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NIH funding notice PAR-15-071

Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Pharmacodynamics and In vivo Efficacy Studies for Small Molecules and Biologics/Biotechnology Products (R21/R33)

Closed on April 19, 2018.

Posted
December 12, 2014
Close date
April 19, 2018
Activity codes
R21, R33
Institutes taking part
NINDS, NIDA

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

Its page names no earlier notice: it is new, or it does not say.

Replaced by PAR-18-761.

Who won it before

19 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $6,931,064 in first-year total cost, median $369,304.

Most frequent study sections

  1. Neurological Sciences and Disorders A Study Section[NSD-A]11
  2. Neurological Sciences and Disorders B Study Section[NSD-B]7
  3. Neurological Sciences and Disorders C Study Section[NSD-C]1

Most frequent institutions

  1. EMORY UNIVERSITY2
  2. OREGON HEALTH & SCIENCE UNIVERSITY2
  3. UNIVERSITY OF MIAMI SCHOOL OF MEDICINE2
  4. UNIVERSITY OF PITTSBURGH AT PITTSBURGH2
  5. INDIANA UNIVERSITY INDIANAPOLIS1
Competing awards under PAR-15-071 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2018Development and validation of small molecules to treat neurofibromatosis associated schwannoma1R21NS105941-01BANNISTER, THOMAS DKISSIL, JOSEPHSCRIPPS FLORIDA, FL$475,000NSD
2018EP2 antagonists as novel anti-epileptogenic agents1R21NS101167-01A1GANESH, THOTAEMORY UNIVERSITY, GA$403,718NSD
2018Use of CRISPR/Cas9 to treat Huntington disease1R21NS106120-01WARREN, STEPHEN T.EMORY UNIVERSITY, GA$390,000NSD
2018DMF for intracerebral hemorrhage1R21NS104460-01ARONOWSKI, JAROSLAWSAVITZ, SEAN IUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$385,000NSD
2018Reversal of preexisting neuropathic pain by spinal delivery of AIBP1R21NS104769-01A1MILLER, YURYYAKSH, TONY L.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$380,298NSD
201820-HETE Formation Inhibitors in Cardiac Arrest1R21NS107785-01MCDERMOTT, LEE APOLOYAC, SAMUEL MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$369,304NSD
2018Pharmacodynamics and in vivo efficacy of fumarate for mitochondrial disease in vivo1R21NS106719-01A1CORTOPASSI, GINO AUNIVERSITY OF CALIFORNIA AT DAVIS, CA$367,706NSD
2018Exploring Antisense Oligonucleotides as a potential therapy for Autosomal Dominant Leukodystrophy1R21NS104384-01A1PADIATH, QUASAR SUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$353,208NSD
2018Long Acting Local Analgesics: HSV-CA8 Biotherapeutics1R21NS105880-01LEVITT, ROY C.UNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$329,297NSD
2018Gene Therapy Knockdown and Replacement of GARS to Treat Dominant Inherited Peripheral Neuropathy1R21NS105116-01A1BURGESS, ROBERT W.HARPER, SCOTT QJACKSON LABORATORY, ME$290,309NSD
2017In vivo efficacy studies to support the development of DUX4-targeted RNAi therapy for FSHD1R21NS101166-01HARPER, SCOTT QRESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH$389,002NSD
2017Neural Stem Cell Carriers for Glioblastoma Immunotherapy1R21NS101150-01BALYASNIKOVA, IRINA VNORTHWESTERN UNIVERSITY AT CHICAGO, IL$388,890NSD
2017Complement inhibitors targeted to the ischemic brain for the treatment of stroke1R21NS097653-01A1TOMLINSON, STEPHENMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$345,320NSD
2016Global RNA Interference Therapy for Huntingtons Disease1R21NS095245-01A1MCBRIDE, JODI L.OREGON HEALTH & SCIENCE UNIVERSITY, OR$437,500NSD
2016Optimization of Compounds that Stabilize the SMN Protein for Treatment of SMA1R21NS095139-01ANDROPHY, ELLIOT J.HODGETTS, KEVINLORSON, CHRISTIAN L.INDIANA UNIVERSITY INDIANAPOLIS, IN$431,954NSD
2016Efficacies and Pharmacodynamic Assays for LRRK2 Small-Molecule Inhibitors1R21NS097643-01WEST, ANDREW BUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$367,500NSD
2016Red blood cell microparticles (RMPs) to reduce bleeding following hemorrhagic stroke1R21NS094896-01DAVE, KUNJAN RUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$307,000NSD
2016Modified neural stem cells for glycosylation-independent treatment of MPS IIIB1R21NS096044-01IACOVINO, MICHELINALUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER, CA$260,587NSD
2016Development of Poly ICLC for neuroprotection against ischemic brain injury1R21NS094833-01A1STENZEL-POORE, MARY POREGON HEALTH & SCIENCE UNIVERSITY, OR$259,471NSD

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAR-15-071: Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Pharmacodynamics and In vivo Efficacy Studies for Small Molecules and Biologics/Biotechnology Products (R21/R33) | ScienceDex | ConductScience