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NIH funding notice PAS-15-055

High Priority Immunology Grants (R01)

Closed on January 7, 2018.

Posted
December 4, 2014
Close date
January 7, 2018
Activity codes
Not stated on the notice page
Institutes taking part
Not stated on the notice page

Read the notice on Grants.gov ยท NIH Guide page

The notices it replaced

Its page was not saved, so the notices it replaced are not known.

Who won it before

295 competing awards (new and renewals) from FY2014 to FY2025 under this notice and the notices it replaced: $140,418,184 in first-year total cost, median $442,500.

Most frequent study sections

  1. Cellular and Molecular Immunology - B Study Section[CMIB]41
  2. Cellular and Molecular Immunology - A Study Section[CMIA]34
  3. Immunity and Host Defense Study Section[IHD]26
  4. Hypersensitivity, Autoimmune, and Immune-mediated Diseases Study Section[HAI]25
  5. Transplantation, Tolerance, and Tumor Immunology Study Section[TTT]24

Most frequent institutions

  1. WASHINGTON UNIVERSITY10
  2. LA JOLLA INSTITUTE FOR IMMUNOLOGY9
  3. MAYO CLINIC ROCHESTER8
  4. UNIV OF MASSACHUSETTS MED SCH WORCESTER8
  5. UNIVERSITY OF PITTSBURGH AT PITTSBURGH8
Competing awards under PAS-15-055 and the notices it replaced
FYProjectPIsInstitutionFirst-year costStudy section
2019Transcriptional Control of Natural Killer Cell Development2R01AI106352-16KEE, BARBARA L.UNIVERSITY OF CHICAGO, IL$486,000ZRG1
2018Role and Regulation of TSLP in Childhood Allergic Disease1R01AI127392-01A1KHURANA HERSHEY, GURJIT K.CINCINNATI CHILDRENS HOSP MED CTR, OH$794,998LCMI
2018Transcriptomic Signatures of Influenza Vaccine Responses1R01AI132348-01A1KENNEDY, RICHARD BPOLAND, GREGORY A.MAYO CLINIC ROCHESTER, MN$778,388VMD
2018Systems Biology of Mumps Vaccine Response1R01AI138965-01KENNEDY, RICHARD BMAYO CLINIC ROCHESTER, MN$767,943IRAP
2018Integrated Functional Histopathology of the Diabetic Human Pancreas1R01AI134971-01HOMANN, DIRKVON HERRATH, MATTHIAS G.LA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$719,000HAI
2018Intestinal allograft tolerance in large animals1R01AI138547-01SYKES, MEGANYAMADA, KAZUHIKOCOLUMBIA UNIVERSITY HEALTH SCIENCES, NY$688,585TTT
2018Harnessing Tissue Resident Memory T Cells for Immunotherapy of Herpes Virus Infections1R01AI134878-01A1COREY, LAWRENCEFRED HUTCHINSON CANCER RESEARCH CENTER, WA$686,493VMD
2018Targeting the IL-2/regulatory T cell axis for autoimmune disease prevention in realistic animal models1R01AI136475-01CAMPBELL, DANIEL JGAVIN, MARC AZIEGLER, STEVEN FBENAROYA RESEARCH INST AT VIRGINIA MASON, WA$679,264TTT
2018CIS-REGULATORY CIRCUITS FOR ILC FUNCTION AND PLASTICITY1R01AI134035-01A1COLONNA, MARCOOLTZ, EUGENE MWASHINGTON UNIVERSITY, MO$654,900CMIA
2018Regulation of Gene Expression in the anaphylactic Pathway1R01AI135194-01A1HUANG, HUANATIONAL JEWISH HEALTH, CO$644,534ZRG1
2018Initiators, biomarkers and mechanisms of epithelial dysfunction and immune pathogenesis in chronic rhinosinusitis and aspirin exacerbated respiratory disease (AERD)1R01AI137174-01SCHLEIMER, ROBERT PNORTHWESTERN UNIVERSITY AT CHICAGO, IL$643,237ZRG1
2018Repertoire studies of human antibodies to RSV and MPV F1R01AI137523-01JARDETZKY, THEODORE SSTANFORD UNIVERSITY, CA$643,125VIRB
2018The role of HLA and its coreceptors in endothelial cell activation and leukocyte recruitment in antibody-mediated transplant rejection1R01AI135201-01A1REED, ELAINE FUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$634,147TTT
2018NK T Cell Interactions with NK Cells During Viral Infection2R01AI046709-15A1BROSSAY, LAURENTBROWN UNIVERSITY, RI$618,272IHD
2018Low dose IL-2 and human regulatory T cells1R01AI131648-01A1MALEK, THOMAS RUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$616,712ZRG1
2018Host nutrients permit immune evasion of NKT cell anti-bacterial responses1R01AI137230-01KRONENBERG, MITCHELLZAJONC, DIRK MLA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$615,389III
2018Translational Regulation of T Regulatory Cells1R01AI137067-01SCHNEIDER, ROBERT JAYNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$600,056CMIA
2018Differential roles for type I interferon and inflammatory pathways in autoimmune diabetes1R01AI139095-01WANG, JENNIFER PUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$592,406HAI
2018Infections, Microbiome and HLA-DR in the Induction of Lupus Related Auto-antibodies1R01AI139673-01FU, SHU MANUNIVERSITY OF VIRGINIA, VA$587,986HAI
2018Co-Presentation and Delivery of TLR Agonist Combinations with Subunit Antigens to Pathogen-Match the Immune Response1R01AI139664-01PUTNAM, DAVID ACORNELL UNIVERSITY, NY$580,379ZRG1
2018Innate Immune Regulation of the Epithelium in Chronic Rhinosinusitis with Nasal Polyps1R01AI132590-01A1LANE, ANDREW PJOHNS HOPKINS UNIVERSITY, MD$575,894ZRG1
2018FUNGAL PATHOGENESIS OF MODERATE TO SEVERE ASTHMA1R01AI135803-01CORRY, DAVID BKHERADMAND, FARRAHBAYLOR COLLEGE OF MEDICINE, TX$555,952ZRG1
2018Innate-like BCR activity as a template for universal vaccination against influenza virus1R01AI137057-01CHACKERIAN, BRYCE CLINGWOOD, DANIELMASSACHUSETTS GENERAL HOSPITAL, MA$552,569CMIB
2018Understanding the Molecular Genetic Mechanisms of Asthma Risk Loci: IL33, IL1RL1, and GSDMB1R01AI136962-01GORDON, ERIN D.UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$551,981ZRG1
2018Role of Dock8 in Mucosal Immunity1R01AI140626-01JAMES, RICHARD GOFFPILIPONSKY, ADRIAN MSEATTLE CHILDREN'S HOSPITAL, WA$548,230ZRG1
2018Influence of polysialic acid on leukocyte migration1R01AI132733-01A1STAMATOS, NICHOLAS MILTONUNIVERSITY OF MARYLAND BALTIMORE, MD$547,507III
2018ORIGINS AND FUNCTIONS OF UTERINE NATURAL KILLER CELLS IN PREGNANCY1R01AI140397-01A1YOKOYAMA, WAYNE M.WASHINGTON UNIVERSITY, MO$545,181III
2018HLA-DO / H2-O: modulation of MHC-II peptide diversity and Treg population control1R01AI127869-01A1STERN, LAWRENCE J.UNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$541,182CMIA
2018Novel mechanisms of age-enhanced vasculopathy after heart transplantation1R01AI138347-01GOLDSTEIN, DANIEL ROBERTUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$539,907AICS
2018A combined computational and experimental approach to the evolution and role of the DNA sequence environment in targeting mutations to antibody V regions1R01AI132507-01A1MACCARTHY, THOMASSCHARFF, MATTHEW DALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$537,909CMIB
2018Characterization of a distinct NKT subset and its role in influenza responses1R01AI129458-01A1ALBEROLA-ILA, JOSEOKLAHOMA MEDICAL RESEARCH FOUNDATION, OK$537,763ZRG1
2018FDC regulation of self-reactive B cells1R01AI130307-01A1CARROLL, MICHAEL CRAIGBOSTON CHILDREN'S HOSPITAL, MA$531,000CMIA
2018The Role of the Adenosine Receptor in Th Cell Development and Function2R01AI079145-07A1ERNST, PETER B.UNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$517,366ZRG1
2018The Role of Canonical and Non-canonical Autophagy in B Cell Immunity1R01AI135052-01A1BATISTA, FACUNDO DAMIANMASSACHUSETTS GENERAL HOSPITAL, MA$511,515CMIB
2018Humoral Immunity by Anergic B cells1R01AI136534-01A1TORRES, RAUL MARTINUNIVERSITY OF COLORADO DENVER, CO$510,564ZRG1
2018TCR-dependent activation, functional differentiation and memory formation of CD4+ T cells following infection1R01AI137248-01WILLIAMS, MATTHEW AUNIVERSITY OF UTAH, UT$510,138IHD
2018Mechanisms of Allergen-induced Type 2 Immunity2R37AI071106-11KITA, HIROHITOMAYO CLINIC ROCHESTER, MN$503,325ZRG1
2018Gene regulation from the inactive X in activated B cells1R01AI134834-01A1ANGUERA, MONTSERRAT CUNIVERSITY OF PENNSYLVANIA, PA$500,046CMIB
2018Determinants of human neutrophil fate after phagocytosis1R01AI132335-01A1NAUSEEF, WILLIAM M.UNIVERSITY OF IOWA, IA$499,883III
2018Innate Recognition of Allogeneic Non-Self2R01AI099465-06A1LAKKIS, FADI G.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$486,080ZRG1
2018Spatiotemporal Control of T cell Synapse Stabilization and Signaling2R01AI052116-16KRUMMEL, MATTHEW FUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$479,250CMIA
2018Cytokine regulation of skin barrier function2R01AI095282-06KAPLAN, MARK HINDIANA UNIVERSITY INDIANAPOLIS, IN$477,223ZRG1
2018GLUCOSE AND AMINO ACID CATABOLISM IN PLASMA CELL BIOLOGY1R01AI129945-01A1BHATTACHARYA, DEEPTAUNIVERSITY OF ARIZONA, AZ$473,507INMP
2018Lung epithelial cell regulation of immunity to inhaled fungi1R01AI130411-01A1KLEIN, BRUCE STEVENUNIVERSITY OF WISCONSIN-MADISON, WI$470,116IHD
2018Mechanisms of DDO Adjuvancy1R01AI134862-01A1LOPEZ, CAROLINA B.UNIVERSITY OF PENNSYLVANIA, PA$469,510VMD
2018Costimulatory Signals in CD4+ T Cell Activation2R01AI027998-29JENKINS, MARC KEVINUNIVERSITY OF MINNESOTA, MN$465,105CMIB
2018TRANSCRIPTIONAL REGULATION OF ANTIBODY RESPONSES AND IMMUNITY2R01AI099108-06A1BHATTACHARYA, DEEPTAUNIVERSITY OF ARIZONA, AZ$460,500CMIB
2018Mucosal immunity to Toxoplasma gondii1R01AI136538-01YAROVINSKY, FELIXUNIVERSITY OF ROCHESTER, NY$459,876ZRG1
2018Microbe-driven Development of GALT1R01AI140132-01KNIGHT, KATHERINE L.LOYOLA UNIVERSITY CHICAGO, IL$455,340CMIB
2018Molecular control of germinal center selection and affinity maturation1R01AI139117-01VICTORA, GABRIEL DROCKEFELLER UNIVERSITY, NY$454,516CMIB
2018The role of SPNS2 in T cell responses2R01AI085166-06A1SCHWAB, SUSAN RUTHNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$452,238CMIB
2018CD4 T cell, germinal center, and antibody response defects in recurrent tonsillitis1R01AI135193-01A1CROTTY, SHANE PLA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$450,000IHD
2018Regulation of Lung Inflammation by Protein Ubiquitination1R56AI137017-01LIU, YUN-CAILA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$450,000LCMI
2018Neonatal RSV infection and alteration of allergic immune responses1R01AI138348-01HUFFNAGLE, GARY BLUKACS, NICHOLAS WUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$449,626ZRG1
2018Regulation of TH17 plasticity and stemness by mTORC11R01AI131703-01A1CHI, HONGBOST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$448,750HAI
2018Hippo signaling in stable regulatory activity and immune tolerance1R01AI140761-01CHI, HONGBOST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$448,750TTT
2018Role of Vitamin D Metabolism in CRS1R01AI134698-01A1MULLIGAN, JENNIFER KONOPAMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$446,846LCMI
2018Role of DEPTOR in T Cell Activation and Alloimmunity1R01AI136503-01BRISCOE, DAVID M.BOSTON CHILDREN'S HOSPITAL, MA$442,500TTT
2018Vascular-stromal function and regulation in immunity2R01AI079178-06A1LU, THERESA T.HOSPITAL FOR SPECIAL SURGERY, NY$440,000CMIB
2018Characterizing the Mechanism of DPP8/9 Inhibitor-Induced Pyroptosis1R01AI137168-01BACHOVCHIN, DANIELSLOAN-KETTERING INST CAN RESEARCH, NY$429,250III
2018Monocyte Production by Bone Marrow Progenitors1R01AI134987-01GOODRIDGE, HELEN SCEDARS-SINAI MEDICAL CENTER, CA$425,833III
2018BCAP control of lupus pathogenesis via plasmacytoid DC type I IFN production1R56AI132808-01A1HAMERMAN, JESSICA ABENAROYA RESEARCH INST AT VIRGINIA MASON, WA$425,000HAI
2018Regulation and function of innate lymphoid cells in the gut2R01AI095466-06ARTIS, DAVIDWEILL MEDICAL COLL OF CORNELL UNIV, NY$423,750GMPB
2018The role of NLRP6 and DHX15 in control of infection by RNA viruses1R01AI127865-01A1FIKRIG, EROLFLAVELL, RICHARD AYALE UNIVERSITY, CT$418,750IHD
2018B cell/T Follicular Helper cell interactions in progression of Leishmaniasis1R56AI132352-01A1PETERSEN, CHRISTINE AUNIVERSITY OF IOWA, IA$411,744IHD
2018Mechanisms by which commensal dysbiosis drives allergic responses to food1R56AI134923-01A1NAGLER, CATHRYN RUNIVERSITY OF CHICAGO, IL$405,000ZRG1
2018Altered innate leukocyte programming dynamics in sepsis1R01AI136386-01LI, LIWUVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$402,500III
2018Identifying novel regulatory pathways underlying T helper 1 cell immune responses1R01AI134972-01A1OESTREICH, KENNETH JOSEPHVIRGINIA POLYTECHNIC INST AND ST UNIV, VA$400,026CMIB
2018Regulation of Ubiquitination and Arthritis1R01AI135198-01A1MA, AVERIL IUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$399,792HAI
2018Organ-specific autoimmunity resulting from two genetic defects in tolerance1R01AI138479-01DEFRANCO, ANTHONY LUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$399,583TTT
2018Regulation of IgE responses by B cell receptor signaling1R01AI130470-01A1ALLEN, CHRISTOPHER DAVID CABALLEROUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$396,250CMIB
2018TCR signal strength and iNKT cell subset development1R01AI130198-01A1GAPIN, LAURENTUNIVERSITY OF COLORADO DENVER, CO$392,812CMIB
2018Functional and Structural Dissection of Inflammasome Activation2R37AI075039-11VANCE, RUSSELL EUNIVERSITY OF CALIFORNIA BERKELEY, CA$392,500IHD
2018Regulation of IL10 production in CD8+ T cells during Flu infection by tyrosine kinase Itk1R01AI138570-01A1AUGUST, AVERYCORNELL UNIVERSITY, NY$388,829IHD
2018Regulation of T cell activation and exhaustion by Tim-31R01AI138504-01A1KANE, LAWRENCE P.UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$388,425CMIB
2018Akt controls alternative splicing in T helper call fate decisions1R01AI125513-01A1MOREL, PENELOPE ANNEUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$386,996CMIA
2018Role of Semaphorin 4A in Allergic Inflammation1R01AI122631-01A1KEEGAN, ACHSAH D.UNIVERSITY OF MARYLAND BALTIMORE, MD$386,250ZRG1
2018Biomaterials to study tolerance immune induction kinetics1R01AI137525-01A1AINSLIE, KRISTY MUNIV OF NORTH CAROLINA CHAPEL HILL, NC$385,768NANO
2018Mechanisms of iNKT cell anti-viral adjuvancy1R01AI136500-01A1GUMPERZ, JENNY E.UNIVERSITY OF WISCONSIN-MADISON, WI$382,500IHD
2018Linking diet, gut microbiota and autoimmune disease: Bacteria induced phytoestrogen metabolites impact immune function in Experimental Autoimmune Encephalitis1R01AI137075-01MANGALAM, ASHUTOSH KUMARUNIVERSITY OF IOWA, IA$381,250HAI
2018Role of proteasome activity in adaptive immunity1R01AI129973-01A1CHANG, JOHN TUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$378,789IHD
2018Regulation of T cell immunity to viral infection2R01AI072117-11GOLDRATH, ANANDA WUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$376,650ZRG1
2018GGT Targeting Suppresses Mast Cell Activation by IgE and IL-331R01AI138495-01RYAN, JOHN JVIRGINIA COMMONWEALTH UNIVERSITY, VA$371,369III
2018Aging and IL-7 mediated CD8+ T cell survival1R01AG056728-01A1KANG, INSOOYALE UNIVERSITY, CT$368,500ASG
2018Structural, functional, and mechanistic anlaysis of autoreactive CD8 T cells1R01AI123730-01A1ALMO, STEVEN C.DILORENZO, TERESA PALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$367,866HAI
2018Natural killer cell cytotoxicity against intracellular bacteria1R01AI133236-01A1MIAO, EDWARD AUNIV OF NORTH CAROLINA CHAPEL HILL, NC$301,323IHD
2018Deubiquitination in Immune Regulation1R56AI132765-01A1LIU, YUN-CAILA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$270,000CMIB
2018Enhancing Pathogen-specific Memory CD8+ T cell Responses in Vivo2R01AI103338-07A1LAUVAU, GREGOIRE STEPHANEALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$258,228CMIB
2018Type 2 Mucosal Inflammation Elicited Through an LTE4/GPR99-Dependent Pathway1R56AI134989-01BARRETT, NORA AMANDABRIGHAM AND WOMEN'S HOSPITAL, MA$246,962LCMI
2017Mechanisms of IL-6 mediated T cell pathogenesis in autoimmunity1R01AI132774-01BUCKNER, JANE HOYTBENAROYA RESEARCH INST AT VIRGINIA MASON, WA$841,539HAI
2017Epigenome-wide association study of childhood asthma1R01AI121426-01A1ARSHAD, SYED HASANPETERS, BJOERNVIJAYANAND, PANDURANGANLA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$812,769ZRG1
2017Understanding measles vaccine failure (and success) in Southern India1R01AI121054-01JACOB, JOSHYKENNEDY, RICHARD BMAYO CLINIC ROCHESTER, MN$807,900IRAP
2017Biology of ฮฑ-linked glycosylceramides in the immune system1R01AI123130-01A1TEYTON, LUCSCRIPPS RESEARCH INSTITUTE, THE, CA$746,384CMIA
2017Sputum Microbial Markers of Type 2-Low Asthma1R01AI129958-01A1HUANG, YVONNE JEANUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$732,382IRAP
2017The Role of Group 3 Innate Lymphoid cells (ILC3) in Tuberculosis1R01AI134236-01COLONNA, MARCOKHADER, SHABAANA A.WASHINGTON UNIVERSITY, MO$712,802ZRG1
2017Structure and Activation of a Multiprotein Signaling Complex1R01AI129893-01A1MARIUZZA, ROY AORBAN, JOHNVIGNALI, DARIO AAUNIV OF MARYLAND, COLLEGE PARK, MD$711,031MSFC
2017Diversity of TFH cells and DSA generation after kidney transplantation1R01AI130010-01METES, DIANA MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$689,885TTT
2017Cellular and molecular mechanisms of IgE cell memory in allergic responses1R01AI130343-01CUROTTO DE LAFAILLE, MARIA ALAFAILLE, JUANNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$622,041ZRG1
2017Cis-Regulatory Circuits for ILC Function and Plasticity1R56AI134035-01COLONNA, MARCOOLTZ, EUGENE MWASHINGTON UNIVERSITY, MO$621,424CMIA
2017Eliciting lung-localized CD4 T cell responses against Mycobacterium tuberculosis in preventive and post-exposure settings1R01AI134246-01ANDERSEN, PETER LAWAETZURDAHL, KEVIN BSEATTLE BIOMEDICAL RESEARCH INSTITUTE, WA$609,293ZRG1
2017PARP9-DTX3L Control Of Viral Infection and Airway Disease1R01AI130591-01HOLTZMAN, MICHAEL JWASHINGTON UNIVERSITY, MO$608,777LCMI
2017Viral Mediated Type I Interferon Induction2R01AI069120-11A1CHENG, GENHONGUNIVERSITY OF CALIFORNIA LOS ANGELES, CA$605,146III
2017T cell receptor-activated autophagy as a regulator of T cell effector responses1R01AI125552-01A1CONRADS, THOMAS PATRICKHE, YOU-WENSCHAEFER, BRIANHENRY M. JACKSON FDN FOR THE ADV MIL/MED, MD$604,437CMIB
2017Regulation of T cell development by HDAC31R56AI122746-01A1SHAPIRO, VIRGINIA SMITHMAYO CLINIC ROCHESTER, MN$602,939CMIB
2017Regulation of Tfh cell differentiation and humoral immunity1R01AI130232-01A1HU, HUIUNIVERSITY OF ALABAMA AT BIRMINGHAM, AL$573,134CMIB
2017Generating protective immunity to Staphylococcus aureus1R01AI127406-01A1LIU, GEORGE YMARTINS, GISLAINE AUNDERHILL, DAVID M.CEDARS-SINAI MEDICAL CENTER, CA$570,400ZRG1
2017Tocopherol regulation of the development of responsiveness to allergen early in life1R01AI127695-01A1COOK-MILLS, JOAN MNORTHWESTERN UNIVERSITY AT CHICAGO, IL$559,039ZRG1
2017The Role of Interferon Regulatory Factor 5 in the Pathogenesis of SLE1R01AI130199-01A1RIFKIN, IAN RBOSTON MEDICAL CENTER, MA$557,386HAI
2017Macrophage differentiation and disease outcome in influenza infection1R01AI123371-01A1VOGEL, STEFANIE N.UNIVERSITY OF MARYLAND BALTIMORE, MD$555,603IHD
2017Defining the impact of pre-existing memory T cells in human immunity1R01AI134879-01SU, LAURAUNIVERSITY OF PENNSYLVANIA, PA$554,629VMD
2017Host's and microbiota's contribution to sexual dimorphism of autoimmunity1R01AI127411-01A1CHERVONSKY, ALEXANDER VUNIVERSITY OF CHICAGO, IL$551,958HAI
2017NATURAL KILLER CELL CONTROL OF MURINE CYTOMEGALOVIRUS INFECTION1R01AI131680-01A1YOKOYAMA, WAYNE M.WASHINGTON UNIVERSITY, MO$548,096IHD
2017T cell maintenance: molecular mediators of T cell differentiation and survival2R01AI067545-11A1GOLDRATH, ANANDA WUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$542,500CMIA
2017Regulation of Nfil3 in innate lymphocyte-mediated host immunity1R01AI130043-01SUN, JOSEPH CHAI-YUENSLOAN-KETTERING INST CAN RESEARCH, NY$541,694IHD
2017Regulation of Lupus by Cytosolic DNA Sensors1R01AI128358-01FITZGERALD, KATHERINE A.MARSHAK-ROTHSTEIN, ANNUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$535,551ACTS
2017Immune surveillance of antigen processing pathway1R01AI130210-01SHASTRI, NILABHUNIVERSITY OF CALIFORNIA BERKELEY, CA$535,188CMIA
2017Regulation of Gut Innate Lymphoid Cells by Ahr1R01AI132391-01ZHOU, LIANGUNIVERSITY OF FLORIDA, FL$534,256ZRG1
2017The control of allergic immune responses by follicular regulatory T cells1R01AI132771-01DENT, ALEXANDER LINDIANA UNIVERSITY INDIANAPOLIS, IN$533,777ZRG1
2017Natural Killer Cell Tolerance to Self1R01AI129545-01A1YOKOYAMA, WAYNE M.WASHINGTON UNIVERSITY, MO$528,312TTT
2017Innate Immune Mechanisms of Non-infectious Lung Inflammation2R01AI052201-12A1NOBLE, PAUL WESLEYCEDARS-SINAI MEDICAL CENTER, CA$525,054LCMI
2017Dynamics of Antigen-Driven Selection in Germinal Centers1R01AI119006-01A1VICTORA, GABRIEL DROCKEFELLER UNIVERSITY, NY$523,550CMIB
2017Mechanisms of IL-33 secretion in allergic diseases1R01AI128729-01KITA, HIROHITOO'GRADY, SCOTT M.MAYO CLINIC ROCHESTER, MN$522,735ZRG1
2017Unconventional sources of peptides for antigen presentation1R01AI121174-01A1SHASTRI, NILABHUNIVERSITY OF CALIFORNIA BERKELEY, CA$516,094CMIA
2017Molecular mechanisms of IL-33 cytokine signaling1R01AI132766-01SUNDBERG, ERIC JOHNUNIVERSITY OF MARYLAND BALTIMORE, MD$515,964CMIA
2017The natural killer cell response against mouse cytomegalovirus infection2R01AI100874-06SUN, JOSEPH CHAI-YUENSLOAN-KETTERING INST CAN RESEARCH, NY$512,779IHD
2017Regulation of Follicular T cell Responses in the Lung by Ion Channels1R01AI130143-01A1FESKE, STEFANNEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY$505,456LCMI
2017Distinct mast cell responses in male and female SJL mice underlie sex dimorphic EAE susceptibility1R01AI128292-01A1BROWN, MELISSA ANORTHWESTERN UNIVERSITY AT CHICAGO, IL$504,341HAI
2017Regulation of cutaneous immunity and tissue-repair by a specialized population of CD4+ T cells1R01AI127726-01A1CAMPBELL, DANIEL JGRATZ, IRIS KARINABENAROYA RESEARCH INST AT VIRGINIA MASON, WA$503,184ACTS
2017GSDMB and mucosal allergic response1R01AI124236-01A1BROIDE, DAVID HUNIVERSITY OF CALIFORNIA, SAN DIEGO, CA$499,013ZRG1
2017In Vivo Prevention of Murine GVHD2R37AI034495-25BLAZAR, BRUCE RUNIVERSITY OF MINNESOTA, MN$497,610CII
2017The Role of macrophages in chorioamnionitis and group B streptococcal infections1R01AI134036-01ARONOFF, DAVID MVANDERBILT UNIVERSITY MEDICAL CENTER, TN$495,463ZRG1
2017Role of osteopontin in innate immunity during infections and inflammation2R01AI088100-06SHINOHARA, MARI L.DUKE UNIVERSITY, NC$482,816III
2017Role of nociceptive sensory neuron/mast cell interactions in cutaneous allergic inflammation1R01AI132494-01GALLI, STEPHEN JOSEPHSTANFORD UNIVERSITY, CA$481,734ZRG1
2017Regulation of Normal and Pathogenic B Cell Proliferation by a c-Myc-initiated Transcription Factor Cascade1R01AI130152-01A1EGAWA, TAKESHIWASHINGTON UNIVERSITY, MO$471,521CMIA
2017Role of IL-15 and IL-23 in colitis1R01AI133885-01OUKKA, MOHAMEDSEATTLE CHILDREN'S HOSPITAL, WA$470,750ZRG1
2017Binding and Presentation of Lipid Antigens by CD12R01AI045889-17A1PORCELLI, STEVEN AALBERT EINSTEIN COLLEGE OF MEDICINE, INC, NY$467,416CMIA
2017UNIQUE ROLES OF ANTIGEN PRESENTING CELLS ON T CELL TOLERANCE AND AUTOIMMUNITY2R01AI079187-10A1HSIEH, CHYI SWASHINGTON UNIVERSITY, MO$457,500ZRG1
2017Novel Requirements for Akt1 in T Cell Commitment2R01AI089805-07HUANG, YINA HSINGDARTMOUTH COLLEGE, NH$457,266CMIA
2017Regulation of Liver DC Function and Transplant Tolerance1R01AI118777-01A1THOMSON, ANGUS WUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$455,628TTT
2017Epigenetic control of Foxp3 expression in induced T regulatory cells1R01AI128589-01A1RAO, ANJANALA JOLLA INSTITUTE FOR IMMUNOLOGY, CA$450,000CMIA
2017Inflammatory Caspases in Innate Immunity and Inflammation2R37AI101935-06KANNEGANTI, THIRUMALA-DEVIST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$448,750ZRG1
2017Survival Function of the Fadd-Caspase-8-Flip Complex2R37AI044828-19GREEN, DOUGLAS R.ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$448,750CSRS
2017Establishment, maintenance, and consequences of asymmetric cell division in T cells1R01AI123322-01A1GREEN, DOUGLAS R.ST. JUDE CHILDREN'S RESEARCH HOSPITAL, TN$447,500CMIB
2017FUNCTIONAL ANALYSIS OF PATHOGENIC AND PROTECTIVE PEANUT ALLERGEN-SPECIFIC HUMAN ANTIBODIES1R01AI125567-01A1BOYD, SCOTT DEXTERSTANFORD UNIVERSITY, CA$444,233ZRG1
2017Macrophage Redox State in Sterilizing and Injurious Inflammation1R01AI131267-01A1BONINI, MARCELO G.UNIVERSITY OF ILLINOIS AT CHICAGO, IL$441,242LIRR
2017Mechanism and Targeting of V(D)J Recombination2R01AI032524-26SCHATZ, DAVID G.YALE UNIVERSITY, CT$439,551CMIA
2017Role of nuclear factor TOX in lymphocyte development2R01AI054977-11A1KAYE, JONATHAN GCEDARS-SINAI MEDICAL CENTER, CA$437,500CMIB
2017Immunological and Microbial Mechanisms in Food Allergy1R01AI126915-01CHATILA, TALAL AMINEBOSTON CHILDREN'S HOSPITAL, MA$434,500ZRG1
2017Regulation of the follicular T-cell response to autoimmunity2R01AI048125-10CANTOR, HARVEYDANA-FARBER CANCER INST, MA$433,265ZRG1
2017Eosinophil functions in allergic gastrointestinal diseases1R01AI121186-01A1SPENCER, LISA ANNBETH ISRAEL DEACONESS MEDICAL CENTER, MA$432,500III
2017Molecular study mouse virus resistance mechanisms2R01AI050072-15BROWN, MICHAEL GUNIVERSITY OF VIRGINIA, VA$432,438ZRG1
2017Regulation of pathogenic T cells in EAE1R01AI129548-01BETTELLI, ESTELLEBENAROYA RESEARCH INST AT VIRGINIA MASON, WA$428,750ZRG1
2017T regulatory cell subsets at the microbial interface: determinism and function1R01AI125603-01A1BENOIST, CHRISTOPHE O.HARVARD MEDICAL SCHOOL, MA$423,750CMIA
2017Structural Basis of Immune Cell Receptor Function2R01AI037581-21A1WAGNER, GERHARDHARVARD MEDICAL SCHOOL, MA$422,106BBM
2017Role of Clec2d-DAMP interactions in the pathophysiology of tissue injury and sepsis1R01AI129966-01ROCK, KENNETH LUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$418,750SAT
2017An Immune Surveillance Network in C. elegans1R01AI130289-01A1PUKKILA-WORLEY, READUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$418,750III
2017Targeting of somatic hypermutation in the genome1R01AI127642-01A1SCHATZ, DAVID G.YALE UNIVERSITY, CT$417,987CMIB
2017Modulation of Chronic Th2 inflammation by the CCR8 Receptor-Ligand Pathway1R01AI121248-01A1ISLAM, SABINA AMASSACHUSETTS GENERAL HOSPITAL, MA$416,850ZRG1
2017Role of the gender biased transcription factor VGLL3 in promoting autoimmune responses in SLE1R01AI130025-01GUDJONSSON, JOHANN ELIUNIVERSITY OF MICHIGAN AT ANN ARBOR, MI$416,214ACTS
2017Probing the mechanistic basis for T cell fate decisions (R01)2R01AI101053-05A1KUHNS, MICHAEL SUNIVERSITY OF ARIZONA, AZ$416,041CMIB
2017Role of Hofbauer Cells in Fetal Infection/Inflammation1R01AI131613-01ABRAHAMS, VIKKI MGULLER, SETH M.YALE UNIVERSITY, CT$413,817ZRG1
2017Cellular mechanisms by which exhausted T cell responses are restored1R01AI123349-01A1MEMPEL, THORSTEN ROMANMASSACHUSETTS GENERAL HOSPITAL, MA$409,750CMIB
2017Dysregulated sensing of invertebrate tropomyosin through dectin-1 confers susceptibility to type-2-mediated allergic diseases1R01AI127644-01A1LAJOIE, STEPHANEJOHNS HOPKINS UNIVERSITY, MD$408,646ZRG1
2017Defining the non-apoptotic role of Caspase-8 activity in anti-bacterial immune defense1R01AI128530-01BRODSKY, IGOR EUNIVERSITY OF PENNSYLVANIA, PA$407,423HIBP
2017MMP13 expression and function in allergic inflammation1R01AI127768-01PARK, JIN MOMASSACHUSETTS GENERAL HOSPITAL, MA$407,286ZRG1
2017Storage and recall of human B cell memory of influenza over tissues and time1R01AI127877-01BOYD, SCOTT DEXTERSTANFORD UNIVERSITY, CA$407,050ZRG1
2017Innate mechanisms of regulation of memory Th17 cell responses1R01AI123176-01A1PASARE, CHANDRASHEKHARUT SOUTHWESTERN MEDICAL CENTER, TX$405,000CMIB
2017Understanding ERAP molecular mechanism of MHC I antigen processing1R01AI114467-01A1BOUVIER, MARLENEUNIVERSITY OF ILLINOIS AT CHICAGO, IL$399,750CMIB
2017Modulation of innate immune cells to create transplant tolerance2R01AI080779-07LI, XIAN CHANGMETHODIST HOSPITAL RESEARCH INSTITUTE, TX$398,750TTT
2017Regulation of Th2 differentiation by skin-resident dendritic cells1R01AI132576-01KUMAMOTO, YOSUKERBHS-NEW JERSEY MEDICAL SCHOOL, NJ$397,500ZRG1
2017Mechanisms of E protein transcription factor-dependent iNKT cell expansion and differentiation1R01AI123396-01A1KEE, BARBARA L.UNIVERSITY OF CHICAGO, IL$396,945CMIA
2017The role of IL-27/Lag3 axis in regulating Foxp3+ regulatory T cell function1R01AI125247-01A1MIN, BOOKICLEVELAND CLINIC LERNER COM-CWRU, OH$396,250HAI
2017Regulation of Innate Dendritic Cell CTLA-41R01AI127387-01A1DECKER, WILLIAM KARLBAYLOR COLLEGE OF MEDICINE, TX$396,250III
2017Thymic medullary epithelial cell turnover and control of immune tolerance2R37AI097457-06A1ANDERSON, MARK SUNIVERSITY OF CALIFORNIA, SAN FRANCISCO, CA$396,250TTT
2017GLP-1R signaling in allergic inflammation1R01AI124456-01A1NISWENDER, KEVIN DPEEBLES, RAY STOKESVANDERBILT UNIVERSITY MEDICAL CENTER, TN$395,000LCMI
2017Orchestrating intestinal immunity through microbiota-CX3CR1+ cell interactions1R01AI125264-01A1DIEHL, GRETCHEN EBAYLOR COLLEGE OF MEDICINE, TX$393,325III
2017Th9 cells in immediate hypersensitivity1R01AI129241-01KAPLAN, MARK HINDIANA UNIVERSITY INDIANAPOLIS, IN$391,875ZRG1
2017Distinct pathways for MR1 antigen presentation upon infection with intracellular versus extracellular pathogens1R01AI129976-01HARRIFF, MELANIE JOREGON HEALTH & SCIENCE UNIVERSITY, OR$390,733ZRG1
2017Mechanisms of GM-CSF effect in CNS autoimmune demyelination2R01AI124386-10A1ROSTAMI, A.M.THOMAS JEFFERSON UNIVERSITY, PA$390,000CNBT
2017Role of Aiolos in eosinophilic asthma1R01AI130033-01FULKERSON, PATRICIA CHANDHOKCINCINNATI CHILDRENS HOSP MED CTR, OH$390,000ZRG1
2017Mechanisms of successful vaccine adjuvants1R01AI127970-01A1MITCHELL, THOMAS C.UNIVERSITY OF LOUISVILLE, KY$385,000ZRG1
2017Mechanisms of islet transplant immune tolerance1R56AI130330-01A1ABDULREDA, MIDHAT HUNIVERSITY OF MIAMI SCHOOL OF MEDICINE, FL$383,750TTT
2017Regulation of memory T cell trafficking by core 2 O-glycan synthesis1R01AI132404-01A1NOLZ, JEFFREY C.OREGON HEALTH & SCIENCE UNIVERSITY, OR$382,270IHD
2017Restoring Immune Tolerance in a Model of Multiple Sclerosis1R01AI128074-01HOFFMAN, BRAD EUNIVERSITY OF FLORIDA, FL$381,250GDD
2017Epithelial Responses to Bacterial Invasion2R01AI077600-06MILLER, MARK JAMESWASHINGTON UNIVERSITY, MO$381,250IHD
2017Eosinophils as Regulators of Host Immunity against Influenza Infections1R01AI125481-01A1SAMARASINGHE, AMALIUNIVERSITY OF TENNESSEE HEALTH SCI CTR, TN$380,000IHD
2017Non-coding RNA and ADP-ribosylation in Antiviral Defense1R01AI123231-01A1SULLIVAN, CHRISTOPHER S.UNIVERSITY OF TEXAS AT AUSTIN, TX$378,820VIRB
2017Investigating the transfer of miRNAs by exosomes during inflammation1R01AI123106-01A1O'CONNELL, RYAN MUNIVERSITY OF UTAH, UT$378,438HAI
2017Functional protein networks underlying T cell growth, proliferation and differentiation1R01AI123193-01A1WAN, YISONGUNIV OF NORTH CAROLINA CHAPEL HILL, NC$377,975CMIB
2017Mechanisms of Colonization and Persistence by Neisseria1R56AI124665-01A1FRELINGER, JEFFREY ALLENSO, MAGDALENE YUNIVERSITY OF ARIZONA, AZ$377,605ZRG1
2017Molecular chaperones and immune tolerance2R01AI077283-11A1LI, ZIHAIMEDICAL UNIVERSITY OF SOUTH CAROLINA, SC$373,750TTT
2017Inflammatory B Cells Defined by TIM-4 in the Alloimmune Response1R56AI130034-01ROTHSTEIN, DAVID MUNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA$371,457TTT
2017Mucosal associated invariant T (MAIT) cells in Vibrio cholerae infection and vaccination1R01AI130378-01A1LEUNG, DANIEL TEDUNIVERSITY OF UTAH, UT$369,782ZRG1
2017Memory T cell development and survival in T cell responses of older individuals1R01AI129191-01A1GORONZY, JORG JPALO ALTO VETERANS INSTIT FOR RESEARCH, CA$360,701ASG
2017The Role of Ubiquitin and Ubiquitin-Like Molecules in Direct Antigen Presentation1R01AI130059-01DOLAN, BRIAN PAULOREGON STATE UNIVERSITY, OR$354,450CMIA
2017Antigenic landscape of the human helminth IgE antibody response1R01AI130459-01SMITH, SCOTT ALANVANDERBILT UNIVERSITY MEDICAL CENTER, TN$350,340ZRG1
2017AhR ligands in epigenetic dysregulation of T cells1R01AI123947-01A1NAGARKATTI, MITZINAGARKATTI, PRAKASH SUNIVERSITY OF SOUTH CAROLINA AT COLUMBIA, SC$333,750SIEE
2017Migration and function of cutaneous B cells1R01AI127389-01DEBES, GUDRUN PHILOMENATHOMAS JEFFERSON UNIVERSITY, PA$312,000ACTS
2017Activation of Insect Immunity by Gram-negative Bacteria2R01AI060025-14A1SILVERMAN, NEALUNIV OF MASSACHUSETTS MED SCH WORCESTER, MA$307,324III
2017Targeting follicular helper CD4 T cells in SLE1R01AI128901-01MOREL, LAURENCEUNIVERSITY OF FLORIDA, FL$305,000HAI

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