The notices it replaced
- Reissues: RFA-MH-18-701 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01- Clinical Trial Required)
- 2 steps back: RFA-MH-17-608 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01)
- 3 steps back: RFA-MH-16-420 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01)
- 4 steps back: RFA-MH-15-320 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01)
Replaced by PAR-25-177.
Who won it before
69 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $54,681,360 in first-year total cost, median $765,622.
Most frequent study sections
- Mental Health Services Study Section[SERV]15
- Effectiveness of Mental Health Interventions Study Section[EMHI]9
- Special Emphasis Panel[ZMH1 ERB-K (03)]8
- Special Emphasis Panel[ZMH1 ERB-K (07)]6
- Special Emphasis Panel[ZMH1 ERB-B (05)]5
Most frequent institutions
- UNIVERSITY OF MICHIGAN AT ANN ARBOR4
- UNIVERSITY OF WASHINGTON4
- COLUMBIA UNIVERSITY HEALTH SCIENCES3
- WASHINGTON UNIVERSITY3
- DREXEL UNIVERSITY2
| FY | Project | PIs | Institution | First-year cost | Study section |
|---|---|---|---|---|---|
| 2025 | BehavioraL ActIvation for the PreVention of Post-strokE Depression in LoW-incomE OLder Stroke Survivors (LIVE-WEL)1R01MH140091-01 | BEAUCHAMP, JENNIFER ELIZABETH SANNER | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX | $1,340,333 | SERV |
| 2025 | Coaching and Leadership in Autism Support Settings (CLASS)1R01MH135924-01A1 | BEARSS, KAREN ELIZABETHLOCKE, JILL J | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $958,076 | SERV |
| 2025 | Adaptive interventions to improve posttraumatic stress (PTSD) treatment access, engagement, and effectiveness in routine care1R01MH138549-01 | VALENTINE, SARAH E | BOSTON MEDICAL CENTER, MA | $939,784 | EMHI |
| 2025 | Optimizing an automated chatbot to achieve efficient, scalable treatment for eating disorders1R01MH138735-01 | FITZSIMMONS-CRAFT, ELLEN E. | WASHINGTON UNIVERSITY, MO | $841,469 | EMHI |
| 2025 | Evaluating the Effectiveness of Mindfulness-Based Therapy for SMI Implemented in a Community Mental Health Setting1R01MH136540-01A1 | GAUDIANO, BRANDON A | BUTLER HOSPITAL (PROVIDENCE, RI), RI | $768,172 | EMHI |
| 2025 | Integration of a Culturally Responsive Family Peer Delivered Engagement Strategy in Coordinated Specialty Care1R01MH136132-01A1 | OLUWOYE, OLADUNNI | WASHINGTON STATE UNIVERSITY, WA | $756,742 | SERV |
| 2025 | A randomized trial of a video-based family intervention for home visited mothers with perinatal depressive symptoms1R01MH136121-01A1 | CLUXTON-KELLER, FALLON P | DARTMOUTH-HITCHCOCK CLINIC, NH | $663,041 | EMHI |
| 2025 | Single Session Intervention and Interpersonal Therapy for Adolescent Depression in Mozambican Primary Care Clinics: A Hybrid Effectiveness/Implementation Cluster Randomized Trial1R01MH137289-01A1 | GOUVEIA, LIDIALOVERO, KATHRYN LYNN | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $570,966 | SERV |
| 2024 | Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services1R01MH137179-01 | DICKSON, KELSEY S | SAN DIEGO STATE UNIVERSITY, CA | $994,397 | SERV |
| 2024 | Sleep to Reduce Incident Depression Effectively in Peripartum - (STRIDE P)1R01MH129549-01A1 | DRAKE, CHRISTOPHER LKALMBACH, DAVID ADDISON | HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI | $992,063 | EMHI |
| 2024 | Randomized controlled trial of a choice-driven, interactive, storytelling web-based app to investigate mental health treatment initiation among symptomatic Latinas1R01MH137232-01 | HEILEMANN, MARYSUE V | UNIVERSITY OF CALIFORNIA LOS ANGELES, CA | $782,069 | SERV |
| 2024 | Testing tailored text reminders and financial incentives to enhance antidepressant adherence for depressed adults in primary care1R01MH135011-01A1 | MARCUS, STEVEN COLFSON, MARK | UNIVERSITY OF PENNSYLVANIA, PA | $765,622 | SERV |
| 2024 | Hybrid Effectiveness-Implementation Trial of Massed PTSD Treatment in a Community Substance Use Program1R01MH132720-01A1 | HIEN, DENISE AIMEENORMAN, SONYA | RUTGERS, THE STATE UNIV OF N.J., NJ | $754,267 | EMHI |
| 2024 | Community-Embedded, Layperson-Supported Digital Mental Health Intervention for Homebound Older Adults with Depression: A Type 1 Hybrid Effectiveness-Implementation RCT1R01MH137064-01 | XIANG, XIAOLING | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $742,221 | EMHI |
| 2024 | Hybrid Effectiveness-Implementation Trial to Evaluate a Scalable, Peer-Delivered Intervention for Depression among People with Substance Use Disorder in a Certified Community Behavioral Health Clinic1R01MH137237-01 | FELTON, JULIA WMAGIDSON, JESSICA F | HENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI | $734,465 | SERV |
| 2024 | Family Psychoeducation for Adults with Psychotic Disorders in Tanzania (KUPAA trial)1R01MH136145-01 | BAUMGARTNER, JOY NOEL | UNIV OF NORTH CAROLINA CHAPEL HILL, NC | $729,802 | SERV |
| 2024 | Safety Planning and Cognitive Behavioral Therapy for Adolescent Suicide Prevention in Mozambique: A Hybrid Effectiveness/Implementation Cluster Randomized Trial1R01MH134882-01 | WAGENAAR, BRADLEY | UNIVERSITY OF WASHINGTON, WA | $674,905 | SERV |
| 2023 | Effectiveness Trial of Wingman-Connect Implemented Across Career Phases1R01MH131738-01A1 | WYMAN, PETER A | UNIVERSITY OF ROCHESTER, NY | $1,761,380 | EMHI |
| 2023 | Behavioral telehealth in low-resource primary care settings for anxiety and depression in youth: A randomized effectiveness-implementation study1R01MH131698-01A1 | LYNCH, FRANCES LWEERSING, V ROBIN | SAN DIEGO STATE UNIVERSITY, CA | $1,070,654 | SERV |
| 2023 | Examining the Effectiveness of the Early Start Denver Model in Community Programs serving Young Autistic Children1R01MH131703-01A1 | STAHMER, AUBYN C. | UNIVERSITY OF CALIFORNIA AT DAVIS, CA | $938,284 | EMHI |
| 2023 | A Hybrid Effectiveness-Implementation RCT of Virtual Interview Training for Autistic Transition-Age Youth1R01MH132656-01 | SMITH, MATTHEW JAMES | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $837,378 | SERV |
| 2023 | Promoting Emotional Development Among Young Children Facing Adversity: An Effectiveness Implementation Study in St. Louis Schools1R01MH130621-01A1 | KOHL, PATRICIA LYNNLUBY, JOAN L. | WASHINGTON UNIVERSITY, MO | $776,472 | SERV |
| 2023 | A Randomized, Controlled Trial of Crisis Intervention Team (CIT) Mental Health Training for Police Officers1R01MH128500-01A1 | COMPTON, MICHAEL TWATSON, AMY C | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $702,745 | ZMH1 |
| 2023 | Intervention to Reduce Depression Among Elder Abuse Victims: Type 1 Hybrid Trial of Tele-PROTECT1R01MH132757-01 | SIREY, JO ANNE | WEILL MEDICAL COLL OF CORNELL UNIV, NY | $521,776 | SERV |
| 2022 | Improving Outcomes in Depression in Primary Care in a Low Resource Setting1R01MH121632-01A1 · under RFA-MH-18-701 | HOLLON, STEVEN DENNISPATEL, VIKRAM H | HARVARD MEDICAL SCHOOL, MA | $1,327,983 | ZMH1 |
| 2022 | A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care Systems1R01MH130460-01 | BULGER, EILEEN MZATZICK, DOUGLAS F | UNIVERSITY OF WASHINGTON, WA | $790,177 | SERV |
| 2022 | Confirming the Effectiveness and Efficiency of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa1R01MH130388-01 | LOCK, JAMES D | STANFORD UNIVERSITY, CA | $669,677 | ZMH1 |
| 2022 | Optimizing digital health technologies to improve therapeutic skill use and acquisition1R01MH129478-01 | JUARASCIO, ADRIENNE SARAH | DREXEL UNIVERSITY, PA | $664,104 | ZMH1 |
| 2022 | MISC-CBO: A cluster randomized control trial to improve the mental health of OVC in South Africa1R01MH127060-01A1 | SHARP, CARLA | UNIVERSITY OF HOUSTON, TX | $364,477 | ZMH1 |
| 2021 | Delivering Written Exposure Therapy for PTSD in Underserved Primary Care Settings1R01MH123585-01A1 · under RFA-MH-18-701 | MEREDITH, LISA SEIDELSLOAN, DENISE M. | RAND CORPORATION, CA | $1,034,438 | ZMH1 |
| 2021 | ICBT for Maternal Depression: Community Implementation in Head Start1R01MH120237-01A1 · under RFA-MH-18-701 | FEIL, EDWARD GUSTAVSHEEBER, LISA B | OREGON RESEARCH INSTITUTE, OR | $1,007,283 | ZMH1 |
| 2021 | Testing FIRST in Youth Outpatient Psychotherapy1R01MH124965-01 · under RFA-MH-18-701 | BEARMAN, SARAH KATE KATEWEISZ, JOHN RICHARD | HARVARD UNIVERSITY, MA | $955,626 | ZMH1 |
| 2021 | Skills to Enhance Positivity (STEP) for Adolescents at Risk for Suicide1R01MH123556-01A1 · under RFA-MH-18-701 | SPIRITO, ANTHONYYEN, SHIRLEY | BROWN UNIVERSITY, RI | $848,095 | ZMH1 |
| 2021 | Care Team and Practice Level Implementation Strategies to Optimize Pediatric Collaborative Care: A Cluster-Randomized Trial1R01MH124914-01 · under RFA-MH-18-701 | KOLKO, DAVID | UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA | $838,443 | ZMH1 |
| 2021 | Testing Adaptive Interventions to Improve PTSD Treatment Outcomes in Federally Qualified Health Centers1R01MH125857-01A1 · under RFA-MH-18-701 | SRIPADA, REBECCA KAUFMAN | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $807,438 | ZMH1 |
| 2021 | Effectiveness of an Empirically Supported Family Intervention: Mental Health Outcomes, Mechanisms of Effect, and Organizational Factors1R01MH124958-01 · under RFA-MH-18-701 | BERGMAN, KATHLEEN NANETTEBORKOWSKI, JOHN GCUMMINGS, EDWARD MARK | UNIVERSITY OF NOTRE DAME, IN | $756,526 | ZMH1 |
| 2021 | A hybrid effectiveness-implementation trial of a school based executive function treatment for transition age youth with autism1R01MH124772-01 · under RFA-MH-18-701 | PUGLIESE, CARA | CHILDREN'S RESEARCH INSTITUTE, DC | $593,049 | ZMH1 |
| 2020 | A Randomized Controlled Trial of a Telementoring Program, Project ECHO, to increase Clozapine Prescribing1R37MH121564-01 · under RFA-MH-18-701 | KELLY, DEANNA L | UNIVERSITY OF MARYLAND BALTIMORE, MD | $773,580 | ZMH1 |
| 2020 | Optimizing Mindfulness and Acceptance-Based Treatments for Bulimia Nervosa and Binge Eating Disorder using a Factorial Design1R01MH122392-01 · under RFA-MH-18-701 | JUARASCIO, ADRIENNE SARAH | DREXEL UNIVERSITY, PA | $725,362 | ZMH1 |
| 2020 | Effectiveness and Implementation of an Early Childhood School-Based Mental Health Intervention in Low-Resource Communities1R01MH122654-01 · under RFA-MH-18-701 | HUANG, KENG-YENNAKIGUDDE, JANET | NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY | $674,506 | ZMH1 |
| 2020 | Sleep to Reduce Incident Depression Effectively (STRIDE)1R01MH122636-01 · under RFA-MH-18-701 | DRAKE, CHRISTOPHER L | HENRY FORD HEALTH SYSTEM, MI | $514,727 | ZMH1 |
| 2019 | Preventing Suicide in African American Adolescents1R01MH118382-01A1 · under RFA-MH-18-701 | ROBINSON, W LAVOME | DE PAUL UNIVERSITY, IL | $1,235,922 | ZMH1 |
| 2019 | Improving Transition Outcomes for Youth with Autism through Parent Advocacy Training: A Multi-State Randomized Controlled Trial1R01MH116058-01A1 · under RFA-MH-18-701 | TAYLOR, JULIE LOUNDS | VANDERBILT UNIVERSITY MEDICAL CENTER, TN | $857,058 | ZMH1 |
| 2019 | Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health.1R01MH120147-01 · under RFA-MH-18-701 | HARVEY, ALLISON G | UNIVERSITY OF CALIFORNIA BERKELEY, CA | $784,067 | ZMH1 |
| 2019 | Implementing mHealth for Schizophrenia in Community Mental Health Settings1R01MH116057-01A1 · under RFA-MH-18-701 | BEN-ZEEV, DROR | UNIVERSITY OF WASHINGTON, WA | $780,141 | ZMH1 |
| 2019 | Attachment and Biobehavioral Catch-up with Child Protective Services-Involved Parents: Testing Effectiveness in the Community1R01MH119310-01 · under RFA-MH-18-701 | BERNARD, KRISTIN LDOZIER, MARY | STATE UNIVERSITY NEW YORK STONY BROOK, NY | $747,264 | ZMH1 |
| 2019 | Effectiveness of a Targeted Brief Intervention for Recent Suicide Attempt Survivors1R01MH119264-01 · under RFA-MH-18-701 | PISANI, ANTHONY R | UNIVERSITY OF ROCHESTER, NY | $711,407 | ZMH1 |
| 2019 | Effectiveness Research for Common Mental Disorders in Low and Middle Income Countries: A sequential, multiple assignment randomized trial for non-specialist treatment strategies in Kenya1R01MH113722-01A1 · under RFA-MH-18-701 | MEFFERT, SUSAN M. | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA | $661,058 | ZMH1 |
| 2018 | Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations1R01MH115128-01A1 · under RFA-MH-17-608 | EISENBERG, DANIELNEWMAN, MICHELLE GTAYLOR, CRAIG BARRWILFLEY, DENISE ELLA | WASHINGTON UNIVERSITY, MO | $808,455 | ZMH1 |
| 2018 | Multi-component Intervention for Diabetes in Adults with Serious Mental Illness (MIDAS)1R01MH115127-01A1 · under RFA-MH-17-608 | JESTE, DILIP V. | UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA | $770,116 | ZMH1 |
| 2018 | Effectiveness and Implementation of a Peer Mentorship Intervention (PREVAIL) to Reduce Suicide Attempts Among High-Risk Adults1R01MH115111-01 · under RFA-MH-17-608 | PFEIFFER, PAUL NELSON | UNIVERSITY OF MICHIGAN AT ANN ARBOR, MI | $689,585 | ZMH1 |
| 2018 | A Trial of a Police-Mental Health Linkage System for Jail Diversion and Reconnection to Care1R01MH117191-01 · under RFA-MH-17-608 | COMPTON, MICHAEL T | COLUMBIA UNIVERSITY HEALTH SCIENCES, NY | $642,228 | ZMH1 |
| 2018 | Effectiveness and Implementation of PTSD Treatment for Suicidal and Multi-Diagnostic Clients in Community Practice Settings1R56MH117085-01 · under RFA-MH-17-608 | HARNED, MELANIE | SEATTLE INST FOR BIOMEDICAL/CLINICAL RES, WA | $489,886 | ZMH1 |
| 2018 | Sleep to Reduce Incident Depression Effectively (STRIDE)1R56MH115150-01 · under RFA-MH-17-608 | DRAKE, CHRISTOPHER L | HENRY FORD HEALTH SYSTEM, MI | $416,893 | ZMH1 |
| 2017 | Improving Quality of Care in Child Mental Health Service Settings1R01MH110620-01A1 · under RFA-MH-16-420 | RUGGIERO, KENNETH J | MEDICAL UNIVERSITY OF SOUTH CAROLINA, SC | $840,610 | ZMH1 |
| 2017 | An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression1R01MH113748-01 · under RFA-MH-16-420 | GUNLICKS-STOESSEL, MEREDITH LYN | UNIVERSITY OF MINNESOTA, MN | $589,410 | ZMH1 |
| 2017 | Effectiveness of interpretation training to reduce anxiety: Evaluating technology-based delivery models and methods to reduce attrition1R01MH113752-01 · under RFA-MH-16-420 | TEACHMAN, BETHANY A | UNIVERSITY OF VIRGINIA, VA | $589,183 | ZMH1 |
| 2017 | An anxiety-focused early prenatal intervention for the prevention of common mental disorders in Pakistan1R01MH111859-01 · under RFA-MH-16-420 | SURKAN, PAMELA J | JOHNS HOPKINS UNIVERSITY, MD | $517,182 | ZMH1 |
| 2017 | Effectiveness of a Mobile Texting Intervention for People with Serious Mental Illness1R56MH109554-01A1 · under RFA-MH-16-420 | BEN-ZEEV, DROR | UNIVERSITY OF WASHINGTON, WA | $293,503 | ZMH1 |
| 2016 | Effectiveness Trial of Treatment to Reduce Serious Antisocial Behavior in Emerging Adults with Mental Illness1R01MH108793-01 · under RFA-MH-15-320 | DAVIS, MARYANNSHEIDOW, ASHLI J | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $778,570 | ZMH1 |
| 2016 | LiveWell: A Mobile Intervention for Bipolar Disorder1R01MH110626-01 · under RFA-MH-16-420 | GOULDING, EVAN H. | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $769,879 | ZMH1 |
| 2016 | Virtual Reality Job Interview Training to Enhance Supported Employment for Adults with SMI1R01MH110524-01 · under RFA-MH-16-420 | SMITH, MATTHEW JAMES | NORTHWESTERN UNIVERSITY AT CHICAGO, IL | $530,819 | ZMH1 |
| 2015 | Suicide risk reduction in the year following jail release: the SPIRIT Trial (Suicide Prevention Intervention for at-Risk Individuals in Transition)1U01MH106660-01A1 · under RFA-MH-15-320 | JOHNSON, JENNIFER EWEINSTOCK, LAUREN M | MICHIGAN STATE UNIVERSITY, MI | $1,820,223 | ZMH1 |
| 2015 | ED-SAFE 2: Translating Safety Planning into Practice1R01MH106726-01 · under RFA-MH-15-320 | BOUDREAUX, EDWIN D | UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA | $1,154,139 | ZMH1 |
| 2015 | Family Groups for Urban Youth with Disruptive Behavior1R01MH106771-01 · under RFA-MH-15-320 | MCKAY, MARY MCKERNAN | NEW YORK UNIVERSITY, NY | $787,927 | ZMH1 |
| 2015 | Automated Telehealth to Improve Psychiatric Self-Management and Community Tenure1R01MH107625-01 · under RFA-MH-15-320 | PRATT, SARAH ILANA | DARTMOUTH COLLEGE, NH | $757,389 | ZMH1 |
| 2015 | Stepped Care for Children after Trauma: Optimizing Treatment1R01MH107522-01 · under RFA-MH-15-320 | SALLOUM, ALISON ANN | UNIVERSITY OF SOUTH FLORIDA, FL | $623,732 | ZMH1 |
| 2015 | Bounce Back Now: A Low-Cost Intervention to Facilitate Post-Disaster Recovery1R01MH107641-01 · under RFA-MH-15-320 | GALEA, SANDRORUGGIERO, KENNETH J | MEDICAL UNIVERSITY OF SOUTH CAROLINA, SC | $606,157 | ZMH1 |
| 2015 | Effectiveness of MI Enhanced Behavior Therapy for Adolescents with ADHD1R01MH106587-01 · under RFA-MH-15-320 | SIBLEY, MARGARET HARPER | FLORIDA INTERNATIONAL UNIVERSITY, FL | $465,983 | ZMH1 |
Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.