The notices it replaced
- Reissues: PAR-13-254 NIAID Investigator Initiated Program Project Applications (P01)
- 2 steps back: PAR-10-271 NIAID Investigator Initiated Program Project Applications (P01)
Replaced by PAR-20-072.
Who won it before
78 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $164,973,374 in first-year total cost, median $2,109,990.
Most frequent study sections
- Special Emphasis Panel[ZAI1 JA-I (M1)]5
- Special Emphasis Panel[ZAI1 GEB-I (M1)]4
- Special Emphasis Panel[ZAI1 ZL-I (M1)]3
- Special Emphasis Panel[ZAI1 BDP-I (M2)]2
- Special Emphasis Panel[ZAI1 BLG-M (M1)]2
Most frequent institutions
- HARVARD MEDICAL SCHOOL4
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH4
- COLUMBIA UNIVERSITY HEALTH SCIENCES3
- DUKE UNIVERSITY3
- FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH3
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2020 | Anti NMDA Receptor antibodes in adult brain dysfunction and fetal brain development: lessons from lupus2P01AI073693-11A1 | DIAMOND, BETTY | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, NY | $2,883,980 | ZAI1 |
| 2020 | Pathway Analysis in Tuberculosis1P01AI143575-01A1 | EHRT, SABINE | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $2,639,702 | ZAI1 |
| 2020 | Protective immunity following dengue virus natural infections and vaccination2P01AI106695-06 | HARRIS, EVA | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $2,579,906 | ZAI1 |
| 2020 | Dynamics of Colonization and Infection by Multidrug-resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)1P01AI152999-01 | ARIAS, CESAR AUGUSTOSAVIDGE, TOR C.SHELBURNE, SAMUEL A | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $2,463,657 | ZAI1 |
| 2020 | Biology and structure of pMHC receptors functioning as mechanosensors in the [alpha][beta] T-cell lineage1P01AI143565-01A1 | LANG, MATTHEW J.REINHERZ, ELLIS L | DANA-FARBER CANCER INST, MA | $2,444,290 | ZAI1 |
| 2020 | Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity2P01AI108545-06 | VIGNALI, DARIO AA | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $2,353,012 | ZAI1 |
| 2020 | Mechanisms controlling distinct growth and functional characteristics of the perinatal and adult thymus1P01AI139449-01A1 | RICHIE, ELLEN R | UNIVERSITY OF TX MD ANDERSON CAN CTR, TX | $2,326,438 | ZAI1 |
| 2020 | Inherited T cell defects: Diagnosis, Mechanisms and Treatments1P01AI138962-01A1 | MARSON, ALEXANDERPUCK, JENNIFER M. | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $2,217,974 | ZAI1 |
| 2020 | Mechanisms of Norovirus Pathogenesis and Replication to Develop Therapeutics2P01AI057788-16 | ATMAR, ROBERT L.ESTES, MARY KOLBPRASAD, BIDADI VENKATARAM | BAYLOR COLLEGE OF MEDICINE, TX | $2,174,478 | ZAI1 |
| 2020 | Transcription factor regulation of CD4 and CD8 T cell effector and memory differentiation and function1P01AI145815-01A1 | CROTTY, SHANE P | LA JOLLA INSTITUTE FOR IMMUNOLOGY, CA | $2,057,042 | ZAI1 |
| 2020 | Inflammasome and Gasdermin Signaling Networks for Regulation of Pyroptosis and Cytokine Release1P01AI141350-01A1 | DUBYAK, GEORGE R | CASE WESTERN RESERVE UNIVERSITY, OH | $1,886,706 | ZAI1 |
| 2020 | Pathways Regulating Lung Transplant Tolerance.2P01AI116501-06 | KREISEL, DANIEL | WASHINGTON UNIVERSITY, MO | $1,600,284 | ZAI1 |
| 2020 | Lymph nodes at the crossroads of allo immunity and regulation1P01AI153003-01 | ABDI, REZA | BRIGHAM AND WOMEN'S HOSPITAL, MA | $1,289,295 | ZAI1 |
| 2019 | Immunologic and virologic determinants of congenital Cytomegalovirus transmission and disease in rhesus monkeys1P01AI129859-01A1 | BARRY, PETER APERMAR, SALLIE R. | DUKE UNIVERSITY, NC | $2,863,852 | ZAI1 |
| 2019 | Microbiota and Allergic Asthma Precision Prevention (MAAP2)2P01AI089473-06 | JOHNSON, CHRISTINE COWNBY, DENNIS R | HENRY FORD HEALTH SYSTEM, MI | $2,859,652 | ZAI1 |
| 2019 | T Cell Costimulatory Pathways: Functions and Interactions2P01AI056299-16 | SHARPE, ARLENE H. | HARVARD MEDICAL SCHOOL, MA | $2,582,651 | ZAI1 |
| 2019 | Tissue Regulation of T Cell Function2P01AI102851-06 | FOWELL, DEBORAH J | UNIVERSITY OF ROCHESTER, NY | $2,434,774 | ZAI1 |
| 2019 | Staphylococcal Biofilm and Disease2P01AI083211-11 | BAYLES, KENNETH W. | UNIVERSITY OF NEBRASKA MEDICAL CENTER, NE | $2,358,655 | ZAI1 |
| 2019 | Mechanisms of peripheral induction of T-cell tolerance2P01AI035296-25A1 | HOGQUIST, KRISTIN A. | UNIVERSITY OF MINNESOTA, MN | $2,173,652 | ZAI1 |
| 2019 | VIral and host mechanisms that tilt the HSV lytic/latent balance2P01AI098681-06A1 | COEN, DONALD MKNIPE, DAVID M. | HARVARD MEDICAL SCHOOL, MA | $2,164,748 | ZAI1 |
| 2019 | Molecular basis of γδ T lineage specification2P01AI102853-06 | WIEST, DAVID L. | RESEARCH INST OF FOX CHASE CAN CTR, PA | $2,144,459 | ZAI1 |
| 2019 | Chronic Rhinosinusitis Integrative Studies Program 2 (CRISP2)1P01AI145818-01 | SCHLEIMER, ROBERT P | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $1,933,411 | ZAI1 |
| 2018 | Tissue compartmentalization of human lymphocytes2P01AI106697-06 | FARBER, DONNA L. | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $2,958,301 | ZAI1 |
| 2018 | Structure-based Discovery of Critical Vulnerabilities of Mycobacteria2P01AI095208-05A1 | SACCHETTINI, JAMES C | TEXAS A&M AGRILIFE RESEARCH, TX | $2,542,664 | ZAI1 |
| 2018 | Zika virus pathophysiology during pregnancy1P01AI132132-01A1 | O'CONNOR, DAVID H. | UNIVERSITY OF WISCONSIN-MADISON, WI | $2,100,487 | ZAI1 |
| 2018 | Molecular Determinants of Tissue-resident Memory T cell Fate in Acute and Chronic Infection1P01AI132122-01A1 | GOLDRATH, ANANDA W | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $1,988,765 | ZAI1 |
| 2018 | Role of TIM Molecules in Regulatory and Inflammatory B cells in Allo andAutoimmunity1P01AI129880-01A1 | ROTHSTEIN, DAVID M | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $1,913,055 | ZAI1 |
| 2018 | Flavivirus Infections: Pathogenesis and Prevention2P01AI034533-26 | ROTHMAN, ALAN L | UNIVERSITY OF RHODE ISLAND, RI | $1,900,000 | ZAI1 |
| 2018 | Toward a Universal Influenza Virus Vaccine2P01AI097092-06A1 | PALESE, PETER | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $1,802,510 | ZAI1 |
| 2018 | Epithelial innate signaling in airway inflammation and remodeling2P01AI062885-11 | GAROFALO, ROBERTO P | UNIVERSITY OF TEXAS MED BR GALVESTON, TX | $1,767,677 | ZAI1 |
| 2018 | Tick Immune Signaling, Microbiota, and Acquisition of Borrelia burgdorferi and Anaplasma phagocytophilum1P01AI138949-01 | FIKRIG, EROLPAL, UTPALPEDRA, JOAO | UNIV OF MARYLAND, COLLEGE PARK, MD | $1,578,353 | ZAI1 |
| 2018 | Immune Function and the Progression to Type 1 Diabetes2P01AI042288-20 | ATKINSON, MARK A. | UNIVERSITY OF FLORIDA, FL | $1,366,867 | ZAI1 |
| 2018 | Epitope-focused vaccine strategies against Zika virus1P01AI138938-01 | NUSSENZWEIG, MICHEL C | ROCKEFELLER UNIVERSITY, NY | $1,365,131 | ZAI1 |
| 2017 | A Tolerance Approach to Xenotransplantation2P01AI045897-17 | SACHS, DAVID HSYKES, MEGAN | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $3,166,671 | ZAI1 |
| 2017 | Costimulatory Mechanisms of Autoimmunity2P01AI039671-20A1 | HAFLER, DAVID A. | YALE UNIVERSITY, CT | $2,654,197 | ZAI1 |
| 2017 | Structure-function analysis of infection- and vaccine-induced B-cell repertoires2P01AI089618-06 · under PAR-13-254 | HARRISON, STEPHEN COPLAN | BOSTON CHILDREN'S HOSPITAL, MA | $2,637,545 | ZAI1 |
| 2017 | Harnessing the power of experimental genetic crosses and systems genetics to probe drug resistance in malaria1P01AI127338-01A1 | FERDIG, MICHAEL T | UNIVERSITY OF NOTRE DAME, IN | $2,408,349 | ZAI1 |
| 2017 | Systems Genetics of Tuberculosis1P01AI132130-01 | SASSETTI, CHRISTOPHER M | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $2,300,000 | ZAI1 |
| 2017 | Cellular and Molecular Defects in Human B Cell Development2P01AI061093-13A1 | CUNNINGHAM-RUNDLES, CHARLOTTE | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY | $2,181,897 | ZAI1 |
| 2017 | Human Cytomegalovirus dysregulation of host hematopoietic progenitor cell signaling pathways to modulate latency, reactivation, and hematopoiesis during transplantation1P01AI127335-01 · under PAR-13-254 | NELSON, JAY AYUROCHKO, ANDREW D | OREGON HEALTH & SCIENCE UNIVERSITY, OR | $2,000,000 | ZAI1 |
| 2017 | Innate-Adaptive Immunoregulation in Liver Transplant Ischemia/Reperfusion Injury1P01AI120944-01A1 | KUPIEC-WEGLINSKI, JERZY W | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $1,685,815 | ZAI1 |
| 2017 | Infections and the Stability of Transplantation Tolerance2P01AI097113-06 | ALEGRE, MARIA-LUISA | UNIVERSITY OF CHICAGO, IL | $1,587,600 | ZAI1 |
| 2017 | PPG: SARS-CoV-host cell interactions and vaccine development2P01AI060699-11 · under PAR-13-254 | PERLMAN, STANLEY | UNIVERSITY OF IOWA, IA | $1,280,579 | ZAI1 |
| 2016 | Bridging Antibody Fc-mediated Antiviral Functions Across Humans and Non-human Primates1P01AI120756-01A1 · under PAR-13-254 | TOMARAS, GEORGIA DORIS | DUKE UNIVERSITY, NC | $3,264,079 | ZAI1 |
| 2016 | Durable Antibody Mediated Protection Against HIV1P01AI124912-01 · under PAR-13-254 | GALLO, ROBERT C | UNIVERSITY OF MARYLAND BALTIMORE, MD | $3,215,425 | ZAI1 |
| 2016 | Structural and Functional Characterization of the Ebola Virus Replication Complex1P01AI120943-01A1 · under PAR-13-254 | AMARASINGHE, GAYA K. | WASHINGTON UNIVERSITY, MO | $2,876,287 | ZAI1 |
| 2016 | A Tolerance Approach to Xenotransplantation2P01AI045897-16 · under PAR-13-254 | SACHS, DAVID HSYKES, MEGAN | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $2,745,913 | ZAI1 |
| 2016 | Optimizing Combination Therapy to Accelerate Clinical Cure of Tuberculosis1P01AI123036-01 · under PAR-13-254 | DRUSANO, GEORGE LOUISLOUIE, ARNOLD | UNIVERSITY OF FLORIDA, FL | $2,336,318 | ZAI1 |
| 2016 | Pathogenesis, Transmission and Detection of Zoonotic Prion Diseases2P01AI077774-06A1 · under PAR-13-254 | SOTO, CLAUDIO | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $2,243,704 | ZAI1 |
| 2016 | Intracellular pathogens and innate immunity2P01AI063302-13 · under PAR-13-254 | PORTNOY, DANIEL A | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $2,135,624 | ZAI1 |
| 2016 | Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR2P01AI091580-06 · under PAR-13-254 | WEISS, ARTHUR | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $2,113,290 | ZAI1 |
| 2016 | Plasma Cells in Health and Disease1P01AI125180-01 · under PAR-13-254 | SANZ, IGNACIO E. | EMORY UNIVERSITY, GA | $2,084,461 | ZAI1 |
| 2016 | Mechanisms of Kidney-Induced Cardiac Allograft Tolerance1P01AI123086-01 · under PAR-13-254 | MADSEN, JOREN C | MASSACHUSETTS GENERAL HOSPITAL, MA | $2,076,389 | ZAI1 |
| 2016 | Harvard-wide Program on Antibiotic Resistance2P01AI083214-09 · under PAR-13-254 | GILMORE, MICHAEL S | MASSACHUSETTS EYE AND EAR INFIRMARY, MA | $2,061,148 | ZAI1 |
| 2016 | Resolving the bottleneck in antibiotic discovery1P01AI118687-01A1 · under PAR-13-254 | LEWIS, KIM | NORTHEASTERN UNIVERSITY, MA | $1,857,306 | ZAI1 |
| 2016 | Targeting Immunogenicity to the MPER Hinge and C-helix for BNAb Elicitation1P01AI126901-01 · under PAR-13-254 | REINHERZ, ELLIS L | DANA-FARBER CANCER INST, MA | $1,760,661 | ZAI1 |
| 2016 | Disruption of T cell tolerance in type 1 diabetes1P01AI118688-01A1 · under PAR-13-254 | ANDERSON, MARK S | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $1,691,347 | ZAI1 |
| 2016 | Pathogenesis of E. coli and Shigella infections in human enteroid models1P01AI125181-01 · under PAR-13-254 | DONOWITZ, MARKKAPER, JAMES BNATARO, JAMES P. | UNIVERSITY OF MARYLAND BALTIMORE, MD | $1,633,930 | ZAI1 |
| 2015 | Integrating Mechanistic Insights from Diverse Models to Prevent CMV Reactivation following Transplantation1P01AI112522-01A1 · under PAR-13-254 | ABECASSIS, MICHAEL M | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $2,305,939 | ZAI1 |
| 2015 | Synergies among inhibitory receptors in tolerance, cancer and antiviral immunity1P01AI108545-01A1 · under PAR-13-254 | VIGNALI, DARIO AA | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $2,223,392 | ZAI1 |
| 2015 | Protective immunity following dengue virus natural infections and vaccination1P01AI106695-01A1 · under PAR-13-254 | HARRIS, EVA | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $2,106,690 | ZAI1 |
| 2015 | Transdisciplinary Program to Identify Novel Antifungal Targets and Inhibitors1P01AI104533-01A1 · under PAR-13-254 | PERFECT, JOHN R. | DUKE UNIVERSITY, NC | $1,877,844 | ZAI1 |
| 2015 | TIM family of genes: Role in T cell immunity and tolerance2P01AI073748-06A1 · under PAR-13-254 | KUCHROO, VIJAY K. | BRIGHAM AND WOMEN'S HOSPITAL, MA | $1,873,527 | ZAI1 |
| 2015 | Antibody-Mediated Rejection of Renal Allografts2P01AI087586-06 · under PAR-13-254 | FAIRCHILD, ROBERT L | CLEVELAND CLINIC LERNER COM-CWRU, OH | $1,815,591 | ZAI1 |
| 2015 | Molecular Dissection of Norovirus Replication and Pathogenesis to Develop Therapeutics2P01AI057788-11 · under PAR-13-254 | ESTES, MARY KOLB | BAYLOR COLLEGE OF MEDICINE, TX | $1,795,078 | ZAI1 |
| 2015 | Immune Airway-Epithelial Interactions in Steroid-Refractory Severe Asthma1P01AI106684-01A1 · under PAR-13-254 | RAY, ANURADHAWENZEL, SALLY E | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $1,538,201 | ZAI1 |
| 2015 | Pathways Regulating Lung Transplant Tolerance1P01AI116501-01 · under PAR-13-254 | KREISEL, DANIEL | WASHINGTON UNIVERSITY, MO | $1,460,137 | ZAI1 |
| 2015 | Live Attenuated RSV Vaccine with Optimized Safety and Immunogenicity1P01AI112524-01A1 · under PAR-13-254 | PEEPLES, MARK E.RAMILO, OCTAVIO | RESEARCH INST NATIONWIDE CHILDREN'S HOSP, OH | $749,998 | ZAI1 |
| 2014 | Staphylococcal Biofilm and Disease2P01AI083211-06 · under PAR-13-254 | BAYLES, KENNETH W. | UNIVERSITY OF NEBRASKA MEDICAL CENTER, NE | $2,315,393 | ZAI1 |
| 2014 | Cognitive and immune impairments in sepsis survivors1P01AI102852-01A1 · under PAR-10-271 | DIAMOND, BETTYTRACEY, KEVIN J | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, NY | $2,292,587 | ZAI1 |
| 2014 | Anti-NMDA receptor antibodies in adult brain dsyfunction & fetal brain developmen2P01AI073693-06A1 · under PAR-13-254 | DIAMOND, BETTY | FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH, NY | $2,287,670 | ZAI1 |
| 2014 | T Cell Costimulatory Pathways: Functions and Interactions2P01AI056299-11 · under PAR-13-254 | SHARPE, ARLENE H. | HARVARD MEDICAL SCHOOL, MA | $2,194,909 | ZAI1 |
| 2014 | Mechanisms and Immunological Consequences of Host-Virus Interactions1P01AI112521-01 · under PAR-13-254 | VON ANDRIAN, ULRICH H | HARVARD MEDICAL SCHOOL, MA | $1,972,162 | ZAI1 |
| 2014 | Complement in inflammatory diseases: mechanisms & therapeutic modulation2P01AI068730-06 · under PAR-10-271 | LAMBRIS, JOHN D | UNIVERSITY OF PENNSYLVANIA, PA | $1,921,458 | ZAI1 |
| 2014 | Molecular Basis for gamma/delta T Lineage Specification1P01AI102853-01A1 · under PAR-10-271 | WIEST, DAVID L. | RESEARCH INST OF FOX CHASE CAN CTR, PA | $1,861,695 | ZAI1 |
| 2014 | Tissue regulation of T cell function1P01AI102851-01A1 · under PAR-10-271 | FOWELL, DEBORAH J | UNIVERSITY OF ROCHESTER, NY | $1,714,537 | ZAI1 |
| 2014 | Mechanisms of Transmissibility in Prion Diseases1P01AI106705-01A1 · under PAR-13-254 | SUREWICZ, WITOLD K | CASE WESTERN RESERVE UNIVERSITY, OH | $1,558,580 | ZAI1 |
| 2014 | Quantifying Heterogeneities in Dengue Virus Transmission Dynamics1P01AI098670-01A1 · under PAR-10-271 | SCOTT, THOMAS WALLACE | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $1,393,023 | ZAI1 |
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.