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NIH funding notice PAR-25-177

Full-Scale Hybrid Effectiveness-Implementation Trials for Mental Health Interventions (R01 - Clinical Trial Required)

Open. Closes October 15, 2027.

Posted
November 26, 2024
Close date
October 15, 2027
Activity codes
R01
Institutes taking part
NIMH

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-21-130 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01 Clinical Trial Required)
  2. 2 steps back: RFA-MH-18-701 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01- Clinical Trial Required)
  3. 3 steps back: RFA-MH-17-608 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01)
  4. 4 steps back: RFA-MH-16-420 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01)
  5. 5 steps back: RFA-MH-15-320 Clinical Trials to Test the Effectiveness of Treatment, Preventive, and Services Interventions (R01)

Who won it before

69 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $54,681,360 in first-year total cost, median $765,622.

Most frequent study sections

  1. Mental Health Services Study Section[SERV]15
  2. Effectiveness of Mental Health Interventions Study Section[EMHI]9
  3. Special Emphasis Panel[ZMH1 ERB-K (03)]8
  4. Special Emphasis Panel[ZMH1 ERB-K (07)]6
  5. Special Emphasis Panel[ZMH1 ERB-B (05)]5

Most frequent institutions

  1. UNIVERSITY OF MICHIGAN AT ANN ARBOR4
  2. UNIVERSITY OF WASHINGTON4
  3. COLUMBIA UNIVERSITY HEALTH SCIENCES3
  4. WASHINGTON UNIVERSITY3
  5. DREXEL UNIVERSITY2
Competing awards under PAR-25-177 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025BehavioraL ActIvation for the PreVention of Post-strokE Depression in LoW-incomE OLder Stroke Survivors (LIVE-WEL)1R01MH140091-01 · under PAR-21-130BEAUCHAMP, JENNIFER ELIZABETH SANNERUNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON, TX$1,340,333SERV
2025Coaching and Leadership in Autism Support Settings (CLASS)1R01MH135924-01A1 · under PAR-21-130BEARSS, KAREN ELIZABETHLOCKE, JILL JUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$958,076SERV
2025Adaptive interventions to improve posttraumatic stress (PTSD) treatment access, engagement, and effectiveness in routine care1R01MH138549-01 · under PAR-21-130VALENTINE, SARAH EBOSTON MEDICAL CENTER, MA$939,784EMHI
2025Optimizing an automated chatbot to achieve efficient, scalable treatment for eating disorders1R01MH138735-01 · under PAR-21-130FITZSIMMONS-CRAFT, ELLEN E.WASHINGTON UNIVERSITY, MO$841,469EMHI
2025Evaluating the Effectiveness of Mindfulness-Based Therapy for SMI Implemented in a Community Mental Health Setting1R01MH136540-01A1 · under PAR-21-130GAUDIANO, BRANDON ABUTLER HOSPITAL (PROVIDENCE, RI), RI$768,172EMHI
2025Integration of a Culturally Responsive Family Peer Delivered Engagement Strategy in Coordinated Specialty Care1R01MH136132-01A1 · under PAR-21-130OLUWOYE, OLADUNNIWASHINGTON STATE UNIVERSITY, WA$756,742SERV
2025A randomized trial of a video-based family intervention for home visited mothers with perinatal depressive symptoms1R01MH136121-01A1 · under PAR-21-130CLUXTON-KELLER, FALLON PDARTMOUTH-HITCHCOCK CLINIC, NH$663,041EMHI
2025Single Session Intervention and Interpersonal Therapy for Adolescent Depression in Mozambican Primary Care Clinics: A Hybrid Effectiveness/Implementation Cluster Randomized Trial1R01MH137289-01A1 · under PAR-21-130GOUVEIA, LIDIALOVERO, KATHRYN LYNNCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$570,966SERV
2024Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services1R01MH137179-01 · under PAR-21-130DICKSON, KELSEY SSAN DIEGO STATE UNIVERSITY, CA$994,397SERV
2024Sleep to Reduce Incident Depression Effectively in Peripartum - (STRIDE P)1R01MH129549-01A1 · under PAR-21-130DRAKE, CHRISTOPHER LKALMBACH, DAVID ADDISONHENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI$992,063EMHI
2024Randomized controlled trial of a choice-driven, interactive, storytelling web-based app to investigate mental health treatment initiation among symptomatic Latinas1R01MH137232-01 · under PAR-21-130HEILEMANN, MARYSUE VUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$782,069SERV
2024Testing tailored text reminders and financial incentives to enhance antidepressant adherence for depressed adults in primary care1R01MH135011-01A1 · under PAR-21-130MARCUS, STEVEN COLFSON, MARKUNIVERSITY OF PENNSYLVANIA, PA$765,622SERV
2024Hybrid Effectiveness-Implementation Trial of Massed PTSD Treatment in a Community Substance Use Program1R01MH132720-01A1 · under PAR-21-130HIEN, DENISE AIMEENORMAN, SONYARUTGERS, THE STATE UNIV OF N.J., NJ$754,267EMHI
2024Community-Embedded, Layperson-Supported Digital Mental Health Intervention for Homebound Older Adults with Depression: A Type 1 Hybrid Effectiveness-Implementation RCT1R01MH137064-01 · under PAR-21-130XIANG, XIAOLINGUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$742,221EMHI
2024Hybrid Effectiveness-Implementation Trial to Evaluate a Scalable, Peer-Delivered Intervention for Depression among People with Substance Use Disorder in a Certified Community Behavioral Health Clinic1R01MH137237-01 · under PAR-21-130FELTON, JULIA WMAGIDSON, JESSICA FHENRY FORD HEALTH + MICHIGAN STATE UNIVERSITY HEALTH SCIENCES, MI$734,465SERV
2024Family Psychoeducation for Adults with Psychotic Disorders in Tanzania (KUPAA trial)1R01MH136145-01 · under PAR-21-130BAUMGARTNER, JOY NOELUNIV OF NORTH CAROLINA CHAPEL HILL, NC$729,802SERV
2024Safety Planning and Cognitive Behavioral Therapy for Adolescent Suicide Prevention in Mozambique: A Hybrid Effectiveness/Implementation Cluster Randomized Trial1R01MH134882-01 · under PAR-21-130WAGENAAR, BRADLEYUNIVERSITY OF WASHINGTON, WA$674,905SERV
2023Effectiveness Trial of Wingman-Connect Implemented Across Career Phases1R01MH131738-01A1 · under PAR-21-130WYMAN, PETER AUNIVERSITY OF ROCHESTER, NY$1,761,380EMHI
2023Behavioral telehealth in low-resource primary care settings for anxiety and depression in youth: A randomized effectiveness-implementation study1R01MH131698-01A1 · under PAR-21-130LYNCH, FRANCES LWEERSING, V ROBINSAN DIEGO STATE UNIVERSITY, CA$1,070,654SERV
2023Examining the Effectiveness of the Early Start Denver Model in Community Programs serving Young Autistic Children1R01MH131703-01A1 · under PAR-21-130STAHMER, AUBYN C.UNIVERSITY OF CALIFORNIA AT DAVIS, CA$938,284EMHI
2023A Hybrid Effectiveness-Implementation RCT of Virtual Interview Training for Autistic Transition-Age Youth1R01MH132656-01 · under PAR-21-130SMITH, MATTHEW JAMESUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$837,378SERV
2023Promoting Emotional Development Among Young Children Facing Adversity: An Effectiveness Implementation Study in St. Louis Schools1R01MH130621-01A1 · under PAR-21-130KOHL, PATRICIA LYNNLUBY, JOAN L.WASHINGTON UNIVERSITY, MO$776,472SERV
2023A Randomized, Controlled Trial of Crisis Intervention Team (CIT) Mental Health Training for Police Officers1R01MH128500-01A1 · under PAR-21-130COMPTON, MICHAEL TWATSON, AMY CCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$702,745ZMH1
2023Intervention to Reduce Depression Among Elder Abuse Victims: Type 1 Hybrid Trial of Tele-PROTECT1R01MH132757-01 · under PAR-21-130SIREY, JO ANNEWEILL MEDICAL COLL OF CORNELL UNIV, NY$521,776SERV
2022Improving Outcomes in Depression in Primary Care in a Low Resource Setting1R01MH121632-01A1 · under RFA-MH-18-701HOLLON, STEVEN DENNISPATEL, VIKRAM HHARVARD MEDICAL SCHOOL, MA$1,327,983ZMH1
2022A Deployment Focused Pragmatic Trial of Optimal Stepped Care Intervention Targeting PTSD and Comorbidity for Acutely Hospitalized Injury Survivors Treated in US Trauma Care Systems1R01MH130460-01 · under PAR-21-130BULGER, EILEEN MZATZICK, DOUGLAS FUNIVERSITY OF WASHINGTON, WA$790,177SERV
2022Confirming the Effectiveness and Efficiency of Online Guided Self-Help Family-Based Treatment for Adolescent Anorexia Nervosa1R01MH130388-01 · under PAR-21-130LOCK, JAMES DSTANFORD UNIVERSITY, CA$669,677ZMH1
2022Optimizing digital health technologies to improve therapeutic skill use and acquisition1R01MH129478-01 · under PAR-21-130JUARASCIO, ADRIENNE SARAHDREXEL UNIVERSITY, PA$664,104ZMH1
2022MISC-CBO: A cluster randomized control trial to improve the mental health of OVC in South Africa1R01MH127060-01A1 · under PAR-21-130SHARP, CARLAUNIVERSITY OF HOUSTON, TX$364,477ZMH1
2021Delivering Written Exposure Therapy for PTSD in Underserved Primary Care Settings1R01MH123585-01A1 · under RFA-MH-18-701MEREDITH, LISA SEIDELSLOAN, DENISE M.RAND CORPORATION, CA$1,034,438ZMH1
2021ICBT for Maternal Depression: Community Implementation in Head Start1R01MH120237-01A1 · under RFA-MH-18-701FEIL, EDWARD GUSTAVSHEEBER, LISA BOREGON RESEARCH INSTITUTE, OR$1,007,283ZMH1
2021Testing FIRST in Youth Outpatient Psychotherapy1R01MH124965-01 · under RFA-MH-18-701BEARMAN, SARAH KATE KATEWEISZ, JOHN RICHARDHARVARD UNIVERSITY, MA$955,626ZMH1
2021Skills to Enhance Positivity (STEP) for Adolescents at Risk for Suicide1R01MH123556-01A1 · under RFA-MH-18-701SPIRITO, ANTHONYYEN, SHIRLEYBROWN UNIVERSITY, RI$848,095ZMH1
2021Care Team and Practice Level Implementation Strategies to Optimize Pediatric Collaborative Care: A Cluster-Randomized Trial1R01MH124914-01 · under RFA-MH-18-701KOLKO, DAVIDUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$838,443ZMH1
2021Testing Adaptive Interventions to Improve PTSD Treatment Outcomes in Federally Qualified Health Centers1R01MH125857-01A1 · under RFA-MH-18-701SRIPADA, REBECCA KAUFMANUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$807,438ZMH1
2021Effectiveness of an Empirically Supported Family Intervention: Mental Health Outcomes, Mechanisms of Effect, and Organizational Factors1R01MH124958-01 · under RFA-MH-18-701BERGMAN, KATHLEEN NANETTEBORKOWSKI, JOHN GCUMMINGS, EDWARD MARKUNIVERSITY OF NOTRE DAME, IN$756,526ZMH1
2021A hybrid effectiveness-implementation trial of a school based executive function treatment for transition age youth with autism1R01MH124772-01 · under RFA-MH-18-701PUGLIESE, CARACHILDREN'S RESEARCH INSTITUTE, DC$593,049ZMH1
2020A Randomized Controlled Trial of a Telementoring Program, Project ECHO, to increase Clozapine Prescribing1R37MH121564-01 · under RFA-MH-18-701KELLY, DEANNA LUNIVERSITY OF MARYLAND BALTIMORE, MD$773,580ZMH1
2020Optimizing Mindfulness and Acceptance-Based Treatments for Bulimia Nervosa and Binge Eating Disorder using a Factorial Design1R01MH122392-01 · under RFA-MH-18-701JUARASCIO, ADRIENNE SARAHDREXEL UNIVERSITY, PA$725,362ZMH1
2020Effectiveness and Implementation of an Early Childhood School-Based Mental Health Intervention in Low-Resource Communities1R01MH122654-01 · under RFA-MH-18-701HUANG, KENG-YENNAKIGUDDE, JANETNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$674,506ZMH1
2020Sleep to Reduce Incident Depression Effectively (STRIDE)1R01MH122636-01 · under RFA-MH-18-701DRAKE, CHRISTOPHER LHENRY FORD HEALTH SYSTEM, MI$514,727ZMH1
2019Preventing Suicide in African American Adolescents1R01MH118382-01A1 · under RFA-MH-18-701ROBINSON, W LAVOMEDE PAUL UNIVERSITY, IL$1,235,922ZMH1
2019Improving Transition Outcomes for Youth with Autism through Parent Advocacy Training: A Multi-State Randomized Controlled Trial1R01MH116058-01A1 · under RFA-MH-18-701TAYLOR, JULIE LOUNDSVANDERBILT UNIVERSITY MEDICAL CENTER, TN$857,058ZMH1
2019Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment to Improve Severe Mental Illness Outcomes in Community Mental Health.1R01MH120147-01 · under RFA-MH-18-701HARVEY, ALLISON GUNIVERSITY OF CALIFORNIA BERKELEY, CA$784,067ZMH1
2019Implementing mHealth for Schizophrenia in Community Mental Health Settings1R01MH116057-01A1 · under RFA-MH-18-701BEN-ZEEV, DRORUNIVERSITY OF WASHINGTON, WA$780,141ZMH1
2019Attachment and Biobehavioral Catch-up with Child Protective Services-Involved Parents: Testing Effectiveness in the Community1R01MH119310-01 · under RFA-MH-18-701BERNARD, KRISTIN LDOZIER, MARYSTATE UNIVERSITY NEW YORK STONY BROOK, NY$747,264ZMH1
2019Effectiveness of a Targeted Brief Intervention for Recent Suicide Attempt Survivors1R01MH119264-01 · under RFA-MH-18-701PISANI, ANTHONY RUNIVERSITY OF ROCHESTER, NY$711,407ZMH1
2019Effectiveness Research for Common Mental Disorders in Low and Middle Income Countries: A sequential, multiple assignment randomized trial for non-specialist treatment strategies in Kenya1R01MH113722-01A1 · under RFA-MH-18-701MEFFERT, SUSAN M.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$661,058ZMH1
2018Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations1R01MH115128-01A1 · under RFA-MH-17-608EISENBERG, DANIELNEWMAN, MICHELLE GTAYLOR, CRAIG BARRWILFLEY, DENISE ELLAWASHINGTON UNIVERSITY, MO$808,455ZMH1
2018Multi-component Intervention for Diabetes in Adults with Serious Mental Illness (MIDAS)1R01MH115127-01A1 · under RFA-MH-17-608JESTE, DILIP V.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$770,116ZMH1
2018Effectiveness and Implementation of a Peer Mentorship Intervention (PREVAIL) to Reduce Suicide Attempts Among High-Risk Adults1R01MH115111-01 · under RFA-MH-17-608PFEIFFER, PAUL NELSONUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$689,585ZMH1
2018A Trial of a Police-Mental Health Linkage System for Jail Diversion and Reconnection to Care1R01MH117191-01 · under RFA-MH-17-608COMPTON, MICHAEL TCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$642,228ZMH1
2018Effectiveness and Implementation of PTSD Treatment for Suicidal and Multi-Diagnostic Clients in Community Practice Settings1R56MH117085-01 · under RFA-MH-17-608HARNED, MELANIESEATTLE INST FOR BIOMEDICAL/CLINICAL RES, WA$489,886ZMH1
2018Sleep to Reduce Incident Depression Effectively (STRIDE)1R56MH115150-01 · under RFA-MH-17-608DRAKE, CHRISTOPHER LHENRY FORD HEALTH SYSTEM, MI$416,893ZMH1
2017Improving Quality of Care in Child Mental Health Service Settings1R01MH110620-01A1 · under RFA-MH-16-420RUGGIERO, KENNETH JMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$840,610ZMH1
2017An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression1R01MH113748-01 · under RFA-MH-16-420GUNLICKS-STOESSEL, MEREDITH LYNUNIVERSITY OF MINNESOTA, MN$589,410ZMH1
2017Effectiveness of interpretation training to reduce anxiety: Evaluating technology-based delivery models and methods to reduce attrition1R01MH113752-01 · under RFA-MH-16-420TEACHMAN, BETHANY AUNIVERSITY OF VIRGINIA, VA$589,183ZMH1
2017An anxiety-focused early prenatal intervention for the prevention of common mental disorders in Pakistan1R01MH111859-01 · under RFA-MH-16-420SURKAN, PAMELA JJOHNS HOPKINS UNIVERSITY, MD$517,182ZMH1
2017Effectiveness of a Mobile Texting Intervention for People with Serious Mental Illness1R56MH109554-01A1 · under RFA-MH-16-420BEN-ZEEV, DRORUNIVERSITY OF WASHINGTON, WA$293,503ZMH1
2016Effectiveness Trial of Treatment to Reduce Serious Antisocial Behavior in Emerging Adults with Mental Illness1R01MH108793-01 · under RFA-MH-15-320DAVIS, MARYANNSHEIDOW, ASHLI JUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$778,570ZMH1
2016LiveWell: A Mobile Intervention for Bipolar Disorder1R01MH110626-01 · under RFA-MH-16-420GOULDING, EVAN H.NORTHWESTERN UNIVERSITY AT CHICAGO, IL$769,879ZMH1
2016Virtual Reality Job Interview Training to Enhance Supported Employment for Adults with SMI1R01MH110524-01 · under RFA-MH-16-420SMITH, MATTHEW JAMESNORTHWESTERN UNIVERSITY AT CHICAGO, IL$530,819ZMH1
2015Suicide risk reduction in the year following jail release: the SPIRIT Trial (Suicide Prevention Intervention for at-Risk Individuals in Transition)1U01MH106660-01A1 · under RFA-MH-15-320JOHNSON, JENNIFER EWEINSTOCK, LAUREN MMICHIGAN STATE UNIVERSITY, MI$1,820,223ZMH1
2015ED-SAFE 2: Translating Safety Planning into Practice1R01MH106726-01 · under RFA-MH-15-320BOUDREAUX, EDWIN DUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$1,154,139ZMH1
2015Family Groups for Urban Youth with Disruptive Behavior1R01MH106771-01 · under RFA-MH-15-320MCKAY, MARY MCKERNANNEW YORK UNIVERSITY, NY$787,927ZMH1
2015Automated Telehealth to Improve Psychiatric Self-Management and Community Tenure1R01MH107625-01 · under RFA-MH-15-320PRATT, SARAH ILANADARTMOUTH COLLEGE, NH$757,389ZMH1
2015Stepped Care for Children after Trauma: Optimizing Treatment1R01MH107522-01 · under RFA-MH-15-320SALLOUM, ALISON ANNUNIVERSITY OF SOUTH FLORIDA, FL$623,732ZMH1
2015Bounce Back Now: A Low-Cost Intervention to Facilitate Post-Disaster Recovery1R01MH107641-01 · under RFA-MH-15-320GALEA, SANDRORUGGIERO, KENNETH JMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$606,157ZMH1
2015Effectiveness of MI Enhanced Behavior Therapy for Adolescents with ADHD1R01MH106587-01 · under RFA-MH-15-320SIBLEY, MARGARET HARPERFLORIDA INTERNATIONAL UNIVERSITY, FL$465,983ZMH1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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