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NIH funding notice PAR-14-088

Direct Phase II SBIR Grants to Support Biomedical Technology Development

Closed on January 7, 2017.

Posted
February 5, 2014
Close date
January 7, 2017
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

248 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $213,177,248 in first-year total cost, median $774,443.

Most frequent study sections

  1. Special Emphasis Panel[ZRG1 ETTN-M (11)]21
  2. Special Emphasis Panel[ZRG1 SBIB-T (10)]17
  3. Special Emphasis Panel[ZRG1 CVRS-C (10)]14
  4. Special Emphasis Panel[ZRG1 IDM-X (10)]12
  5. Special Emphasis Panel[ZRG1 ETTN-C (10)]9

Most frequent institutions

  1. BIOSENSICS, LLC4
  2. FOX CHASE CHEMICAL DIVERSITY CENTER, INC3
  3. RADIKAL THERAPEUTICS, INC.3
  4. ADVANCED BRAIN MONITORING, INC.2
  5. ALDATU BIOSCIENCES, INC.2
Competing awards under PAR-14-088 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2017A Novel Device for Optimal and Personalized Fluid Therapy in Septic Shock Patients1R44GM123799-01BURNETT, DANIEL ROGERSCONNOR, MICHAEL JOSEPHJUNCOS, LUIS A.POTRERO MEDICAL, INC., CA$1,685,221ZRG1
2017Eliminating Ventricular Tachycardia: First in Human Clinical Trial using the Durablate™ Catheter1R44HL132746-01A1CURLEY, MICHAEL GTHERMEDICAL, INC., MA$1,673,144ZRG1
2017Ultrasound Enhanced Low Dose Drug Delivery: Quantifying Uptake, Retention and Biodistribution1R44HL139241-01KILROY, JOSEPH P.SOUNDPIPE, LLC, VA$1,588,126ZRG1
2017Advanced therapeutic for Parkinson's Disease1R44NS103695-01WERNER, MILTON H.INHIBIKASE THERAPEUTICS, GA$1,554,020ZRG1
2017Wearable Sensors for Quantitative Assessment of Motor Impairment in Huntington's Disease1R44NS103648-01GWIN, JOSEPH TBIOSENSICS, LLC, MA$1,314,945ZRG1
2017Discovering a Disease Modifying Therapeutic to Treat Huntington's Disease1R44AG059272-01A1SIPPOLA-THIELE, MARIA SIRPACHAPERONE THERAPEUTICS, INC., NC$1,300,009ZRG1
2017A robust kit, standards, and software for identifying RNA binding protein targets1R44HG009875-01SHISHKIN, ALEXANDER AECLIPSE BIOINNOVATIONS INC, CA$1,278,018ZRG1
2017Development of New Improved Perflutren Ultrasound Contrast Agent1R44HL137447-01A1PORTER, THOMAS RUNGER, WYATT DANIELMICROVASCULAR THERAPEUTICS, LLC, AZ$1,229,385ZRG1
2017Validation of targets for therapeutic intervention in NASH1R44DK115301-01WAMHOFF, BRIAN ROBERTHEMOSHEAR THERAPEUTICS, LLC, VA$1,211,258ZRG1
2017AVGN7, a Novel Gene Therapeutic for Treating Cancer Cachexia1R44CA221539-01RODGERS, BUELAAVOGEN, INC., MD$1,206,955ZRG1
2017IND-enabling development of a biomimetic peptide drug for macular edema1R44EY027632-01PANDEY, NIRANJAN BASCLEPIX THERAPEUTICS, INC., MD$1,165,695ZRG1
2017BiVACOR Rotary Total Artificial Heart1R44HL137454-01A1TIMMS, DANIELBIVACOR, INC., TX$1,158,587ZRG1
2017Standardization of a Fluidic In Vitro Exposure System for IVIVE Predictive Toxicity Data1R44GM123796-01MCCLELLAND, RANDALL EDWINMOSEDALE, MERRIESCIKON INNOVATION, INC., NC$1,085,817ZRG1
2017An Oral Ultra Long-Acting Ivermectin for Malaria Elimination1R44TR001889-01A1BELLINGER, ANDREW MARTINLYNDRA THERAPEUTICS, INC., MA$1,047,601ZRG1
2017Monitoring immune response to immunotherapies in cancer patients with VisAcT PET tracer1R44CA221624-01GOTH, SAMUEL RAYLEVI, JELENACELLSIGHT TECHNOLOGIES, INC., CA$1,020,143ZRG1
2017A phase IIA trial for the safety and tolerability of CD24Fc in prophylaxis of graft vs host disease.1R44CA221513-01DEVENPORT, MARTINDEVINE, STEVEN M.REDDY, PAVANONCOIMMUNE, INC., MD$1,017,478ZRG1
2017Predicting DILI liability by transcription factor profiling1R44GM125469-01MAKAROV, SERGEI SATTAGENE, INC., NC$1,016,149ZRG1
2017Combining faster detection with ID: a new paradigm for mycobacterial culture1R44AI128777-01RHODES, PAULSPECIFIC DIAGNOSTICS, INC., CA$1,000,000ZRG1
2017Development of methionyl-tRNA synthetase inhibitors for Gram positive bacterial infections1R44AI134190-01LIPKA, ELKETSRL, INC., MI$1,000,000ZRG1
2017A Phase 2 clinical trial of topical uracil for the prevention of capecitabine induced hand-foot syndrome1R44CA213519-01ISAACMAN, STEVENROWINKSY, ERIC KNANOMETICS, LLC, CA$999,914ZRG1
2017Development of Chemistry, Manufacturing, and Control Standards for PGC and PGC-dANP1R44HL134448-01A1CASTILLO, GERARDO M.PHARMAIN CORPORATION, WA$999,661ZRG1
2017Development of an H2O2-inactivated chikungunya virus vaccine1R44AI128990-01AMANNA, IAN JAMESSLIFKA, MARK KNAJIT TECHNOLOGIES, INC., OR$999,652ZRG1
2017Clinical Development of JS-K for the Treatment of Cancer1R44CA221570-01NOWOSLAWSKI, JOSEPH FELIXJSK THERAPEUTICS, INC., UT$999,183ZRG1
2017Development of GIFT4: a B cell focused immunotherapy for cancer1R44CA217365-01GUYRE, PAULCELDARA MEDICAL, LLC, NH$999,088ZRG1
2017Immune Deficient Mosquitoes for Improved Malaria Sporozoite Vaccine Manufacture1R44AI131806-01A1BILLINGSLEY, PETER F.SANARIA, INC., MD$998,817ZRG1
2017Rapid Low Cost Phenotypic Antibiotic Susceptibility Testing.1R44AI131963-01RHODES, PAULSPECIFIC DIAGNOSTICS, INC., CA$998,141ZRG1
2017PANDAA for rapid genotyping of HIV-1 infected patients failing protease inhibitor ART in resource-limited settings1R44AI128974-01MACLEOD, IAIN JAMESALDATU BIOSCIENCES, INC., MA$998,024ZRG1
2017Advancing a novel potent Zika virus specific nucleoside analog to the clinic1R44AI129024-01A1KLUMPP, KLAUSRIBOSCIENCE, LLC, CA$993,605ZRG1
2017ZW800-1: The 1st Zwitterionic NIR Fluorophore for Cancer Imaging & Ureter Mapping1R44CA210820-01A1FRANGIONI, JOHN VCURADEL, LLC, MA$989,401ZRG1
2017Preclinical development of PPCM vaginal contraceptive to submit IND.1R44HD092206-01NORTH, BARBARA BESTOLDHAM, MICHAEL JWALLER, DONALD PWEITZEL, MARY BYASO THERAPEUTICS INC, TX$985,250ZRG1
2017Commercialization of low cost, disposable, point-of-care molecular diagnostic device for sexually transmitted infections1R44AI134565-01LONEY, GREGORY CVISBY MEDICAL, INC., CA$980,734ZRG1
2017Development of two simple and robust point-of-care assays for detection and therapy monitoring of hepatitis B in resource-limited settings1R44AI132034-01A1LEE, HELEN HDIAGNOSTICS FOR THE REAL WORLD, LTD, CA$968,003ZRG1
2017Monitoring and Stabilizing Behavioral Rhythms to Improve Mental Health1R44MH113520-01FRANK, ELLENHEALTH RHYTHMS, INC., NY$964,251ZRG1
2017A robust platform for high-throughput single-cell genetic variation analysis1R44HG009465-01A1EASTBURN, DENNIS JMISSION BIO, INC., CA$951,385ZRG1
2017Novel MRI Contrast Agent for Detection of Beta Amyloid1R44AG051292-01A1WORKING, PETERALZECA BIOSCIENCES, INC., TX$942,582ZRG1
2017A rapid, culture-free whole genome approach for characterizing complex metagenomics samples1R44GM123907-01PUTNAM, NICHOLAS HELMSDOVETAIL GENOMICS, LLC, CA$938,049ZRG1
2017Glycosaminoglycan-Interacting Small Molecule (GISMO) as Alzheimer's Therapeutics1R44AG056231-01A1GREGOR, PAULGISMO THERAPEUTICS, INC., NY$933,415ZRG1
2017RetiVue DR, a point and shoot, non-mydriatic, widefield retinal camera for diabetic eye screening1R44EY028484-01LAI, MINGNETLAND, PETER AOSANAI, YOJIRETIVUE, VA$926,693ZRG1
2017A New Filter Paper Technology for Flavivirus Collection, Shipping, and Analysis1R44AI132032-01HOGAN, MICHAEL E.LANGENBACH, KURT JOHNNASARABADI, SHANAVAZGENTEGRA, LLC, CA$909,182ZRG1
2017Tailored Drug Titration through Artificial Intelligence1R44HL132622-01A1VOSKERICIAN, GABRIELAOPTIMA INTEGRATED HEALTH, INC., CA$849,047ZRG1
2017A Single-Cell Device to Detect Pathogenic Cell Populations in Bone Marrow Disease1R44EB023777-01A1MCCONNELL, TIMOTHY SZHOU, JINGISOPLEXIS, INC., DE$845,621ZRG1
2017Long-acting ghrelin for the treatment of cancer cachexia1R44CA213844-01SOLIMAN, TARIKEXTEND BIOSCIENCES, INC., MA$832,924ZRG1
2017Magnetic Duodeno-Ileal Bypass for Metabolic Syndrome in Rhesus Monkeys1R44DK112453-01A1HARRISON, MICHAEL RMAGNAMOSIS, INC., CA$829,853ZRG1
2017Retinal tissue derived from human pluripotent stem cells for vision restoration1R44EY027654-01A1NASONKIN, IGOR O.PETERSEN-JONES, SIMONSEILER, MAGDALENE JBIOTIME, INC., CA$816,848ZRG1
2017Broadly neutralizing(BN) pan-IgE supersite vaccine for allergic asthma1R44AI126680-01A1CHEN, SWEY-SHENIGE THERAPEUTICS, INC., CA$813,544ZRG1
2017Implementing an innovative suite of mobile applications for depression and anxiety.1R44MH114725-01NAIK, SMIT VADAPTIVE HEALTH, INC., IL$810,676ZRG1
2017Monoclonal Sandwich ELISA for Serum Erythroferrone for Clinical Assessment of Ineffective Erythropoiesis1R44DK113841-01OSTLAND, VAUGHN EINTRINSIC LIFESCIENCES, LLC, CA$810,487ZRG1
2017Suction Device for Control and Accuracy of Transseptal Access1R44HL135937-01A1KASSAB, GHASSAN SMANSFIELD, GEORGE A3DT HOLDINGS, LLC, CA$808,638ZRG1
2017Rapid detection of minimal residual disease in acute myeloid leukemia from peripheral blood1R44CA213595-01MULLER, ROLFBIOFLUIDICA, INC, CA$798,225ZRG1
2017Development of a nanoemulsion-adjuvanted prophylactic HSV-2 vaccine1R44AI126964-01A1FATTOM, ALI I.BLUEWILLOW BIOLOGICS, INC., MI$798,081ZRG1
2017Stream Dx: accurate and efficient, point-of-care uroflometry for improved diagnosis, monitoring, and post-treatment evaluation of LUTS1R44DK113878-01HOTALING, JAMESMCCLELLAN, SCOTT BRADFORDSTREAM DX, INC., UT$798,054ZRG1
2017Optimization and Pre-Clinical Studies of a Protein Therapeutic for Recruiting Brown Adipocytes1R44DK113877-01A1BOSS, OLIVIERENERGESIS PHARMACEUTICALS, INC., MA$793,958ZRG1
2017Development of Novel Targeted Chemotherapeutics for the Treatment ofMalignant Pleural Mesothelioma1R44CA221543-01SORGI, FRANK LFLAG THERAPEUTICS, INC., NC$787,067ZRG1
2017RehabTouch: A mixed-reality gym for rehabilitating the hands, arms, trunk, and legs after stroke1R44AG059256-01A1ROWE, JUSTINFLINT REHABILITATION DEVICES, CA$775,488ZRG1
2017Development of the PTP1B inhibitor MSI-1436 for therapeutic stimulation of heart regeneration following acute myocardial infarction1R44HL139161-01YIN, VIRAVUTH PREVIDIA THERAPEUTICS, INC, ME$769,681ZRG1
2017Rapid, Near Patient Nucleic Acid Testing for Congenital Cytomegalovirus (CMV) Infection1R44DC016576-01NORTON, SCOTT MICHAELBAEBIES, INC., NC$763,182ZRG1
2017Personalized precision dosing of biologic therapies in oncology1R44CA217336-01A1MESSMER, BRADLEY TABREOS BIOSCIENCES, INC., CA$759,813ZRG1
2017Individualized Signal Processing Strategy :Phase II1R44DC016249-01KRAUSE, LEE STANLEYSECURBORATION, INC., FL$758,924ZRG1
2017Mouthpiece for mTBI Detection during Adolescent Contact and Collision Sports1R44HD090763-01A1HEDIN, DANIEL SADVANCED MEDICAL ELECTRONICS CORPORATION, MN$756,497ZRG1
2017Pre-clinical Commercialization of a Synthetically Designed, Live-attenuated RSV Vaccine1R44AI131756-01MUELLER, STEFFENCODAGENIX, INC., NY$755,377ZRG1
2017Exploratory Clinical Study to Evaluate the Potential Bioactivity of CLBS14 in Patients with Coronary Microvascular Dysfunction1R44HL135889-01LOSORDO, DOUGLAS WLISATA THERAPEUTICS INC, NJ$753,565ZRG1
2017Developing a novel antifungal targeting Gwt1 for the treatment of invasive aspergillosis and rare mold infections1R44AI131864-01A1SHAW, KAREN JOYSTEINBACH, WILLIAM JAMPLYX PHARMACEUTICALS, INC., CA$750,293ZRG1
2017Phase 3 Study of SGX301 and Fluorescent Light for Cutaneous T Cell Lymphoma1R44CA210848-01A1STRAUBE, RICHARD CONRADSOLIGENIX, INC., NJ$750,000ZRG1
2017Clinical resting state fMRI software for surgical planning1R44GM125438-01OLSEN, TIMOTHYRADIOLOGICS, INC., MO$749,900ZRG1
2017Regulatory Validation of Standardized Clinical Laboratory Immunohistochemistry Controls1R44CA213476-01BOGEN, STEVEN ABOSTON CELL STANDARDS INC, MA$749,890ZRG1
2017Complete genome de novo assembly software for the emerging long read sequencing era1R44GM122120-01DURFEE, TIMOTHY JDNASTAR, INC., WI$749,795ZRG1
2017Bifunctional K-ATP channel opener and redox catalyst for treatment of hemorrhagic shock1R44GM122095-01SOUTHAN, GARRY JOHNRADIKAL THERAPEUTICS, INC., MA$749,330ZRG1
2017PET Imaging Agents for the in vivo Detection of TDP-431R44AG059278-01REITZ, ALLEN BERNARDFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$745,412ZRG1
2017HLS-Highly-Sensitive, One-minute, Portable Diagnostic for Malaria Elimination1R44AI131810-01GALEN, PETERHEMEX HEALTH, INC., OR$740,558ZRG1
2017Development of a TRPA1 Antagonist Opioid-Sparing Analgesic for Chronic Pain1R44DA044900-01HERZ, JEFF MARKALGOMEDIX, INC., WA$734,315ZRG1
2017ExoSOUND: An Acoustofluidic Device for Exosome Isolation1R44GM125439-01WANG, LINASCENT BIO-NANO TECHNOLOGIES, INC., NC$730,899ZRG1
2017A Hand-Held Robot to Cure BPH1R44EB024423-01A1HENDRICK, RICHARD JOSEPHVIRTUOSO SURGICAL, INC., TN$726,587ZRG1
2017Improved Electrode Material for High-Density Closed-Loop DBS.1R44NS103714-01PETROSSIANS, ARTINPLATINUM GROUP COATINGS, LLC, CA$725,814ZRG1
2017Exosomal Drug Delivery1R44CA221487-01GUPTA, RAMESH CSPENCER, WENDY A3P BIOTECHNOLOGIES, INC., KY$719,680ZRG1
2017Low-Cost Instrument-free Point-of-Care Diagnostic for Neisseria gonorrhoeae1R44AI129031-01DEAN, DEBORAH ANNEMITRA, DEBKISHORELUCIRA HEALTH, INC, CA$716,689ZRG1
2017Evaluation of a Robotic Assisted Surgical System for Hearing Loss1R44DC016246-01HENSLEE, ALLANIOTAMOTION, INC., MN$709,641ZRG1
2017Tools for Accelerating R&D for Historically Understudied Protein Kinases1R44TR001916-01ZUTSHI, REENALUCEOME BIOTECHNOLOGIES, LLC, AZ$708,631ZRG1
2017Rapid saliva test for diagnostics of Neuro-Cognitive Disorder due to Traumatic Brain Injury (NCDT)1R44HD090817-01A1GRIFFIN, TIMOTHY J.PEACOCK, WILLIAM FRANKLINPUCCIO, AVA M.SOUTHERN, SARKA OLIVERAGAIA MEDICAL INSTITUTE, INC., CA$708,335ZRG1
2017Handheld ultrasound system for real-time thoracic epidural analgesia guidance1R44GM123791-01MAULDIN, FRANK WILLIAMRIVANNA MEDICAL, INC., VA$704,777ZRG1
2017Cartilage Regeneration with Tunable Inflammation Resistance1R44AG059310-01ESTES, BRADLEY TCYTEX THERAPEUTICS INC., NC$704,742ZRG1
2017Membrane-based vaccine with checkpoint blockade for triple negative breast cancer1R44CA221559-01KANNAN, KAMAL V.PACK, CHRISTOPHER DMETACLIPSE THERAPEUTICS CORPORATION, GA$700,539ZRG1
2017Non-obtrusive tissue manipulation device for treatment of carpal tunnel syndrome1R44EB024713-01SON, JAE S.PRESSURE PROFILE SYSTEMS, INC., CA$683,645ZRG1
2017Development of Novel Adenosine Polymers for Coating Medical Devices1R44HL136233-01A1FORMAN, MERVYN B.ADENOPAINT, LLC, GA$683,627ZRG1
2017Development of Oral Small Molecule PCSK9 Antagonist1R44HL137449-01ELSHOURBAGY, NABIL AMOUSA, SHAKER ASHIFA BIOMEDICAL CORPORATION, PA$682,343ZRG1
2017Development of a Miniature Mass Spectromtry System for Point-of-Care Applications1R44GM119584-01OUYANG, ZHENGPURSPEC TECHNOLOGIES, INC., IN$672,527ZRG1
2017Orally-Bioavailable Peroxynitrite Decomposition Catalyst Targeting Post-Surgical Pain1R44DA044893-01DAX, SCOTT LCERSCI THERAPEUTICS, INC., TX$658,085ZRG1
2017A Novel Topical HSP90 Inhibitor (CTXT-102) in the Treatment of Mild to Moderate Plaque Psoriasis1R44AR071174-01A1GREK, CHRISTINAREGRANION, LLC, SC$654,034ZRG1
2017Independent Exoskeleton-Use through Robust Stand-to-Sit Safety1R44AG057267-01BECKER, ADAMINNOVATIVE DESIGN LABS, INC., MN$653,843ZRG1
2017Spring System for Permanent Relief of Urinary Obstruction related to Benign Prostatic Hyperplasia1R44DK112587-01A1DAMIANO, NICHOLASZENFLOW, INC., CA$636,601ZRG1
2017Reversing Isoniazid Resistance By Isotopic Substitution1R44AI129005-01A1TIMMINS, GRAHAM SSPINCEUTICA, INC., NM$586,360ZRG1
2017A Novel Device for Ultra-Rapid Non-Pharmacologic Ocular Anesthesia1R44EY028495-01CHALBERG, THOMAS WIRENIX MEDICAL, INC., CA$581,104ZRG1
2017A Novel Gyrase Inhibitor for the Treatment of Drug-susceptible and Multidrug-resistant Mycobacterium tuberculosis Infections1R44AI131749-01PUCCI, MICHAEL JSPERO THERAPEUTICS, INC., MA$564,718ZRG1
2017Characterizing Alzheimer's Disease with INSPECDS: Integrated Neurocognitive and Sleep-Behavior Profiler for the Endophenotypic Classification of Dementia Subtypes1R44AG054256-01A1BERKA, CHRISADVANCED BRAIN MONITORING, INC., CA$538,507ZRG1
2017Automated Objective Audiometry using Long Latency Steady State Responses1R44DC015920-01A1DELGADO, RAFAEL EINTELLIGENT HEARING SYSTEMS, FL$508,257ZRG1
2017Treatment of type 1 diabetes with human embryonic stem cell derived pancreatic beta-like cells1R44DK115257-01D'AMOUR, KEVINVIACYTE, INC., CA$500,370ZRG1
2017Preclinical Validation of Novel High Affinity D2 Receptor Agonists for PET Neuroimaging1R44OD024615-01NEUMEYER, JOHN LNATURAL PHARMACIA INTERNATIONAL, INC., MA$499,999ZRG1
2017Liquid CO2 Flash Chromatography System1R44GM122107-01A1SCHLAKE, ROLFAPPLIED SEPARATIONS, INC., PA$492,238ZRG1
2017Development of NSI-189, a novel neurogenic molecule, to prevent and treat diabetic neuropathy1R44NS103703-01JOHE, KARL KNEURALSTEM, INC., MD$491,049ZRG1
2017Enrichment-free Salmonella detection for food safety1R44AI134498-01KOERIS, MICHAEL SANDORSAMPLE6 TECHNOLOGIES, INC., MA$489,513ZRG1
2017In vitro and in vivo efficacy of liposomal ciprofloxacin formulations against Mycobacterium avium and Mycobacterium abscessus1R44AI134572-01BERMUDEZ, LUIZ EDUARDOBLANCHARD, JAMES DARADIGM CORPORATION, CA$486,599ZRG1
2017Self-Digitization Microfluidic Platform for Digital PCR1R44GM123797-01KREUTZ, JASON EUGENELAMPROGEN, INC., WA$469,045ZRG1
2017New Treatment of the Brain in Niemann Pick C1R44NS098877-01A1PARDRIDGE, WILLIAM MLIPOGENE COMPANY, INC., CA$460,967ZRG1
2017Web Software to develop an RDoC-Compatible Adaptive Diagnostic Nosology, the SID-51R44MH108177-01A1BRODEY, BENJAMIN BTELESAGE, INC., NC$433,630ZRG1
2017An integrated transcriptomic and proteomic approach to antibody sequencing and repertoire characterization1R44GM122102-01CASTELLANA, NATALIEDIGITAL PROTEOMICS LLC, CA$388,404ZRG1
2017Portable Hearing Laboratory1R44DC016247-01A1PAVLOVIC, CASLAV VOJISLAVBATANDCAT, INC., CA$374,226ZRG1
2016BPN14770 Safety and Cognitive Effect in Young and Elderly Subjects1R44AG054243-01GURNEY, MARK ETETRA DISCOVERY PARTNERS, INC., MI$2,055,899ZRG1
2016Development of a novel drug treatment for decompensated heart failure.1R44HL131086-01A1MAHAN, LAWRENCEMADELEINE PHARMACEUTICALS, INC., WI$1,996,767ZRG1
2016Mobility Life: Monitoring Mobility in Daily Lives of People with Neurological Disease1R44AG055388-01EL-GOHARY, MAHMOUDHORAK, FAY BAHLINGAPDM, INC., OR$1,805,525ZRG1
2016A new reference panel to boost African American genotype imputation1R44HG009460-01AUTON, ADAM23ANDME, INC., CA$1,758,557ZRG1
2016Improved Dosing and Refinement of a Cardiac Targeted Gene Therapy in a Swine Infarct Model1R44HL129782-01A1TEICHMAN, SAMBEAT BIOTHERAPEUTICS CORPORATION, WA$1,545,537ZRG1
2016Cyanalyzer A Medical Laboratory Device for the Rapid Diagnosis of Cyanide Exposure1R44NS097066-01A1HOBSON, STEPHEN TERRENCESEACOAST SCIENCE, INC., CA$1,343,682ZRG1
2016Validation of a non-invasive technology to measure bilirubin in newborns1R44HD090778-01CLARKE, MICHAEL STEPHENBILICAM, LLC, WA$1,297,065ZRG1
2016Highly Accelerated Simultaneous Multi-Slice Phase Contrast MRI1R44MH112210-01A1FEINBERG, DAVID ALANADVANCED MRI TECHNOLOGY, LLC, CA$1,287,772ZRG1
2016sHLA Protein Chip for Anti-HLA Antibody Screening and Monitoring1R44AI122642-01HOGAN, MICHAEL E.GENOMICS USA, INC., TX$1,281,226ZRG1
2016Therapeutic antibody for RSV1R44AI122360-01KAUVAR, LAWRENCE MICHAELTRELLIS BIOSCIENCE, INC., CA$1,268,751ZRG1
2016A Novel Pharmacological Treatment for Neuropathic Pain1R44NS100173-01MOSKAL, JOSEPHAPTINYX, INC., IL$1,249,376ZRG1
2016Advanced Human on a Chip Systems for Drug Discovery1R44TR001326-01A1HICKMAN, JAMES JSHULER, MICHAEL LHESPEROS, LLC, FL$1,241,321ZRG1
2016Real-time histopathology for intra-operative tumor margin delineation1R44CA206664-01FREUDIGER, CHRISTIANORRINGER, DANIELINVENIO IMAGING INC., CA$1,218,888ZRG1
2016Bactericidal antibiotic for Vancomycin Resistant Enterococci1R44AI122426-01A1LAFLEUR, MICHAELARIETIS, MA$1,218,307ZRG1
2016Development of novel inhibitors of C1q for the treatment of Neurodegenerative diseases1R44AG054404-01SANKARANARAYANAN, SETHUYEDNOCK, TEDANNEXON, INC., CA$1,213,915ZRG1
2016Advancement to Clinical Candidate of Novel, Potent and Selective Chikungunya virus inhibitor series1R44AI122421-01PEVEAR, DANIEL CVENATORX PHARMACEUTICALS, INC., PA$1,139,136ZRG1
2016Development of an LXR agonist as first in class therapy for treatment of metastatic melanoma1R44CA206677-01A1KURTH, ISABELRGENIX, INC., NY$1,117,983ZRG1
2016An Active Hemostatic Clamping Device for Bloodless Surgery and Trauma1R44GM114934-01A1MITCHELL, STUART BNOVUSON SURGICAL, INC., WA$1,076,073ZRG1
2016Portable iridium-electrode inhaled Nitric Oxide generator for treatment of lung diseases1R44TR001704-01SILKOFF, PHILIP ETHIRD POLE, INC., MA$1,073,276ZRG1
2016Validation of a rapid point-of-care breath test for breast cancer1R44CA203019-01A1PHILLIPS, MICHAELMENSSANA RESEARCH, INC., NJ$1,071,867ZRG1
2016Development of Intrasaccular Flow Disrupters for Small and Ruptured Aneurysms1R44NS097038-01KALLMES, DAVID FPATTERSON, WILLIAM ROBERTSEQUENT MEDICAL, INC., CA$1,051,119ZRG1
2016A prospective, multi-center pivotal study of the LUM Imaging System for real-time, in vivo margin assessment in breast conserving surgery1R44CA211013-01LEE, W. DAVIDLUMICELL, INC., MA$1,033,123ZRG1
2016Colon cancer risk-stratification via optical analysis of rectal ultrastructure1R44CA199667-01A1NGUYEN, THE-QUYENWALI, RAMESH KAMERICAN BIOOPTICS, LLC, IL$1,030,462ZRG1
2016A NOVEL NEUROPROTECTIVE THERAPY FOR ALZHEIMER’S DISEASE1R44AG053084-01ABRAHAM, CARMELAABRAHAM, MENACHEMWINDISCH, MANFREDKLOGENE THERAPEUTICS, INC., MA$1,022,134ZRG1
2016Technology to Select Candidates for Prophylactic Treatments to Prevent Sporadic Breast Cancers1R44CA206774-01A1POOLA, INDIRA NONESILBIOTECH, INC., MD$1,009,044ZRG1
2016DEVELOPMENT OF TOPICAL ANTIVIRAL AGENTS FOR TREATING MOLLUSCUM CONTAGIOSUM1R44AI125005-01SCOTT, RICHARD WFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$1,002,030ZRG1
2016A glycolipid adjuvant to promote dose sparing, accelerate immunization schedules and extend durability of high-level protection with a live attenuated sporozoite malaria vaccine1R44AI125009-01HOFFMAN, STEPHEN LEVSANARIA, INC., MD$1,000,000ZRG1
2016A Phase I Dose-escalation Study of Intraperitoneal CYN101 as Consolidation Immunotherapy in Women with Residual or Recurrent Ovarian Cancer Status after Chemotherapy1R44CA206606-01MERUELO, DANIELWINRAM, SCOTT BUDDCYNVEC, LLC, NY$995,814ZRG1
2016An Integrated Device for Rapid Bacteremia Diagnosis from Whole Blood1R44AI124726-01SINGER, ALONHELIXBIND, INC., MA$985,030ZRG1
2016HBI-002 to Treat Delayed Graft Function in Kidney Transplant1R44DK111260-01GOMPERTS, EDWARDOTTERBEIN, LEO EHILLHURST BIOPHARMACEUTICALS, INC., CA$862,618ZRG1
2016Novel peptide-coated suture for cleft lip and palate repair1R44DE026080-01SOO, CHIAZHENG, ZHONGSCARLESS LABORATORIES, INC., CA$860,274ZRG1
2016CTL for supertype natural IgE cytotoxic peptide (nECP) to guard against allergic asthma1R44AI122358-01CHEN, SWEY-SHENIGE THERAPEUTICS, INC., CA$853,476ZRG1
2016Development of protein therapeutic for acute kidney injury1R44DK112403-01TAN, TAOTRIM-EDICINE, INC., OH$833,693ZRG1
2016Innovative Image-Guided Device for Beating Heart Mitral Valve Repair1R44HL131101-01WILSON, PETER MCKEAGEHARPOON MEDICAL, INC., MD$830,130ZRG1
2016Magnetic Mini Mover Device for the Treatment of Pectus Excavatum1R44HL134520-01HARRISON, MICHAEL RMAGNETS-IN-ME, LLC, CA$825,332ZRG1
2016Establishing In Vivo Proof of Concept of Brown Adipogenesis Using Approved Drugs1R44DK109860-01BOSS, OLIVIERENERGESIS PHARMACEUTICALS, INC., MA$812,187ZRG1
2016WayToServe Español: A Culturally-Appropriate Online Responsible Beverage Service Training for Spanish-Speaking Servers1R44MD010405-01A1WOODALL, W GILLKLEIN BUENDEL, INC., CO$798,184ZRG1
2016Wearable Patch Reader for Peripheral Artery Disease1R44HL134532-01WISNIEWSKI, NATALIE ANNPROFUSA, INC., CA$787,161ZRG1
2016High-Resolution Magnetoencephalography using Atomic Magnetrodes1R44MH110288-01ALEM, ORANGQUSPIN, CO$772,932ZRG1
2016Buccal Nanocytological Risk Stratification to Personalize Lung Cancer Screening1R44CA206844-01A1SUBRAMANIAN, HARIHARANNANOCYTOMICS, LLC, IL$769,969ZRG1
2016Development of novel isoflavone drugs as broad spectrum antivirals1R44AI115824-01A1BEDARD, KRISTIN MGALE, MICHAELKINETA, INC., WA$757,817ZRG1
2016Production of therapeutic human polyclonal antibodies against influenza viruses1R44AI117976-01A1HUBER, VICTOR CHESTERJIAO, JINANSAB BIOTHERAPEUTICS, INC., SD$756,080ZRG1
2016Iridium-electrode inhaled Nitric Oxide generator for treatment of hypoxic respiratory failure in neonates1R44HL134429-01SILKOFF, PHILIP ETHIRD POLE, INC., MA$754,483ZRG1
2016Improving vaccine development through high-throughput immunogenicity screening.1R44AI127039-01BROOKS, BENJAMIN DELBERTCOHEN, GARY HEISENBERG, ROSELYN JMYSZKA, DAVID G.CARTERRA, INC., UT$751,913ZRG1
2016Recombinant Hyperimmune Gammaglobulin for Primary Immunodeficiency1R44AI124901-01JOHNSON, DAVID SCOTTGIGAGEN, INC., CA$750,198ZRG1
2016Fracture Risk Assessment Software for Skeletal Metastasis1R44AR069421-01GWIN, JOSEPH TBIOSENSICS, LLC, MA$750,000ZRG1
2016A pro-resolution lipid mediator for treatment of rheumatoid arthritis1R44AR070686-01JAGTAP, PRAKASH GRADIKAL THERAPEUTICS, INC., MA$750,000ZRG1
2016Tau Oligomer Platform Validation Using Lead Series Candidate in htau Mice1R44AG053150-01MOE, JAMES G.OLIGOMERIX, INC, NY$749,795ZRG1
2016Development and testing of MRI-mediated radiofrequency ablation system and probes1R44CA203276-01A1ACKERMAN, JEROME LNEVO, EREZROBIN MEDICAL, INC., MD$749,066ZRG1
2016Development of a non-addictive analgesic targeting opioid receptor heteromers.1R44DA041912-01YEKKIRALA, AJAY SBLUE THERAPEUTICS, INC., MA$746,689ZRG1
2016Exploratory Chemistry on a new antibiotic1R44AI122425-01A1HUGHES, DALLASNOVOBIOTIC PHARMACEUTICALS, LLC, MA$746,210ZRG1
2016Prevention of Syncope with GSN Stimulation1R44HL132656-01A1LEVIN, HOWARDCORIDEA, LLC, NY$740,435ZRG1
2016Development of a novel quadrivalent seasonal influenza vaccine using E.coli production technology1R44AI125168-01A1LI, SHENGQIANGSCIOGEN, LLC, CA$737,500ZRG1
2016Assessment of Bioreactor-Derived Human Platelet Quality, Storage Profile, Safety, and Function1R44HL131050-01KARLSSON, SVEN MSTELLULAR BIO, INC., MA$729,375ZRG1
2016Developing a Novel, Fungicidal Therapeutic to Treat Coccidioidomycosis1R44AI125017-01SHAW, KAREN JOYAMPLYX PHARMACEUTICALS, INC., CA$728,595ZRG1
2016Innovating Tablet-Based Cognitive Assessment for CNS Disorders of Aging1R44AG053121-01KEEFE, RICHARD SVERASCI, LLC, NC$711,254ZRG1
2016Integrated Neurocognitive and Sleep-Behavior Profiler for the Endophenotypic Classification of Dementia Subtypes (INSPECDS)1R44AG050326-01A1BERKA, CHRISADVANCED BRAIN MONITORING, INC., CA$710,663ZRG1
2016Allosteric MIF Inhibitors for Rheumatoid Arthritis Therapy1R44AR067569-01A1ANTHONY, KAREN G.CIRILLO, PIER FRANCESCOL2 DIAGNOSTICS, LLC, CT$694,516ZRG1
2016Internally Calibrated Chromatin Immunoprecipitation Using Barcoded Nucleosomes1R44HG008907-01SUN, ZU-WENEPICYPHER, INC., NC$676,616ZRG1
20162-Hydroxybenzylamine for the prevention of Alzheimer's disease: Initial evaluation in humans1R44AG055184-01RATHMACHER, JOHN AMETABOLIC TECHNOLOGIES, INC., IA$672,479ZRG1
2016An interactive, wearable device for measuring and motivating hand use after stroke1R44HD086953-01FRIEDMAN, NIZANFLINT REHABILITATION DEVICES, CA$658,518MRS
2016An HIV Viral Load Assay for the Point-Of-Care1R44AI124964-01A1FERNANDEZ-SUAREZ, MARTAOYUGI, JULIUS OTIENODAKTARI DIAGNOSTICS, INC., MA$649,571ZRG1
2016Novel Androgen Receptor Degraders to Treat Castration-Resistant Prostate Cancer1R44CA203199-01TAYLOR, IANARVINAS, INC., CT$648,400ZRG1
2016I Live Inspired: Individually Tailored and Integrated Social Support Network for Tobacco Cessation1R44DA041904-01DEUTSCH, CHRISTOPHERLIVE INSPIRED, LLC, DC$642,136ZRG1
2016A Quantitative Epigenetic Test for Guiding Smoking Cessation Therapy1R44CA213507-01PHILIBERT, ROBERT ABD HOLDING, INC., IA$642,097ZRG1
2016Large animal study on deeply porous transcutaneous pylon for direct skeletal attachment1R44HD090768-01PITKIN, MARKPOLY-ORTH INTERNATIONAL, MA$621,050ZRG1
2016Predictive tool to prevent overdose in patients treated with prescription opioids1R44DA042655-01SASINOWSKI, MACIEKVENEBIO GROUP, LLC, VA$607,585ZRG1
2016Development of a Telehealth Platform for Treatment with the SpeechVive Device1R44DC014867-01A1HUBER, JESSICA ELAMBERT, ASHLEIGHSPEECHVIVE, INC., IN$597,381ZRG1
2016Sustained release gel enabling one-stage treatment of prosthetic joint infection1R44AR070685-01OVERSTREET, DEREK JAMESVERNON, BRENT LSONORAN BIOSCIENCES, INC., AZ$564,985ZRG1
2016New Test System for Blood Lead Levels in Children1R44HD087097-01BONAVENTURA, CELIA JHENKENS, ROBERT WALDERON BIOSCIENCES, INC., NC$554,446ZRG1
2016Platform for practical delivery of oral autoantigens as co-therapies for neurological disease1R44NS098830-01PILLER, KENNETH JSOYMEDS, INC., NC$548,420ZRG1
2016SMALL MOLECULE THERAPY FOR ALZHEIMER'S DISEASE1R44AG050336-01SUNDARAM, PAZHANIRECOMBINANT TECHNOLOGIES, LLC, CT$519,209ZRG1
2016LASER TISSUE WELDING: BREACHING BARRIERS IN THE SURGICAL MANAGEMENT OF THE PANCREAS1R44CA203052-01BARAKAT, OMARWADIA, YASMINLASER TISSUE WELDING, INC., TX$500,000ZRG1
2016Brain DNA Therapeutics with Trojan Horse Liposomes1R44NS097040-01A1PARDRIDGE, WILLIAM MLIPOGENE COMPANY, INC., CA$499,613ZRG1
2016Development of Rodent Self-Administration Vapor Inhalation Chambers for THC1R44DA041967-01COLE, MAURY D.LA JOLLA ALCOHOL RESEARCH, INC., CA$499,190ZRG1
2016Superficially Porous Silica Based Chiral Stationary Phases for High Efficiency and High Speed Pharmaceutical Analysis and Purification1R44GM117783-01LEE, JAUH TZUOHAZYP, LLC, TX$486,100ZRG1
2016A Quantitative Systems Pharmacology Software Platform for Biologics: reduce costs and accelerate development of innovative biotherapeutics1R44GM116214-01A1APGAR, JOSHUAAPPLIED BIOMATH, LLC, MA$469,938ZRG1
2016A high volume parallel acoustic flow cytometer for the detection of rare cells or particles in a large sample volume with a low background concentration (i.e. very dilute samples).1R44GM117649-01GRAVES, STEVEN WETA DIAGNOSTICS, INC., NM$468,750ZRG1
2016Hemodynamic Noninvasive Skin Cancer Diagnostics1R44CA203038-01A1CHACHISVILIS, MIRIANASVERISKIN, INC., CA$455,835ZRG1
2016Mutant transgenic plant cells as a novel source of drugs1R44AA025804-01LITTLETON, JOHN M.NAPROGENIX, INC, KY$455,773ZRG1
2015Overcoming the last barrier to commercialization of virus-specific T cell therapy1R44AI118693-01A1WILSON, JOHNWILSON WOLF MANUFACTURING CORPORATION, MN$1,599,561ZRG1
2015A kit for massively parallel single cell gene expression analysis1R44HG008323-01FAN, CHRISTINACELLULAR RESEARCH, INC., CA$1,512,400ZRG1
2015Treatment of congenital heart disease associated pulmonary hypertension1R44HD082865-01SALZMAN, ANDREW LURIERADIKAL THERAPEUTICS, INC., MA$1,500,000ZRG1
2015CATHEPSIN L INHIBITORS AS PAN-CORONAVIRUS THERAPEUTICS1R44AI118063-01GREENBAUM, DORONPHELIX THERAPEUTICS, LLC, PA$1,475,511ZRG1
2015A new class of non-opioid analgesics for use in chronic pain management1R44DA038968-01A1BUNKER, KEVIN DKALYRA PHARMACEUTICALS, INC., CA$1,242,938ZRG1
2015Anticoagulum Cardiac RF Ablation Catheter (Direct Phase II)1R44HL127758-01SIGG, DANIELFOCUSSTART, LLC, MN$1,220,224ZRG1
2015Cross-Protective Multivalent Vaccine for Tick-Borne Flaviviruses1R44AI118017-01CLEMENTS, DAVID EHAWAII BIOTECH, INC., HI$1,156,549ZRG1
2015Optimization and Validation of an Indicator Cell Assay for Blood-Based Diagnosis of Alzheimers Disease1R44AG051282-01SMITH, JENNIFER JOYPRECYTE, INC., MD$1,151,844ZRG1
2015First-in-Class Macrocyclic Peptide Therapeutic For Rheumatoid Arthritis1R44AR068833-01TRAN, DAT QUANGORYN THERAPEUTICS, LLC, CA$1,142,534ZRG1
2015Clinical Evaluation of T3D-959 as a Potential Disease Remedial Therapeutic for the Treatment of Alzheimer's Disease1R44AG049510-01DE LA MONTE, SUZANNE M.DIDSBURY, JOHNT3D THERAPEUTICS, INC., NC$1,127,955ZRG1
2015Development of a DIVI platform for issue resolution in pre-clinical drug development.1R44GM113304-01A1WAMHOFF, BRIAN ROBERTHEMOSHEAR THERAPEUTICS, LLC, VA$1,126,395ZRG1
2015Development of Small Molecule Therapeutics Against Smallpox and Other Poxviruses1R44AI115759-01SCOTT, RICHARD WFOX CHASE CHEMICAL DIVERSITY CENTER, INC, PA$1,110,810ZRG1
2015A Phase IIa Study of rHuIL-12 as an Immunotherapy and Radiomitigator for CTCL Patients Receiving Radiotherapy1R44CA192576-01BASILE, LENA A.NEUMEDICINES, INC., CA$1,088,333ZRG1
2015Clinical Evaluation of a Novel Prostate Cancer PET Diagnostic1R44CA192451-01LANGTON-WEBSTER, BEATRICECANCER TARGETED TECHNOLOGY, LLC, WA$1,076,087ZRG1
2015Oxygen Mapping System for Enhanced Colonoscopic Neoplasm Detection1R44CA192460-01ZAND, JASON MATTHEWSURGISENSE CORPORATION, MD$1,072,220ZRG1

Showing the 200 most recent of 248 awards.

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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