Closed on April 5, 2017.

Posted
June 3, 2016
Close date
April 5, 2017
Activity codes
R41, R42
Institutes taking part
NCI, NEI, NHLBI, NHGRI, NIA, NIAAA, NIAID, NIAMS, NIBIB, NICHD, NIDCD, NIDCR, NIDDK, NIDA, NIEHS, NIGMS, NIMH, NINDS, NINR, NIMHD, NLM, NCCIH, NCATS, DPCPSI, ORIP

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PA-15-270 PHS 2015-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  2. 2 steps back: PA-14-072 PHS 2014-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]
  3. 3 steps back: PA-13-235 Reissue PHS 2013-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  4. 4 steps back: PA-13-089 PHS 2013-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  5. 5 steps back: PA-12-089 PHS 2012-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  6. 6 steps back: PA-11-097 PHS 2011-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  7. 7 steps back: PA-10-051 PHS 2010-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
  8. 8 steps back: PA-09-081 PHS 2009-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])

Replaced by PA-17-303.

Who won it before

758 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $239,556,000 in first-year total cost, median $225,000.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ETTN-M (11)]55
  2. Special Emphasis Panel[ZRG1 SBIB-T (10)]52
  3. Special Emphasis Panel[ZRG1 OTC-T (10)]48
  4. Special Emphasis Panel[ZRG1 ETTN-G (12)]35
  5. Special Emphasis Panel[ZRG1 RPHB-C (10)]33

Most frequent institutions

  1. FOX CHASE CHEMICAL DIVERSITY CENTER, INC7
  2. MEDOSOME BIOTEC, LLC7
  3. MICROBIOTIX, INC6
  4. CORTICOMETRICS, LLC5
  5. FIREBIRD BIOMOLECULAR SCIENCES, LLC5
Competing awards under PA-16-303 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2018Testing a male oral contraceptive targeting Eppin2R42HD084077-02ORAND, MICHAEL GENEEPPIN PHARMA, INC., NC$1,097,562ZRG1
2018Electronic Optimization of Stem Cell Derived Human Cardiac Myocytes2R42HL127901-02A1BETT, GLENNA C LCYTOCYBERNETICS, INC., NY$748,969ZRG1
2018Immuno-CometChip for Human Skin Basal Cell Genotoxicity Testing2R42ES026908-02GEORGE, JAYROSENTHAL, DEANSYKORA, PETERAMELIA TECHNOLOGIES, LLC, DC$666,400ZRG1
2018Novel Indication for Myeloid Progenitor Use: Induction of Tolerance in Solid Organ Transplantation2R42AI108016-02A1DOMEN, ADRIANUS G.W.PANUGANTI, SWAPNACELLERANT THERAPEUTICS, INC., CA$573,592ZRG1
2018A software tool for objective identification of concussion-related vision disorders using a novel eye-tracking device1R41NS103698-01A1MASTER, CHRISTINA L.OCULOGICA, INC., NY$503,162ZRG1
2018Nucleobase aminosugars with reduced ototoxicity1R41DC016257-01A1ARYA, DEV PRIYANUBAD, LLC, SC$305,919ZRG1
2018Development of a Designer Proline-rich antimicrobial peptide Chaperone protein inhibitor (DPC) for treating multi-drug resistant wound infections1R41AI136072-01KRAUS, CARL NEILARREVUS, INC., NC$300,000ZRG1
2018Discovery of Zika virus therapeutics using a replicon assay1R41AI136126-01BOWLIN, TERRY L.MICROBIOTIX, INC, MA$300,000ZRG1
2018Innovative Nose-to-Brain Anticancer Drug Transport Facilitated by NEO1001R41CA217551-01A1CHEN, THOMAS C.WANG , WEIJUNNEONC TECHNOLOGIES, INC., CA$300,000ZRG1
2018Glycoengineering a bioconjugate vaccine against Klebsiella pneumoniae1R41AI136233-01FELDMAN, MARIOVAXNEWMO, LLC, MO$299,999ZRG1
2018Preclinical studies of Selective and Orally Bioavailable Aurora B Inhibitors for the Treatment of AML1R41CA224830-01FRETT, BRENDAN ANDREWGUZMAN, MONICA LLI, HONG YUSYNACTIX PHARMACEUTICALS, INC., AZ$299,975ZRG1
2018Development of KLS-13019 for Chemotherapy Induced Peripheral Neuropathy and Drug Dependence1R41DA044898-01BRENNEMAN, DOUGLAS ERICWARD, SARA JKANNALIFE SCIENCES, INC., NY$299,916ZRG1
2018Quantifying NETosis via Automated High Content Imaging Convolutional Neural Networks1R41AI131840-01A1ELSHERIF, LAILAEPICYPHER, INC., NC$299,751ZRG1
2018Enhancing Clinical Therapy for wet Age-related Macular Degeneration (wetAMD)1R41EY028839-01COOK, JASONNANOHYBRIDS, INC., TX$297,786ZRG1
2018Humanized EMAP II mAb as a Novel Therapy for Viral-Associated Lung Injury1R41HL135945-01A1BOGATCHEVA, NATALIACLAUSS, MATTHIASALLINAIRE THERAPEUTICS, LLC, OH$281,155ZRG1
2018A cell-free, high-throughput screening service for accelerated GPCR ligand discovery1R41GM126674-01SONDEK, JOHN EKXT, BIO INC., NC$276,339ZRG1
2018Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain Injury1R42NS105238-01HUETTEMANN, MAIKSANDERSON, THOMAS HUDSONMITOVATION, INC., MI$248,042ZRG1
2018Noninvasive placement and activation of deep-brain stimulating magnetic particles for reduction of drug-seeking behaviors1R41DA045398-01VASSOLER, FAIR MWEINBERG MEDICAL PHYSICS, LLC, MD$229,701ZRG1
2018MRI-compatible and integrated devices for simultaneous neural recording, stimulation, imaging1R41NS105298-01IRAZOQUI, PEDROMR-LINK, LLC, IN$228,325ZRG1
2018Retinal eye-tracking for the prognosis and monitoring of multiple sclerosis1R41NS100222-01A1SHEEHY, CHRISTY KATHLEENC. LIGHT TECHNOLOGIES, INC., CA$225,392ZRG1
2018Intravascular molecular-structural NIRF-IVUS imaging of coronary artery disease1R41HL140671-01JAFFER, FAROUC AMININTRAVASCULAR IMAGING, INC., MA$225,000ZRG1
2018Production and Characterization of Human Immunoglobulin Producing Goats for Diagnostic Reagents and Therapeutics1R41AI131823-01A1POLEJAEVA, IRINA A.SULLIVAN, EDDIE JSAB CAPRA, LLC, UT$225,000ZRG1
2018Embryonic stem cell high throughput screen accurately reports toxic stress1R41ES028991-01ABDULHASAN, MOHAMMEDRAPPOLEE, DANIEL ALLENREPRODUCTIVE STRESS; MEASUREMENT, MECHANISMS AND MANAGEMENT, CORPORATION, MI$225,000ZRG1
2018Enzymatic attachment of proteins to fluorescent nanodiamond surfaces.1R41GM126603-01RAMPERSAUD, ARFAANWOOD, DAVID WCOLUMBUS NANOWORKS, INC., OH$225,000ZRG1
2018Building an evidentiary case for circulating GHBP as a biomarker for drug-associated stunting of growth1R41HD094622-01DAMSKER, JESSEREVERAGEN BIOPHARMA, INC., MD$224,998ZRG1
2018A universal eye drop adherence monitor to measure and improve adherence to ocular medications1R41EY028807-01MANSBERGER, STEVEN LPORTER, JOSE DUNIVERSAL ADHERENCE, LLC, OR$224,997ZRG1
2018TFEB Activator for Alzheimer’s Disease Therapy1R41AG058364-01LI, YANGMEIBRILLIANT BIOSCIENCES, INC., FL$224,997ZRG1
2018Innovative TME-specific Pro-CAR T-cells for Immunotherapy of Solid Tumors1R41CA224652-01HUANGPU, JUNPANACISE BIO, INC., NC$224,991ZRG1
2018Novel Targeting of the S1P Receptor, S1P1, and Nox4 as Therapeutic Approaches in ARDS1R41HL140741-01GARCIA, JOE G. N.RESTORE THERAPEUTICS, LLC, AZ$224,984ZRG1
2018Oxidation-resistant Anti-protease Therapy1R42HL140670-01CRYSTAL, RONALD GLEXEO THERAPEUTICS, LLC, NY$224,967ZRG1
2018Interventions to Improve Reproductive Health among Adolescents1R41HD094406-01CHINMAN, MATTHEWFIRPO-TRIPLETT, REGINADFUSION, INC., CA$224,957ZRG1
2018Reopening the Central Airway With Needle-Size Tentacle Manipulators1R41HL140709-01WEBSTER, ROBERT JAMESVIRTUOSO SURGICAL, INC., TN$224,598ZRG1
20183D Holographic Guidance, Navigation, and Control (3D GN&C) for Endovascular Aortic Repair (EVAR)1R41HL139290-01A1WEST, KARLCENTERLINE BIOMEDICAL, INC., OH$223,868ZRG1
2018MtLDL detection to diagnose childhood tuberculosis1R41AI136071-01SAMPSON, NICOLE SCHRONUS PHARMACEUTICALS, INC., NY$223,406ZRG1
2018staRt: Enhancing speech treatment with smartphone-delivered biofeedback1R41DC016778-01MCALLISTER, TARAGIRLFRIENDS LABS, LLC, NY$222,939ZRG1
2018Reprogrammed T Cells to prevent graft versus host disease1R41AI136755-01A1BELLUCCI, JOSEPH JELEMENT GENOMICS, INC., NC$221,507ZRG1
2018Highly selective detection of tau oligomers in biological fluids for the diagnosis of Alzheimer's Disease1R42AG058333-01SOTO, CLAUDIOVOLLRATH, BENAMPRION, INC., CA$217,647ZRG1
2018An Engineered Nanoimmunotherapy for Melanoma1R41CA217294-01A1FERNANDES, ROHANSWEENEY, ELIZABETH EVILLAGRA, ALEJANDRO VIMMUNOBLUE, LLC, MD$200,001ZRG1
2018Commercialization of a Rapid Blood Test for Traumatic Brain Injury1R41NS102118-01A1LOVELL, MARK ANTHONYFAWKES BIOTECHNOLOGY, LLC, KY$197,824ZRG1
2018The Kappa Partial Agonist PPL-103 as a Potential Cocaine Abuse Pharmacotherapy1R41DA044894-01A1TOLL, LAWRENCE RPHOENIX PHARMALABS, INC., UT$186,687ZRG1
2018Numeric Expansion of CD-19 Specific T cells in Magnetic 3D Culture1R41AI136225-01NAJJAR, AMER MTSENG, HUBERTNANO3D BIOSCIENCES, INC., TX$175,849ZRG1
2018Inter-examiner Agreement of a Novel Device for the Measurement of Cervical Dilation in Labor: A Randomized Controlled Trial1R41HD094398-01BERGHELLA, VINCENZOELM TREE MEDICAL INC., CA$168,683ZRG1
2018Developing an efficient E-cigarette aerosol generation and exposure system for rodent models with aerosol characteristics equivalent to those inhaled by E-cigarette users1R41DA044788-01KEWEKORDES, JOSEFSHAO, XUESI MAXAUTOMATE SCIENTIFIC, INC., CA$150,000ZRG1
2017Development of the first-in-class novel dual PI-3K/BRD4 inhibitor SF25232R42CA192656-02A1MORALES, GUILLERMO ASIGNALRX PHARMACEUTICALS, INC., GA$1,320,558ZRG1
2017An Accessible Digital Intervention to Promote HIV Testing/Counseling and Prevention Among Adolescents2R42HD088317-02FIELLIN, LYNN ELIZABETHSCHELL, JESSESCHELL GAMES, LLC, PA$1,100,650ZRG1
2017Peripheral FAAH as a target for novel analgesics2R42DA033683-02A1 · under PA-14-072PIOMELLI, DANIELEANTEANA THERAPEUTICS, INC., CA$1,100,244ZRG1
2017Urine Diagnostics for Aspergillosis2R42AI115866-02A1MARR, KIEREN A.PEARL DIAGNOSTICS, INC., MD$1,004,193ZRG1
2017Validation of Novel Therapeutic Approach for Cryptococcal Meningitis2R42AI120304-02 · under PA-15-270LAD, SHIVANAND PMCCABE, AARON RICHARDMINNETRONIX, INC., MN$1,000,000ZRG1
2017Peripheral Nerve-on-a-chip for Predictive Preclinical Pharmaceutical Testing2R42TR001270-02CURLEY, JABE LMOORE, MICHAEL JAXOSIM, INC., LA$963,541ZRG1
2017Aspirin-PC for Chemoprevention of Colorectal Cancer2R42CA171408-02A1LICHTENBERGER, LENARD MPLX OPCO, INC., TX$961,499ZRG1
2017Albumin Nanoparticles Incorporating Piceatannol (PANPs) for ALI/ARDS therapy2R42HL126456-03A1KANTETI, PRASAD V. S.MALIK, ASRAR B.CELL BIOLOGICS, INC., IL$959,212ZRG1
2017Interactive technology for media literacy drug prevention in community groups2R42DA039595-02A1GREENE, KATHRYN LHECHT, MICHAELREAL PREVENTION, LLC, NJ$873,000ZRG1
2017Design and Development of Immunotolerant S. aureus Biotherapies2R42AI118133-02 · under PA-15-270BAILEY-KELLOGG, CHRISGRISWOLD, KARL ELYTICON, LLC, NH$868,526ZRG1
2017Broadly Protective Bispecific Antibodies for Treatment of Ebola Virus Disease2R42AI122403-02AMAN, M JAVADLAI, JONATHAN R.INTEGRATED BIOTHERAPEUTICS, INC., MD$861,259ZRG1
2017Development of user-friendly fluorescence based assays for marine toxins2R42ES023724-02A1 · under PA-15-270MCCALL, JENNIFER RETTEWSEATOX RESEARCH, INC., NC$854,503ZRG1
2017Lactoferrin Modulation of Granuloma Pathology2R42AI117990-02 · under PA-15-270ACTOR, JEFFREY KKRUZEL, MARIAN LPHARMAREVIEW CORPORATION, TX$815,321ZRG1
2017CellRaft Array for Screening and Isolation of Highly Effective Cytotoxic T Cells2R42AI126905-02ALLBRITTON, NANCY L.ARMISTEAD, PAUL MICHAELCELL MICROSYSTEMS, INC., NC$801,389ZRG1
2017Clinical Translation of Augmented Reality Visualization for Laparoscopic Surgery2R42CA192504-02 · under PA-15-270SHEKHAR, RAJIGI TECHNOLOGIES, INC., MD$774,136ZRG1
2017AutoRegister: A system for enhancing the accuracy of tumor change detection2R42CA183150-02 · under PA-15-270VAN DER KOUWE, ANDRE JAN WILLEMWIGHTON, PAULCORTICOMETRICS, LLC, MA$750,000ZRG1
2017Bone targeted antimicrobials for biofilm-mediated osteolytic infection treatment2R42DE025789-02EBETINO, FRANK H.SEDGHIZADEH, PARISH PAYMONBIOVINC, LLC, CA$750,000ZRG1
2017Restimulating memory T cell responses in elderly by a novel, live influenza vaccine2R42AI120269-02BILSEL, PAMUKIWASAKI, AKIKOFLUGEN, INC., WI$746,327ZRG1
2017Improvements to Biopharmaceutical Manufacturing2R42GM114935-02SHARFSTEIN, SUSAN THOCUSLOCUS, INC., NY$733,711ZRG1
2017Microfluidic Nitric Oxide Sensor2R42AI112064-03CAIRNS, BRUCE AMCDUNN, JONATHAN EDWARDCLINICAL SENSORS, INC., NC$723,682ZRG1
2017An eHealth solution for posttraumatic stress and pain screening integrated in pediatric injury care2R42HD087021-02A1KASSAM-ADAMS, NANCYMCLAUGHLIN, JEFFERYRADIANT CREATIVE GROUP, LLC, TX$715,833ZRG1
2017Development of DRα1-MOG-35-55 for treatment of DR2 negative MS subjects2R42AI122574-02VANDENBARK, ARTHUR A.VIROGENOMICS BIODEVELOPMENT, INC., OR$702,706ZRG1
2017Tissue Engineered Intestine2R42DK107168-02BESNER, GAIL EJOHNSON, JED KIZERNANOFIBER SOLUTIONS, LLC, OH$694,464ZRG1
2017Noninvasive Contrast Enhanced Early Detection of Melanoma Liver Metastasis2R42CA183376-02YANG, JENNY J.INLIGHTA BIOSCIENCES, LLC, GA$602,227ZRG1
2017Small Molecule Therapy for the Treatment of Heart Failure1R42HL132684-01A1HAJJAR, ROGER J.SUMOCOR, LLC, NJ$550,612ZRG1
2017Nutritional Therapy in Elderly with Heart Failure2R42AG050375-02WOLFE, ROBERT RESSENTIAL BLENDS, LLC, AK$544,749ZRG1
2017Science Take-Out Kits for Environmental Health Education2R42ES023706-02HOLT, SUSANMARKOWITZ, DINA GROSSMANSCIENCE TAKE-OUT, LLC, NY$524,883ZRG1
2017Advanced Assessment to Accelerate Diagnostic Skill Acquisition, Phase II2R42GM108104-02A1CIANCIOLO, ANNALAVOIE, NOELLEPARALLEL CONSULTING, LLC, CA$500,000ZRG1
2017Augmenting Dual Energy CT for Novel Contrast Agents2R42DK104580-02A1YEH, BENJAMIN MNEXTRAST, INC., CA$499,999ZRG1
2017Receptors, Ligands, and Catalysts on Demand using Expanded Genetic Alphabets2R42GM115130-02BENNER, STEVEN AYANG, ZUNYIFIREBIRD BIOMOLECULAR SCIENCES, LLC, FL$499,573ZRG1
2017Expressing humanized bacterial luciferase in stem cells: Moving beyond fireflyluciferase to expand the informational capacity of animal models for regenerativemedicine2R42GM116622-02MORRISON, DAN490 BIOTECH, INC., TN$496,198ZRG1
2017Development of Pirenzepine for HIV-SN1R41NS105177-01FIELDS, JEREL ADAMMIZISIN, ANDREWWINSANTOR, INC., CA$466,421ZRG1
2017Numerical Tools for Predicting Drug Dissolution Profiles2R42GM090513-02A1PARK, TAESHINRES GROUP, INC., MA$450,920ZRG1
2017Development of a Clinical Screening Platform for Type 1 Diabetes1R42DK115296-01WAGNER, DAVID H.OP-T-MUNE, INC., CO$421,182ZRG1
2017Novel Treatment for Traumatic Brain Injury1R41NS098903-01A1TUCCI, FABIO COHENUTESHEV, VICTOR VEPIGEN BIOSCIENCES, INC., CA$417,267ZRG1
2017ErythroMer: Nanoscale Bio-Synthetic Red Cell Substitute1R42HL135965-01A1DOCTOR, ALLANKALOCYTE, INC., MD$397,622ZRG1
2017Development of PAR4 Pepducins as a Novel Antithrombotic Treatment1R41HL134517-01A1 · under PA-15-270KULIOPULOS, ATHANOASIS PHARMACEUTICALS, MA$366,484ZRG1
2017Anti-CCL25 mAb to treat castration resistant prostate cancer1R41CA214080-01 · under PA-15-270SINGH, SHAILESHJYANT, INC., GA$350,000ZRG1
2017A Novel Probiotic Platform to Treat Necrotizing Enterocolitis1R41GM122130-01A1BESNER, GAIL EGOODMAN, STEVEN DMONON BIOVENTURES, LLC, IN$331,395ZRG1
2017A novel approach to treat non-alcoholic steatohepatitis (NASH)1R41DK112429-01A1RINCON, MERCEDESMITOTHERAPEUTIX, LLC, CT$317,953ZRG1
2017Methamphetamine vaccine for Humans1R42DA043311-01A1KOGAN, YAKOVKOSTEN, THOMASKADVAX TECHNOLOGIES, INC., TX$305,976ZRG1
2017HLS- Cyclic CAR peptide: a targeted therapy for pulmonary hypertension1R42HL132742-01A1YU, PAUL BVASCULAR BIOSCIENCES, CA$302,402ZRG1
2017Vastly improved influenza diagnostics through the development of a handheld thermal contrast reader1R41NR017825-01A1BISCHOF, JOHN CVIGILANT DIAGNOSTICS, LLC, MN$300,939ZRG1
2017Identification of Small Molecule Amyloid Beta Peptide Reducing Agent1R41AG058517-01NEFZI, ADELSMART BIOMOLECULES, INC., FL$300,001ZRG1
2017Aminooxyacetic Acid Prodrugs for Colon Cancer Therapy1R41CA213463-01 · under PA-15-270SZABO, CSABACBS THERAPEUTICS, INC., TX$300,000ZRG1
2017Inhibitors of Hydrogen Sulfide Metabolism as a Novel Treatment for Heart Failure1R41HL134435-01A1JORNS, MARILYN SFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$300,000ZRG1
2017Development of Zika viral pseudoinfectious virus as Zika vaccine candidate1R41AI129119-01A1PANG, XIAOWUZHOU, YANFEITENGEN BIOMEDICAL CO., MD$300,000ZRG1
2017Therapeutic antibodies for treatment of hantavirus cardiopulmonary syndrome1R41AI132047-01BOTTEN, JASON W.FANGER, MICHAEL WCELDARA MEDICAL, LLC, NH$300,000ZRG1
2017Robust Predictor of Breast Cancer Risk1R41CA217383-01A1OSTRER, HARRYMORGAN AND MENDEL GENOMICS, INC., DE$300,000ZRG1
2017Polyionic Papillomavirus-like Particles (VLP) for the Treatment of HPV+ oropharyngeal squamous cell carcinomas (OPCs)1R41CA224469-01WANG, JOSHUA WEIYUANPATHOVAX, LLC, MD$300,000ZRG1
2017DEVELOPMENT OF A NOVEL ANTIVIRAL TO TREAT AND PREVENT ACYCLOVIR RESISTANCE IN HUMAN OCULAR HERPES KERATITIS1R41EY026849-01A1 · under PA-15-270RICCIARDI, ROBERT PAULFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$299,999ZRG1
2017Regulators of NaV1.7 Channels: Novel Anti-Allodynic Drug Candidates1R41CA210857-01A1KHANNA, RAJESHREGULONIX, LLC, NY$299,999ZRG1
2017Development, Characterization & Commercialization of a Viably Frozen, Patient-Inclusive Hepatocellular Carcinoma Tumor Bank1R41CA213678-01A1BRIGGS, MICHAELDUDA, DAN GABRIELWOODLAND PHARMACEUTICALS, LLC, MA$299,999ZRG1
2017Caveolae-Targeted Cisplatin Immunoconjugates for Effective Lung Cancer Therapy1R41CA217399-01A1LEVIN, MICHAEL DAVIDCAVATAR, LLC, CA$299,999ZRG1
2017UV-emitting nanoparticles as novel radiation sensitizers targeting hypoxic cells1R41CA206645-01A1PURSCHKE, MARTINSQUILLANTE, MICHAEL R.RADIATION MONITORING DEVICES, INC., MA$299,992ZRG1
2017A practical and versatile high-resolution 3D dosimetry system for clinical use1R41CA217421-01A1ADAMOVICS, JOHN ARNEOLDHAM, MARKHEURIS, INC., NJ$299,962ZRG1
2017Raising the Therapeutic Index of Photodynamic Therapy with Targeted Nanosyringes1R41CA221420-01COOK, JASONNANOHYBRIDS, INC., TX$299,945ZRG1
2017Validation of a Diagnostic Test for Borrelia miyamotoi1R41AI134497-01LEDIZET, MICHELL2 DIAGNOSTICS, LLC, CT$299,905ZRG1
2017Improved detection of bladder cancer recurrence using a biophysical biomarker1R41CA213584-01A1HENRY, MICHAEL DSYNDERBIO, INC., IA$299,860ZRG1
2017DRα1-MOG: A Novel Immunomodulatory Therapeutic for Stroke1R41NS103644-01ALKAYED, NABIL JVIROGENOMICS BIODEVELOPMENT, INC., OR$299,186ZRG1
2017Screening for the autoimmune component of multiple sclerosis1R41AI129571-01A1WAGNER, DAVID H.OP-T-MUNE, INC., CO$299,002ZRG1
2017Development of the first thermolytic to suppress shivering and seizure1R41HL135964-01A1DREW, KELLY LBE COOL PHARMACEUTICS, LLC, AK$298,871ZRG1
2017Targeting STT3A and STT3B to Block Flavivirus Replication1R41AI134531-01VAN ZANDT, MICHAEL CHRISTOPHERNEW ENGLAND DISCOVERY PARTNERS, LLC, CT$298,652ZRG1
2017Development of Pirenzepine for CIPN1R41CA213555-01A1MIZISIN, ANDREWWINSANTOR, INC., CA$298,550ZRG1
2017GRIM19 for head and neck cancer therapy1R41CA217438-01A1KALVAKOLANU, DHAN V.GLYCOMANTRA, INC., MD$298,517ZRG1
2017Probabilistic Modeling for Software-Guided Radiotherapy Patient Plan QA1R41CA217452-01A1KALET, ALAN M.SUN NUCLEAR CORPORATION, FL$297,681ZRG1
2017Developing a small peptide to control autoimmune inflammation in type 1 diabetes1R41AI131784-01WAGNER, DAVID H.OP-T-MUNE, INC., CO$297,387ZRG1
2017Novel Inhibitors of PSMB7 and PSMB10 for the Treatment of Multiple Myeloma1R41CA221494-01A1KISSELEV, ALEXEIPLETNEV, ALEXANDREINHIPROT, LLC, AL$296,354ZRG1
2017Fc-folate Conjugate for the Treatment of Triple Negative Breast Cancer1R41CA213548-01A1SPEYER, CECILIA LNEULINK, INC., MI$295,747ZRG1
2017Development of PTI-125-DX, a blood-based diagnostic for Alzheimer's disease1R42AG057329-01BURNS, LINDSAY HTHORNTON, GEORGE BENWANG, HOAU-YANCASSAVA SCIENCES, INC, TX$295,343ZRG1
2017Infection Site Targeted Antitoxin Antibody (ISTAb) against Bacillus anthracis1R41AI122666-01A1 · under PA-15-270ADHIKARI, RAJAN PHAKAMI, RAMIN M.NELSON, DANIEL C.INTEGRATED BIOTHERAPEUTICS, INC., MD$294,932ZRG1
2017Scientific Merit and Feasibility of Fructokinase Inhibition for Obesity2R42DK104432-02JOHNSON, RICHARD JOSEPHCOLORADO RESEARCH PARTNERS, LLC, CO$289,373ZRG1
2017Enabling point-of-care molecular diagnostics by developing an adaptive PCR instrument and on-demand kit reagents1R42HG009470-01A1ADAMS, NICHOLAS MDAWSON, ELLIOTT PAULHASELTON, FREDERICK RBIOVENTURES, INC., TN$287,251ZRG1
2017Large Scale Preparation of Natural Glycans1R41GM122139-01 · under PA-15-270SONG, XUEZHENGNATGLYCAN, LLC, GA$285,524ZRG1
2017Osteopontin-targeted therapy for primary CNS lymphoma1R41CA210669-01A1COPLAND, JOHN A.TUN, HAN WMODULATION THERAPEUTICS, INC., WV$283,986ZRG1
2017Cell-penetrating antimicrobial therapeutics for treatment of complicated skin and soft tissue infections1R41AI132102-01LIPKA, ELKETSRL, INC., MI$283,958ZRG1
2017Development of a new small molecule therapeutic for the treatment of resistant breast cancer1R41CA210877-01A1LOUIE, STAN GEEPETASIS, NICOS AVIOMEDIX, LLC, CA$279,906ZRG1
2017Effects of LGM2605 on a Primate Model of Asthma1R41AI132012-01HACZKU, ANGELASIELECKI, THAIS MOTRIALIGNAMED, LLC, PA$277,792ZRG1
2017Development of a POEGMA-Aptamer rapid onset anticoagulant that eliminates antigenicity to anti-PEG antibodies1R41HL139234-01CHILKOTI, ASHUTOSHGATEWAY BIO, INC., NC$277,130ZRG1
2017Development of MTX-211 for the Treatment of KRAS Mutant Colorectal Cancer1R41CA213715-01 · under PA-15-270LEOPOLD, JUDITH SWHITEHEAD, CHRISTOPHER EMILMEKANISTIC THERAPEUTICS, LLC, MI$275,000ZRG1
2017Next Generation Regenerative Therapy with Pim-1 Enhanced Cardiac Progenitor Cells1R41HL137602-01SUSSMAN, MARK ALANCARDIOCREATE, INC., CA$265,893ZRG1
2017Developing Multi-targeting Antiviral Agents Against Herpes Simplex 11R41AI134509-01WELLER, SANDRA KQUERCUS MOLECULAR DESIGN, LLC, CT$258,940ZRG1
2017Visually-driven disease variant analysis empowering real-time clinical research.1R41HG009629-01MARTH, GABOR TMILLER, CHASEWARD, ALISTAIRFRAMESHIFT LABS, INC., MA$256,443ZRG1
2017High throughput CRISPR/Cas9 cell line generation using the CellRaft Array platform1R41HG009467-01A1MARZLUFF, WILLIAM F.CELL MICROSYSTEMS, INC., NC$250,780ZRG1
2017Online Practitioner Training in Behavioral Intervention in Autism: Skill Training Using an Interactive Simulated Child1R41MH116534-01A1 · under PA-15-270SERNA, RICHARD WPRAXIS, INC., MA$250,387ZRG1
2017Recombinant Silk Elastin-like Protein Polymers for the Embolization of Cerebral Aneurysms1R41NS100184-01A1CHENEY, DARWIN LEROYGHANDEHARI, HAMIDTHERATARGET, UT$250,000ZRG1
2017Novel iobio analysis supporting genome scale data quality control.1R43HG009868-01MARTH, GABOR TMILLER, CHASEWARD, ALISTAIRFRAMESHIFT LABS, INC., MA$249,846ZRG1
2017Development and Validation of SafeClose Mesh Augmentation System for Hernia Prevention1R41GM123789-01A1FISCHER, JOHN PATRICKPARADIGM SURGICAL, LLC, PA$243,070ZRG1
2017A novel anti-gonorrhea immunotherapeutic1R41AI129106-01 · under PA-15-270RAM, SANJAYWYCOFF, KEITHPLANET BIOTECHNOLOGY, INC., CA$242,093ZRG1
2017Novel HDAC Inhibitors for Treatment of Hemoglobinopathies1R41HL136068-01 · under PA-15-270PERRINE, SUSAN PARKWILLIAMS, ROBERT MICHAELCETYA THERAPEUTICS, INC., CO$241,742ZRG1
2017Developing a new therapeutic agent for retinal ciliopathies1R41EY027667-01 · under PA-15-270KATSANIS, NICHOLASRESCINDO THERAPEUTICS, INC., NC$238,837ZRG1
2017Develop technology platform to transform the diagnosing, monitoring and treating of opioid use disorders1R41DA044905-01SCHMIDLE, PATRIKCARI HEALTH, INC., CA$235,848ZRG1
2017Next generation quantitative HCV drug resistance assay1R43DK112540-01A1WAGNER, RICHARDWANG, GARY P.MEDOSOME BIOTEC, LLC, FL$232,433ZRG1
2017Roboglasses® electronic travel aid with hands free obstacle avoidance for blind and vision impaired users1R41EY027623-01A1GIUDICE, NICHOLAS ASKIBA, JEFFRYFAUXSEE INNOVATIONS, LLC, AR$226,023ZRG1
2017A novel product for tendinopathy treatment1R41AG056246-01A1SUN, HUI BINNEW YORK/R&D/CTR/TRANSLATIONAL MED/THER, NY$225,042ZRG1
2017Novel Small Molecule Macrophage Inhibitors for the Treatment of Retinal Diseases1R41EY027219-01 · under PA-15-270COUSINS, SCOTT WILLIAMEYEDESIS BIOSCIENCES, LLC, NC$225,030ZRG1
2017Testing and Commercialization of a Superior Device to Maintain Perioperative Normothermia In Anesthetized Patients.1R41GM119871-01A1 · under PA-15-270DILLER, KENNETH R.MERCURY BIOMED, LLC, OH$225,000ZRG1
2017Oligonucleotide Inhibition for cardiac regeneration in Ischemia1R41HL134387-01A1BRAR, BHAWANJIT KJAAN BIOTHERAPEUTICS, INC., CA$225,000ZRG1
2017Epigenetic Markers and Sustained Cytoprotection for Stroke Treatment1R41NS098918-01A1BOOHER, KEITHGUO, WEIHUANG, SHAOLINGZYMO RESEARCH CORPORATION, CA$225,000ZRG1
2017Hit-to-Lead optimization of small-molecule inhibitors of herpes simplex viruses1R41AI131739-01MORRISON, LYNDA A.ROGERS, BRUCE LEECASTERBRIDGE PHARMACEUTICALS, INC., MA$225,000ZRG1
2017Personalized Neural Stem Cell Therapy for Cancer1R41TR001789-01A1NICHOLS, SUSANFALCON THERAPEUTICS, INC., NC$225,000ZRG1
2017Novel methods to improve nuclease mediated homologous recombination1R41GM122181-01A1ZHANG, JIFENGATGC, INC., MI$225,000ZRG1
2017Investigation of antibody-drug conjugates of a novel target1R41CA213479-01A1CUI, JIELIU, QINGYUNWNTRIX, INC., TX$225,000ZRG1
2017A Novel Scaffold to Promote Skin Regeneration1R41AR070681-01A1LEVINSON, HOWARDXEQUEL BIO, INC., SC$225,000ZRG1
2017Novel Reagents for Breast Tumor SPECT Imaging1R41CA217546-01LEVIN, MICHAEL DAVIDCAVATAR, LLC, CA$225,000ZRG1
2017Developing a novel therapy for diabetic retinopathy1R41EY027665-01A1LI, WEITIAN, HONGEVERGLADES BIOPHARMA, LLC, TX$225,000ZRG1
2017E-training of Inmate Peer Caregivers for Enhancing Geriatric and End-of-life Care in Prisons1R41AG057239-01LOEB, SUSAN JAYNEKLEIN BUENDEL, INC., CO$225,000ZRG1
2017Neuro-Optical Diagnostic System for Macular Degeneration1R41AG057250-01SRIDHAR, SRINIVASNEUROFIELDZ, INC., MA$225,000ZRG1
2017Skin Microbiome Editing with Fermentation Initiator1R41AR070676-01A1HUANG, CHUN-MINGSURFACE BIOADVANCES, INC., CA$225,000ZRG1
2017Therapeutic game-based exercise during hemodialysis to improve balance and mobility1R41AG057743-01A1NAJAFI, BIJANBIOSENSICS, LLC, MA$225,000ZRG1
2017Persistent-mode, Liquid-helium-free, Robust Bi2212 Magnets for MRI and >1GHz NMR1R43EB025109-01OTTO, ALEXANDERSOLID MATERIAL SOLUTIONS, LLC, MA$225,000ZRG1
2017Direct magnetic characterization of individual nanoparticles for optimized diagnostic imaging1R41MH115884-01ACOSTA, VICTOR MARCELJARMOLA, ANDREJSODMR TECHNOLOGIES, INC., CA$225,000ZRG1
2017MISSION U: A Multimedia Training Tool for Treating Individuals with Co-occurring Mental Health and Substance Use Disorders1R41AA026751-01A1SMELSON, DAVID APRAXIS, INC., MA$225,000ZRG1
2017Developing an automated yeast dissection system for aging research1R41AG058368-01DANG, WEIWEIJO, MYEONG CHANINNOVATIVE BIOCHIPS, LLC, TX$225,000ZRG1
2017Noom Coach for Bariatric Surgery1R44DK116370-01HILDEBRANDT, THOMAS BMICHAELIDES, ANDREASNOOM, INC., NY$225,000ZRG1
2017Drug-eluting Brachytherapy Implants for Chemo-radiation Therapy1R41CA224646-01SRIDHAR, SRINIVASTHERANANO, LLC, MA$225,000ZRG1
2017Dihydroceramide Desaturase-1 Inhibitors for Treatment of Diabetes and Other Metabolic Diseases1R43DK116450-01BLITZER, JEREMYSUMMERS, SCOTT APOTRERO HILL THERAPEUTICS, INC., CA$225,000ZRG1
2017Development of Environmental Health Education Games1R41ES027731-01A1JONES, PAULETTE THURLEYMEADOWLARK SCIENCE AND EDUCATION, LLC, MT$224,999ZRG1
2017Therapeutic disruption of Connexin43-mediated microtubule regulation to target glioblastoma cancer stem cells1R41CA217503-01LAMOUILLE, SAMYACOMHAL RESEARCH, INC., VA$224,999ZRG1
2017Small-molecule therapy for metastatic prostate cancer1R41CA217491-01A1WU, DAQINGMETCURE THERAPEUTICS, LLC, GA$224,999ZRG1
2017Artificial neural networks for high performance, fully automated particle tracking analysis even at low signal-to-noise regimes1R41GM123897-01LAI, SAMUELAI TRACKING SOLUTIONS, LLC, NC$224,997ZRG1
2017Preparation of site-specific antibody-drug conjugates by proximity-based sortase ligation1R41CA221374-01TSOURKAS, ANDREWALPHATHERA, INC., PA$224,996ZRG1
2017An integrative multi-phenotype pipeline for drug evaluation, pharmacogenomics, and attribute prediction1R41TR001908-01 · under PA-15-270JAEGER, PHILIPPPHENVOGEN, LLC, CA$224,991ZRG1
2017Lead Compound Discovery from Engineered Analogs of Occidiofungin1R41AI131792-01SMITH, JAMES LEIFSANO CHEMICALS, INC, TX$224,939ZRG1
2017Polo-box PLK1 Inhibitors Target Tumors Resistant to ATP Competitive Compounds1R41CA213711-01A1MCINNES, CAMPBELLPPI PHARMACEUTICALS, LLC, SC$224,933ZRG1
2017Virtual-reality games to assess and habilitate auditory spatial awareness1R41DC016578-01ZOTKIN, DMITRYVISISONICS CORPORATION, MD$224,924ZRG1
2017A cloud-based software platform to enhance reproducibility, collaboration and translation of stem cell research1R41GM125489-01TUBON, THOMAS CCELLARA, LLC, WI$224,909ZRG1
2017Structure-based optimization of a novel pharmacological chaperone therapy for MPSIIIC1R41HD092110-01CHANG, GEOFFREY ASINGAMSETTY, SRIKANTHPHOENIX NEST, INC., NY$224,873ZRG1
2017Soluble E-NTPDase for sepsis1R41GM120838-01A1 · under PA-15-270HASKO, GEORGEPURINE PHARMACEUTICALS, INC., NJ$224,871ZRG1
2017Integrated tools for higher order structure determination by cross-link analysis1R41GM122169-01A1UEBERHEIDE, BEATRIX MAGDALENAPROTEIN METRICS, LLC, CA$224,870ZRG1
2017Hyperphosphorylated tau aggregation kit to identify tauopathy risk factor1R41AG057274-01BOCHAR, DANIELCAYMAN CHEMICAL COMPANY, INC., MI$224,852ZRG1
2017A Novel Hernia Mesh to Improve Anchor Point Fixation and Prevent Hernia Formation1R41GM117657-01A1RUPPERT, DAVIDDEEP BLUE MEDICAL ADVANCES, INC., NC$224,837ZRG1
2017Mitochondrial Targeted Nano-antioxidants to Treat Alzheimer's Disease1R41AG055254-01A1PAUTLER, ROBIA GACELEROX, LLC, TX$224,813ZRG1
2017Using Technology to Optimize Child Mental Health Care In Real World Settings1R41MH114716-01WHITESIDE, STEPHENMINNESOTA HEALTHSOLUTIONS CORPORATION, MN$224,744ZRG1
2017Develop a new cisplatin-based drug combination with reduced ototoxicity1R41DC016575-01BAO, JIANXINGATEWAY BIOTECHNOLOGY, INC., MO$224,700ZRG1
2017Developing a Nutraceutical Product against Noise-Induce Hearing Loss1R41DC016842-01BAO, JIANXINGATEWAY BIOTECHNOLOGY, INC., MO$224,700ZRG1
2017Development of a New Carbohydrate-based Anticoagulant Drug1R41HL139187-01LIU, JIANGLYCAN THERAPEUTICS CORPORATION, NC$224,698ZRG1
2017Bioimpedance-based Intracranial Mapping for Monitoring Evolving TBI1R41NS100313-01 · under PA-15-270HALTER, RYAN JOSEPHRYTEK MEDICAL, INC., NH$224,609ZRG1
2017Targeting Synaptotagmin-2 to Prevent Airway Mucus Obstruction1R41HL136057-01 · under PA-15-270DICKEY, BURTON FVARADHACHARY, ATULEXOTECT, LLC, TX$224,576ZRG1
2017Tools for site-specific antibody immobilization for immunoassays1R41EB023750-01 · under PA-15-270TSOURKAS, ANDREWALPHATHERA, INC., PA$224,556ZRG1
2017SA-FasL-engineered human islets as a novel product for the treatment of type 1 diabetes1R41DK111314-01A1YOLCU, ESMA SFASCURE THERAPEUTICS, LLC, KY$224,529ZRG1
2017Lipid Enhanced Nano-Sensors (LENS) for lead and mercury detection in water1R41ES028643-01LENHERT, STEVENZANSORS, LLC, VA$224,528ZRG1
2017Microparticulate mucosal vaccine for triple-negative breast cancer1R41CA206652-01A1 · under PA-15-270CHIRIVA-INTERNATI, MAURIZIOMIRANDOLA, LEONARDOKIROMIC, INC., TX$224,522ZRG1
2017Biomimetic Wound Healing Devices to Close Diabetic Wounds1R41DK112416-01A1ENSLEY, BURT DEWITTPROTEIN GENOMICS, INC., AZ$224,503ZRG1
2017Online Training For Addressing Perinatal Depression1R41MH113381-01BYATT, NANCYPRAXIS, INC., MA$224,465ZRG1
2017TheraBracelet: The first and only wearable to instantly improve stroke hand function1R41HD090792-01A1SEO, NA JINTHERABRACELET, INC., KY$224,256ZRG1
2017Creation of animal models of mitochondrial DNA disease for translational research applications1R41GM125577-01RUIZ, JOSEPH C.ENZERNA BIOSCIENCES, LLC, NC$224,093ZRG1
2017Development of CaSR nutrient therapy for childhood diarrhea1R41HD092133-01CHENG, SAM XMEDOSOME BIOTEC, LLC, FL$223,899ZRG1
2017Telehealth Intervention for Improved Blood Pressure Control with Targeted Incentives: Using New Technologies and Insights From Behavioral Economics to Increase the Effectiveness of Behavioral Change1R41AG056184-01GNEEZY, URIWELLTH, INC., NY$223,743ZRG1
2017Automated Electrophysiology Assessment of Drug-induced Cardiotoxicity Based on Parallel, Noninvasive Nanoelectrode Array1R41EB022439-01A1 · under PA-15-270JIANG, XINCYION TECHNOLOGIES, LLC, CA$223,028ZRG1
2017Biodegradable gold nanoparticles as contrast agents for CT1R41EB023169-01A1CORMODE, DAVID PETERPOLYAURUM, LLC, PA$223,028ZRG1
2017Leveraging Health Information Technology to Improve School-Based Mental Health1R41MH112230-01A1FAGAN, COREYMENTAL HEALTH DATA SERVICES, INC., WA$222,784ZRG1
2017A Transparent Surgical Mask to Improve Patient/Caregiver Communication, Minimize Errors and Increase Patient Satisfaction1R41NR017124-01HAHNE, JEANNEFACEVIEW MASK, LLC, OR$222,317ZRG1
2017Preclinical Development of a Novel Small Molecule Drug for Sepsis1R41GM123858-01BRENNER, MAXWANG, HAICHAOTHERASOURCE, LLC, NY$222,172ZRG1
2017Application of PPODA-QT for embolization of aneurysms1R41NS097069-01A1 · under PA-15-270BECKER, TIMANEUVAS TECHNOLOGIES, INC., AZ$220,109ZRG1
2017AML-MutationCounter, a tool to detect residual and recurrent leukemia1R41CA213690-01 · under PA-15-270KAUFMANN, WILLIAM K.ASYSTBIO LABORATORIES, LLC, NC$220,087ZRG1
2017Therapeutic Mabs for Chronic Kidney Disease1R41DK112426-01 · under PA-15-270LUKACS, NICHOLAS WOPSIDIO, LLC, PA$217,446ZRG1

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