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NIH funding notice PAR-25-052

NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)

Open. Closes November 19, 2026.

Posted
November 20, 2024
Close date
November 19, 2026
Activity codes
UG3, UH3
Institutes taking part
NINDS

Read the notice on Grants.gov · NIH Guide page

The notices it replaced

  1. Reissues: PAR-24-101 NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)
  2. 2 steps back: PAR-20-285 NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional)
  3. 3 steps back: PAR-18-561 NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U01 - Clinical Trial Optional)
  4. 4 steps back: PAR-17-274 NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U01)
  5. 5 steps back: PAR-14-220 NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (U01)

Who won it before

20 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $81,859,310 in first-year total cost, median $3,986,475.

Most frequent study sections

  1. Special Emphasis Panel[ZNS1 SRB-G (33)]3
  2. Special Emphasis Panel[ZNS1 SRB-G (14)]2
  3. Special Emphasis Panel[ZNS1 SRB-H (01)]2
  4. Special Emphasis Panel[ZNS1 SRB-W (01)]2
  5. Neurological Sciences and Disorders K Study Section[NSD-K]1

Most frequent institutions

  1. UNIVERSITY OF CINCINNATI4
  2. STANFORD UNIVERSITY3
  3. BETH ISRAEL DEACONESS MEDICAL CENTER2
  4. YALE UNIVERSITY2
  5. COLUMBIA UNIVERSITY HEALTH SCIENCES1
Competing awards under PAR-25-052 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2025Cilostazol for Prevention of Recurrent Stroke (CLARITY)1UG3NS133209-01A1 · under PAR-24-101DE HAVENON, ADAM H.LANSBERG, MAARTEN GSHETH, KEVIN NAVINSTANFORD UNIVERSITY, CA$5,747,701ZNS1
2025Minimally Invasive Neuroendoscopic Ultra-Early Targeted ICH Evacuation (MINUTE) Trial1UG3NS138638-01A1 · under PAR-24-101MOCCO, J DUFFYSELIM, MAGDY HYEATTS, SHARON DZIUBAICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, NY$2,336,853ZNS1
2024Telerehabilitation In The Home After Stroke: A Randomized, Controlled, Assessor-Blind Clinical Trial (The TR-2 Trial)1UG3NS133283-01A1 · under PAR-20-285CRAMER, STEVEN C.EDWARDS, DYLAN JAMESUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$4,408,773ZNS1
2023Strategy for Improving Stroke Treatment Response (SISTER) Trial1UG3NS125023-01A1 · under PAR-20-285ELM, JORDAN J.KHATRI, POOJAMISTRY, EVAREED, GUY LUNIVERSITY OF CINCINNATI, OH$5,110,320ZNS1
2023CAPTIVA-MRI1UG3NS130228-01 · under PAR-20-285AMIN-HANJANI, SEPIDEHCHATTERJEE, ARINDAM R.DE HAVENON, ADAM H.LIEBESKIND, DAVID SIGMUNDYALE UNIVERSITY, CT$1,906,569ZNS1
2023FOcal Cerebral Arteriopathy Steroids (FOCAS) Trial1UG3NS119702-01A1 · under PAR-20-285ELKIND, MITCHELL SFULLERTON, HEATHER JUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$1,773,264ZNS1
2022ZZ-3K3A-301: A multicenter, randomized, placebo-controlled, double-blinded, Phase 3 study to evaluate the efficacy and safety of 3K3A-APC (RHAPSODY-2)1UG3NS119199-01A1 · under PAR-20-285LYDEN, PATRICK DUNIVERSITY OF SOUTHERN CALIFORNIA, CA$3,980,070ZNS1
2021Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis1U01NS117450-01A1 · under PAR-18-561CHIMOWITZ, MARC IVORHOH, BRIAN LIMUNIVERSITY OF FLORIDA, FL$8,624,024ZNS1
2021Validation of Early Prognostic Data for Recovery Outcomes after Stroke for Future, Higher Yield Trials (VERIFY)1U01NS120910-01 · under PAR-18-561CRAMER, STEVEN C.KHATRI, POOJASTINEAR, CATHYVAGAL, ACHALA SAMEERUNIVERSITY OF CINCINNATI, OH$3,992,880ZNS1
2021StAtins Use in intRacereberal hemorrhage patieNts MRI (SATURN MRI) Ancillary Study1UF1NS120871-01 · under PAR-18-561SELIM, MAGDY HSHOAMANESH, ASHKANBETH ISRAEL DEACONESS MEDICAL CENTER, MA$2,705,364ZNS1
2020FVIIa for Acute hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial1U01NS110772-01 · under PAR-18-561BRODERICK, JOSEPH PAULELM, JORDAN J.GROTTA, JAMES CNAIDECH, ANDREW MUNIVERSITY OF CINCINNATI, OH$6,472,265ZNS1
2019Anticoagulation in ICH Survivors for Prevention and Recovery (ASPIRE)1U01NS106513-01A1 · under PAR-18-561KAMEL, HOOMANSHETH, KEVIN NAVINYALE UNIVERSITY, CT$4,032,209ZNS1
2019StATins Use in intRacerebral hemorrhage patieNts (SATURN)1U01NS102289-01A1 · under PAR-17-274SELIM, MAGDY HBETH ISRAEL DEACONESS MEDICAL CENTER, MA$3,014,650ZNS1
2019Perinatal Arterial Stroke: A Multi-site RCT of Intensive Infant Rehabilitation (I-ACQUIRE)1U01NS106655-01A1 · under PAR-18-561LO, WARREN DAVIDRAMEY, SHARON LANDESMANVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$2,926,648ZNS1
2019ARCADIA CSI (Cognition and Silent Infarcts)1U01NS110728-01 · under PAR-18-561LANSBERG, MAARTEN GLAZAR, RONALD MSTANFORD UNIVERSITY, CA$1,922,432ZNS1
2018Sleep for Stroke Management And Recovery Trial (Sleep SMART)1U01NS099043-01A1 · under PAR-14-220BROWN, DEVIN LCHERVIN, RONALD DUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$7,487,394ZNS1
2018Multi-arm Optimization of Stroke Thrombolysis (MOST) Stroke Trial1U01NS100699-01A1 · under PAR-14-220ADEOYE, OPEOLU MBARRETO, ANDREW DBRODERICK, JOSEPH PAULGROTTA, JAMES CUNIVERSITY OF CINCINNATI, OH$5,966,429ZNS1
2018TRANScranial direct current stimulation for POst-stroke motor Recover - a phase II sTudy (TRANSPORT 2)1U01NS102353-01A1 · under PAR-17-274FENG, WUWEISCHLAUG, GOTTFRIEDMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$2,445,380ZNS1
2017AtRial Cardiopathy and Antithrombotic Drugs In prevention After cryptogenicstroke (ARCADIA)1U01NS095869-01A1 · under PAR-14-220BRODERICK, JOSEPH PAULELKIND, MITCHELL SKAMEL, HOOMANLONGSTRETH, WTMEINZER, CAITLYN NTIRSCHWELL, DAVID LCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$4,072,827NSD
2015DEFUSE 3: EnDovascular ThErapy Following Imaging EvalUation for ISchemic StrokE 31U01NS092076-01A1 · under PAR-14-220ALBERS, GREGORY WSTANFORD UNIVERSITY, CA$2,933,258ZNS1

Data: Grants.gov's daily extract and NIH's notice pages and award files, in ScienceGraph release conductgrants-2026-11-09-0.1.0. An award is listed only where NIH's own record names the notice, and a PI only by NIH's profile ID. Grants.gov and NIH do not endorse ScienceDex.

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PAR-25-052: NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) | ScienceDex | ConductScience